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Zelboraf (Vemurafenib) - Arthralgia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Arthralgia (174)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Zelboraf (Vemurafenib) where reactions include arthralgia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 174   Next >>

Possible Zelboraf side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-23

Patient: female

Reactions: Arthralgia, Cystitis, Rash, Headache

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a physician from Canada on 2012-08-23

Patient: male

Reactions: Fatigue, Pruritus, Mass, Arthralgia

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Zopiclone; Effexor; Ascorbic Acid; Lovaza; Vitamin D; Calcium; Oxycet



Possible Zelboraf side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-22

Patient: female, weighing 60.8 kg (133.8 pounds)

Reactions: Madarosis, Swelling Face, Pruritus, Mass, Skin Exfoliation, Chills, Rash, Erythema, Myalgia, Pericarditis, Arthralgia, Alopecia, Rash Erythematous

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf
    Start date: 2012-06-11

Zelboraf
    Start date: 2012-02-01

Zelboraf
    Dosage: therapy for 36 days

Zelboraf
    Administration route: Oral
    Indication: Malignant Melanoma
    Start date: 2011-12-26
    End date: 2012-01-04



Possible Zelboraf side effects in female

Reported by a physician from Canada on 2012-08-22

Patient: female

Reactions: Pruritus, Squamous Cell Carcinoma, Pain in Extremity, Urticaria, Pyrexia, DRY Skin, Erythema, Eye Pain, Myalgia, Arthralgia, Alopecia, Memory Impairment, DRY Eye, Sinusitis

Drug(s) suspected as cause:
Zelboraf
    Administration route: Oral
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-04-19

Zelboraf
    Dosage: dose reduced.
    Administration route: Oral
    Start date: 2012-05-01

Other drugs received by patient: Ativan; Vitamin D; COQ-10; Minocycline HCL; Multi-Vitamins; Potassium; Hydrocortisone; Coral Calcium; Shark Liver OIL; Benadryl



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-22

Patient: female

Reactions: Pruritus, Skin Reaction, Fall, Constipation, Fatigue, Arthropathy, Dizziness, Decreased Appetite, Blister, Cellulitis, Vomiting, Nausea, Squamous Cell Carcinoma, Skin Disorder, Rash, DRY Skin, Dysgeusia, Dysphonia, Diarrhoea, Arthralgia, Alopecia, Vision Blurred, Lacrimation Increased, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Motrin; Fexofenadine; Atorvastatin; Atenolol; Imodium



Possible Zelboraf side effects in female

Reported by a pharmacist from United States on 2012-08-20

Patient: female

Reactions: White Blood Cell Count Decreased, Arthralgia, Rash

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: male, weighing 66.7 kg (146.8 pounds)

Reactions: Bedridden, Nausea, Squamous Cell Carcinoma, Muscular Weakness, Atrial Fibrillation, DRY Skin, Sunburn, Adverse Reaction, Dysgeusia, Malaise, Fatigue, Skin Papilloma, Arthralgia, Swelling, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Decadron Phosphate



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: female, weighing 54.9 kg (120.9 pounds)

Reactions: Abasia, Rash, Fall, Anxiety, Fatigue, Dysstasia, Skin Papilloma, Arthralgia, Rash Erythematous, Feeling Hot, Mental Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Ativan



Possible Zelboraf side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-17

Patient: female

Reactions: Arthralgia, Headache, Rash, Cystitis

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from Canada on 2012-08-17

Patient: male

Reactions: Fatigue, Syncope, Nausea, Arthralgia, Hypotension, Sunburn

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Pantoprazole Sodium; Synthroid



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-15

Patient: female, weighing 60.8 kg (133.8 pounds)

Reactions: Madarosis, Pruritus, Swelling Face, Mass, Skin Exfoliation, Chills, Erythema, Myalgia, Pericarditis, Arthralgia, Alopecia, Rash Erythematous

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf
    Administration route: Oral
    Indication: Malignant Melanoma
    Start date: 2011-12-26
    End date: 2012-01-04

