Index of reports
> Cases with Neutropenia (25)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Vinorelbine where reactions include neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Vinorelbine side effects in
Reported by a physician from United States on 2012-07-06
Patient:
Reactions: Respiratory Failure, Anaemia, Neutropenia, Thrombocytopenia, Infection
Drug(s) suspected as cause:
Doxorubicin Hydrochloride
Dosage: administered on day 1 and day 8 of every 21 day cycle
Indication: Diffuse Large B-Cell Lymphoma
Vinorelbine
Dosage: administered on day 1 and day 8 of every 21 day cycle
Indication: Diffuse Large B-Cell Lymphoma
Colony Stimulating Factor
Dosage: on day 9 of each cycle
Indication: Diffuse Large B-Cell Lymphoma
Rituximab
Dosage: administered on day 1 and day 8 of every 21 day cycle
Indication: Diffuse Large B-Cell Lymphoma
Gemcitabine
Dosage: administered on day 1 and day 8 of every 21 day cycle
Indication: Diffuse Large B-Cell Lymphoma
Possible Vinorelbine side effects in 20 year old female
Reported by a physician from Taiwan, Province of China on 2012-07-02
Patient: 20 year old female
Reactions: Refusal of Treatment by Patient, Hepatic Function Abnormal, Mental Status Changes, Disorientation, Respiratory Alkalosis, Somnolence, Convulsion, Hyperammonaemia, Depressed Level of Consciousness, Neutropenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Vinorelbine
Dosage: 20 mg/m**2;qd;
Indication: B Precursor Type Acute Leukaemia
Gemcitabine Hydrochloride
Dosage: 10 mg/m**2;
Indication: B Precursor Type Acute Leukaemia
Other drugs received by patient: Vincristine; Cytarabine; Dexamethasone; Doxorubicin HCL; Asparaginase; Thiotepa; Mitoxantrone; Topotecan; Cisplatin
Possible Vinorelbine side effects in female
Reported by a physician from Chile on 2012-06-29
Patient: female, weighing 74.5 kg (163.9 pounds)
Reactions: Neutropenia
Drug(s) suspected as cause:
Lapatinib
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer Metastatic
Start date: 2012-02-03
Vinorelbine
Dosage: 20mgm2 cyclic
Indication: Breast Cancer Metastatic
Start date: 2012-02-03
Possible Vinorelbine side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-27
Patient:
Reactions: Respiratory Failure, Anaemia, Neutropenia, Thrombocytopenia, Infection
Drug(s) suspected as cause:
Vinorelbine
Dosage: administered on day 1 and day 8 of every 21 day cycle
Indication: Diffuse Large B-Cell Lymphoma
Doxorubicin Hydrochloride
Dosage: administered on day 1 and day 8 of every 21 day cycle
Indication: Diffuse Large B-Cell Lymphoma
Rituximab
Dosage: administered on day 1 and day 8 of every 21 day cycle
Indication: Diffuse Large B-Cell Lymphoma
Gemcitabine
Dosage: administered on day 1 and day 8 of every 21 day cycle
Indication: Diffuse Large B-Cell Lymphoma
Colony Stimulating Factor
Dosage: on day 9 of each cycle
Indication: Diffuse Large B-Cell Lymphoma
Possible Vinorelbine side effects in 39 year old female
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-06-22
Patient: 39 year old female
Reactions: Abdominal Pain, Alanine Aminotransferase Increased, Wrong Drug Administered, Accidental Overdose, Ileus Paralytic, Abdominal Pain Upper, Neurotoxicity, Myalgia, Hepatotoxicity, Diarrhoea, Colitis, Neutropenia, Thrombocytopenia, Leukopenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Vinorelbine
Dosage: 35 mg, unk
Indication: Hodgkin's Disease
Vinblastine Sulfate
Dosage: 35 mg, unk
