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Teriparatide for Improved Knee Prosthesis Fixation

Information source: University Hospital, Linkoeping
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Osteoarthritis of the Knee

Intervention: teriparatide (Drug)

Phase: Phase 2

Status: Completed

Sponsored by: University Hospital, Linkoeping


The investigators will study how well knee joint prostheses become fixed to the bone when patients get teriparatide, compared to placebo. Measurements will use high resolution 3D radiography (radiostereometry, RSA).

Clinical Details

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Primary outcome: Migration as measured by RSA maximal total point motion.


Minimum age: 60 Years. Maximum age: 80 Years. Gender(s): Both.


Inclusion Criteria:

- Osteoarthritis of the knee planned for prosthesis surgery

Exclusion Criteria:

- Poor health, drugs affecting bone metabolism.

Locations and Contacts

Motala hospital, Motala, Sweden
Additional Information

Starting date: February 2010
Last updated: June 17, 2013

Page last updated: August 20, 2015

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