Zelboraf
    Start date: 2012-06-11
    End date: 2012-06-26

Zelboraf
    Start date: 2012-02-01

Zelboraf
    Dosage: therapy for 36 days

Other drugs received by patient: Steroids - Unknown Type



Possible Zelboraf side effects in male

Reported by a pharmacist from United States on 2012-08-10

Patient: male

Reactions: Chills, Recurrent Cancer, Rash, DRY Skin, Pyrexia, Diarrhoea, Arthralgia, Squamous Cell Carcinoma of Skin

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-10

Patient: female, weighing 77.2 kg (169.8 pounds)

Reactions: Adrenocortical Insufficiency Acute, Blood Cortisol Decreased, Sunburn, Myalgia, Fatigue, Arthralgia, Diarrhoea, Hiccups, Decreased Appetite, Blister

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Hydrocortisone; Fludrocortisone Acetate; Hydrocortisone



Possible Zelboraf side effects in female

Reported by a physician from United States on 2012-08-09

Patient: female, weighing 49.5 kg (108.9 pounds)

Reactions: Fatigue, Stomatitis, Nausea, Arthralgia, Vision Blurred, LIP Ulceration, Metastases To Central Nervous System

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Decadron Phosphate



Possible Zelboraf side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-07

Patient: female

Reactions: Back Pain, Vomiting, Squamous Cell Carcinoma, Nausea, Keratoacanthoma, Oesophagitis, Arthralgia, Rash Erythematous, Swelling, Dehydration, Oedema Peripheral, Neutropenia, Melanocytic Naevus, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Xanax; Omeprazole; Docusate Calcium; Cholecalciferol; Carafate; Iron Sulfatethiamin Compound TAB; Dukes Solution (Benadryl, Maalox, Viscous Xylocaine, Nystatin)



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-07

Patient: female

Reactions: Skin Exfoliation, Hypotension, Rash, Hypoaesthesia, Eosinophil Count Increased, Joint Stiffness, Myalgia, Fatigue, Skin Papilloma, Arthralgia, Alopecia, Oedema, Decreased Appetite

Drug(s) suspected as cause:
Zelboraf
    Administration route: Oral
    Start date: 2012-07-30

Zelboraf
    Administration route: Oral
    Start date: 2012-07-01

Zelboraf
    Administration route: Oral
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-04
    End date: 2012-07-14

Other drugs received by patient: Hydrochlorothiazde TAB; Clonazepam; Norvasc; Dilaudid; Premarin; Zofran; Synthroid; Aspirin; Senokot; Tylenol; Crestor; Vitamin E; Atenolol



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-06

Patient: female, weighing 77.2 kg (169.8 pounds)

Reactions: Adrenocortical Insufficiency Acute, Blood Cortisol Decreased, Sunburn, Myalgia, Fatigue, Diarrhoea, Arthralgia, Hiccups, Blister, Decreased Appetite

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Fludrocortisone Acetate; Hydrocortisone



Possible Zelboraf side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-30

Patient: female, weighing 99.1 kg (218.0 pounds)

Reactions: Renal Failure, Arthralgia, Diarrhoea, Pancreatitis, Pyrexia, Rash

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Clonidine; Exforge; Colace; Metoprolol Tartrate; Potassium Chloride; Valtrex; Hydrochlorothiazide; Metformin Hydrochloride; Prilosec; Glipizide



Possible Zelboraf side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-30

Patient: female

Reactions: Pruritus, Nausea, Mass, Skin Exfoliation, Chills, Rash, Pyrexia, Headache, Eye Pain, Hepatic Neoplasm, Myalgia, Fatigue, Dysphonia, Arthralgia, Ocular Hyperaemia, Alopecia, Vision Blurred

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-26

Patient: male, weighing 88.1 kg (193.8 pounds)

Reactions: Pruritus, Pain in Extremity, Drug Ineffective, Rash, Neoplasm, Adverse Reaction, Sunburn, Herpes Zoster, Myalgia, Fatigue, Skin Papilloma, Diarrhoea, Arthralgia, Alopecia, Skin Mass

