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Keratometric and Fluorescein Tear Breakup Time

Information source: University of Arkansas
Information obtained from ClinicalTrials.gov on October 19, 2009
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Dry Eye

Phase: N/A

Status: Recruiting

Sponsored by: University of Arkansas

Overall contact:
Richard A. Harper, MD, Phone: 501 686-5150, Email: harperricharda@uams.edu


The purpose of the research is to determine if putting fluorescein onto the eye (most common test done for dry eye syndrome) is an accurate way to measure dry eye symptoms. The investigators can avoid placing any foreign substance into the eye by using a manual keratometer. Therefore, the investigators want to compare the measurements of tear break up time using fluorescein with using a manual keratometer and then compare these measurements to a validated dry eye symptoms questionnaire.

Measuring tear break up time using a manual keratometer is a better way to estimate dry eye symptoms than using fluorescein to measure tear break up time.

Clinical Details

Official title: Comparison of Keratometric Tear Break Up Time to Fluorescein Tear Break Up Time

Study design: Case-Only, Prospective

Primary outcome: The investigators believe the that keratometric tear break up time will be a better method of quantifying dry eye symptoms as compared to current clinical methods. These results are reasonably expected.


Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.


Inclusion Criteria:

- An adult, between ages 18-99

- An adult who is able to understand study instructions

Exclusion Criteria:

- An adult with corneal pathology that prevents accurate assessment of keratometric or

fluorescein tear break up time.

- An adult with an allergy to fluorescein, a very common eye dye that detects defects

in the cornea.

- The inability to answer questions on your own.

Locations and Contacts

Richard A. Harper, MD, Phone: 501 686-5150, Email: harperricharda@uams.edu

Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States; Recruiting
Richard Harper, MD, Principal Investigator
Grant Corning, MD, Sub-Investigator
Additional Information

Starting date: February 2009
Ending date: December 2010
Last updated: March 2, 2009

Page last updated: October 19, 2009

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