DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Povidone Iodine and Cesarean Section Wound Infections

Information source: Assiut University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Wound Infections

Intervention: Povidone Iodine 10% vand cesarean section wound infections (Drug); Povidone Iodine 7.5% vand cesarean section wound infections (Drug)

Phase: Phase 3

Status: Completed

Sponsored by: Assiut University


The aim of this randomized clinical trial is to compare the efficiency of hand scrubbing by Povidone-Iodine solution 10% over 7. 5% concentration in decreasing post-cesarean section wound infections & compare side effects of both agents.

Clinical Details

Official title: Povidone Iodine 10% Versus 7.5% Hand Scrub and Cesarean Section Wound Infections: A Randomized Trial

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Primary outcome: The difference of incidence of surgical site infection between both groups

Secondary outcome: The difference in the side effects between both groups e.g. dermatitis

Detailed description: For centuries, hand washing with soap and water has been considered the main approach for personal hygiene. In the community, hand hygiene has been known to prevent infectious diseases and to decrease the burden of disease. Currently, hand hygiene is considered the most important measure for preventing the spread of pathogens in health-care settings. There are multiple agents used for surgical hand scrubbing as alcohol, chlorhexidine, iodine/iodophors, para-chloro-meta-xylenol & triclosan. Ideally, the optimum antiseptic used for scrub should have broad spectrum of activity, persistent effect & fast acting. Unfortunately most studies evaluating surgical scrub antiseptics have focused on measuring hand bacterial colony counts. No randomized clinical trials have evaluated the impact of surgical scrub choice on surgical site infection risk & proven its efficiency.


Minimum age: 18 Years. Maximum age: 40 Years. Gender(s): Female.


Inclusion Criteria:

- elective caesarian section (CS)

Exclusion Criteria:

- diabetes,

- immuno-compromised patients

Locations and Contacts

Women Health Hospital - Assiut university, Assiut 71111, Egypt
Additional Information

Starting date: January 2012
Last updated: October 3, 2012

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017