Other drugs received by patient: Prednisolone; Ifosfamide; Gemcitabine
Possible Vinorelbine side effects in
Reported by a physician from United States on 2012-06-22
Patient:
Reactions: Thrombosis, Device Related Infection, Headache, Peripheral Sensory Neuropathy, Pericardial Effusion, Malaise, Dyspepsia, Granulocytopenia, Hypoxia, Pneumonitis, Blood Alkaline Phosphatase Increased, Hyperglycaemia, Anaemia, Hypotension, Dehydration, Neutropenia, Bone Pain, Pain, Hypokalaemia, Disease Progression, Death, Postoperative Wound Infection, Fatigue, Neutropenic Infection, Chest Pain, Depression, Lethargy, Vomiting, Dyspnoea, Alanine Aminotransferase Increased, Lymphopenia, Muscular Weakness, Febrile Neutropenia, Hypophosphataemia, Syncope, Diarrhoea, Arthralgia, Ejection Fraction Decreased, Hypermagnesaemia, Respiratory Tract Infection, Leukopenia, Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Docetaxel
Dosage: 60 mg/m2, unk
Indication: Breast Cancer Metastatic
Vinorelbine
Dosage: 27.5 mg/m2, per chemo regim
Indication: Breast Cancer Metastatic
Filgrastim
Dosage: 5 mug/kg, per chemo regim
Indication: Breast Cancer Metastatic
Trastuzumab
Dosage: 2 mg/kg, qwk
Trastuzumab
Dosage: 4 mg/kg, one time dose
Indication: Breast Cancer Metastatic
Possible Vinorelbine side effects in 76 year old female
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-05-25
Patient: 76 year old female
Reactions: Hyperbilirubinaemia, Dyspnoea, Neutropenia
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Cisplatin
Indication: non-Small Cell Lung Cancer
Start date: 2005-06-16
Cetuximab
Dosage: 2nd inf on
Indication: non-Small Cell Lung Cancer
Start date: 2005-06-16
Vinorelbine
Indication: non-Small Cell Lung Cancer
Start date: 2005-06-16
Possible Vinorelbine side effects in 48 year old female
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-05-21
Patient: 48 year old female
Reactions: Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cisplatin
Dosage: last dose:12jul2005
Indication: non-Small Cell Lung Cancer
Start date: 2005-05-30
Vinorelbine
Indication: non-Small Cell Lung Cancer
Start date: 2005-05-30
Possible Vinorelbine side effects in 61 year old female
Reported by a consumer/non-health professional from Germany on 2012-03-22
Patient: 61 year old female, weighing 45.0 kg (99.0 pounds)
Reactions: Neutropenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Cisplatin
Dosage: 100mg:16feb10-10mar10, 35mg:09apr10-09apr10.
Indication: non-Small Cell Lung Cancer
Start date: 2010-02-16
End date: 2010-04-09
Cetuximab
Dosage: 09feb10-09feb10,(77.1429mg) 16feb10-21may10.(340mg,1 in 1 week).
Indication: non-Small Cell Lung Cancer
Start date: 2010-02-09
End date: 2010-05-21
Vinorelbine
Dosage: 33mg:16feb10-26mar10, 17mg:09apr10-21apr10.
Indication: non-Small Cell Lung Cancer
Start date: 2010-02-16
End date: 2010-04-21
Possible Vinorelbine side effects in 46 year old female
Reported by a consumer/non-health professional from Germany on 2012-03-21
Patient: 46 year old female, weighing 62.0 kg (136.4 pounds)
Reactions: Neutropenia, Leukopenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Cisplatin
Dosage: 131mgd1:17jul10-07aug10, 44mg,d1-3:08sep10-22sep10-ong.
Indication: non-Small Cell Lung Cancer
Start date: 2010-07-17
Cetuximab
Dosage: cetuximab intravenous infusion 435mg:17jul10-22oct10-ong
Indication: non-Small Cell Lung Cancer
Start date: 2010-07-10
Vinorelbine
Dosage: 44mg,d1 d8:17jul10-13aug10(27 days) 22mg,d1 d8:08sep10--22oct10 ong.
