Zometa (Zoledronic Acid) - Death - Suspected Cause - Side Effect Reports

Possible Zometa side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-27

Patient: male, weighing 60.0 kg (132.0 pounds)

Reactions: Malaise, Bronchopneumonia, Septic Shock, Immunosuppression, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zometa

Other drugs received by patient possibly interacting with the suspect drug:
Remicade
    Dosage: 5 mg/kg, 1/8 weeks
    Indication: Crohn's Disease
    Start date: 2011-01-11

Other drugs received by patient: Azathioprine Sodium; Prednisolone

Possible Zometa side effects in female

Reported by a physician from France on 2012-08-27

Patient: female

Reactions: Confusional State, Acute Pulmonary Oedema, Agitation, Renal Failure Acute

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Acetaminophen
    Administration route: Oral
    End date: 2012-07-26

Aspirin
    Administration route: Oral

Atorvastatin
    Administration route: Oral

Bisoprolol Fumarate
    Dosage: 2.5 mg in the morning and 1.25 mg in the evening
    Administration route: Oral
    End date: 2012-07-27

Cymbalta
    Administration route: Oral
    End date: 2012-07-26

Duragesic-100
    End date: 2012-07-26

Lercanidipine
    Administration route: Oral
    End date: 2012-07-26

Lyrica
    Administration route: Oral
    End date: 2012-07-26

Nexium
    Administration route: Oral

Nitroglycerin
    End date: 2012-07-26

Plavix
    Administration route: Oral

Ramipril
    Administration route: Oral
    End date: 2012-07-26

Zometa
    Start date: 2012-07-19
    End date: 2012-07-19

Possible Zometa side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-27

Patient: female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa

Possible Zometa side effects in 61 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-27

Patient: 61 year old female

Reactions: Agitation, Confusional State, Acute Pulmonary Oedema, Metastatic Pain, Hypercalcaemia, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Acetaminophen
    Dosage: 1 g, 1x/day
    Administration route: Oral
    End date: 2012-07-26

Aspirin
    Dosage: 75 mg, 1x/day
    Administration route: Oral

Atorvastatin
    Dosage: 10 mg, 1x/day
    Administration route: Oral

Bisoprolol Fumarate
    Dosage: 3.75 mg, 1x/day
    Administration route: Oral
    End date: 2012-07-27

Cymbalta
    Dosage: 60 mg, 1x/day
    Administration route: Oral
    End date: 2012-07-26

Duragesic-100
    Dosage: 50 mg, 1x/day
    End date: 2012-07-26

Lercanidipine
    Dosage: 10 mg, 1x/day
    Administration route: Oral
    End date: 2012-07-26

Lyrica
    Dosage: 75 mg, 2x/day
    Administration route: Oral
    End date: 2012-07-26

Nexium
    Dosage: 20 mg, 1x/day
    Administration route: Oral

Nitroglycerin
    Dosage: 5 mg, 1x/day
    End date: 2012-07-26

Plavix
    Dosage: 75 mg, 1x/day
    Administration route: Oral

Ramipril
    Dosage: 10 mg, 1x/day
    Administration route: Oral
    End date: 2012-07-26

Zometa
    Dosage: 4 mg, single
    Indication: Hypercalcaemia
    Start date: 2012-07-19
    End date: 2012-07-19

Possible Zometa side effects in 61 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-27

Patient: 61 year old female

Reactions: Confusional State, Agitation, Renal Failure Acute

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Acetaminophen
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-07-26

Aspirin
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Atorvastatin
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Bisoprolol Fumarate
    Dosage: 2.5-0-1.25
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-07-27

Cymbalta
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-07-26

Duragesic-100
    Indication: Product Used FOR Unknown Indication
    End date: 2012-07-26

Lercanidipine
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-07-26

Lyrica
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-07-26

Nexium
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Nitroglycerin
    Indication: Product Used FOR Unknown Indication
    End date: 2012-07-27

Plavix
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Ramipril
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-07-26

Zometa
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-07-19
    End date: 2012-07-19

