This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Zemplar (Paricalcitol) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (353)
Death (102)
Life Threatening Events (14)
Disability (5)
Reports by Reaction Type
Dyspnoea (26),
Death (17),
Cardiac Failure (16),
Diarrhoea (16),
Renal Failure Chronic (15),
Fatigue (14),
Dizziness (14),
Myocardial Infarction (14),
Nausea (13),
Cardiac Arrest (13),
General Physical Health Deterioration (12),
Renal Failure (12)
Below are a few examples of reports where side effects / adverse reactions may be related to Zemplar (Paricalcitol). For a complete list or a specific selection of reports, please use the links above.
Possible Zemplar side effects in female
Reported by a physician from Germany on 2012-08-23
Patient: female, weighing 64.0 kg (140.8 pounds)
Reactions: Metabolic Acidosis, Hyperkalaemia, Iron Deficiency Anaemia, Bile Duct Stone, Tooth Extraction, Phosphorus Metabolism Disorder
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Indication: Renal Failure Chronic
Start date: 2010-12-10
Zemplar
Indication: Hyperparathyroidism Secondary
Other drugs received by patient: Carbabeta; Renagel; Iron(ii)succinate (Ferrlecit); Colecalciferole (Dekristol); Aranesp; Aranesp; Acetylsalicylic Acid SRT; Methimazole; Citalopram Hydrobromide; Amlodipine; Omeprazole; Nephrotrans; Methimazole; Losartan (Lorzaar); Aranesp; Benazepril Hydrochloride
Possible Zemplar side effects in 75 year old female
Reported by a physician from Germany on 2012-08-23
Patient: 75 year old female, weighing 77.0 kg (169.4 pounds)
Reactions: Spinal Fracture, Gastroenteritis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Aranesp
Possible Zemplar side effects in 61 year old male
Reported by a physician from Germany on 2012-08-22
Patient: 61 year old male, weighing 123.0 kg (270.6 pounds)
Reactions: Hospitalisation, Diabetic Retinopathy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Possible Zemplar side effects in female
Reported by a physician from Romania on 2012-08-21
Patient: female, weighing 55.0 kg (121.0 pounds)
Reactions: Renal Hypertension, Oedematous Pancreatitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Spironolactone; Furosemide; Allopurinol; Sodium Bicarbonate; Cozaar; Atorvastatin; Diltiazem
Possible Zemplar side effects in male
Reported by a physician from Germany on 2012-08-20
Patient: male, weighing 81.5 kg (179.3 pounds)
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Silapo; Torsemide; Bimatoprost and Timolol Maleate; Humalog; Dreisavit N; Propranolol; Huminsulin Basal; Iron (Ferrlecit); Calcium, Magnesium (Osvaren); Pantoprazole; Calcitriol; Diclofenac; Silapo; Allopurinol; Vitamin B-12
Possible Zemplar side effects in 64 year old female
Reported by a individual with unspecified qualification from United States on 2012-08-14
Patient: 64 year old female, weighing 70.3 kg (154.7 pounds)
Reactions: Vomiting, Diarrhoea, Nausea, Hypotension, Rhinorrhoea, Heart Rate Irregular, Decreased Appetite
Drug(s) suspected as cause:
Zemplar
Possible Zemplar side effects in male
Reported by a physician from Austria on 2012-08-14
Patient: male, weighing 50.0 kg (110.0 pounds)
Reactions: Emphysema, Hyperphosphataemia, Wheezing, General Physical Health Deterioration, Arrhythmia, Dyspnoea Exertional, Diarrhoea, Breath Sounds Abnormal, Hypocalcaemia, Urinary Retention, Splenic Calcification, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Sevelamer Hydrochloride
Administration route: Oral
Indication: Hyperphosphataemia
Start date: 2011-03-07
End date: 2012-06-07
Zemplar
Dosage: 2 x 2 cps per week