Indication: non-Small Cell Lung Cancer
Start date: 2010-07-17
Possible Vinorelbine side effects in 57 year old male
Reported by a consumer/non-health professional from Germany on 2012-03-21
Patient: 57 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Neutropenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Cetuximab
Dosage: 07nov09-07nov09,13nov09-27nov09;14d;430mg,04dec09-05feb10;63d;400mg,intravenous infusion
Indication: non-Small Cell Lung Cancer
Start date: 2009-11-07
End date: 2010-02-05
Cisplatin
Dosage: 13nov09-13nov09;d1,d8,04dec09-04dec09;108mg;d1,d8,30dec09-22jan10;23days;35mg;d1,8
Indication: non-Small Cell Lung Cancer
Start date: 2009-11-13
End date: 2010-01-22
Vinorelbine
Dosage: 13nov09-20nov09;7d;d1,d8,04dec09-unk;34mg;d1,8,30dec09-29jan10;22mg;30d;d1,8
Indication: non-Small Cell Lung Cancer
Start date: 2009-11-13
End date: 2010-01-29
Possible Vinorelbine side effects in 63 year old male
Reported by a consumer/non-health professional from Germany on 2012-03-21
Patient: 63 year old male, weighing 65.0 kg (143.0 pounds)
Reactions: Bone Marrow Failure, Neutropenia, Leukopenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Vinorelbine
Dosage: last 19nov10.and continued.infusion. 40mg from 3sep10-30sep10(77d) 20mg from 21oct10-19nov10(77d)
Indication: non-Small Cell Lung Cancer
Start date: 2010-09-03
End date: 2010-11-19
Cisplatin
Dosage: last 12nov10.and continued 120mg from 3sep10 - 24sep10(21d) 40mg from 21oct10 - 12nov10(70d)
Indication: non-Small Cell Lung Cancer
Start date: 2010-09-03
End date: 2010-11-12
Cetuximab
Dosage: last dose:3dec10.and continued initial dose:640mg on 27aug10 03sep-03dec10
Indication: non-Small Cell Lung Cancer
Start date: 2010-08-27
End date: 2010-12-03
Possible Vinorelbine side effects in 57 year old male
Reported by a consumer/non-health professional from Germany on 2012-03-21
Patient: 57 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Neutropenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Cetuximab
Dosage: 7nov09-7nov09=692mg,13nov09-27nov09=430mg,04dec09-5feb2010(400mg 1 in 1 week).
Indication: non-Small Cell Lung Cancer
Start date: 2009-11-07
End date: 2010-02-05
Vinorelbine
Dosage: 13nov09-20nov09,d1,8,04dec- 34mg every 3 week d,1,8,30dec09- 22mgevery 3weeks d,1,8
Indication: non-Small Cell Lung Cancer
Start date: 2009-11-13
End date: 2010-01-29
Cisplatin
Dosage: 13nov09-13nov09,d1,4dec09-4dec09=108mg every 3week d1,30dec09- 35 mg every 3weeksd1,
Indication: non-Small Cell Lung Cancer
Start date: 2009-11-13
End date: 2010-01-22
Possible Vinorelbine side effects in 49 year old male
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-21
Patient: 49 year old male, weighing 55.0 kg (121.0 pounds)
Reactions: Neutropenia, Leukopenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Vinorelbine
Dosage: inter on 13jul11 initial dose:40 mg frm 03may11 - 31may11 20mg frm 15jun11 - 13jul11
Indication: non-Small Cell Lung Cancer
Start date: 2011-05-03
Cetuximab
Dosage: inter on 20jul11,iv infusion initial dose:640 mg on 25apr11 400mg frm 03may11 - 20jul11
Indication: non-Small Cell Lung Cancer
Start date: 2011-04-25
Cisplatin
Dosage: inter on 06jul11 initial dose:120 mg on 03may11 - 24may11 iv 40mg frm 15jun11 - 06jul11 iv drip
Indication: non-Small Cell Lung Cancer
Start date: 2011-05-03
Possible Vinorelbine side effects in 68 year old male