Possible Zometa side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-27

Patient: female

Reactions: Tooth Loss, Fractured Sacrum, Diabetes Mellitus, Tricuspid Valve Incompetence, Chronic Obstructive Pulmonary Disease, Cerebral Ventricle Dilatation, Cardiac Disorder, Cardiomegaly, Arteriosclerosis, Back Pain, Pancytopenia, Coronary Artery Disease, Osteopenia, Respiratory Tract Congestion, Rhinitis Allergic, Intervertebral Disc Space Narrowing, Sleep Disorder, Swelling, Acrochordon, Hypoventilation, Exposed Bone in JAW, Osteoporosis, Mental Status Changes, Multiple Myeloma, Oroantral Fistula, Hypercholesterolaemia, Anhedonia, Chest Pain, Obesity, Bone Disorder, Injury, Exostosis, Cataract, Dyspnoea, Diastolic Dysfunction, Carotid Artery Stenosis, Syncope, Impaired Healing, Mitral Valve Incompetence, Sinus Disorder, Hypothyroidism, Aortic Dilatation, Hypogammaglobulinaemia, Disability, Weight Decreased, Dermoid Cyst, Gastrointestinal Haemorrhage, Goitre, Urinary Incontinence, Pericardial Effusion, Cerebral Ischaemia, Proteinuria, Pathological Fracture, Aneurysm, Cough, Intervertebral Disc Protrusion, Pneumonia, Hiatus Hernia, Aortic Calcification, Anaemia, Eating Disorder, Convulsion, Chondrocalcinosis, Colitis, Mastication Disorder, Impaired Gastric Emptying, Rash Maculo-Papular, Neuralgia, Spinal Column Stenosis, Atelectasis, Pain, Gastritis, Myalgia, Death, Neuropathy Peripheral, Intervertebral Disc Degeneration, Bone Marrow Failure, Hair Follicle Tumour Benign, Cholecystitis, Sinusitis, Lymphoedema, Urinary Tract Infection, Cerebral Atrophy, Osteolysis, Renal Failure Chronic, Anxiety, Hyperlipidaemia, Osteoarthritis, Gastrointestinal Pain, Renal Impairment, Respiratory Failure, Diarrhoea, Osteonecrosis of JAW, Diabetic Retinopathy, Bone Neoplasm, Spinal Osteoarthritis, Bronchitis, Hypertension, Deep Vein Thrombosis, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Aredia
    Dosage: 90 mg, qmo
    Indication: Multiple Myeloma
    Start date: 2001-01-01
    End date: 2007-08-01

Zometa
    Dosage: 4 mg, qmo
    Start date: 2001-01-01
    End date: 2007-08-01

Other drugs received by patient: Augmentin '125'; Vitamin E; Lisinopril; Steroids NOS; Aspirin; Darvocet-N 50; Aspirin; Amlodipine; Acetaminophen; Colestid; Vicodin; Ativan; Megace; Reglan; Chlorpromazine HCL; Prednisone TAB; Decadron Phosphate; Lantus; Aranesp; Norco; Procrit; Velcade; Alavert; Melphalan Hydrochloride; Glycolax; Avandia; Actos; Insulin; Accupril; Heparin Sodium; Starlix; Lexapro; Warfarin Sodium; Nexium; Humalog; Timentin; Cardizem; Zocor; Calcium Carbonate; Esomeprazole Magnesium; Chemotherapeutics; Keppra; Levetiracetam; Tylenol

Possible Zometa side effects in female

Reported by a physician from United States on 2012-08-27

Patient: female, weighing 72.6 kg (159.6 pounds)

Reactions: Haemoptysis, Lung Cancer Metastatic, Pulmonary Embolism, Pneumothorax

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zometa

Other drugs received by patient: Carbo Medicinalis; Lavsol

Possible Zometa side effects in male

Reported by a consumer/non-health professional from Netherlands on 2012-08-27

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa
    Dosage: 4mg/100ml , once per 28 days
    Start date: 2012-07-17

Zometa
    Dosage: 4mg/100ml , once per 28 days
    Start date: 2012-01-12

Zometa
    Dosage: 4mg/100ml , once per 28 days
    Indication: Prostate Cancer Metastatic

