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Zyvox (Linezolid) - Thrombocytopenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Thrombocytopenia (22)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Zyvox (Linezolid) where reactions include thrombocytopenia. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Zyvox side effects in 82 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-16

Patient: 82 year old female

Reactions: Anaemia, Neutropenia, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Gentamicin
    Dosage: 420 mg, 1x/day
    Indication: Staphylococcal Sepsis
    Start date: 2012-04-14
    End date: 2012-04-16

Calciparine
    Dosage: 5000 iu, 2x/day
    Indication: Thrombosis Prophylaxis
    Start date: 2012-04-14
    End date: 2012-04-25

Zyvox
    Dosage: 600 mg, 2x/day
    Indication: Staphylococcal Sepsis
    Start date: 2012-04-16
    End date: 2012-04-22

Orbenin CAP
    Dosage: 2 g, 4x/day
    Indication: Staphylococcal Sepsis
    Start date: 2012-04-14
    End date: 2012-04-16

Other drugs received by patient: Atacand; Depakene; Previscan; Cordarone; Levothyroxine Sodium; Pantoprazole Sodium; Lercanidipine; Prednisone TAB; Keppra



Possible Zyvox side effects in 65 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-14

Patient: 65 year old male, weighing 66.0 kg (145.2 pounds)

Reactions: Weight Decreased, Vomiting, Mycobacterium Chelonae Infection, Hyperkalaemia, Hypercreatininaemia, Rectal Haemorrhage, Reticulocyte Count Decreased, Diarrhoea, RED Blood Cell Count Decreased, Megakaryocytes Abnormal, Neutropenia, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisone TAB
    Dosage: 3 mg, daily
    Administration route: Oral
    Indication: Juvenile Arthritis

Zyvox
    Dosage: 7.8 mg/l, unknown
    Start date: 2012-06-28

Methotrexate
    Dosage: 20 mg, weekly
    Administration route: Oral
    Indication: Juvenile Arthritis

Zyvox
    Dosage: 600 mg, 2x/day
    Start date: 2012-05-31
    End date: 2012-06-26

Ketoprofen
    Dosage: 100-300 mg, daily
    Administration route: Oral
    Indication: Juvenile Arthritis

Clarithromycin
    Dosage: 500 mg, 2x/day
    Start date: 2012-05-31
    End date: 2012-06-26

Other drugs received by patient: Sertraline; Bisoprolol; Metformin; Tetrazepam; Pantoprazole; Aspegic 1000



Possible Zyvox side effects in 52 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-14

Patient: 52 year old female

Reactions: Anaemia, Condition Aggravated, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ofloxacin
    Dosage: unk
    Administration route: Oral
    Indication: Infection
    Start date: 2012-06-04
    End date: 2012-07-17

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Indication: Infection
    Start date: 2012-06-04
    End date: 2012-07-14

Other drugs received by patient: Alprazolam; Nexium; Zolpidem; Sodium Bicarbonate; Humalog; Lantus; Prograf; Cell Cept; Prednisolone; Singulair



Possible Zyvox side effects in 92 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-07

Patient: 92 year old male

Reactions: Anaemia, Thrombocytopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient: Acetaminophen; Betamethasone; Nexium; Ceftriaxone; Fluconazole; Digoxin; Tazobactam; Noxafil; Furosemide



Possible Zyvox side effects in 65 year old male

Reported by a physician from Ireland on 2012-08-01

Patient: 65 year old male, weighing 87.0 kg (191.4 pounds)

Reactions: General Physical Condition Abnormal, Diarrhoea, Nephropathy Toxic, Pancytopenia, Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zyvox
    Dosage: unk
    Administration route: Oral
    Indication: Staphylococcal Infection
    Start date: 2011-02-01
    End date: 2011-04-27

Zyvox
    Indication: Diabetic Foot

Other drugs received by patient: Perindopril Erbumine; Atenolol; Tiotropium; Plavix; Gabapentin; Levemir; Fluticasone Propionate / Salmeterol



Possible Zyvox side effects in 92 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-31

Patient: 92 year old male

Reactions: Anaemia, Thrombocytopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient: Betamethasone; Fluconazole; Nexium; Tazobactam; Furosemide; Acetaminophen; Ceftriaxone; Digoxin; Noxafil



Possible Zyvox side effects in

Reported by a pharmacist from United States on 2012-06-28

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Zyvox



Possible Zyvox side effects in 20 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-14

Patient: 20 year old male

Reactions: Cytolytic Hepatitis, Cholestasis, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox
    Dosage: unk
    Indication: Cellulitis
    Start date: 2012-04-27
    End date: 2012-05-02

Tazobactam
    Dosage: 4 g, 3x/day
    Indication: Cellulitis
    Start date: 2012-04-11
    End date: 2012-04-27



Possible Zyvox side effects in 65 year old male

Reported by a physician from Ireland on 2012-06-04

Patient: 65 year old male

Reactions: General Physical Condition Abnormal, Nephropathy Toxic, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox



Possible Zyvox side effects in 22 year old male

Reported by a physician from United States on 2012-04-27

Patient: 22 year old male, weighing 91.9 kg (202.2 pounds)

Reactions: White Blood Cell Count Decreased, Retinal Haemorrhage, NO Therapeutic Response, Visual Impairment, Condition Aggravated, Neutrophil Count Decreased, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: 1000 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-12-15
    End date: 2012-03-17

Mitoxantrone Hydrochloride
    Dosage: 12 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-12-15

Zyvox
    Indication: Product Used FOR Unknown Indication

Velcade
    Dosage: iv bolus
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-12-15
    End date: 2012-03-20