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-03-21
Patient: 68 year old male, weighing 65.0 kg (143.0 pounds)
Reactions: Neutropenia, Leukopenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Vinorelbine
Dosage: 43mg d1,d8,q3w 20mg d1,d8,q3w 29jun10-8jul10;9d 21jul-29jul1:34mg 8d 21aug-1sep10:20mg 29d
Indication: non-Small Cell Lung Cancer
Start date: 2010-06-29
Cetuximab
Dosage: cetuximab intravenous infusion 23jun10 29jun10-15sep10;78d (437 mg)
Indication: non-Small Cell Lung Cancer
Start date: 2010-06-23
Cisplatin
Dosage: 130mg q3w 40mg d1-d3 q3w 29jun10:130 mg;1d 21jul10-104mg 11aug10-1sep10:40mg 21d
Indication: non-Small Cell Lung Cancer
Start date: 2010-06-29
Possible Vinorelbine side effects in 59 year old female
Reported by a consumer/non-health professional from Germany on 2012-03-20
Patient: 59 year old female, weighing 65.0 kg (143.0 pounds)
Reactions: Neutropenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Cetuximab
Dosage: stat,inter on 30jul10,25jun10, 20jul10iv.625mg stat 14-14may10;400mgqw21may-25jun10. last 30jul10
Indication: non-Small Cell Lung Cancer
Start date: 2010-05-14
Vinorelbine
Dosage: frequency:stat,inter on 30jul10,therapy duration:70days 40mg d1,d8,21may2010
Indication: non-Small Cell Lung Cancer
Start date: 2010-03-21
Cisplatin
Dosage: stat,inter on 30jul10,therapy duration:70days. 120mg 21may-12jun10 44mg 5-30jul10 d1 d3 3wks
Indication: non-Small Cell Lung Cancer
Start date: 2010-05-21
Possible Vinorelbine side effects in 52 year old male
Reported by a consumer/non-health professional from Germany on 2012-03-20
Patient: 52 year old male, weighing 50.0 kg (110.0 pounds)
Reactions: non-Small Cell Lung Cancer, Bone Marrow Failure, Neoplasm Progression, Neutropenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Cetuximab
Dosage: 05-05jul11(630mg),12jul11-unk (394mg)56.2857 mg,09aug11-16aug11 (350mg)d1qw 50mg,no of cycles:2
Indication: non-Small Cell Lung Cancer
Start date: 2011-07-05
Vinorelbine
Dosage: d1,d8,12jul11-19jul11(7days),09aug11-16aug11 1.4286mg(30mg),no of cycles:2
Indication: non-Small Cell Lung Cancer
Start date: 2011-07-12
Cisplatin
Dosage: 12jul2011-12jul11:118mg d1 qw,09aug11-09aug11(1day) 4.2857 mg(90mg),no of cycles:2
Indication: non-Small Cell Lung Cancer
Start date: 2011-07-12
Possible Vinorelbine side effects in 67 year old male
Reported by a health professional (non-physician/pharmacist) from China on 2012-03-14
Patient: 67 year old male
Reactions: Death, Hepatic Function Abnormal, Neutropenia
Adverse event resulted in: death
Drug(s) suspected as cause:
Cisplatin
Indication: Squamous Cell Carcinoma
Vinorelbine
Indication: Squamous Cell Carcinoma
Other drugs received by patient: Cetuximab; Cetuximab
Possible Vinorelbine side effects in
Reported by a physician from United States on 2012-01-31
Patient:
Reactions: Death, Fatigue, Neutropenia, Disease Progression, Leukopenia
Adverse event resulted in: death
Drug(s) suspected as cause:
Trastuzumab
Dosage: 2 mg/kg, qwk
Filgrastim
Dosage: 5 mug/kg, per chemo regim
Indication: Breast Cancer Metastatic
Vinorelbine
Dosage: 27.5 mg, per chemo regim
Indication: Breast Cancer Metastatic
Trastuzumab
Dosage: 4 mg/kg, one time dose
Indication: Breast Cancer Metastatic
Docetaxel
Dosage: 60 mg, one time dose
Indication: Breast Cancer Metastatic
Possible Vinorelbine side effects in female
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-01-17
