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Vincristine (Vincristine) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (116)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Vincristine life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 116   Next >>

Possible Vincristine side effects in

Reported by a physician from United States on 2012-08-23

Patient:

Reactions: White Blood Cell Count Decreased, Neutrophil Count Decreased, Hypokalaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Cisplatin
    Dosage: 3.5 mg/kg/day over 6 hours on day 4
    Start date: 2012-07-27

Cisplatin
    Dosage: 3.5 mg/kg/day over 6 hours on day 4
    Indication: Medulloblastoma
    Start date: 2012-07-26
    End date: 2012-07-26

Cisplatin
    Dosage: 3.5 mg/kg/day over 6 hours on day 4
    Start date: 2012-07-02
    End date: 2012-07-02

Cyclophosphamide
    Dosage: 60 mg/kg/day over 1 hour on day 5 and 6
    Indication: Medulloblastoma
    Start date: 2012-07-27
    End date: 2012-07-28

Cyclophosphamide
    Dosage: 60 mg/kg/day over 1 hour on day 5 and 6
    Start date: 2012-07-03
    End date: 2012-07-04

Etoposide
    Dosage: 2.5 mg/kg/day on days 4,5 and 6
    Start date: 2012-07-02
    End date: 2012-07-04

Etoposide
    Dosage: 2.5 mg/kg/day on days 4,5 and 6
    Start date: 2012-07-29

Etoposide
    Dosage: 2.5 mg/kg/day on days 4,5 and 6
    Indication: Medulloblastoma
    Start date: 2012-07-26
    End date: 2012-07-28

Furosemide
    Dosage: 5 mg, qd
    Start date: 2012-07-28
    End date: 2012-07-29

Isotretinoin
    Dosage: 80 mg/m2/dose, bid on days 1-4
    Administration route: Oral
    Indication: Medulloblastoma
    Start date: 2012-07-23
    End date: 2012-07-27

Isotretinoin
    Dosage: 80 mg/m2/dose, bid on days 1-4
    Administration route: Oral
    Start date: 2012-06-29

Vincristine
    Dosage: 0.05 mg/kg/day on days 4 11 and 18
    Start date: 2012-07-02

Vincristine
    Dosage: 0.05 mg/kg/day on days 4 11 and 18
    Indication: Medulloblastoma
    Start date: 2012-07-23

Vincristine
    Dosage: 0.05 mg/kg/day on days 4 11 and 18
    Start date: 2012-07-27

Vorinostat
    Dosage: 230 mg/m2/dose on days 1-4
    Administration route: Oral
    Start date: 2012-06-29

Vorinostat
    Dosage: 230 mg/m2/dose on days 1-4
    Administration route: Oral
    Indication: Medulloblastoma
    Start date: 2012-07-23
    End date: 2012-07-25



Possible Vincristine side effects in

Reported by a physician from United States on 2012-08-20

Patient:

Reactions: Multi-Organ Failure, Sepsis, Hypoxia

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia

PEG-Asparaginase
    Indication: Acute Lymphocytic Leukaemia

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in female

Reported by a physician from United States on 2012-08-20

Patient: female, weighing 70.8 kg (155.8 pounds)

Reactions: Abdominal Pain, Hyperpyrexia, Anaphylactic Reaction, Chills, Pain, Hepatic Failure, Transaminases Increased, Splenic Infarction, Loss of Consciousness, Aortic Thrombosis, Off Label Use, Malaise, C-Reactive Protein Increased, Myositis, Dyspnoea, Hypotension, Arrhythmia, Lung Consolidation, Hypophosphataemia, Zygomycosis, Bacteraemia, Ventricular Tachycardia, Hyperammonaemia, Neutropenia, Hepatic Infarction, Shock, Infusion Related Reaction

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Cytarabine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Decadron Phosphate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Doxil
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Methotrexate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2005-01-01
    End date: 2007-01-01

PEG-Asparaginase
    Dosage: day 2, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-25
    End date: 2007-10-25

Velcade
    Dosage: day 1, 4, 8 and 11
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Vincristine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23



Possible Vincristine side effects in

Reported by a physician from United States on 2012-08-20

Patient:

Reactions: Multi-Organ Failure, Sepsis, Cerebral Ischaemia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia

PEG-Asparaginase
    Indication: Acute Lymphocytic Leukaemia

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in

Reported by a physician from United States on 2012-08-20

Patient:

Reactions: Multi-Organ Failure, Sepsis, Hypoxia, Pleural Effusion

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia

PEG-Asparaginase
    Indication: Acute Lymphocytic Leukaemia

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in 60 year old female

Reported by a physician from Czech Republic on 2012-08-17

Patient: 60 year old female

Reactions: Headache, Full Blood Count Decreased, Myopathy, Gastrointestinal Disorder, Platelet Count Decreased, Brain Oedema, Cerebral Hygroma, Intracranial Pressure Increased, Fluid Retention

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Asparaginase
    Dosage: unk
    Start date: 2012-06-25

Imatinib Mesylate
    Dosage: unk ukn, unk

Imatinib Mesylate
    Dosage: 600 mg, daily
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-06-11
    End date: 2012-06-28

Vincristine
    Dosage: unk
    Start date: 2012-06-25

Other drugs received by patient: Dexamethasone; Degan; Piperacillin and Tazobactam; Mykofungin; Zoloft; TPN; Neupogen; Cyclophosphamide; Torecan; Sulfamethoxazole and Trimethoprim; Omeprazole



Possible Vincristine side effects in 9 year old male

Reported by a physician from United States on 2012-08-17

Patient: 9 year old male

Reactions: Respiratory Failure, Disseminated Cryptococcosis, Septic Shock

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: daily
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia

Pegaspargase
    Dosage: single dose
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Dosage: weekly
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in female

Reported by a physician from France on 2012-08-14

Patient: female, weighing 65.0 kg (143.0 pounds)

Reactions: Pulmonary Oedema, Myocardial Infarction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Cyclophosphamide
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Istodax
    Dosage: 22 milligram
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Prednisone TAB
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Vincristine
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Other drugs received by patient: Gemox



Possible Vincristine side effects in female

Reported by a physician from United States on 2012-08-14

Patient: female, weighing 70.8 kg (155.8 pounds)

Reactions: Abdominal Pain, Rhabdomyolysis, Hyperpyrexia, Chills, Anaphylactic Reaction, Bone Pain, Hepatic Failure, Transaminases Increased, Loss of Consciousness, Aortic Thrombosis, Splenic Infarction, Hypokalaemia, Malaise, C-Reactive Protein Increased, Dyspnoea, Hypotension, Hypophosphataemia, Zygomycosis, Bacteraemia, Hyperammonaemia, Neutropenia, Hepatic Infarction, Lung Infiltration, Shock, Infusion Related Reaction

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: 70 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2005-01-01
    End date: 2007-10-23

Decadron Phosphate
    Dosage: 9 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Doxorubicin HCL
    Dosage: 107 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Methotrexate Sodium
    Dosage: unk, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2005-01-01
    End date: 2007-01-01

Pegaspargase
    Dosage: unk, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-25

Velcade
    Dosage: 1.3 mg/m2, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Vincristine
    Dosage: 2 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23



Possible Vincristine side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-13

Patient: female

Reactions: Septic Shock, Splenic Infarction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Nodal Marginal Zone B-Cell Lymphoma
    Start date: 2012-06-29
    End date: 2012-06-29

Prednisone TAB
    Dosage: 1 tablet
    Administration route: Oral
    Indication: Nodal Marginal Zone B-Cell Lymphoma
    Start date: 2012-06-28

Vincristine
    Dosage: 1 unit
    Indication: Nodal Marginal Zone B-Cell Lymphoma
    Start date: 2012-06-29
    End date: 2012-06-29

Other drugs received by patient: Aspirin; Acetaminophen; Fasturtec; Pravastatine Arrow; Venlafaxine; Potassium Chloride; Ramipril; Nexium; Bisoprolol Fumarate



Possible Vincristine side effects in

Reported by a physician from United Kingdom on 2012-08-09

Patient:

Reactions: Small Intestinal Obstruction, Vomiting, Nausea, Abdominal Pain Upper

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1340 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Doxorubicin Hydrochloride
    Dosage: 90 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Prednisolone
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Rituximab
    Dosage: 670 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Velcade
    Dosage: 2.3 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-30
    End date: 2012-06-08

Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Other drugs received by patient: Acyclovir; Allopurinol; Amitriptyline HCL; Omeprazole; Amitriptyline HCL; Metoclopramide; Metoclopramide



Possible Vincristine side effects in female

Reported by a physician from United Kingdom on 2012-08-08

Patient: female, weighing 43.0 kg (94.6 pounds)

Reactions: Meningitis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-08
    End date: 2012-06-13

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-08
    End date: 2012-06-13

Prednisone TAB
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-07
    End date: 2012-06-13

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-08
    End date: 2012-06-13



Possible Vincristine side effects in 74 year old male

Reported by a consumer/non-health professional from United States on 2012-08-03

Patient: 74 year old male

Reactions: Blood Bilirubin Increased, Pneumonia, Atrial Fibrillation, Hepatic Enzyme Increased, Death, Enterococcal Sepsis, Fluid Retention, Cardiac Failure Congestive

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Daunorubicin HCL
    Dosage: on days 1,8,15,22
    Indication: Acute Lymphocytic Leukaemia

Elspar

Methotrexate
    Dosage: day15
    Indication: Acute Lymphocytic Leukaemia

Prednisone
    Indication: Acute Lymphocytic Leukaemia

Sprycel
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-22

Vincristine
    Dosage: on days 1,8,15,22
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-01

Patient: female

Reactions: Acute Myeloid Leukaemia, Myelodysplastic Syndrome

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Alkeran
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Bicnu
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Cyclophosphamide
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Dexamethasone
    Start date: 2008-04-08

Dexamethasone
    Start date: 2008-06-01
    End date: 2008-01-01

Dexamethasone
    Indication: Multiple Myeloma
    Start date: 2008-05-05

Dexamethasone
    Start date: 2008-05-19

Doxorubicin Hydrochloride
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Prednisone
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Velcade
    Indication: Multiple Myeloma
    Start date: 2008-04-08
    End date: 2008-09-01

Vepesid
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Vincristine
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01



Possible Vincristine side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-01

Patient: female

Reactions: Acute Myeloid Leukaemia, Myelodysplastic Syndrome

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Alkeran
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Bicnu
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Cyclophosphamide
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Dexamethasone
    Indication: Multiple Myeloma
    Start date: 2004-01-01
    End date: 2008-01-01

Dexamethasone
    Start date: 2008-04-08
    End date: 2008-09-01

Doxorubicin Hydrochloride
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Prednisone
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Velcade
    Indication: Multiple Myeloma
    Start date: 2008-04-08
    End date: 2008-06-01

Vepesid
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01

Vincristine
    Indication: Multiple Myeloma
    Start date: 2000-01-01
    End date: 2000-01-01



Possible Vincristine side effects in female

Reported by a physician from France on 2012-07-31

Patient: female, weighing 65.0 kg (143.0 pounds)

Reactions: Pulmonary Oedema, Myocardial Infarction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Cyclophosphamide
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Istodax
    Dosage: 22 milligram
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Prednisone TAB
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Vincristine
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2012-06-06
    End date: 2012-06-06

Other drugs received by patient: Gemox



Possible Vincristine side effects in

Reported by a physician from United Kingdom on 2012-07-30

Patient:

Reactions: Small Intestinal Obstruction, Vomiting, Nausea, Abdominal Pain Upper

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1340 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Doxorubicin Hydrochloride
    Dosage: 90 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Prednisolone
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Rituximab
    Dosage: 670 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Velcade
    Dosage: 2.3 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-30
    End date: 2012-06-08

Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Other drugs received by patient: Omeprazole; Metoclopramide; Amitriptyline Hydrochloride; Allopurinol; Amitriptyline Hydrochloride; Metoclopramide; Acyclovir



Possible Vincristine side effects in

Reported by a physician from Korea, Republic of on 2012-07-30

Patient:

Reactions: Blood Bilirubin Increased, Hepatic Function Abnormal, Transaminases Increased, Disease Progression

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 750 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Doxil
    Dosage: 50 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Prednisone
    Dosage: 100 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-26

Velcade
    Dosage: 1.60 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Vincristine
    Dosage: 1.4 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22



Possible Vincristine side effects in 79 year old female

Reported by a consumer/non-health professional from United Kingdom on 2012-07-30

Patient: 79 year old female

Reactions: Cardiac Arrest

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-18
    End date: 2012-06-18

