Trial of Oxytocin Alone Versus Oxytocin and Propranolol for the Treatment of Abnormal Labor
Information source: University of California, Irvine
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Dysfunctional Labor
Intervention: Propranolol (Drug); IV Placebo (Other)
Phase: Phase 2
Sponsored by: University of California, Irvine
Official(s) and/or principal investigator(s):
Leah R Battista, MD, Principal Investigator, Affiliation: University of California, Irvine
The purpose of this study is to determine whether propranolol is better than oxytocin for
the treatment of labor abnormalities. The endpoint is the rate of vaginal delivery
experienced by women receiving prolonged oxytocin versus propranolol.
Official title: Placebo-Controlled Randomized Trial of Oxytocin Alone Versus Oxytocin and Propranolol for the Treatment of Dysfunctional Labor
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
Vaginal delivery rates
Cesarean section rates
This trial was designed to test if propranolo can reduce the c section rate for dysfuctional
labor. Due to stringent inclution and exclusion criteria and low enrollment the study was
Minimum age: 18 Years.
Maximum age: N/A.
- Must be term pregnancy (> 37 weeks)
- Vertex presentation
- Active labor (4-5 centimeters dilated)
- Heart disease
- Currently taking propranolol
- Contraindications to labor or vaginal delivery
- Multiple gestations
Locations and Contacts
Long Beach Memorial Medical Center, Long Beach, California 90806, United States
Starting date: January 2004
Last updated: December 5, 2014