DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Sevoflurane in Electroconvulsive Therapy

Information source: Inonu University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: ECT; Anesthesia

Intervention: sevorane (Drug)

Phase: Phase 4

Status: Completed

Sponsored by: Inonu University

Official(s) and/or principal investigator(s):
Huseyin Toprak, Professor, Principal Investigator, Affiliation: Inonu University


The purpose of the study was to investigate the effects of different doses of sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure, hemodynamic response and recovery profiles

Clinical Details

Official title: The Comparision of Different Doses of Sevoflurane for Induction of General Anesthesia in Electroconvulsive Therapy

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure

Secondary outcome: sevoflurane used in electroconvulsive therapy (ECT) on hemodynamic response.

Detailed description: Motor (EMG) and electroencephalography seizure duration (EEG), heart rate (HR) and mean arterial pressure (MAP) values, and recovery times were recorded.


Minimum age: 18 Years. Maximum age: 60 Years. Gender(s): Both.


Inclusion Criteria:

- Study included 25 patients of American Society of Anesthesiologists (ASA) physical

status I-II aged between 18-60 years who were scheduled for ECT sessions under general anesthesia Exclusion Criteria:

- Pregnancy

- Cerebrovascular disease

- Epilepsy

- Unstable cardiovascular disease

- Chronic obstructive pulmonary disease; and

- Renal or hepatic failure

Locations and Contacts

Inonu Unıversity School of Medicine, Malatya 44100, Turkey
Additional Information

Starting date: March 2013
Last updated: July 22, 2013

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017