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Zelboraf (Vemurafenib) - Fatigue - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Fatigue (182)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Zelboraf (Vemurafenib) where reactions include fatigue. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 182   Next >>

Possible Zelboraf side effects in 58 year old female

Reported by a physician from Sweden on 2012-08-24

Patient: 58 year old female, weighing 95.5 kg (210.1 pounds)

Reactions: Fatigue, Tumour Lysis Syndrome

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zelboraf
    Dosage: last dose prior to sae: 05/nov/2011
    Administration route: Oral
    Indication: Malignant Melanoma
    Start date: 2011-10-31

Zelboraf
    Administration route: Oral
    Start date: 2011-11-14

Zelboraf
    Start date: 2011-12-27

Zelboraf
    Start date: 2011-11-21
    End date: 2011-11-27

Zelboraf
    Start date: 2011-11-28
    End date: 2011-12-26

Other drugs received by patient: Acetaminophen; Metoclopramide; Xenical; Levotyroxin; Enoxaparin Natrium; Betametasona; Omeprazole



Possible Zelboraf side effects in male

Reported by a physician from Canada on 2012-08-23

Patient: male

Reactions: Fatigue, Pruritus, Mass, Arthralgia

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Zopiclone; Effexor; Ascorbic Acid; Lovaza; Vitamin D; Calcium; Oxycet



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-22

Patient: female

Reactions: Pruritus, Skin Reaction, Fall, Constipation, Fatigue, Arthropathy, Dizziness, Decreased Appetite, Blister, Cellulitis, Vomiting, Nausea, Squamous Cell Carcinoma, Skin Disorder, Rash, DRY Skin, Dysgeusia, Dysphonia, Diarrhoea, Arthralgia, Alopecia, Vision Blurred, Lacrimation Increased, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Motrin; Fexofenadine; Atorvastatin; Atenolol; Imodium



Possible Zelboraf side effects in 76 year old male

Reported by a pharmacist from United States on 2012-08-22

Patient: 76 year old male

Reactions: Fatigue, Depression, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in 54 year old female

Reported by a consumer/non-health professional from United States on 2012-08-22

Patient: 54 year old female

Reactions: Weight Decreased, Acne, Bone Pain, Muscular Weakness, Hemiparesis, Rash, Faeces Pale, Fatigue, Skin Ulcer, Sensory Disturbance, Squamous Cell Carcinoma of Skin

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-21

Patient: female, weighing 8.8 kg (19.4 pounds)

Reactions: Photosensitivity Reaction, Fatigue, Diarrhoea, Brain Oedema, Blood Creatinine Increased, Somnolence, Dermatitis Diaper

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf
    Administration route: Oral
    Indication: Malignant Melanoma
    Start date: 2011-10-12

Zelboraf
    Start date: 2011-11-03

Zelboraf
    Start date: 2012-05-10

Zelboraf
    Dosage: 120 mg in morning and 240 mg in evening
    Start date: 2011-12-07

Other drugs received by patient: Bactroban; Hydrocortisone; Prevacid



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-21

Patient: male

Reactions: Swelling Face, Fatigue, Mass, Rash Erythematous, Decreased Appetite, Disease Progression

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: male, weighing 66.7 kg (146.8 pounds)

Reactions: Bedridden, Nausea, Squamous Cell Carcinoma, Muscular Weakness, Atrial Fibrillation, DRY Skin, Sunburn, Adverse Reaction, Dysgeusia, Malaise, Fatigue, Skin Papilloma, Arthralgia, Swelling, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Decadron Phosphate



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: female, weighing 54.9 kg (120.9 pounds)

Reactions: Abasia, Rash, Fall, Anxiety, Fatigue, Dysstasia, Skin Papilloma, Arthralgia, Rash Erythematous, Feeling Hot, Mental Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Ativan



Possible Zelboraf side effects in female

Reported by a physician from United States on 2012-08-17

Patient: female, weighing 74.4 kg (163.7 pounds)