Zometa
    Dosage: 4mg/100ml , once per 28 days
    Start date: 2012-06-19

Possible Zometa side effects in female

Reported by a physician from United States on 2012-08-24

Patient: female

Reactions: Tooth Loss, Tachycardia, Diverticulitis, Oral Cavity Fistula, Coma, Paralysis, Chronic Obstructive Pulmonary Disease, Oesophagitis, Gallbladder Disorder, Hypotension, Pseudomonas Infection, Coronary Artery Disease, Small Intestinal Obstruction, Emotional Distress, Diverticulum, Swelling, Exposed Bone in JAW, Metastases To Lymph Nodes, Gastric Ulcer, Abdominal Pain Upper, Ventricular Hypertrophy, Aortic Arteriosclerosis, Bone Disorder, Vomiting, Cataract, Lung Neoplasm, Arrhythmia, Syncope, Physical Disability, Gastrointestinal Haemorrhage, Osteomyelitis, Proteinuria, Tenderness, Radiculopathy, Laryngotracheal Oedema, Dysphagia, Hiatus Hernia, Cellulitis, Anaemia, Subclavian Artery Stenosis, Adenomyosis, Cholelithiasis, Iliac Artery Stenosis, Fistula Discharge, Adenoma Benign, Purulent Discharge, Atelectasis, Tooth Abscess, Pain, Central Nervous System Lesion, Hypokalaemia, Gastritis, Partial Seizures, Dyspnoea Exertional, Fatigue, Intervertebral Disc Degeneration, Dizziness, Pharyngitis, Pain in JAW, Swelling Face, Peripheral Vascular Disorder, Urinary Tract Infection, Atrial Fibrillation, Cholecystitis Chronic, Cerebrovascular Accident, Deformity, Hypercalcaemia, Anxiety, Hyperlipidaemia, Renal Failure, Diarrhoea, Osteonecrosis of JAW, Vertigo, Peripheral Arterial Occlusive Disease, Gingival Infection, Hypertension, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aredia

Fosamax

Pamidronate Disodium

Zometa

Other drugs received by patient: Dyazide; Tobramycin; Pletal; Plavix; Hydrochlorothiazide; Letrozole; Ciprofloxacin HCL; Aspirin; Lisinopril; Potassium; Clonidine; Ambien; Pentoxifylline; Niacin; Femara; Procrit; Magnesium; Vitamin TAB; Levaquin; Norvasc; Simvastatin; Quinine Sulfate; Lipitor; Vicodin

Possible Zometa side effects in female

Reported by a physician from Canada on 2012-08-24

Patient: female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa

Other drugs received by patient: Chemotherapeutics

Possible Zometa side effects in male

Reported by a physician from United States on 2012-08-24

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa

Possible Zometa side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-24

Patient: female

Reactions: Agitation, Confusional State, Renal Failure Acute

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Acetaminophen
    Administration route: Oral
    End date: 2012-07-26

Aspirin
    Administration route: Oral

Atorvastatin
    Administration route: Oral

Bisoprolol Fumarate
    Administration route: Oral
    End date: 2012-07-27

Cymbalta
    Administration route: Oral
    End date: 2012-07-26

Duragesic-100
    End date: 2012-07-26

Lercanidipine
    Administration route: Oral
    End date: 2012-07-26

Lyrica
    Administration route: Oral
    End date: 2012-07-26

Nexium
    Administration route: Oral

Nitroglycerin
    End date: 2012-07-27

Plavix
    Administration route: Oral

Ramipril
    Administration route: Oral
    End date: 2012-07-26

Zometa
    Start date: 2012-07-19
    End date: 2012-07-19

Possible Zometa side effects in female

Reported by a physician from France on 2012-08-24

Patient: female

Reactions: Agitation, Confusional State, Acute Pulmonary Oedema, Nephrolithiasis, Dyspnoea, Hypercalcaemia, Renal Failure Acute

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Acetaminophen
    Dosage: 1 mg, unk
    End date: 2012-07-26

Aspirin
    Dosage: 75 mg, unk

Atorvastatin
    Dosage: 10 mg, qd

Bisoprolol Fumarate
    Dosage: 3.75 mg, daily (2.5 mg in the morning and 1.25 mg in the evening)
    End date: 2012-07-27

Cymbalta
    Dosage: 60 mg, qd
    End date: 2012-07-26

Duragesic-100
    Dosage: 50 ug, daily
    End date: 2012-07-26

Lercanidipine
    Dosage: 10 mg, qd
    End date: 2012-07-26

Lyrica
    Dosage: 75 mg, bid
    End date: 2012-07-26

Nexium
    Dosage: 20 mg, qd
    End date: 2012-07-26

Nitroglycerin
    Dosage: 5 mg, daily
    End date: 2012-07-27

Plavix
    Dosage: 75 mg, qd
    End date: 2012-07-26

Ramipril
    Dosage: 10 mg, qd
    End date: 2012-07-26

Zometa
    Dosage: 4 mg, in 15 min
    Indication: Hypercalcaemia
    Start date: 2012-07-19

Possible Zometa side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-24

Patient: male, weighing 99.8 kg (219.5 pounds)

