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Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Tamsulosin

Information source: Frederiksberg University Hospital
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Cataract

Phase: N/A

Status: Completed

Sponsored by: Frederiksberg University Hospital

Summary

The purpose of this study is to determine whether corneal endothelium cell loss during cataract surgery is higher in patients taking Tamsulosin.

Clinical Details

Official title: Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Systemic Sympathetic Alfa-1-a-antagonist Medication (Tamsulosin)

Study design: Observational Model: Case Control, Time Perspective: Prospective

Primary outcome: corneal endothelium cell loss

Detailed description: Cataract surgery in patients taking Tamsulosin is regarded as more challenging for the surgeon because Intraoperative Floppy Iris Syndrome (IFIS) might occur. However, the question is whether this has any practical implication for the outcomes of surgery. In this study we investigate whether cornea is damage during surgery on Tamsulosin patient. In an observational study 30 cataract patients taking Tamsulosin is compared to 30 patients not taking Tamsulosin, but otherwise similar. Number of patients is based on power calculation. Cornea is examined by specular microscopy.

Eligibility

Minimum age: N/A. Maximum age: N/A. Gender(s): Male.

Criteria:

Inclusion Criteria:

- cataract needing surgery

Exclusion Criteria:

- glaucoma

- corneal scarring

- diabetes

- uveitis

Locations and Contacts

Frederiksberg University Hospital, Frederiksberg 2000, Denmark
Additional Information

Starting date: June 2009
Last updated: July 19, 2011

Page last updated: August 20, 2015

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