Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Tamsulosin
Information source: Frederiksberg University Hospital
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Cataract
Phase: N/A
Status: Completed
Sponsored by: Frederiksberg University Hospital
Summary
The purpose of this study is to determine whether corneal endothelium cell loss during
cataract surgery is higher in patients taking Tamsulosin.
Clinical Details
Official title: Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Systemic Sympathetic Alfa-1-a-antagonist Medication (Tamsulosin)
Study design: Observational Model: Case Control, Time Perspective: Prospective
Primary outcome: corneal endothelium cell loss
Detailed description:
Cataract surgery in patients taking Tamsulosin is regarded as more challenging for the
surgeon because Intraoperative Floppy Iris Syndrome (IFIS) might occur. However, the
question is whether this has any practical implication for the outcomes of surgery. In this
study we investigate whether cornea is damage during surgery on Tamsulosin patient. In an
observational study 30 cataract patients taking Tamsulosin is compared to 30 patients not
taking Tamsulosin, but otherwise similar. Number of patients is based on power calculation.
Cornea is examined by specular microscopy.
Eligibility
Minimum age: N/A.
Maximum age: N/A.
Gender(s): Male.
Criteria:
Inclusion Criteria:
- cataract needing surgery
Exclusion Criteria:
- glaucoma
- corneal scarring
- diabetes
- uveitis
Locations and Contacts
Frederiksberg University Hospital, Frederiksberg 2000, Denmark
Additional Information
Starting date: June 2009
Last updated: July 19, 2011
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