Reactions: Fatigue, Blood Uric Acid Increased, Hypotension, Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased, Rash Erythematous, Rash Macular

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf
    Dosage: last dose prior to sae 07 july 2011.
    Administration route: Oral
    Indication: Thyroid Cancer
    Start date: 2011-06-30
    End date: 2011-07-07

Zelboraf
    Administration route: Oral
    Start date: 2011-11-17
    End date: 2011-12-19

Zelboraf
    Administration route: Oral
    Start date: 2011-12-21
    End date: 2012-01-01

Zelboraf
    Dosage: dose modified due to an adverse event and then interrupted on 22 jul 2011 (reason not specified)
    Administration route: Oral
    Start date: 2011-07-14
    End date: 2011-07-22

Zelboraf
    Administration route: Oral
    Start date: 2011-10-14
    End date: 2011-10-20

Zelboraf
    Administration route: Oral
    Start date: 2011-10-24
    End date: 2011-11-12

Zelboraf
    Dosage: dose modified due to ae, then interrupted again (reason not specified)
    Administration route: Oral
    Start date: 2011-07-28
    End date: 2011-08-10

Zelboraf
    Administration route: Oral
    Start date: 2011-08-19
    End date: 2011-08-26

Zelboraf
    Administration route: Oral
    Start date: 2011-09-29
    End date: 2011-10-13

Zelboraf
    Administration route: Oral
    Start date: 2011-08-27
    End date: 2011-09-18

Zelboraf
    Administration route: Oral
    Start date: 2011-09-20
    End date: 2011-09-22

Zelboraf
    Administration route: Oral
    Start date: 2011-10-21
    End date: 2011-10-23

Zelboraf
    Administration route: Oral

Other drugs received by patient: Bifidobacterium; Ibuprofen; Nadolol; Synthroid; Norvasc; Codeine Sulfate; Citracal + D; Multi-Vitamin; Tramadol HCL; Ativan; Cholecalciferol; Ciclesonide; Aspirin; Probiotic Supplement NOS



Possible Zelboraf side effects in male

Reported by a physician from Canada on 2012-08-17

Patient: male

Reactions: Dysgeusia, Fatigue, Nasopharyngitis, Dehydration, Blood Creatinine Increased, Decreased Appetite, Paraesthesia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf
    Dosage: therapy restarted
    Administration route: Oral
    Start date: 2012-07-23

Zelboraf
    Administration route: Oral
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-01
    End date: 2012-06-13

Other drugs received by patient: Viagra; Crestor; Carvedilol; Teva-Amlodipine; Tylenol; Altace; Furosemide Teva; Metformin Hydrochloride



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from Canada on 2012-08-17

Patient: male

Reactions: Fatigue, Syncope, Nausea, Arthralgia, Hypotension, Sunburn

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Pantoprazole Sodium; Synthroid



Possible Zelboraf side effects in male

Reported by a physician from Belgium on 2012-08-14

Patient: male

Reactions: Dyspnoea, Hepatic Function Abnormal, Metabolic Acidosis, Hyperglycaemia, Hyponatraemia, Atrial Fibrillation, Cardiomegaly, Renal Failure, Fatigue

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Metformin HCL; Allopurinol; Allopurinol; Metformin HCL; Bisoprolol; CO-Bisoprolol; Simvastatin



Possible Zelboraf side effects in 58 year old female

Reported by a physician from Sweden on 2012-08-13

Patient: 58 year old female, weighing 95.5 kg (210.1 pounds)

Reactions: Tumour Lysis Syndrome, Fatigue

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zelboraf
    Dosage: last dose prior to sae: 05/nov/2011
    Administration route: Oral
    Indication: Malignant Melanoma
    Start date: 2011-10-31

