This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Zyvox (Linezolid) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (563)
Death (99)
Life Threatening Events (41)
Disability (19)
Reports by Reaction Type
Nausea (36),
Drug Interaction (31),
Vomiting (31),
Platelet Count Decreased (29),
Diarrhoea (27),
Death (25),
Renal Failure Acute (25),
Hyponatraemia (25),
Anaemia (24),
Serotonin Syndrome (23),
Thrombocytopenia (22),
Malaise (21)
Below are a few examples of reports where side effects / adverse reactions may be related to Zyvox (Linezolid). For a complete list or a specific selection of reports, please use the links above.
Possible Zyvox side effects in
Reported by a consumer/non-health professional from Japan on 2012-08-27
Patient:
Reactions: NO Adverse Event
Drug(s) suspected as cause:
Betamethasone Valerate
Dosage: unk
Start date: 2012-04-10
End date: 2012-05-07
Flagyl
Dosage: 1000 mg, unk
Administration route: Oral
Indication: Pseudomembranous Colitis
Start date: 2012-04-03
End date: 2012-04-04
Flagyl
Dosage: 1000 unk, unk
Administration route: Oral
Start date: 2012-04-29
End date: 2012-05-12
Vancomycin HCL
Dosage: 1 mg, unk
Start date: 2012-04-16
End date: 2012-04-29
Zyvox
Dosage: 1200 mg, unk
Start date: 2012-05-02
End date: 2012-05-15
Other drugs received by patient: Dorner; Aldactone; Dorner; Lebenin; Olopatadine HCL; Plavix; Pydoxal; Clobetasol Propionate; Hirudoid; Aspara K; Yunasupin; Vancomycin HCL; Gentamicin Sulfate; Nizoral; Hirudoid; Prednisolone; Plavix; Lebenin; Aspara K; Trichlormethiazide; Myser (Difluprednate); Myser (Difluprednate); Methylprednisolone Sodium Succinate
Possible Zyvox side effects in 68 year old male
Reported by a physician from Japan on 2012-08-27
Patient: 68 year old male, weighing 37.0 kg (81.4 pounds)
Reactions: Pneumonia, Hepatic Function Abnormal, Platelet Count Decreased, Hyponatraemia
Adverse event resulted in: death
Drug(s) suspected as cause:
Zyvox
Dosage: 600 mg, 2x/day
Indication: Pneumonia Staphylococcal
Start date: 2012-05-07
End date: 2012-05-19
Zyvox
Dosage: 600 mg, 2x/day
Start date: 2012-05-26
End date: 2012-06-01
Other drugs received by patient: Meropenem; Teicoplanin; Picillibacta
Possible Zyvox side effects in 65 year old female
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-08-27
Patient: 65 year old female, weighing 64.0 kg (140.8 pounds)
Reactions: Drug Interaction, Renal Failure Acute
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Amiodarone HCL
Dosage: 200 mg, qd
Administration route: Oral
Indication: Atrial Fibrillation
Start date: 2008-09-01
End date: 2008-10-10
Ramipril
Dosage: 2.5 mg, qd
Administration route: Oral
Indication: Hypertension
Start date: 2008-09-01
End date: 2008-10-09
Zyvox
Dosage: unk
Start date: 2008-10-25
End date: 2009-01-27
Zyvox
Dosage: 600 mg, bid
Administration route: Oral
Indication: Intervertebral Discitis
Start date: 2008-09-22
End date: 2008-10-09
Other drugs received by patient possibly interacting with the suspect drug:
Spironolactone
Dosage: 100 mg, qd
Administration route: Oral
Indication: Hypertension
Start date: 2008-09-01
End date: 2008-10-09
Torsemide
Dosage: 10 mg, bid
Administration route: Oral
Indication: Hypertension
Start date: 2008-07-29
Xipamide
Dosage: 10 mg, qd
Administration route: Oral
Indication: Hypertension
Start date: 2008-07-29
End date: 2008-10-08
Other drugs received by patient: Acetaminophen; Enoxaparin Sodium; Simvastatin; Amitriptyline HCL; Novalgin; Omeprazole; Oxycodone HCL; Metoprolol Tartrate; Digitoxin TAB
Possible Zyvox side effects in 90 year old female
Reported by a pharmacist from Japan on 2012-08-24
Patient: 90 year old female
Reactions: Hyponatraemia
Drug(s) suspected as cause:
Zyvox
Other drugs received by patient: Rocephin; Lasix; Soldactone; Lasix; Physio; Physio; Thiospen; Amigrand; Hanp; Vitamedin Intravenous; Elaspol; Soldactone; Intralipid 10%; Solita-T 3G; Lactec; Ascorbic Acid
Possible Zyvox side effects in 84 year old male
Reported by a pharmacist from Japan on 2012-08-23
Patient: 84 year old male
Reactions: Disseminated Intravascular Coagulation, Platelet Count Decreased
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Famotidine
Dosage: 40 mg, 1x/day
Indication: Gastric Ulcer Haemorrhage
Start date: 2012-07-18
End date: 2012-07-30
Zyvox
Dosage: 1200 mg, 1x/day
Indication: Pneumonia
Start date: 2012-07-17
End date: 2012-07-27
Other drugs received by patient: Lasix; Methylprednisolone Sodium Succinate; Bisolvon
Possible Zyvox side effects in 22 month old female