Reactions: Weight Decreased, Tooth Loss, Hand Fracture, Osteomyelitis, Tricuspid Valve Incompetence, Hypotonic Urinary Bladder, Chronic Obstructive Pulmonary Disease, Blepharitis, Cheilitis, Upper Respiratory Tract Infection, Oral Candidiasis, Oedema Peripheral, Hypoxia, Breath Odour, Urinary Retention, Arrhythmia Supraventricular, Cellulitis, Stomatitis, Angina Pectoris, Haematuria, Ataxia, Diverticulum, Gingival Erythema, Ventricular Tachycardia, Increased Tendency To Bruise, Mastication Disorder, Atelectasis, Exposed Bone in JAW, Aortic Valve Sclerosis, Bone Pain, Pain, Hepatic Lesion, Skin Reaction, Fall, Hypokalaemia, Ventricular Hypertrophy, Left Ventricular Dysfunction, Obesity, Oedema, Dizziness, Injury, Bone Disorder, Metastases To Lung, Neurogenic Bladder, Haemorrhoids, Hyponatraemia, Atrial Fibrillation, Cerebrovascular Accident, Anxiety, Dysgeusia, Prostatic Specific Antigen Increased, Osteonecrosis of JAW, Neoplasm Malignant, Impaired Healing, Mitral Valve Incompetence, Bronchitis, Bradycardia, Asthenia, Tooth Disorder, Metastases To Bone, Deep Vein Thrombosis

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa
    Dosage: 4 mg, every 4-6 weeks
    Indication: Prostate Cancer Metastatic
    Start date: 2002-01-01
    End date: 2005-07-27

Zometa
    Indication: Bone Neoplasm Malignant

Other drugs received by patient: Hydrochlorothiazide; Taxotere; Hormones and Related Agents; Cosmopen; Furosemide; Digoxin; Hormones; Taxol + Carboplatin; Tylenol; Aspirin; Erythromycin; Prednisone TAB; Darvocet-N 50; Influenza Virus Vaccine; Oxygen Therapy; Coumadin; Oxycodone HCL; Albuterol Sulfate; Zofran; Lovenox; Lupron; Atrovent; Casodex; Viadur

Possible Zometa side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-24

Patient: female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa

Possible Zometa side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-24

Patient: male

Reactions: Electrocardiogram ST-T Change, Angina Unstable, Osteomyelitis, Oral Cavity Fistula, Bundle Branch Block Right, Hyperhidrosis, Gynaecomastia, Oedema Peripheral, Bone Density Decreased, Arteriosclerosis, Lymphocyte Count Decreased, Back Pain, Hydronephrosis, Neutrophil Count Increased, Dysphagia, Subcutaneous Abscess, Anaemia, Coronary Artery Stenosis, Venous Insufficiency, Tremor, Hepatic Steatosis, Emotional Distress, Diverticulum, Alpha Haemolytic Streptococcal Infection, Swelling, Submandibular Mass, Abscess Soft Tissue, Pain, Neoplasm Progression, Constipation, Failure To Thrive, Bone Loss, Hyperparathyroidism, Pulmonary Congestion, Bronchospasm, Intervertebral Disc Degeneration, Urethral Pain, Exostosis, Renal Failure Acute, Blood Glucose Increased, Spinal Cord Compression, Oral Discharge, Nausea, Lung Neoplasm, Urinary Tract Infection, Deformity, Anxiety, Prostatic Specific Antigen Increased, Osteonecrosis of JAW, Neoplasm Malignant, Spinal Osteoarthritis, Sinus Tachycardia, Asthenia, Infection, Inflammation

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aredia
    Dosage: 90 mg, qmo
    Indication: Metastases To Bone
    Start date: 2005-01-01

Zometa

Other drugs received by patient: Casodex; Versed; Furosemide; Oxycontin; Penicillin V Potassium; Lisinopril; Zetia; Simvastatin; Lipitor; Aspirin; Metoprolol Tartrate; Ranexa; Verapamil; Integrilin; Plavix; Midazolam; Aspirin; Lovaza; Multi-Vitamin; Omeprazole; Symbicort; Nitroglycerin; Fentanyl; Celebrex; Oxycodone HCL and Acetaminophen; Lorazepam; Heparin; Proscar; Lopressor; Dilaudid; Isosorbide Mononitrate

Possible Zometa side effects in female

Reported by a physician from France on 2012-08-24

Patient: female

Reactions: Nephrolithiasis, Agitation, Confusional State, Acute Pulmonary Oedema, Dyspnoea, Hypercalcaemia, Renal Failure Acute

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Acetaminophen
    Dosage: 1 mg, unk
    End date: 2012-07-26