Etoposide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-18
    End date: 2012-06-18

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-18
    End date: 2012-06-18

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-18
    End date: 2012-06-18

Other drugs received by patient: Prednisolone



Possible Vincristine side effects in female

Reported by a consumer/non-health professional from United Kingdom on 2012-07-27

Patient: female, weighing 43.0 kg (94.6 pounds)

Reactions: Meningitis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-08
    End date: 2012-06-13

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-08
    End date: 2012-06-13

Prednisone
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-07
    End date: 2012-06-13

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-03-08
    End date: 2012-06-13



Possible Vincristine side effects in female

Reported by a physician from United Kingdom on 2012-07-27

Patient: female, weighing 53.0 kg (116.6 pounds)

Reactions: Anaemia, Neutropenia, Hypokalaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-23

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-23

Furosemide

Prednisone
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-23

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-23



Possible Vincristine side effects in

Reported by a physician from Korea, Republic of on 2012-07-24

Patient:

Reactions: Blood Bilirubin Increased, Hepatic Function Abnormal, Transaminases Increased, Disease Progression

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 750 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Doxil
    Dosage: 50 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Prednisone
    Dosage: 100 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-26

Velcade
    Dosage: 1.60 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Vincristine
    Dosage: 1.4 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22



Possible Vincristine side effects in 17 year old male

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-07-23

Patient: 17 year old male

Reactions: Abdominal Pain, Rhabdomyolysis, Pain in Extremity, Disseminated Intravascular Coagulation, Chromaturia, Pancytopenia, Pyrexia, Renal Failure, Renal Impairment, Diarrhoea, Clostridial Infection, Septic Shock

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cefepime
    Indication: Pyrexia

Doxorubicin HCL
    Indication: Ewing's Sarcoma Metastatic

Etoposide
    Indication: Ewing's Sarcoma Metastatic

Ifosfamide
    Indication: Ewing's Sarcoma Metastatic

Netilmicin Sulfate
    Indication: Pyrexia

Vincristine
    Indication: Ewing's Sarcoma Metastatic



Possible Vincristine side effects in female

Reported by a consumer/non-health professional from United Kingdom on 2012-07-23

Patient: female, weighing 67.0 kg (147.4 pounds)

Reactions: Small Intestinal Obstruction, Anaemia, Febrile Neutropenia, Device Related Infection

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Start date: 2012-04-26

Doxorubicin HCL
    Start date: 2012-04-26

Prednisolone
    Administration route: Oral
    Start date: 2012-04-26

Vincristine
    Start date: 2012-04-26



Possible Vincristine side effects in

Reported by a physician from Korea, Republic of on 2012-07-18

Patient:

Reactions: Blood Bilirubin Increased, Hepatic Function Abnormal, Transaminases Increased, Disease Progression

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 750.00 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Doxorubicin HCL
    Dosage: 50.00 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Prednisone
    Dosage: 100.00 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-26

Velcade
    Dosage: 1.60 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22

Vincristine
    Dosage: 1.40 mg/m2, unk
    Indication: T-Cell Lymphoma
    Start date: 2008-01-24
    End date: 2008-02-22



Possible Vincristine side effects in

Reported by a physician from United Kingdom on 2012-07-18

Patient:

Reactions: Neutropenic Sepsis, Respiratory Arrest

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1300 mg, unk
    Start date: 2010-11-05

Cyclophosphamide
    Dosage: 1300 mg, unk
    Indication: Mantle Cell Lymphoma
    Start date: 2010-08-24
    End date: 2010-11-05

Doxorubicin HCL
    Dosage: 90 mg, unk
    Indication: Mantle Cell Lymphoma
    Start date: 2010-08-24

Doxorubicin HCL
    Dosage: 83 unk, unk
    Start date: 2010-11-05

Prednisone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: Mantle Cell Lymphoma
    Start date: 2010-08-24
    End date: 2010-11-05

Prednisone
    Dosage: 100 mg, unk
    Administration route: Oral
    Start date: 2010-11-05

Velcade
    Dosage: 2.8 mg, unk
    Indication: Mantle Cell Lymphoma
    Start date: 2010-08-24

Velcade
    Dosage: 1.3 unk, unk
    Start date: 2010-11-05
    End date: 2010-11-12

