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Zocor (Simvastatin) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (63)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Zocor (Simvastatin) where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 63   Next >>

Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-14

Patient:

Reactions: Drug Interaction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Emtricitabine
    Indication: HIV Infection

Fosamprenavir Calcium
    Indication: HIV Infection

Ritonavir
    Indication: HIV Infection

Tenofovir Disoproxil Fumarate
    Indication: HIV Infection

Other drugs received by patient: Pravastatin Sodium; Aspirin; Clopidogrel; Gliclazide



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-14

Patient:

Reactions: Myositis, Blood Creatine Phosphokinase Increased, Cellulitis, Alanine Aminotransferase Increased, Drug Interaction, Myopathy, Oedema Peripheral, Liver Function Test Abnormal, Asthenia, Mobility Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Itraconazole
    Dosage: 100 mg, bid
    Administration route: Oral
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-03-06
    End date: 2012-04-12

Other drugs received by patient: Corticosteroids (Unspecified)



Possible Zocor side effects in

Reported by a pharmacist from Australia on 2012-08-10

Patient:

Reactions: Rhabdomyolysis, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Voriconazole
    Dosage: 200 mg, bid
    Administration route: Oral

Other drugs received by patient: Insulin



Possible Zocor side effects in

Reported by a consumer/non-health professional from United Kingdom on 2012-08-10

Patient:

Reactions: Myositis, Blood Creatine Phosphokinase Increased, Cellulitis, Alanine Aminotransferase Increased, Drug Interaction, Myopathy, Liver Function Test Abnormal, Oedema Peripheral, Asthenia, Mobility Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Itraconazole
    Dosage: 100 mg, bid
    Administration route: Oral
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-03-06
    End date: 2012-04-12

Other drugs received by patient: Corticosteroids (Unspecified)



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-06

Patient:

Reactions: Rhabdomyolysis, Drug Interaction

Drug(s) suspected as cause:
Norfloxacin

Zocor
    Dosage: unk



Possible Zocor side effects in

Reported by a consumer/non-health professional from United States on 2012-08-05

Patient:

Reactions: Myalgia, Arthropathy, Pain in Extremity, Drug Interaction, Muscle Tightness

Drug(s) suspected as cause:
Amlodipine Besylate
    Dosage: 10 mg, qd

Zocor
    Dosage: 20 mg, qd
    Administration route: Oral



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-05

Patient:

Reactions: Drug Effect Decreased, Drug Interaction

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Bystolic

Clopidogrel Bisulfate

Valsartan

Viagra



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-03

Patient:

Reactions: International Normalised Ratio Increased, Anaemia, International Normalised Ratio Decreased, Drug Interaction, Transaminases Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Acetaminophen
    Dosage: up to four times a day, as needed
    Administration route: Oral

Cymbalta
    Dosage: 69 mg, qd
    Administration route: Oral

Warfarin Sodium
    Dosage: 1 to 6 mg, qd
    Administration route: Oral

Zocor
    Dosage: 20 mg, qd
    Administration route: Oral

Other drugs received by patient: Lidocaine; Lantus; Metoprolol Tartrate; Insulin Lispro; Vitamins (Unspecified); Amlodipine Besylate; Gabapentin; Oxycodone HCL



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-03

Patient:

Reactions: Malaise, Fatigue, Blood Urine Present, Rhabdomyolysis, Hepatotoxicity, Drug Interaction, Muscular Weakness, Blood Creatinine Increased

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Cyproterone Acetate
    Dosage: 300 mg, tid
    Administration route: Oral

Zocor
    Dosage: 40 mg, qd
    Administration route: Oral

Other drugs received by patient: Prostep; Allopurinol; Aspirin; Bendroflumethiazide; Atenolol



Possible Zocor side effects in

Reported by a consumer/non-health professional from United States on 2012-08-03

Patient:

Reactions: Balance Disorder, Muscular Weakness, Drug Interaction, Blood Magnesium Decreased, Feeling Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Azor
    Dosage: 5 mg, qd
    Administration route: Oral

Azor
    Dosage: 10-40
    Administration route: Oral

Other drugs received by patient: Aspirin; Metformin Hydrochloride



Possible Zocor side effects in

Reported by a consumer/non-health professional from United States on 2012-08-02

Patient:

Reactions: Abdominal Pain, Rhabdomyolysis, Pain, Drug Interaction, Tricuspid Valve Incompetence, Myopathy Toxic, Ileus, Iron Deficiency Anaemia, Abdominal Distension, Blood Creatinine Increased, Erosive Duodenitis, Alanine Aminotransferase Increased, Muscular Weakness, Renal Failure Chronic, Paraesthesia, Irritability, Haemoglobin Decreased, Aspartate Aminotransferase Increased, Mitral Valve Incompetence, Myotonia, Gait Disturbance

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Amlodipine
    Dosage: 8 mg, unk