Aspirin
    Dosage: 75 mg, unk

Atorvastatin
    Dosage: 10 mg, qd

Bisoprolol Fumarate
    Dosage: 3.75 mg, daily (2.5 mg in the morning and 1.25 mg in the evening)
    End date: 2012-07-27

Cymbalta
    Dosage: 60 mg, qd
    End date: 2012-07-26

Duragesic-100
    Dosage: 50 ug, daily
    End date: 2012-07-26

Lercanidipine
    Dosage: 10 mg, qd
    End date: 2012-07-26

Lyrica
    Dosage: 75 mg, bid
    End date: 2012-07-26

Nexium
    Dosage: 20 mg, qd
    End date: 2012-07-26

Nitroglycerin
    Dosage: 5 mg, daily
    End date: 2012-07-27

Plavix
    Dosage: 75 mg, qd
    End date: 2012-07-26

Ramipril
    Dosage: 10 mg, qd
    End date: 2012-07-26

Zometa
    Dosage: 4 mg, in 15 min
    Indication: Hypercalcaemia
    Start date: 2012-07-19

Possible Zometa side effects in male

Reported by a lawyer from United States on 2012-08-24

Patient: male

Reactions: Electrocardiogram ST Segment Depression, Lymphadenopathy, Intra-Abdominal Haematoma, Angina Unstable, Diverticulitis, Tachycardia, Bundle Branch Block Right, Prothrombin Time Prolonged, Tricuspid Valve Incompetence, Hyperhidrosis, Chronic Obstructive Pulmonary Disease, Cardiomegaly, Oedema Peripheral, Pulpitis Dental, Arteriosclerosis, Back Pain, Mitral Valve Prolapse, Ventricular Extrasystoles, Abscess Oral, Cerumen Impaction, Prostate Cancer, Coronary Artery Disease, Left Ventricular Hypertrophy, Small Intestinal Obstruction, Vision Blurred, Lymphatic System Neoplasm, Neutropenia, Ischaemia, Fall, Rectosigmoid Cancer, Obesity, Aortic Arteriosclerosis, Chest Pain, Malignant Melanoma, Depression, Bone Disorder, Injury, Myocardial Infarction, Exostosis, Dyspnoea, Tooth Fracture, Excoriation, Gout, Lung Neoplasm, Haemorrhoids, Carotid Bruit, Haematochezia, Arthralgia, Mitral Valve Incompetence, Anisocytosis, Primary Sequestrum, Abdominal Hernia, Ischaemic Cardiomyopathy, Gingivitis, Gastrointestinal Haemorrhage, Enterococcal Infection, Sciatica, Osteomyelitis, Pulmonary Embolism, Pyrexia, Erectile Dysfunction, Colonic Polyp, Spinal Compression Fracture, Radiculopathy, Cardiac Failure Congestive, Pneumonia, Chest Discomfort, Pain in Extremity, Anaemia, Renal Cyst, Hypoaesthesia, Nasal Septum Deviation, Staphylococcal Sepsis, Bone Neoplasm Malignant, Spinal Column Stenosis, Atelectasis, Metastases To Abdominal Wall, Pain, Death, Frequent Bowel Movements, Electrocardiogram QRS Complex Prolonged, Splenic Granuloma, Pleural Effusion, Intervertebral Disc Degeneration, Sinusitis, Metastases To Lung, Splenic Calcification, Type 2 Diabetes Mellitus, Colon Cancer, Dental Caries, Atrial Fibrillation, Radicular Cyst, Hypercalcaemia, Osteoarthritis, Hyperlipidaemia, Neoplasm Malignant, Osteonecrosis of JAW, Respiratory Failure, Hypertension, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zometa

Other drugs received by patient: Aspirin; Lipitor; Aspirin; Aranesp; Ampicillin Sodium; Meperidine HCL; Nitroglycerin; Flagyl; Hydrochlorothiazide; Lupron; Augmentin '500'; Neulasta; Nystatin; Unasyn; Toprol-XL; Zofran; Zosyn; Magnesium; Dilaudid; Tylenol; Leucovorin Calcium; Oxycontin; Plavix; Ciprofloxacin; Lisinopril; Naltrexone Hydrochloride; Senokot; Fluorouracil; Avastin; Fluoxetine Hydrochloride; Flomax; Heparin; Lasix; Multi-Vitamin; Baclofen; Camptosar; Cefepime; Labetalol HCL; Ambien; Lopressor; Hydralazine HCL; Thalidomide; Protonix; Potassium Chloride (KV / 24); Roxicet

