Index of reports
> Cases with Pleural Effusion (8)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Zolinza (Vorinostat) where reactions include pleural effusion. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Zolinza side effects in
Reported by a consumer/non-health professional from Japan on 2012-08-23
Patient:
Reactions: Vomiting, Nausea, Alanine Aminotransferase Increased, Eosinophilic Pneumonia Acute, Parotitis, Constipation, Death, Aspartate Aminotransferase Increased, Platelet Count Decreased, Pleural Effusion, Deep Vein Thrombosis, Decreased Appetite
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Zolinza
Dosage: 400 mg, qd
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2011-11-10
End date: 2011-11-21
Zolinza
Dosage: 300 mg, qd
Administration route: Oral
Start date: 2012-01-02
End date: 2012-01-14
Zolinza
Dosage: 300 mg, qd
Administration route: Oral
Start date: 2011-11-29
End date: 2011-12-01
Zolinza
Dosage: 300 mg, qd
Administration route: Oral
Start date: 2011-12-08
End date: 2011-12-26
Other drugs received by patient: Pantethine; Allegra; Armodafinil; Maglax (Magnesium Oxide); Lantus; Rabeprazole Sodium; Novorapid; Lipitor
Possible Zolinza side effects in female
Reported by a physician from United States on 2012-06-04
Patient: female, weighing 64.9 kg (142.8 pounds)
Reactions: White Blood Cell Count Decreased, Pneumonia, Febrile Neutropenia, Disease Progression, Cardiac Failure, Injection Site Reaction, Sepsis, Pleural Effusion, Neutrophil Count Decreased
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Zolinza
Dosage: 400 milligram
Administration route: Oral
Start date: 2011-11-04
End date: 2011-11-12
Vidaza
Dosage: 125 milligram/sq. meter
Start date: 2011-11-04
End date: 2011-11-10
Vidaza
Dosage: 75 milligram/sq. meter
Start date: 2011-10-04
End date: 2011-10-10
Zolinza
Dosage: 400 milligram
Administration route: Oral
Start date: 2011-10-04
End date: 2011-10-12
Mylotarg
Dosage: 3 milligram/sq. meter
Start date: 2011-10-04
End date: 2011-10-11
Mylotarg
Dosage: 5.1 milligram
Start date: 2011-11-07
End date: 2011-11-11
Other drugs received by patient: Levothyroxine Sodium; Diphenhydramine HCL; Lipitor; Hydrocodone
Possible Zolinza side effects in 66 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-16
Patient: 66 year old female, weighing 64.9 kg (142.8 pounds)
Reactions: White Blood Cell Count Decreased, Pneumonia, Cardiac Failure, Injection Site Reaction, Pleural Effusion, Febrile Neutropenia, Neutrophil Count Decreased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Mylotarg
Dosage: 3 milligram/sq. meter
Start date: 2011-10-04
End date: 2011-10-11
Zolinza
Dosage: 400 milligram
Administration route: Oral
Start date: 2011-11-04
End date: 2011-11-12
Vidaza
Dosage: 75 milligram/sq. meter
Start date: 2011-10-04
End date: 2011-10-10
Mylotarg
End date: 2011-11-11
Zolinza
Dosage: 400 milligram
Administration route: Oral
Start date: 2011-10-04
End date: 2011-10-12
Vidaza
Dosage: 75 milligram/sq. meter
Start date: 2011-11-04
Other drugs received by patient: Hydrocodone; Lipitor; Diphenhydramine HCL; Levothyroxine Sodium
Possible Zolinza side effects in 63 year old female
Reported by a physician from Japan on 2012-03-19
Patient: 63 year old female
Reactions: Vomiting, Nausea, Alanine Aminotransferase Increased, General Physical Health Deterioration, Eosinophilic Pneumonia Acute, Parotitis, Constipation, Aspartate Aminotransferase Increased, Pleural Effusion, Decreased Appetite, Deep Vein Thrombosis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Zolinza
Dosage: 400 mg/daily 300 mg/daily
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2011-11-10
End date: 2011-11-21
Zolinza
Dosage: 400 mg/daily 300 mg/daily
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2011-11-29
End date: 2011-12-01
Zolinza
Dosage: 400 mg/daily 300 mg/daily
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2012-01-02
End date: 2012-01-14
Zolinza
Dosage: 400 mg/daily 300 mg/daily
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2011-12-08
End date: 2011-12-26
Other drugs received by patient: Pantethine; Lipitor; Lantus; Allegra; Diflucan; Novorapid; Rabeprazole Sodium; Maglax (Magnesium Oxide)
Possible Zolinza side effects in 66 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-28
Patient: 66 year old female, weighing 64.9 kg (142.8 pounds)
Reactions: White Blood Cell Count Decreased, Cardiac Failure, Injection Site Reaction, Febrile Neutropenia, Pleural Effusion, Pneumonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Mylotarg
Dosage: 3 milligram/sq. meter
Start date: 2011-10-04
End date: 2011-10-11
Vidaza
Dosage: 75 milligram/sq. meter
Start date: 2011-10-04
End date: 2011-10-10
Zolinza
Dosage: 400 milligram
Administration route: Oral
Start date: 2011-10-04
End date: 2011-10-12
Other drugs received by patient: Levothyroxine Sodium; Lipitor; Diphenhydramine HCL; Hydrocodone
Possible Zolinza side effects in 63 year old female
Reported by a individual with unspecified qualification from Japan on 2012-02-23
Patient: 63 year old female
Reactions: Interstitial Lung Disease, Pleural Effusion
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Zolinza
Possible Zolinza side effects in 66 year old female
Reported by a physician from United States on 2012-01-26
Patient: 66 year old female, weighing 64.9 kg (142.8 pounds)
Reactions: White Blood Cell Count Decreased, Cardiac Failure, Injection Site Reaction, Febrile Neutropenia, Pleural Effusion, Pneumonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zolinza
Dosage: 400 mg, on days 1-9
Administration route: Oral
Indication: Acute Myeloid Leukaemia
Start date: 2011-10-04
End date: 2011-10-12
Mylotarg
Dosage: 3 mg/m2, on days 4 and 8
Indication: Acute Myeloid Leukaemia
Start date: 2011-10-04
End date: 2011-10-11
Vidaza
Dosage: 75 mg/m2, on days 1-7
Indication: Acute Myeloid Leukaemia
Start date: 2011-10-04
End date: 2011-10-10
Other drugs received by patient: Hydrocodone; Lipitor; Benadryl; Levothyroxine Sodium
Possible Zolinza side effects in 66 year old female
Reported by a physician from United States on 2011-11-23
Patient: 66 year old female, weighing 64.9 kg (142.8 pounds)
Reactions: White Blood Cell Count Decreased, Cardiac Failure, Injection Site Reaction, Febrile Neutropenia, Pleural Effusion, Pneumonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Azacitidine
Dosage: 75 mg/m2/day, sc or iv on days 1-7 (total dose this course: 896mg)
Indication: Acute Myeloid Leukaemia
Start date: 2011-10-04
End date: 2011-10-10
Zolinza
Dosage: 400 mg, 1x/day on days 1-9 (total dose this course: 3600mg)
Administration route: Oral
Indication: Acute Myeloid Leukaemia
Start date: 2011-10-04
End date: 2011-10-12
Mylotarg
Dosage: 3 mg/m2, over 2 hrs on days 4 and 8 (total dose this course: 10.2mg)
Indication: Acute Myeloid Leukaemia
Start date: 2011-10-04
End date: 2011-10-11
Other drugs received by patient: Levothyroxine Sodium; Benadryl; Hydrocodone; Lipitor
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