Indication: Hyperparathyroidism
Start date: 2012-02-06
End date: 2012-04-23
Zemplar
Dosage: 3 x 4 caps/week (monday, wednesday,friday)
Start date: 2012-04-23
End date: 2012-07-04
Other drugs received by patient: Aeromuc; Carvedilol; Trospium Chloride; Rocaltrol; Ferrlecit; Lasix; Calc Acet; Erypo; Carvedilol; Folsan; Maxi Kalz; CPS
Possible Zemplar side effects in male
Reported by a physician from United States on 2012-08-14
Patient: male, weighing 70.8 kg (155.8 pounds)
Reactions: Death, Cellulitis, Oedema Peripheral
Adverse event resulted in: death
Drug(s) suspected as cause:
Zemplar
Indication: Hyperparathyroidism Secondary
Zemplar
Indication: Renal Failure Chronic
Start date: 2010-09-01
End date: 2011-10-21
Other drugs received by patient: Clindamycin HCL; Acetaminophen; Triamcinolone Acetonide; NU-Iron; Imdur; Imdur; Metoprolol; Potassium Chloride; Nitroglycerin; Tamsulosin HCL; Bumex; Proscar; Levothyroxine Sodium; Warfarin Sodium; Multi-Vitamin; Warfarin Sodium; Paricalcitol; Metolazone; Digoxin
Possible Zemplar side effects in male
Reported by a physician from Austria on 2012-08-10
Patient: male, weighing 50.0 kg (110.0 pounds)
Reactions: Emphysema, Hyperphosphataemia, Wheezing, General Physical Health Deterioration, Arrhythmia, Dyspnoea Exertional, Breath Sounds Abnormal, Diarrhoea, Hypocalcaemia, Urinary Retention, Splenic Calcification, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Sevelamer Hydrochloride
Administration route: Oral
Indication: Hyperphosphataemia
Start date: 2011-03-07
End date: 2012-06-07
Zemplar
Dosage: 2 x 2 cps per week
Indication: Hyperparathyroidism
Start date: 2012-02-06
End date: 2012-04-23
Zemplar
Dosage: 3 x 4 caps/week (monday, wednesday,friday)
Start date: 2012-04-23
End date: 2012-07-04
Other drugs received by patient: Rocaltrol; Ferrlecit; Folsan; Lasix; Aeromuc; Carvedilol; CPS; Trospium Chloride; Maxi Kalz; Erypo; Calc Acet; Carvedilol
Possible Zemplar side effects in male
Reported by a physician from United States on 2012-08-09
Patient: male, weighing 69.5 kg (152.8 pounds)
Reactions: Chest Pain, Myocardial Infarction
Adverse event resulted in: death
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Unknown Beta Blockers; Metoprolol Tartrate; Several Other Medications
Possible Zemplar side effects in male
Reported by a physician from United States on 2012-08-08
Patient: male, weighing 69.5 kg (152.8 pounds)
Reactions: Chest Pain, Myocardial Infarction
Adverse event resulted in: death
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Metoprolol Tartrate; Unknown Beta Blockers; Several Other Medications
Possible Zemplar side effects in male
Reported by a physician from Austria on 2012-08-07
Patient: male, weighing 50.0 kg (110.0 pounds)
Reactions: Emphysema, Hyperphosphataemia, Wheezing, General Physical Health Deterioration, Arrhythmia, Dyspnoea Exertional, Diarrhoea, Breath Sounds Abnormal, Hypocalcaemia, Urinary Retention, Splenic Calcification, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Sevelamer Hydrochloride
Administration route: Oral
Indication: Hyperphosphataemia
Start date: 2011-03-07
End date: 2012-06-07
Zemplar
Dosage: 3 x 4 caps/week (monday, wednesday,friday)
Start date: 2012-04-23
End date: 2012-07-04
Zemplar
Dosage: 2 x 2 cps per week
Indication: Hyperparathyroidism
Start date: 2012-02-06
End date: 2012-04-23
Other drugs received by patient: Trospium Chloride; Rocaltrol; Calc Acet; Aeromuc; Renvela; CPS; Lasix; Maxi Kalz; Ferrlecit; Carvedilol; Carvedilol; Folsan; Erypo
Possible Zemplar side effects in male
Reported by a physician from Greece on 2012-08-06