Possible Zometa side effects in female

Reported by a physician from United States on 2012-08-24

Patient: female

Reactions: Abdominal Pain, Lymphadenopathy, Brain Mass, Metastases To Liver, Headache, Seroma, Hot Flush, Osteoradionecrosis, Uterine Leiomyoma, Hydrocephalus, Brain Neoplasm, Haematoma, Back Pain, Cushingoid, Breast Cancer, Breast Mass, Ataxia, Perirectal Abscess, Intestinal Obstruction, Metastases To Abdominal Cavity, Small Intestinal Obstruction, Osteosclerosis, Bone Neoplasm Malignant, Hepatic Cyst, Metastases To Spine, Compression Fracture, Aortic Valve Incompetence, Metastases To Central Nervous System, Atelectasis, Aphasia, Necrosis, Pneumocephalus, Constipation, Muscle Strain, Neuropathy Peripheral, Neck Pain, Oedema, Intervertebral Disc Degeneration, Pleural Effusion, Dizziness, Thrombocytopenia, Scoliosis, Emphysema, Colon Cancer, Dyspnoea, Vomiting, Swelling Face, Nausea, Hyperlipidaemia, Osteonecrosis of JAW, Neoplasm Malignant, Mitral Valve Incompetence, DRY Eye, Metastases To Bone, Hypertension, Atrophy

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zometa

Other drugs received by patient: Avastin; Herceptin; Oxycontin; Taxotere; Motrin; Lortab

Possible Zometa side effects in male

Reported by a consumer/non-health professional from Australia on 2012-08-24

Patient: male

Reactions: Respiratory Failure, Osteonecrosis of JAW, Pain, Swelling, Gingival Infection, Lower Respiratory Tract Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa

Possible Zometa side effects in female

Reported by a physician from France on 2012-08-24

Patient: female

Reactions: Confusional State, Nephrolithiasis, Acute Pulmonary Oedema, Agitation, Dyspnoea, Hypercalcaemia, Renal Failure Acute

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Acetaminophen
    Dosage: 1 mg, unk
    End date: 2012-07-26

Aspirin
    Dosage: 75 mg, unk

Atorvastatin
    Dosage: 10 mg, qd

Bisoprolol Fumarate
    Dosage: 3.75 mg, daily (2.5 mg in the morning and 1.25 mg in the evening)
    End date: 2012-07-27

Cymbalta
    Dosage: 60 mg, qd
    End date: 2012-07-26

Duragesic-100
    Dosage: 50 ug, daily
    End date: 2012-07-26

Lercanidipine
    Dosage: 10 mg, qd
    End date: 2012-07-26

Lyrica
    Dosage: 75 mg, bid
    End date: 2012-07-26

Nexium
    Dosage: 20 mg, qd
    End date: 2012-07-26

Nitroglycerin
    Dosage: 5 mg, daily
    End date: 2012-07-27

Plavix
    Dosage: 75 mg, qd
    End date: 2012-07-26

Ramipril
    Dosage: 10 mg, qd
    End date: 2012-07-26

Zometa
    Dosage: 4 mg, in 15 min
    Indication: Hypercalcaemia
    Start date: 2012-07-19

Possible Zometa side effects in male

Reported by a consumer/non-health professional from Netherlands on 2012-08-23

Patient: male

Reactions: Abdominal Discomfort, Septic Shock, Clostridial Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa
    Dosage: 4 mg/100 ml every 5 weeks
    Start date: 2012-01-05
    End date: 2012-01-01

Zometa
    Dosage: 4 mg/100 ml every 5 weeks
    Indication: Metastases To Bone
    Start date: 2011-02-01