Doxazosin Mesylate
    Dosage: 5 mg, unk

Gemfibrozil
    Dosage: 60 mg, bid

Proscar
    Dosage: 5 mg, unk
    Administration route: Oral

Zocor
    Dosage: 40 mg, qd

Other drugs received by patient: Lisinopril; Levothyroxine Sodium; Lactulose; Ergocalciferol; Furosemide; Ferrous Sulfate TAB; Hydralazine HCL; Lantus; Aspirin; Metoprolol Tartrate; Travoprost; Sodium Polystyrene Sulfonate



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-02

Patient:

Reactions: Abdominal Pain, Rhabdomyolysis, Drug Interaction, Abdominal Distension, Renal Failure Chronic, Myopathy

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amlodipine Besylate
    Dosage: 10 mg, qd

Doxazosin Mesylate
    Dosage: 8 mg, qd

Finasteride
    Dosage: 5 mg, qd

Gemfibrozil
    Dosage: 600 mg, bid

Zocor
    Dosage: 20 mg, qd
    Administration route: Oral

Zocor
    Dosage: 40 mg, qd
    Administration route: Oral

Other drugs received by patient: Lantus; Lisinopril; Aspirin; Furosemide; Hydralazine HCL; Lactulose; Levothyroxine Sodium; Travoprost; Ergocalciferol; Ferrous Sulfate TAB; Sodium Polystyrene Sulfonate; Metoprolol Tartrate



Possible Zocor side effects in

Reported by a physician from United Kingdom on 2012-08-01

Patient:

Reactions: Myositis, Blood Creatine Phosphokinase Increased, Alanine Aminotransferase Increased, Drug Interaction, Myopathy, Oedema Peripheral, Liver Function Test Abnormal, Asthenia, Mobility Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Itraconazole
    Dosage: 100 mg, bid
    Administration route: Oral
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-03-06
    End date: 2012-04-14

Other drugs received by patient: Corticosteroids (Unspecified)



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-01

Patient:

Reactions: International Normalised Ratio Increased, Drug Interaction, Transaminases Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Acetaminophen
    Dosage: up to 4 times daily when required
    Administration route: Oral

Cymbalta

Warfarin Sodium
    Dosage: 1-6 mg, qd

Other drugs received by patient: Lidocaine; Oxycodone HCL; Gabapentin; Lantus; Vitamins (Unspecified); Insulin Lispro; Metoprolol Tartrate; Amlodipine



Possible Zocor side effects in

Reported by a consumer/non-health professional from United States on 2012-08-01

Patient:

Reactions: Rhabdomyolysis, Dyspnoea, Prostate Cancer, Muscular Weakness, Drug Interaction, Paraesthesia, Fatigue, Mobility Decreased

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Cyproterone Acetate
    Dosage: 100 mg, tid
    Administration route: Oral

Zocor
    Dosage: 40 mg, unk
    Administration route: Oral

Other drugs received by patient: Atenolol; Bendroflumethiazide; Allopurinol; Prostep; Aspirin



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-01

Patient:

Reactions: Rhabdomyolysis, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Ciproflaxacin
    Dosage: unk

Other drugs received by patient: Ramipril; Carvedilol



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-01

Patient:

Reactions: Haemoglobin Decreased, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, International Normalised Ratio Increased, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Acetaminophen
    Dosage: 650 mg, qid
    Administration route: Oral

Cymbalta
    Dosage: 50 mg, qd

Warfarin
    Dosage: 1-6 mg, qd
    Administration route: Oral

Zocor
    Dosage: 20 mg, qd
    Administration route: Oral



Possible Zocor side effects in

Reported by a consumer/non-health professional from United States on 2012-08-01

Patient:

Reactions: Rhabdomyolysis, Abasia, Drug Interaction, Fall

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clarithromycin

Zocor
    Administration route: Oral

Other drugs received by patient: Amoxicillin; Omeprazole



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient:

Reactions: Muscle Necrosis, Rhabdomyolysis, Muscle Atrophy, Drug Interaction, Myopathy

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Noroxin
    Administration route: Oral



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient:

Reactions: Night Sweats, Myositis, Liver Injury, Rhabdomyolysis, Listless, Metabolic Acidosis, Muscular Weakness, Drug Interaction, General Physical Health Deterioration, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Amlodipine Besylate
    Dosage: 10 mg, qd
    Administration route: Oral

Other drugs received by patient: Lisinopril; Aspirin; Lanoxin



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient:

Reactions: Haemoglobin Decreased, Hepatic Function Abnormal, Haematocrit Decreased, International Normalised Ratio Increased, Aspartate Aminotransferase Increased, International Normalised Ratio Decreased, Alanine Aminotransferase Increased, Drug Interaction, Hepatitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Acetaminophen
    Dosage: 650 mg, prn
    Administration route: Oral

Cymbalta
    Dosage: 60 mg, qd

Warfarin Sodium
    Dosage: 1 df, unk

Other drugs received by patient: Lidocaine; Gabapentin; Lantus; Insulin Lispro; Vitamins (Unspecified); Oxycodone HCL; Amlodipine; Metoprolol Tartrate



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-31

Patient:

Reactions: Nausea, Hyperglycaemia, Drug Interaction, Headache, Diarrhoea, Vision Blurred, Eye Swelling, Dizziness, DRY Eye, Eye Pruritus

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Omega-3 Marine Triglycerides

Other drugs received by patient: Fexofenadine Hydrochloride; Glucophage; Diamicron MR



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient:

Reactions: Localised Infection, Rhabdomyolysis, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fusidic Acid
    Dosage: 250 mg, bid
    Administration route: Oral

Zocor
    Dosage: 40 mg, qd
    Administration route: Oral

Other drugs received by patient: Nicorandil; Floxacillin Sodium; Cilostazol; Omeprazole



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient:

Reactions: Myositis, Hepatic Enzyme Abnormal, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Alanine Aminotransferase Increased, Muscular Weakness, Drug Interaction, Muscle Enzyme Increased, Myoglobin Blood Increased, Cardiotoxicity, Gait Disturbance

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Imatinib Mesylate
    Dosage: 200 mg, qd
    Administration route: Oral

Other drugs received by patient: Aspirin; Zolpidem Tatrate; Ramipril; Centyl; Nexium



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-30

Patient:

Reactions: Abdominal Pain, Pain in Extremity, Pain, Necrosis, Muscular Weakness, Drug Interaction, Tricuspid Valve Incompetence, Renal Failure Chronic, Haemodialysis, Myopathy, Paraesthesia, Ileus, Iron Deficiency Anaemia, Mitral Valve Incompetence, Abdominal Distension, Gait Disturbance, Erosive Duodenitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amlodipine Besylate
    Dosage: 10 mg, qd
    Administration route: Oral

Doxazosin Mesylate
    Dosage: 8 mg, qd
    Administration route: Oral

Gemfibrozil
    Dosage: 600 mg, unk
    Administration route: Oral

Proscar
    Dosage: 5 mg, qd
    Administration route: Oral

Zocor
    Dosage: 20 mg, qd
    Administration route: Oral

Other drugs received by patient: Ferrous Sulfate TAB; Sodium Polystyrene Sulfonate; Hydralazine HCL; Metoprolol Tartrate; Aspirin; Lantus; Lactulose; Travoprost; Levothyroxine Sodium; Lisinopril; Ergocalciferol; Furosemide



Possible Zocor side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-30

Patient:

Reactions: Weight Decreased, Liver Injury, Myositis, Night Sweats, Blood Urine Present, Rhabdomyolysis, Metabolic Acidosis, Listless, Drug Interaction, General Physical Health Deterioration, Albumin Urine Present, Oliguria, Gait Disturbance, Renal Failure Acute, Decreased Appetite

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Amlodipine Besylate
    Dosage: 10 mg, qd
    Administration route: Oral

Zocor
    Dosage: 80 mg, qd
    Administration route: Oral

Other drugs received by patient: Metoprolol Tartrate; Lisinopril; Lanoxin; Aspirin



Possible Zocor side effects in

Reported by a physician from United Kingdom on 2012-07-27

Patient:

Reactions: Myositis, Blood Creatine Phosphokinase Increased, Cellulitis, Alanine Aminotransferase Increased, Drug Interaction, Myopathy, Oedema Peripheral, Liver Function Test Abnormal, Asthenia, Mobility Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Itraconazole
    Dosage: 100 mg, bid
    Administration route: Oral
    Indication: Bronchopulmonary Aspergillosis
    Start date: 2012-03-06
    End date: 2012-04-14

Other drugs received by patient: Corticosteroids (Unspecified)



Possible Zocor side effects in

Reported by a lawyer from United States on 2012-07-11

Patient:

Reactions: Back Pain, Renal Impairment, Rhabdomyolysis, Coronary Artery Occlusion, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Zocor

Other drugs received by patient possibly interacting with the suspect drug:
Cyclosporine
    Dosage: unk
    Indication: Transplant Rejection
    Start date: 1991-05-01

Zocor
    Dosage: 80 unk, unk
    Administration route: Oral
    Start date: 2010-06-01



Possible Zocor side effects in 57 year old male

Reported by a consumer/non-health professional from United States on 2012-07-10

Patient: 57 year old male

Reactions: Rhabdomyolysis, Renal Impairment, Coronary Artery Occlusion, General Physical Health Deterioration, Drug Interaction, Toxicity To Various Agents

Drug(s) suspected as cause:
Simvastatin
    Indication: Blood Cholesterol

Zocor
    Dosage: 40 mg, 1 in 1 d, unknown
    Indication: Blood Cholesterol
    End date: 2010-01-01



Possible Zocor side effects in 86 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-02

Patient: 86 year old male

Reactions: Rhabdomyolysis, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Oxeol
    Administration route: Oral
    Indication: Chronic Obstructive Pulmonary Disease
    Start date: 2012-01-01

Zocor
    Administration route: Oral
    Start date: 2011-02-01
    End date: 2012-03-02

Other drugs received by patient: Furosemide; Ramipril; Lantus; Kardegic; Alfuzosin HCL; Mirtazapine



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