Patient: male, weighing 55.0 kg (121.0 pounds)
Reactions: Bone Neoplasm Malignant, Dysphagia
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Calcium Carbonate; Amlodipine; Epoeitin-Alpha; Sevelamer; Atorvastatin; Amlodipine
Possible Zemplar side effects in male
Reported by a physician from Greece on 2012-08-04
Patient: male, weighing 68.0 kg (149.6 pounds)
Reactions: Angina Pectoris, Coronary Artery Occlusion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Ezetimibe; Tamsulosin HCL; Manyper; Hytrin; Allopurinol; Eprex; Imdur; Catapres; Plavix; Indapamide
Possible Zemplar side effects in 48 year old male
Reported by a physician from Germany on 2012-08-02
Patient: 48 year old male, weighing 113.0 kg (248.6 pounds)
Reactions: Parathyroidectomy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Possible Zemplar side effects in 40 year old male
Reported by a physician from Germany on 2012-08-02
Patient: 40 year old male
Reactions: Renal Transplant
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Possible Zemplar side effects in 82 year old female
Reported by a physician from Greece on 2012-08-01
Patient: 82 year old female
Reactions: Acute Pulmonary Oedema, Cardiac Failure, Renal Failure Chronic, Respiratory Tract Infection
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Plavix; Allopurinol; Adalat CC; Lipitor; Aranesp
Possible Zemplar side effects in 77 year old female
Reported by a physician from Germany on 2012-08-01
Patient: 77 year old female, weighing 59.5 kg (130.9 pounds)
Reactions: Femur Fracture, Fluid Retention
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Aranesp; Dekristol; Berodual; Calcet; Magnesium; Dreisavit; Metamizol; Heparin; Repaglinide; Fluticasone Propionate / Salmeterol; Torsemide; Spiriva; Spironolactone; Falithrom; Fluvastatin Sodium; Lyrica
Possible Zemplar side effects in 84 year old
Reported by a physician from Germany on 2012-08-01
Patient: 84 year old
Reactions: Dyspnoea Exertional, General Physical Health Deterioration, Coronary Artery Disease, Fall, Myocardial Infarction, Asthenia
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Erypo; Simvastatin; Frrlecit; Creon; Aspirin; Pantoprazole; Fosrenol
Possible Zemplar side effects in 47 year old male
Reported by a physician from Germany on 2012-08-01
Patient: 47 year old male, weighing 113.0 kg (248.6 pounds)
Reactions: Catheterisation Cardiac, Thyroid Neoplasm
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Possible Zemplar side effects in 47 year old male
Reported by a physician from Germany on 2012-08-01
Patient: 47 year old male, weighing 113.0 kg (248.6 pounds)
Reactions: Restless Legs Syndrome, Central Nervous System Lesion, Toxicity To Various Agents, Cerebellar Syndrome
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Dekristol
Possible Zemplar side effects in male
Reported by a physician from Germany on 2012-07-31
Patient: male, weighing 81.0 kg (178.2 pounds)
Reactions: Metastases To Central Nervous System, Convulsion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Ramipril; Epoetin Alfa; Ferrlecit; Metamizole; Metoprolol Tartrate; Omeprazole; Simvastatin
Possible Zemplar side effects in male
Reported by a physician from Austria on 2012-07-25
Patient: male, weighing 50.0 kg (110.0 pounds)
Reactions: Emphysema, Hyperphosphataemia, Wheezing, General Physical Health Deterioration, Arrhythmia, Dyspnoea Exertional, Breath Sounds Abnormal, Diarrhoea, Hypocalcaemia, Urinary Retention, Splenic Calcification, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Sevelamer
Administration route: Oral