Zometa
    Dosage: 4 mg/100 ml every 5 weeks
    Start date: 2011-03-01

Zometa
    Dosage: 4 mg/100 ml every 5 weeks
    Start date: 2011-11-30

Other drugs received by patient: Prednisone TAB; Docetaxel

Possible Zometa side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-23

Patient: female

Reactions: Tooth Loss, Tachycardia, Diverticulitis, Coma, Paralysis, Oral Cavity Fistula, Chronic Obstructive Pulmonary Disease, Oesophagitis, Gallbladder Disorder, Hypotension, Pseudomonas Infection, Coronary Artery Disease, Small Intestinal Obstruction, Emotional Distress, Diverticulum, Swelling, Exposed Bone in JAW, Metastases To Lymph Nodes, Gastric Ulcer, Abdominal Pain Upper, Ventricular Hypertrophy, Aortic Arteriosclerosis, Bone Disorder, Vomiting, Cataract, Lung Neoplasm, Arrhythmia, Syncope, Physical Disability, Gastrointestinal Haemorrhage, Osteomyelitis, Proteinuria, Tenderness, Radiculopathy, Laryngotracheal Oedema, Dysphagia, Hiatus Hernia, Cellulitis, Subclavian Artery Stenosis, Anaemia, Adenomyosis, Cholelithiasis, Iliac Artery Stenosis, Fistula Discharge, Adenoma Benign, Purulent Discharge, Atelectasis, Tooth Abscess, Central Nervous System Lesion, Pain, Hypokalaemia, Gastritis, Partial Seizures, Dyspnoea Exertional, Fatigue, Dizziness, Intervertebral Disc Degeneration, Pain in JAW, Pharyngitis, Swelling Face, Peripheral Vascular Disorder, Urinary Tract Infection, Atrial Fibrillation, Cholecystitis Chronic, Cerebrovascular Accident, Hypercalcaemia, Deformity, Hyperlipidaemia, Anxiety, Renal Failure, Osteonecrosis of JAW, Diarrhoea, Vertigo, Peripheral Arterial Occlusive Disease, Hypertension, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aredia

Fosamax

Pamidronate Disodium

Zometa

Other drugs received by patient: Vicodin; Ambien; Hydrochlorothiazide; Pentoxifylline; Magnesium; Lisinopril; Lipitor; Pletal; Femara; Procrit; Niacin; Vitamin TAB; Quinine Sulfate; Levaquin; Plavix; Tobramycin; Letrozole; Simvastatin; Clonidine; Ciprofloxacin HCL; Aspirin; Dyazide; Potassium; Norvasc

Possible Zometa side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-23

Patient: female

Reactions: Tooth Loss, Upper Respiratory Tract Infection, Oedema Peripheral, Back Pain, Phlebitis, Vaginal Discharge, Osteitis, Irritability, Diabetic Neuropathy, Swelling, Metastases To Spine, Vision Blurred, Metastases To Central Nervous System, Exposed Bone in JAW, Polyuria, Mental Status Changes, Metastases To Lymph Nodes, Fall, Chest Pain, Obesity, Depression, Injury, Vomiting, Dyspnoea, Gout, Arrhythmia, Oral Pain, Alopecia, Loose Tooth, Metastases To Bone, Urinary Incontinence, Osteomyelitis, Pulmonary Embolism, Headache, Cerebral Ischaemia, Oral Candidiasis, HIV Infection, Breath Odour, Cellulitis, Pain in Extremity, General Physical Health Deterioration, Hypoaesthesia, Vocal Cord Paralysis, Abscess JAW, Paraesthesia, Convulsion, Vasogenic Cerebral Oedema, Acute Sinusitis, Fungal Infection, Dehydration, Insomnia, Haemorrhagic Diathesis, Depressed Level of Consciousness, Confusional State, Dyslipidaemia, Neoplasm Progression, Failure To Thrive, Constipation, Hypokalaemia, Myalgia, Neuropathy Peripheral, Dizziness, Gastrooesophageal Reflux Disease, Pain in JAW, Metastases To Lung, Oral Discharge, Nausea, Acquired Immunodeficiency Syndrome, Hyponatraemia, Cerebral Atrophy, Facial Pain, Osteoarthritis, Anxiety, Osteonecrosis of JAW, Vertigo, Hypertension, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aredia
    Dosage: 90 mg, qmo
    Indication: Neoplasm Malignant

Zometa
    Dosage: 4 mg, qmo
    Indication: Metastases To Bone

Zometa
    Indication: Osteoporosis

Other drugs received by patient: Lasix; Glucovance; Prozac; Toradol; Lorazepam; Decadron Phosphate; Norco; Dexamethasone; Protonix; Zofran; Coumadin; Neurontin; Fosamax; Ritalin; Humalog; Hydrocodone; Reglan; Crestor