Zelboraf
    Administration route: Oral
    Start date: 2011-11-14

Zelboraf
    Start date: 2011-11-21
    End date: 2011-11-27

Zelboraf
    Start date: 2011-11-28
    End date: 2011-12-26

Zelboraf
    Start date: 2011-12-27

Other drugs received by patient: Enoxaparin Natrium; Betametasona; Acetaminophen; Metoclopramide; Levotyroxin; Omeprazole; Xenical



Possible Zelboraf side effects in male

Reported by a physician from Canada on 2012-08-13

Patient: male

Reactions: Dysgeusia, Fatigue, Dehydration, Blood Creatinine Increased, Decreased Appetite, Paraesthesia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf
    Administration route: Oral
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-01
    End date: 2012-06-13

Zelboraf
    Dosage: therapy restarted

Other drugs received by patient: Tylenol; Furosemide Teva; Metformin Hydrochloride; Carvedilol; Teva-Amlodipine; Altace; Viagra; Crestor



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-10

Patient: female, weighing 77.2 kg (169.8 pounds)

Reactions: Adrenocortical Insufficiency Acute, Blood Cortisol Decreased, Sunburn, Myalgia, Fatigue, Arthralgia, Diarrhoea, Hiccups, Decreased Appetite, Blister

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Hydrocortisone; Fludrocortisone Acetate; Hydrocortisone



Possible Zelboraf side effects in female

Reported by a physician from United States on 2012-08-09

Patient: female, weighing 49.5 kg (108.9 pounds)

Reactions: Fatigue, Stomatitis, Nausea, Arthralgia, Vision Blurred, LIP Ulceration, Metastases To Central Nervous System

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Decadron Phosphate



Possible Zelboraf side effects in 58 year old female

Reported by a physician from Sweden on 2012-08-09

Patient: 58 year old female, weighing 95.5 kg (210.1 pounds)

Reactions: Fatigue, Tumour Lysis Syndrome

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zelboraf
    Dosage: last dose prior to sae: 05/nov/2011
    Administration route: Oral
    Indication: Malignant Melanoma
    Start date: 2011-10-31

Zelboraf
    Start date: 2011-11-28
    End date: 2011-12-26

Zelboraf
    Start date: 2011-12-27

Zelboraf
    Start date: 2011-11-21
    End date: 2011-11-27

Zelboraf
    Administration route: Oral
    Start date: 2011-11-14

Other drugs received by patient: Omeprazole; Metoclopramide; Betametasona; Enoxaparin Natrium; Levotyroxin; Xenical; Acetaminophen



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-07

Patient: female

Reactions: Skin Exfoliation, Hypotension, Rash, Hypoaesthesia, Eosinophil Count Increased, Joint Stiffness, Myalgia, Fatigue, Skin Papilloma, Arthralgia, Alopecia, Oedema, Decreased Appetite

Drug(s) suspected as cause:
Zelboraf
    Administration route: Oral
    Start date: 2012-07-30

Zelboraf
    Administration route: Oral
    Start date: 2012-07-01

Zelboraf
    Administration route: Oral
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-04
    End date: 2012-07-14

Other drugs received by patient: Hydrochlorothiazde TAB; Clonazepam; Norvasc; Dilaudid; Premarin; Zofran; Synthroid; Aspirin; Senokot; Tylenol; Crestor; Vitamin E; Atenolol



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-06

Patient: female, weighing 77.2 kg (169.8 pounds)

Reactions: Adrenocortical Insufficiency Acute, Blood Cortisol Decreased, Sunburn, Myalgia, Fatigue, Diarrhoea, Arthralgia, Hiccups, Blister, Decreased Appetite

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Fludrocortisone Acetate; Hydrocortisone



Possible Zelboraf side effects in female

Reported by a physician from United States on 2012-08-03

Patient: female, weighing 67.6 kg (148.8 pounds)

Reactions: Dysphagia, Vomiting, Nausea, Mass, Rash, Constipation, Fatigue, Oesophagitis, Alopecia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf
    Start date: 2012-03-16

Zelboraf
    Administration route: Oral
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-03-15

