Combination of Psychosocial Intervention and Slow Prosecutions for the Treatment of Methamphetamine Abuse/Dependence

Condition(s) targeted: Amphetamine Abuse; Amphetamine Dependence; Methamphetamine Abuse; Methamphetamine Dependence

Intervention: Psychosocial intervention (Behavioral); Telephone reminding (Behavioral)

Phase: N/A

Status: Not yet recruiting

Sponsored by: National Taiwan University Hospital

Official(s) and/or principal investigator(s):
Yi-Ting Lin, M.D., Principal Investigator, Affiliation: Department of Psychiatry, National Taiwan University Hospital Yunlin Branch

Overall contact:
Yi-Ting Lin, M.D., Phone: +886-5-5323911, Ext: 7120, Email: p98421013@ntu.edut.tw

The hospital where this study will be conducted is responsible for the one-year contingency management treatment for methamphetamine drug offenders referred from the Yunlin District Prosecutors Office. Completing the one-year treatment is prerequisite for offenders to get slow prosecutions.

It is an open-label, parallel-group trial comparing the combination of psychosocial intervention and slow prosecutions with psychosocial intervention alone in treating subjects with methamphetamine dependence

Study Hypothesis

1. Psychosocial interventions in combination with slow prosecutions is more effective than psychosocial interventions alone to achieve abstinence for subjects with methamphetamine abuse/dependance.

2. Inclusion of telephone reminding before each visit will enhance the retention rate and abstinence rate.

Official title: Combination of Psychosocial Intervention and Slow Prosecutions for the Treatment of Methamphetamine Abuse/Dependence

Study design: Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Primary outcome: Endpoint abstinence rate

Secondary outcome:

Retention rate

Length of retention

The longest period of abstinence

Minimum age: 18 Years. Maximum age: 65 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- DSM-IV-TR criteria for amphetamine/methamphetamine abuse or dependence

- 18 - 65 years old

- For TSTSU-N and TSTSU-T arms: methamphetamine offenders referred by the Yunlin

District Prosecutors Office

- For OPD arm: psychiatric outpatients referred from the psychiatry clinics in National

Taiwan University Hospital, Yunlin Branch

Exclusion Criteria:

- Concurrent use of other illicit substances

- Co-morbidity with major psychotic disorders (schizophrenia, schizoaffective disorder,

other psychotic disorder), mental retardation, acute episodes of major depressive disorder or bipolar affective disorder) or serious personality disorders.

Yi-Ting Lin, M.D., Phone: +886-5-5323911, Ext: 7120, Email: p98421013@ntu.edut.tw

National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan; Not yet recruiting
Yi-Ting Lin, M.D., Phone: +886-5-5323911, Ext: 7120, Email: p98421013@ntu.edu.tw
Yi-Ting Lin, M.D., Principal Investigator
Li-Ren Chang, M.D., Sub-Investigator

Starting date: January 2011
Last updated: January 6, 2011