Indication: Hyperphosphataemia
Start date: 2011-03-07
End date: 2012-06-07
Zemplar
Dosage: 3 x 4 caps/week (monday, wednesday,friday)
Start date: 2012-04-23
End date: 2012-07-04
Zemplar
Dosage: 2 x 2 cps per week
Indication: Hyperparathyroidism
Start date: 2012-02-06
End date: 2012-04-23
Other drugs received by patient: Lasix; Carvedilol; Maxi Kalz; Aeromuc; Carvedilol; Calc Acet; Calcitriol; CPS; Renvela; Erypo; Folsan; Rocaltrol; Spasmolyt Dragees; Ferrlecit
Possible Zemplar side effects in male
Reported by a physician from Greece on 2012-07-25
Patient: male, weighing 75.0 kg (165.0 pounds)
Reactions: Vertigo, Arteriovenous Fistula Thrombosis, Fall
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Bicalutamide
Administration route: Oral
Indication: Prostate Cancer
Start date: 2012-05-02
Zemplar
Indication: Hyperparathyroidism Secondary
Start date: 2012-01-04
Other drugs received by patient: Erythropoetin; Iron; Sevelamer; Triptorelin; L-Carnitine; Lantus; Calcium Carbonate
Possible Zemplar side effects in female
Reported by a physician from Germany on 2012-07-24
Patient: female, weighing 57.0 kg (125.4 pounds)
Reactions: Uterine Leiomyoma, Menorrhagia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Possible Zemplar side effects in 73 year old female
Reported by a physician from Austria on 2012-07-23
Patient: 73 year old female, weighing 78.0 kg (171.6 pounds)
Reactions: Respiratory Arrest, Cardiac Arrest
Adverse event resulted in: death
Drug(s) suspected as cause:
Zemplar
Dosage: 15mcg/week
Indication: Hyperparathyroidism Secondary
Start date: 2012-01-06
End date: 2012-02-29
Zemplar
Dosage: 10mcg/week
Start date: 2012-02-29
Other drugs received by patient: Nexium
Possible Zemplar side effects in 76 year old male
Reported by a physician from Germany on 2012-07-23
Patient: 76 year old male, weighing 96.0 kg (211.2 pounds)
Reactions: Diabetic Foot, Coronary Artery Disease
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Carenal; Aspirin; Xipamid; Torsemide; Nephrotrans; Ramipril
Possible Zemplar side effects in 71 year old male
Reported by a physician from Germany on 2012-07-23
Patient: 71 year old male
Reactions: Lymphostasis, Restless Legs Syndrome, Benign Prostatic Hyperplasia
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Isotret; Calciumacetat; Ferlecit; Torsemide
Possible Zemplar side effects in male
Reported by a physician from Germany on 2012-07-20
Patient: male, weighing 98.5 kg (216.7 pounds)
Reactions: Weight Decreased, Vomiting, Nausea, Intervertebral Discitis, Hypertension
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Buprenorphine
Dosage: 52 mcg per hour
Indication: Back Pain
Start date: 2011-12-23
Zemplar
Dosage: 5mcg on monday and friday after dialysis
Indication: Mesangioproliferative Glomerulonephritis
Start date: 2011-12-02
End date: 2012-01-23
Other drugs received by patient: Diclofenac; Concor; Pantoprazole; Abstral; Duragesic-100; Ferrlecit; Clindamycin; Aquaphor; Dekristol; Lercanidipine; Cefazolin; Carenal; Duragesic-100; Torsemide; Metoclopramide; Vergentan; Insuman; Allopurinol
Possible Zemplar side effects in female
Reported by a physician from Romania on 2012-07-19
Patient: female, weighing 55.0 kg (121.0 pounds)
Reactions: Renal Hypertension, Oedematous Pancreatitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zemplar
Other drugs received by patient: Spironolactone; Sodium Bicarbonate; Esomeprazole Magnesium; Furosemide; Esomeprazole Magnesium; Triferment; Allopurinol; Cozaar; Atorvastatin; Diltiazem; Triferment
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