Other drugs received by patient: Dilaudid; Promethazine; Docusate Calcium; Zometa; Dukes Solution (Maalox, Benadryl, Viscous Xylocaine, Nystatin); Omeprazole; Carafate; Triamcinolone Acetonide; Desonide



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-03

Patient: male

Reactions: Vomiting, Squamous Cell Carcinoma, Nausea, Hypotension, Rash, Headache, Fatigue, Skin Papilloma, Diarrhoea, Chest Pain, Skin Mass, Melanocytic Naevus, Blood Creatinine Increased, Adrenal Disorder, Decreased Appetite

Drug(s) suspected as cause:
Ipilimumab
    Indication: Metastatic Malignant Melanoma

Zelboraf
    Dosage: unknown
    Administration route: Oral
    Indication: Metastatic Malignant Melanoma
    Start date: 2011-08-01



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-31

Patient: male

Reactions: Weight Decreased, Vomiting, Squamous Cell Carcinoma, Nausea, Mass, Headache, Sunburn, Dysgeusia, Death, Fatigue, Alopecia

Adverse event resulted in: death

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-30

Patient: female

Reactions: Pruritus, Nausea, Mass, Skin Exfoliation, Chills, Rash, Pyrexia, Headache, Eye Pain, Hepatic Neoplasm, Myalgia, Fatigue, Dysphonia, Arthralgia, Ocular Hyperaemia, Alopecia, Vision Blurred

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in 58 year old female

Reported by a physician from Sweden on 2012-07-30

Patient: 58 year old female, weighing 95.5 kg (210.1 pounds)

Reactions: Tumour Lysis Syndrome, Fatigue

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zelboraf
    Dosage: last dose prior to sae: 05/nov/2011
    Administration route: Oral
    Indication: Malignant Melanoma
    Start date: 2011-10-31

Zelboraf
    Administration route: Oral
    Start date: 2011-11-14

Zelboraf
    Start date: 2011-12-27

Zelboraf
    Start date: 2011-11-21
    End date: 2011-11-27

Zelboraf
    Start date: 2011-11-28
    End date: 2011-12-26

Other drugs received by patient: Omeprazole; Levotyroxin; Betametasona; Xenical; Enoxaparin Natrium; Acetaminophen; Metoclopramide



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-30

Patient: female

Reactions: Rash Pustular, Nausea, Rash, Disease Progression, Sunburn, Dysgeusia, Fatigue, Diarrhoea

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-26

Patient: male, weighing 88.1 kg (193.8 pounds)

Reactions: Pruritus, Pain in Extremity, Drug Ineffective, Rash, Neoplasm, Adverse Reaction, Sunburn, Herpes Zoster, Myalgia, Fatigue, Skin Papilloma, Diarrhoea, Arthralgia, Alopecia, Skin Mass

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-23

Patient: male

Reactions: Pruritus, Nausea, Mass, Erythema, Sunburn, Dysgeusia, Fatigue, Chest Pain, Alopecia, Pulmonary Thrombosis, Asthenia, Blister

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-20

Patient: male, weighing 83.1 kg (182.8 pounds)

Reactions: Nasopharyngitis, Pain in Extremity, Mass, Squamous Cell Carcinoma, Rash, Constipation, Plantar Fasciitis, Dysgeusia, Fatigue, Arthralgia, Alopecia, Feeling Abnormal, Decreased Appetite

Drug(s) suspected as cause:
Zelboraf
    Administration route: Oral
    Indication: Malignant Melanoma Stage IV
    Start date: 2012-02-09

Zelboraf
    Administration route: Oral
    Start date: 2012-02-19

Other drugs received by patient: Aspirin; Simvastatin; Terazosin HCL; Ascorbic Acid; Prednisone; Hytrin; Imdur; Metoprolol Succinate



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-20

Patient: male

Reactions: Myalgia, Fatigue, Arthralgia, Nausea, Pancreatitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf



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