Patient: female
Reactions: Neutropenia, Hypertransaminasaemia
Drug(s) suspected as cause:
Herceptin
Indication: Breast Cancer
Start date: 2011-10-19
Herceptin
Start date: 2011-10-19
Zometa
Indication: Breast Cancer
Start date: 2011-10-19
Vinorelbine
Indication: Product Used FOR Unknown Indication
Start date: 2011-10-19
Other drugs received by patient: Olmesartan Medoxomil
Possible Vinorelbine side effects in
Reported by a physician from United States on 2012-01-11
Patient:
Reactions: Fatigue, Neutropenia, Leukopenia
Drug(s) suspected as cause:
Vinorelbine
Dosage: 27.5 mg, per chemo regim
Indication: Breast Cancer Metastatic
Docetaxel
Dosage: 60 mg, one time dose
Indication: Breast Cancer Metastatic
Trastuzumab
Dosage: 4 mg/kg, one time dose
Indication: Breast Cancer Metastatic
Trastuzumab
Dosage: 2 mg/kg, qwk
Neupogen
Dosage: 5 mug/kg, per chemo regim
Indication: Breast Cancer Metastatic
Possible Vinorelbine side effects in 49 year old female
Reported by a physician from United States on 2012-01-09
Patient: 49 year old female, weighing 105.5 kg (232.1 pounds)
Reactions: Dehydration, Neutropenia, Renal Failure Acute
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Lapatinib
Dosage: 1500mg per day
Administration route: Oral
Indication: Breast Cancer Metastatic
Start date: 2011-04-07
Vinorelbine
Dosage: 20mgm2 cyclic
Indication: Breast Cancer Metastatic
Start date: 2011-04-07
Diovan
Dosage: 40mg per day
Administration route: Oral
Indication: Hypertension
Start date: 2007-01-01
End date: 2011-04-20
Lisinopril
Dosage: 10mg per day
Administration route: Oral
Indication: Hypertension
Start date: 2007-01-01
End date: 2011-04-20
Possible Vinorelbine side effects in female
Reported by a health professional (non-physician/pharmacist) from Italy on 2011-11-16
Patient: female
Reactions: Neutropenia, Hypertransaminasaemia
Drug(s) suspected as cause:
Zometa
Dosage: 4 mg, (cyclic)
Indication: Osteoporosis Prophylaxis
Start date: 2011-05-06
Vinorelbine
Dosage: 49 mg,(cyclic)
Indication: Breast Cancer
Start date: 2011-05-06
Other drugs received by patient: Telmisartan and Hydrochlorothiazide
Possible Vinorelbine side effects in 59 year old
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-11-01
Patient: 59 year old
Reactions: Sepsis, Neutropenia, Toxicity To Various Agents
Adverse event resulted in: death, disablity
Drug(s) suspected as cause:
Anthracycline (NO Pref. Name)
Indication: Breast Cancer Metastatic
Capecitabine
Indication: Breast Cancer Metastatic
Trastuzumab (Trastuzumab)
Indication: Breast Cancer Metastatic
5-HT3 (NO Pref. Name)
Indication: Breast Cancer Metastatic
Vinorelbine
Indication: Breast Cancer Metastatic
Irinotecan Hydrochloride
Dosage: 100 mg/m2
Indication: Breast Cancer Metastatic
Docetaxel
Indication: Breast Cancer Metastatic
Paclitaxel
Indication: Breast Cancer Metastatic
Possible Vinorelbine side effects in female
Reported by a health professional (non-physician/pharmacist) from Italy on 2011-11-01
Patient: female
Reactions: Neutropenia, Hypertransaminasaemia
Drug(s) suspected as cause:
Vinorelbine
Dosage: 49 mg,(cyclic)
Indication: Breast Cancer
Start date: 2011-05-06
Zometa
Dosage: 4 mg, (cyclic)
Indication: Osteoporosis Prophylaxis
Start date: 2011-05-06
Other drugs received by patient: Telmisartan and Hydrochlorothiazide
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