Vincristine
    Dosage: 2 mg, unk
    Indication: Mantle Cell Lymphoma
    Start date: 2010-08-24

Other drugs received by patient: Metoclopramide; Simvastatin; Ramipril; Acyclovir; Piperacillin and Tazobactam; Fluoxetine HCL; E45; Aspirin; Gaviscon; Bisoprolol Fumarate; Omeprazole



Possible Vincristine side effects in 54 year old female

Reported by a physician from France on 2012-07-13

Patient: 54 year old female

Reactions: Leukaemia, Leukaemia Plasmacytic

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: cumulative total dose of doxorubicine of 504 mg (300 mg/m2)
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16

Etoposide
    Dosage: (500 mg)
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-01-01
    End date: 2011-01-01

Ifosfamide
    Dosage: 2480 mg
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-01-01
    End date: 2011-01-01

Mabthera
    Dosage: 650 mg
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16

Methotrexate
    Dosage: (4500 mg)
    Start date: 2012-05-14

Methotrexate
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-09-13
    End date: 2010-09-28

Methylprednisolone
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16

Prednisone
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16

Vincristine
    Indication: non-Hodgkin's Lymphoma
    Start date: 2010-05-10
    End date: 2010-08-16



Possible Vincristine side effects in female

Reported by a physician from United Kingdom on 2012-07-09

Patient: female, weighing 51.5 kg (113.3 pounds)

Reactions: Mucosal Inflammation, Acute Respiratory Distress Syndrome, Febrile Bone Marrow Aplasia, Encephalopathy

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Dactinomycin
    Dosage: 2 mg
    Indication: Sarcoma Metastatic
    Start date: 2010-07-16

Doxorubicin HCL
    Dosage: 92 mg
    Indication: Sarcoma Metastatic
    Start date: 2010-07-16

Doxorubicin HCL
    Dosage: 30 mg/m2

Ifosfamide
    Dosage: 6 g/m2
    Indication: Sarcoma Metastatic
    Start date: 2010-07-16

Ifosfamide
    Dosage: 6 g,2
    Start date: 2010-09-12

Vincristine
    Dosage: 2 mg
    Indication: Sarcoma Metastatic
    Start date: 2010-07-16

Other drugs received by patient: Mutesa / 00858001 /; Lasix; Acetaminophen; Nicardipine HCL; Sufentanil Citrate; Xanax; Acetaminophen; Plitican; Emend; Omeprazole; Tramadol HCL; Albumin (Human); Bactrim



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-06-27

Patient:

Reactions: Angina Pectoris, Death, Ejection Fraction Decreased, Cardiotoxicity, Cardiovascular Disorder, Lymphoma, Myocardial Infarction, Infection

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Lymphoma

Doxorubicin HCL
    Dosage: average dose: 336,5 mg/m2 (range 50-680)
    Indication: Lymphoma

Prednisolone
    Indication: Lymphoma

Vincristine
    Indication: Lymphoma



Possible Vincristine side effects in male

Reported by a physician from Netherlands on 2012-06-21

Patient: male, weighing 82.0 kg (180.4 pounds)

Reactions: Neoplasm Progression, Pulmonary Embolism, Fall, Diffuse Large B-Cell Lymphoma

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: last dose prior to the sae on 28/apr/2012
    Indication: Malignant Lymphoid Neoplasm
    Start date: 2012-04-25

Doxorubicin HCL
    Dosage: last dose prior to the sae on 28/apr/2012
    Indication: Malignant Lymphoid Neoplasm
    Start date: 2012-04-25

Filgrastim
    Dosage: last dose prior to the sae on 26/apr/2012
    Indication: Malignant Lymphoid Neoplasm
    Start date: 2012-04-26

Mabthera
    Dosage: last dose prior to the sae on 29/apr/2012
    Indication: Malignant Lymphoid Neoplasm
    Start date: 2012-04-25

Prednisone
    Dosage: last dose prior to the sae on 28/apr/2012
    Administration route: Oral
    Indication: Malignant Lymphoid Neoplasm
    Start date: 2012-04-25

Vincristine
    Dosage: last dose prior to the sae on 28/apr/2012
    Indication: Malignant Lymphoid Neoplasm
    Start date: 2012-04-25

Other drugs received by patient: Omeprazole; Hydrochlorothiazide; Enalapril Maleate



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