Teriparatide for Improved Knee Prosthesis Fixation
Information source: University Hospital, Linkoeping
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Osteoarthritis of the Knee
Intervention: teriparatide (Drug)
Phase: Phase 2
Status: Completed
Sponsored by: University Hospital, Linkoeping
Summary
The investigators will study how well knee joint prostheses become fixed to the bone when
patients get teriparatide, compared to placebo. Measurements will use high resolution 3D
radiography (radiostereometry, RSA).
Clinical Details
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
Primary outcome: Migration as measured by RSA maximal total point motion.
Eligibility
Minimum age: 60 Years.
Maximum age: 80 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Osteoarthritis of the knee planned for prosthesis surgery
Exclusion Criteria:
- Poor health, drugs affecting bone metabolism.
Locations and Contacts
Motala hospital, Motala, Sweden
Additional Information
Starting date: February 2010
Last updated: June 17, 2013
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