Possible Zometa side effects in female

Reported by a physician from United States on 2012-08-23

Patient: female

Reactions: Abdominal Pain, Brain Mass, Lymphadenopathy, Metastases To Liver, Headache, Seroma, Hot Flush, Osteoradionecrosis, Uterine Leiomyoma, Hydrocephalus, Brain Neoplasm, Haematoma, Back Pain, Breast Cancer, Cushingoid, Ataxia, Breast Mass, Perirectal Abscess, Intestinal Obstruction, Metastases To Abdominal Cavity, Small Intestinal Obstruction, Osteosclerosis, Bone Neoplasm Malignant, Hepatic Cyst, Compression Fracture, Metastases To Spine, Metastases To Central Nervous System, Aortic Valve Incompetence, Atelectasis, Aphasia, Necrosis, Pneumocephalus, Constipation, Muscle Strain, Neuropathy Peripheral, Neck Pain, Dizziness, Pleural Effusion, Intervertebral Disc Degeneration, Oedema, Thrombocytopenia, Emphysema, Scoliosis, Vomiting, Swelling Face, Nausea, Hyperlipidaemia, Osteonecrosis of JAW, Neoplasm Malignant, Mitral Valve Incompetence, Metastases To Bone, Hypertension, DRY Eye, Atrophy

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zometa

Other drugs received by patient: Oxycontin; Motrin; Taxotere; Herceptin; Avastin; Lortab

Possible Zometa side effects in male

Reported by a physician from Japan on 2012-08-23

Patient: male, weighing 50.0 kg (110.0 pounds)

Reactions: Renal Impairment, C-Reactive Protein Increased, Neoplasm Malignant, Neoplasm Progression, Pyrexia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Afinitor
    Dosage: 5 mg, daily
    Administration route: Oral
    Start date: 2012-01-06
    End date: 2012-01-09

Afinitor
    Dosage: 5 mg, daily
    Administration route: Oral
    Start date: 2011-12-14
    End date: 2011-12-29

Afinitor
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Metastatic Renal Cell Carcinoma
    Start date: 2011-06-20
    End date: 2011-10-03

Etodolac
    Dosage: 400 mg, daily
    Administration route: Oral
    Indication: Metastatic Renal Cell Carcinoma

Prednisolone
    Dosage: 5 mg
    Administration route: Oral
    Indication: Metastatic Renal Cell Carcinoma
    Start date: 2011-06-21
    End date: 2011-09-01

Zometa
    Dosage: unk ukn, unk
    Indication: Metastatic Renal Cell Carcinoma
    Start date: 2011-06-27

Other drugs received by patient: Allopurinol; Benidipine Hydrochloride; Vitamin B12; Limaprost Alfadex; Lansoprazole; Limaprost Alfadex; Flivas; Acetaminophen

Possible Zometa side effects in

Reported by a physician from United States on 2012-08-23

Patient:

Reactions: Polyp Colorectal, Gastrointestinal Haemorrhage, Breast Cancer in Situ, Oedema Peripheral, Congenital Anomaly, Adverse Event, Oedema Mouth, Post Procedural Infection, Anaemia Postoperative, Cellulitis, Pneumonia, Functional Gastrointestinal Disorder, Drug Intolerance, Anaemia, Venous Insufficiency, Intestinal Obstruction, Small Intestinal Obstruction, Metastases To Spine, Dental Necrosis, Compression Fracture, Venous Thrombosis, Abscess, Peutz-Jeghers Syndrome, Tooth Abscess, Haemorrhage, Multiple Myeloma, Periodontitis, Skin Ulcer, Periodontal Infection, Bronchioloalveolar Carcinoma, Thrombocytopenia, Transient Ischaemic Attack, RIB Fracture, Intestinal Polyp, Swelling Face, Urinary Tract Infection, Arrhythmia, Osteoarthritis, Mallory-Weiss Syndrome, Respiratory Failure, Oral Pain, Osteonecrosis of JAW, Biopsy Lymph Gland Abnormal, Hypothyroidism, Tooth Disorder, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aredia
    Indication: Multiple Myeloma

Fosamax
    Administration route: Oral
    Start date: 1996-01-01

Zometa
    Indication: Multiple Myeloma
    Start date: 2006-05-30

Other drugs received by patient: Interferon Alfa

Possible Zometa side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-23

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa

Possible Zometa side effects in male

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-08-23

Patient: male

Reactions: Confusional State, Death, Dehydration, General Physical Health Deterioration, Hypertension, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Zometa
    Dosage: 4 mg/100 ml, 1 x every 28 days
    Start date: 2012-06-11

Zometa
    Dosage: 4 mg/100 ml, 1 x every 28 days
    Start date: 2012-07-01

Zometa
    Dosage: 4 mg/100 ml, 1 x every 28 days
    Indication: Prostate Cancer Metastatic
    Start date: 2012-01-24

Zometa
    Dosage: 4 mg/100 ml, 1 x every 28 days
    Start date: 2012-08-08
    End date: 2012-08-08

Possible Zometa side effects in male

Reported by a consumer/non-health professional from Korea, Republic of on 2012-08-22

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Zometa