DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more



The Use of L-Carnitine And CoQ10 Supplements In the Treatment of Cyclic Vomiting Syndrome (CVS)

Information source: Medical College of Wisconsin
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Cyclic Vomiting Syndrome

Phase: N/A

Status: Enrolling by invitation

Sponsored by: Medical College of Wisconsin

Official(s) and/or principal investigator(s):
B Li, MD, Principal Investigator, Affiliation: Medical College of Wiconsin

Summary

This is a study with the principle goal being to learn about the use of L-Carnitine and CoQ10, two vitamin supplements that are currently being used to treat Cyclic Vomiting Syndrome, largely initiated by parents. We want to learn how effective these supplements are compared to standard treatment, at what dose, and what onset of action in order to initiate future prospective study on these supplements.

Clinical Details

Official title: Co-Enzyme Q10, L-Carnitine and Amitriptyline Usage in Cyclic Vomiting Syndrome (CVS): A Research Study

Study design: Observational Model: Family-Based, Time Perspective: Prospective

Primary outcome: How two vitamin supplements are being used to treat cyclic vomiting syndrome

Secondary outcome: How effective these supplements appear to be compared to standard treatment

Eligibility

Minimum age: N/A. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- 3 discrete episodes of vomiting

- normal health between episodes

- stereotypical clinical pattern

- no abnormal test results to account for vomiting (see exclusion criteria)

Exclusion Criteria:

- abnormal UGI with small bowel follow-through revealing an anatomic anomaly,

inflammatory or obstructive

- Significantly abnormal endoscopic biopsies (moderate to severe esophagitis, H.

pylori)

- Abnormal abdominal ultrasound revealing hydronephrosis, cholelithiasis, pancreatitis

- Positive screening for endocrine disorder (diabetic ketoacidosis, Addison's)

- Positive screening for inborn errors of metabolism (hypoglycemia, lactic acidosis,

hyperammonemia, organic acidemia, amino aciduria, elevated beta-ALA, porphobilinogen)

Locations and Contacts

Children's Hospital of Wisconsin, Milwaukee, Wisconsin 53226, United States
Additional Information

Cyclic Vomiting Syndrome Association

Starting date: October 2007
Last updated: January 3, 2014

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017