The Effect of Epidural Steroid Injections on Glycemic Control in Diabetic Patients According to the Doses of Steroids
Information source: Samsung Medical Center
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Low Back Pain
Intervention: epidural steroid injection with Triamcinolone 40mg (Other); Selective transforaminal epidural block with triamcinolone 20 mg (Other); caudal epidural steroid injection with Triamcinolone 20mg (Other); Selective transforaminal epidural block with triamcinolone 40 mg (Other)
Phase: N/A
Status: Completed
Sponsored by: Samsung Medical Center
Summary
There has been no reports of the effect of various kinds of steroid or various dose of
steroid which are commonly used in the clinical setting. Previous studies have simply shown
that the blood glucose level is elevated in diabetes patients and did not show or suggest
the adequate strategy of epidural steroid injection in diabetes patients regarding steroid
type, dosage or injection interval. Therefore, the investigators tried to evaluate the
effect of different dosage of triamcinolone, which is a commonly used steroid in epidural
steroid injection, on the blood glucose level.
Clinical Details
Official title: The Effect of Epidural Steroid Injections on Glycemic Control in Diabetic Patients According to the Doses of Steroids
Study design: Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject)
Primary outcome: fasting blood glucose levelfasting blood glucose level fasting blood glucose level fasting blood glucose level fasting blood glucose level fasting blood glucose level fasting blood glucose level fasting blood glucose
Secondary outcome: post-prandial glucose levelvisual analogue scale of subjective pain
Detailed description:
It is well known that blood glucose level is elevated in diabetes patients more than
non-diabetes patients who underwent the epidural steroid injection. However, there has been
no reports of the effect of various kinds of steroid or various dose of steroid which are
commonly used in the clinical setting. Previous studies have simply shown that the blood
glucose level is elevated in diabetes patients and did not show or suggest the adequate
strategy of epidural steroid injection in diabetes patients regarding steroid type, dosage
or injection interval. Therefore, the investigators tried to evaluate the effect of
different dosage of triamcinolone, which is a commonly used steroid in epidural steroid
injection, on the blood glucose level.
Eligibility
Minimum age: 20 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- subjects who undergo epidural steroid injection (caudal epidural injection or
selective transforaminal block) in the pain medicine outpatient clinic
- subjects older than 20 yrs.
Exclusion Criteria:
- ASA (American society of Anesthesiologists class) III or more
- severe cardiopulmonary disease or brain disorder
- Subjects diagnosed uncontrolled diabetes with complications
- subjects undergoing hormone therapy
- subjects with active infection
- subjects with pregnancy
- subjects with recent stress condition such as surgery or trauma
- subjects with active neurologic disorder
- those with anticoagulation therapy
Locations and Contacts
Samsung Medical Center, Seoul 135-710, Korea, Republic of
Additional Information
Starting date: September 2011
Last updated: December 24, 2013
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