Emergency Department Use of Nebulized Budesonide as an Adjunct to Standardized Therapy in Acutely Ill Adults With Refractory Asthma
Information source: North Shore Long Island Jewish Health System
Information obtained from ClinicalTrials.gov on November 03, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Asthma
Intervention: Budesonide (Drug); albuterol (Drug); Ipratropium bromide (Drug); Prednisone (Drug)
Phase: Phase 3
Status: Recruiting
Sponsored by: North Shore Long Island Jewish Health System Official(s) and/or principal investigator(s):
Robert Silverman, MD, Principal Investigator, Affiliation: North Shore-LIJ Health System
Overall contact:
Emily Baneman, BA, Phone: 718-470-7501, Email: emily.baneman@gmail.com
Summary
To determine whether adding nebulized inhaled steroids to the standard care of acutely ill ED
patients with refractory acute asthma helps improve FEV1 and decrease the need for
hospitalization.
Clinical Details
Official title: Emergency Department Use of Nebulized Budesonide as an Adjunct to Standardized Therapy in Acutely Ill Adults With Refractory Asthma: a Randomized, Double-Blinded, Placebo-Controlled Trial
Study design: Treatment, Randomized, Double Blind (Subject, Caregiver, Investigator), Placebo Control, Parallel Assignment, Safety/Efficacy Study
Primary outcome: FEV1
Secondary outcome: Hospitalization
Eligibility
Minimum age: 18 Years.
Maximum age: 60 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- FEV1<50% predicted after bronchodilator therapy, age 18-60, presenting to an emergency
department with acute asthma
Exclusion Criteria:
- other chronic lung disease, >15 pack years smoking
Locations and Contacts
Emily Baneman, BA, Phone: 718-470-7501, Email: emily.baneman@gmail.com
Long Island Jewish Medical Center, Queens, New York 11042, United States; Recruiting
Robert Silverman, MD, Principal Investigator
Jacobi Medical Center, Bronx, New York 10461, United States; Recruiting
Additional Information
Starting date: September 2007
Ending date: December 2008
Last updated: February 12, 2008
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