Reported by a physician from United States on 2012-08-23
Patient: 22 month old female, weighing 10.0 kg (22.0 pounds)
Reactions: Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in male
Reported by a pharmacist from United States on 2012-08-23
Patient: male
Reactions: Drug Withdrawal Syndrome
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in 54 year old male
Reported by a consumer/non-health professional from United States on 2012-08-21
Patient: 54 year old male, weighing 77.1 kg (169.6 pounds)
Reactions: Drug Ineffective
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in 77 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20
Patient: 77 year old female
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in 15 year old male
Reported by a physician from United States on 2012-08-17
Patient: 15 year old male, weighing 47.0 kg (103.4 pounds)
Reactions: Blood Bilirubin Increased, Agitation, Insomnia, Drug Interaction, Faeces Discoloured
Drug(s) suspected as cause:
Zyvox
Other drugs received by patient possibly interacting with the suspect drug:
Sinemet
Dosage: unk
Indication: Quadriplegia
End date: 2012-07-01
Sinemet
Dosage: unk
Start date: 2012-07-01
Other drugs received by patient: Vancomycin; Baclofen; Tylenol; Albuterol
Possible Zyvox side effects in
Reported by a physician from Japan on 2012-08-17
Patient:
Reactions: Ileus
Adverse event resulted in: death
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in 77 year old female
Reported by a physician from United States on 2012-08-16
Patient: 77 year old female, weighing 79.4 kg (174.6 pounds)
Reactions: Movement Disorder, Oral Mucosal Blistering, Drug Ineffective, Mouth Ulceration, Oropharyngeal Pain, Rash, Limb Discomfort, Dyspepsia, Chest Pain, Skin Odour Abnormal
Drug(s) suspected as cause:
Zyvox
Other drugs received by patient: Lipitor
Possible Zyvox side effects in 82 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-16
Patient: 82 year old female
Reactions: Anaemia, Neutropenia, Thrombocytopenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Calciparine
Dosage: 5000 iu, 2x/day
Indication: Thrombosis Prophylaxis
Start date: 2012-04-14
End date: 2012-04-25
Gentamicin
Dosage: 420 mg, 1x/day
Indication: Staphylococcal Sepsis
Start date: 2012-04-14
End date: 2012-04-16
Orbenin CAP
Dosage: 2 g, 4x/day
Indication: Staphylococcal Sepsis
Start date: 2012-04-14
End date: 2012-04-16
Zyvox
Dosage: 600 mg, 2x/day
Indication: Staphylococcal Sepsis
Start date: 2012-04-16
End date: 2012-04-22
Other drugs received by patient: Atacand; Depakene; Previscan; Cordarone; Levothyroxine Sodium; Pantoprazole Sodium; Lercanidipine; Prednisone TAB; Keppra
Possible Zyvox side effects in 11 year old male
Reported by a consumer/non-health professional from United States on 2012-08-15
Patient: 11 year old male
Reactions: Glossodynia
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in 70 year old male
Reported by a pharmacist from Japan on 2012-08-15
Patient: 70 year old male
Reactions: Haemodialysis
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in 87 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-14
Patient: 87 year old female
Reactions: Agitation, Confusional State
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Tazobactam
Dosage: unk
Indication: Escherichia Infection
Start date: 2012-07-17
End date: 2012-07-21
Zyvox
Dosage: unk
Indication: Escherichia Infection
Start date: 2012-07-17
End date: 2012-07-21
Other drugs received by patient: Augmentin '500'; Rocephin
Possible Zyvox side effects in 52 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-14
Patient: 52 year old female
Reactions: Anaemia, Condition Aggravated, Thrombocytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ofloxacin
Dosage: unk
Administration route: Oral
Indication: Infection
Start date: 2012-06-04
End date: 2012-07-17
Zyvox
Dosage: 600 mg, 2x/day
Administration route: Oral
Indication: Infection
Start date: 2012-06-04
End date: 2012-07-14
Other drugs received by patient: Alprazolam; Nexium; Zolpidem; Sodium Bicarbonate; Humalog; Lantus; Prograf; Cell Cept; Prednisolone; Singulair
Possible Zyvox side effects in 65 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-14
Patient: 65 year old male, weighing 66.0 kg (145.2 pounds)
Reactions: Weight Decreased, Vomiting, Mycobacterium Chelonae Infection, Hyperkalaemia, Hypercreatininaemia, Rectal Haemorrhage, Reticulocyte Count Decreased, Diarrhoea, RED Blood Cell Count Decreased, Megakaryocytes Abnormal, Neutropenia, Thrombocytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Clarithromycin