Etoposide
    Dosage: 100 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-12-15
    End date: 2012-03-17

Daunorubicin HCL
    Dosage: 50 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-12-15

Other drugs received by patient: Vancomycin; Voriconazole; Flagyl; Micafungin; Acyclovir; Neupogen; Zosyn; Daptomycin



Possible Zyvox side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-11

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Zyvox



Possible Zyvox side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-22

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Zyvox



Possible Zyvox side effects in 51 year old female

Reported by a health professional (non-physician/pharmacist) from Malaysia on 2012-02-17

Patient: 51 year old female

Reactions: Thrombocytopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Zyvox



Possible Zyvox side effects in 85 year old female

Reported by a physician from Switzerland on 2012-02-03

Patient: 85 year old female

Reactions: Anaemia, Melaena, Thrombocytopenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Indication: Liver Abscess
    Start date: 2011-12-22
    End date: 2012-01-12

Aspirin
    Dosage: 100 mg, 1x/day
    Indication: Ischaemic Cardiomyopathy
    End date: 2012-01-13

Ciprofloxacin Hydrochloride
    Dosage: 500 mg, 2x/day
    Administration route: Oral
    Indication: Liver Abscess
    Start date: 2011-12-22
    End date: 2012-01-12

Other drugs received by patient: Metoprolol Tartrate and Hydrochlorothiazide; Torasemide; Amlodipine



Possible Zyvox side effects in 9 year old male

Reported by a physician from Chile on 2012-01-17

Patient: 9 year old male

Reactions: Haemorrhage, Thrombocytopenia

Drug(s) suspected as cause:
Zyvox



Possible Zyvox side effects in 66 year old female

Reported by a lawyer from United States on 2012-01-11

Patient: 66 year old female

Reactions: Unresponsive To Stimuli, Saliva Discolouration, Accidental Overdose, Electroencephalogram Abnormal, Multiple Injuries, Pneumonia Staphylococcal, Staphylococcal Bacteraemia, Cold Sweat, White Blood Cell Count Increased, Pneumonia, Malnutrition, Anaemia, Hypoxic-Ischaemic Encephalopathy, Staphylococcal Infection, Mobility Decreased, Atelectasis, Rhabdomyolysis, Tracheal Stenosis, Pain, Hypokalaemia, Cardio-Respiratory Arrest, Overdose, Aspiration, Thrombocytopenia, Gastrooesophageal Reflux Disease, Acute Respiratory Failure, Renal Failure Acute, Blood Glucose Increased, Deformity, Anxiety, Cardiac Arrest, Asthenia, Lung Infiltration, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization, disablity

Drug(s) suspected as cause:
Fentanyl
    Dosage: tder ; 3 patches;tder
    Indication: Oropharyngeal Blistering
    Start date: 2010-08-03

Fentanyl
    Dosage: tder ; 3 patches;tder
    Indication: Oropharyngeal Blistering
    End date: 2010-08-04

Zyvox

Oxycodone HCL



Possible Zyvox side effects in 83 year old female

Reported by a physician from France on 2011-11-25

Patient: 83 year old female

Reactions: Refractory Anaemia, Renal Failure, Lactic Acidosis, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient: Rabeprazole Sodium; Previscan; Lexomil; Cordarone; Bisoprolol Fumarate; Acetaminophen; Orgaran; Crestor



Possible Zyvox side effects in female

Reported by a physician from France on 2011-11-18

Patient: female

Reactions: Renal Failure, Refractory Anaemia, Lactic Acidosis, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zyvox



Possible Zyvox side effects in 70 year old male

Reported by a pharmacist from Spain on 2011-10-31

Patient: 70 year old male

Reactions: Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Enoxaparin Sodium
    Dosage: 40 mg, unk
    Start date: 2011-06-12
    End date: 2011-06-17

Zyvox
    Dosage: 1200 mg, 1x/day
    Start date: 2011-06-10
    End date: 2011-06-27

Zyvox
    Dosage: 1200 mg, 1x/day
    Start date: 2011-05-26
    End date: 2011-06-01

Enoxaparin Sodium
    Dosage: 160 mg, 1x/day
    Start date: 2011-05-27
    End date: 2011-05-29

Other drugs received by patient: Aspirin; Sintrom



Possible Zyvox side effects in female

Reported by a pharmacist from United States on 2011-10-18

Patient: female, weighing 98.8 kg (217.4 pounds)

Reactions: Hypotension, Anaemia, Neutropenia, Haemolytic Anaemia, Thrombocytopenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient: Zosyn



Possible Zyvox side effects in 72 year old male

Reported by a physician from Sweden on 2011-10-06

Patient: 72 year old male

Reactions: Diarrhoea, Anaemia, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox
    Dosage: 1.2 g, 1x/day
    Administration route: Oral
    Indication: Sternitis
    Start date: 2011-03-01
    End date: 2011-03-21

Zyvox
    Indication: Mediastinitis

Other drugs received by patient: Potassium Chloride; Furosemide; Simvastatin; Behepan; Oxycontin; Novomix; Oxycodone HCL; Atacand; Citalopram; Mycostatin; Bisoprolol Fumarate; Spironolactone; Acetaminophen; Aspirin



Possible Zyvox side effects in 65 year old female

Reported by a pharmacist from United States on 2011-10-05

Patient: 65 year old female, weighing 90.5 kg (199.1 pounds)

Reactions: Localised Infection, Contusion, Anaemia, Thrombocytopenia, Wound Secretion

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox

Other drugs received by patient: Ethacrynic Acid; Fortaz; Flexeril; Omeprazole; Aspirin; Zocor; Phenergan HCL; Gabapentin; Vicodin

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