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-20

Patient: male, weighing 83.1 kg (182.8 pounds)

Reactions: Nasopharyngitis, Pain in Extremity, Mass, Squamous Cell Carcinoma, Rash, Constipation, Plantar Fasciitis, Dysgeusia, Fatigue, Arthralgia, Alopecia, Feeling Abnormal, Decreased Appetite

Drug(s) suspected as cause:
Zelboraf
    Administration route: Oral
    Indication: Malignant Melanoma Stage IV
    Start date: 2012-02-09

Zelboraf
    Administration route: Oral
    Start date: 2012-02-19

Other drugs received by patient: Aspirin; Simvastatin; Terazosin HCL; Ascorbic Acid; Prednisone; Hytrin; Imdur; Metoprolol Succinate



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-20

Patient: male

Reactions: Myalgia, Fatigue, Arthralgia, Nausea, Pancreatitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-18

Patient: male

Reactions: Weight Decreased, Acrochordon, Nausea, Squamous Cell Carcinoma, Rash, Neoplasm, Sunburn, Disease Progression, Fatigue, Arthralgia, Rash Erythematous, Melanocytic Naevus, Asthenia, Decreased Appetite

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-18

Patient: female

Reactions: Pruritus, Skin Exfoliation, Chills, Headache, Pyrexia, Myalgia, Fatigue, Nausea, Mass, Rash, Eye Pain, Hepatic Neoplasm, Dysphonia, Arthralgia, Ocular Hyperaemia, Alopecia, Vision Blurred

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in 63 year old male

Reported by a pharmacist from United States on 2012-07-11

Patient: 63 year old male

Reactions: Arthralgia, Bone Pain, Rash

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in 69 year old male

Reported by a physician from Germany on 2012-07-09

Patient: 69 year old male

Reactions: Skin Papilloma, Arthralgia, Rash, Conjunctival Disorder, Erythema

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-09

Patient: male, weighing 96.7 kg (212.7 pounds)

Reactions: Pruritus, Nasopharyngitis, Skin Exfoliation, Neoplasm, Erythema, Myalgia, Fatigue, Neuropathy Peripheral, Sinus Congestion, Decreased Appetite, Muscle Spasms, Squamous Cell Carcinoma, Nausea, Skin Papilloma, Diarrhoea, Arthralgia

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Ativan; SAW Palmetto; Celexa; Klonopin; Hydrocodone Bitartrate + Acetaminophen; Toprol-XL; Shark Cartilage; Omeprazole; Ferrous Fumarate



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-09

Patient: male

Reactions: Pruritus, Squamous Cell Carcinoma, Mass, Headache, Erythema, Dysgeusia, Fatigue, Arthralgia, DRY Mouth, Visual Impairment, Dizziness

Drug(s) suspected as cause:
Zelboraf



Possible Zelboraf side effects in female

Reported by a physician from United Kingdom on 2012-07-05

Patient: female, weighing 57.1 kg (125.6 pounds)

Reactions: Confusional State, Unresponsive To Stimuli, Abasia, Pyrexia, Fatigue, Hiccups, Oedema Mouth, Feeling of Body Temperature Change, Depression, Decreased Appetite, Vomiting, Nausea, Hypotension, Musculoskeletal Pain, Rash, Arthralgia, Joint Swelling, Alopecia, Visual Impairment, Petit MAL Epilepsy, Mobility Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Metoclopramide; Losartan Potassium; Doxazosin Mesylate



Possible Zelboraf side effects in male

Reported by a consumer/non-health professional from United States on 2012-06-26

Patient: male

Reactions: Weight Decreased, Skin Exfoliation, Pain of Skin, DRY Skin, Rash, Sunburn, Abdominal Discomfort, Skin Papilloma, Fatigue, Arthralgia, Neoplasm Skin, Ageusia, Insomnia, Alopecia, Hair Growth Abnormal, Decreased Appetite

Drug(s) suspected as cause:
Zelboraf

Other drugs received by patient: Selenium; Krill OIL; COQ-10



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