Dosage: 500 mg, 2x/day
Start date: 2012-05-31
End date: 2012-06-26
Ketoprofen
Dosage: 100-300 mg, daily
Administration route: Oral
Indication: Juvenile Arthritis
Methotrexate
Dosage: 20 mg, weekly
Administration route: Oral
Indication: Juvenile Arthritis
Prednisone TAB
Dosage: 3 mg, daily
Administration route: Oral
Indication: Juvenile Arthritis
Zyvox
Dosage: 7.8 mg/l, unknown
Start date: 2012-06-28
Zyvox
Dosage: 600 mg, 2x/day
Start date: 2012-05-31
End date: 2012-06-26
Other drugs received by patient: Sertraline; Bisoprolol; Metformin; Tetrazepam; Pantoprazole; Aspegic 1000
Possible Zyvox side effects in 77 year old female
Reported by a consumer/non-health professional from United States on 2012-08-13
Patient: 77 year old female, weighing 79.4 kg (174.6 pounds)
Reactions: Movement Disorder, Oral Mucosal Blistering, Drug Ineffective, Mouth Ulceration, Oropharyngeal Pain, Rash, Limb Discomfort, Dyspepsia, Skin Odour Abnormal, Chest Pain
Drug(s) suspected as cause:
Zyvox
Other drugs received by patient: Lipitor
Possible Zyvox side effects in 45 year old female
Reported by a consumer/non-health professional from United States on 2012-08-13
Patient: 45 year old female, weighing 51.2 kg (112.7 pounds)
Reactions: Rash
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-13
Patient: female
Reactions: Malaise, Infection
Drug(s) suspected as cause:
Lipitor
Dosage: unk
Zoloft
Dosage: unk
Zyvox
Dosage: unk
Possible Zyvox side effects in
Reported by a physician from Japan on 2012-08-13
Patient:
Reactions: Platelet Count Decreased, Erythema Multiforme
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Betamethasone
Dosage: unk mg, unk
Start date: 2012-04-10
End date: 2012-05-07
Flagyl
Dosage: 1000 mg, unk
Start date: 2012-04-29
End date: 2012-05-12
Flagyl
Dosage: 1000 mg, unk
Administration route: Oral
Indication: Pseudomembranous Colitis
Start date: 2012-04-03
End date: 2012-04-04
Vancomycin Hydrochloride
Dosage: 1 g, unk
Start date: 2012-04-16
End date: 2012-04-29
Zyvox
Dosage: 1200 mg, unk
Other drugs received by patient: Lebenin; Yunasupin; Gentamicin Sulfate; Dorner; Lebenin; Pydoxal; Nizoral; Methylprednisolone Sodium Succinate; Targocid; Dorner; Myser (Difluprednate); Olopatadine HCL; Prednisolone; Nicoranta; Plavix; Trichlormethiazide; Vancomycin Hydrochloride; Aspara K; Myser (Difluprednate); Plavix; Aldactone; Aspara K
Possible Zyvox side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-10
Patient: female
Reactions: Viral Infection
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in
Reported by a physician from United States on 2012-08-09
Patient:
Reactions: Psychiatric Symptom, Depression
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in 24 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-08
Patient: 24 year old male
Reactions: Burning Sensation, Rash Generalised, Alopecia
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-07
Patient: female
Reactions: Diarrhoea
Drug(s) suspected as cause:
Zyvox
Other drugs received by patient: Acidophilus
Possible Zyvox side effects in 65 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-07
Patient: 65 year old male, weighing 66.0 kg (145.2 pounds)
Reactions: Weight Decreased, Vomiting, Pancytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Clarithromycin
Dosage: 500 mg, 2x/day
Administration route: Oral
Start date: 2012-05-31
End date: 2012-06-26
Zyvox
Dosage: 600 mg, 2x/day
Administration route: Oral
Start date: 2012-05-31
End date: 2012-06-26
Other drugs received by patient: Prednisone TAB; Ketoprofen; Sertraline; Aspegic 1000; Methotrexate; Tetrazepam; Bisoprolol; Metformin; Pantoprazole
Possible Zyvox side effects in 78 year old male
Reported by a pharmacist from Japan on 2012-08-07
Patient: 78 year old male
Reactions: Angiopathy
Drug(s) suspected as cause:
Zyvox
Possible Zyvox side effects in 92 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-07
Patient: 92 year old male
Reactions: Anaemia, Thrombocytopenia
Adverse event resulted in: death
Drug(s) suspected as cause:
Zyvox
Other drugs received by patient: Acetaminophen; Betamethasone; Nexium; Ceftriaxone; Fluconazole; Digoxin; Tazobactam; Noxafil; Furosemide
Possible Zyvox side effects in 46 year old male
Reported by a physician from United States on 2012-08-06
Patient: 46 year old male
Reactions: Anxiety, Malaise, Nausea, Visual Impairment, Vision Blurred, Dizziness, Feeling Abnormal
Drug(s) suspected as cause:
Zyvox
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