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Vincristine (Vincristine) - Hospitalization - Suspected Cause - Side Effect Reports

 
 



Index of reports > Hospitalization (1020)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Vincristine hospitalization. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 1020   Next >>

Possible Vincristine side effects in 10 year old male

Reported by a physician from United States on 2012-08-27

Patient: 10 year old male, weighing 76.1 kg (167.4 pounds)

Reactions: Hypersensitivity, Hyperglycaemia, Peripheral Motor Neuropathy

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1000mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Cytarabine
    Dosage: 75mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Mercaptopurine
    Dosage: 60mgm2 cyclic
    Administration route: Oral
    Indication: T-Cell Type Acute Leukaemia

Methotrexate
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-06-06

Nelarabine
    Dosage: 650mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-05-22

PEG-Asparaginase
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-06-13

Vincristine
    Dosage: 1.5mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-06-13

Other drugs received by patient: Radiation



Possible Vincristine side effects in female

Reported by a physician from Switzerland on 2012-08-27

Patient: female, weighing 87.7 kg (192.9 pounds)

Reactions: Cholecystitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-11

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-11

Prednisolone
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-12

Rituximab
    Dosage: concentration 1/mg/ml
    Start date: 2011-11-11

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-11

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-11-11

Other drugs received by patient: Pantoprazole; Exforge HCT; Dipyrone INJ; Bisoprolol Fumarate; Domperidon; Bactrim DS; Acetaminophen; Metformin Hydrochloride



Possible Vincristine side effects in male

Reported by a physician from Netherlands on 2012-08-27

Patient: male, weighing 95.0 kg (209.0 pounds)

Reactions: Cranial Nerve Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: third maintenance cycle
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2010-09-06

Cyclophosphamide

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: third maintenance cycle
    Start date: 2010-09-06

Neupogen
    Indication: Diffuse Large B-Cell Lymphoma

Neupogen
    Dosage: third maintenance cycle
    Start date: 2010-09-07

Prednisone TAB
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Dosage: third maintenance cycle
    Administration route: Oral
    Start date: 2010-09-06

Rituximab
    Dosage: third maintenance cycle
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2010-09-06

Rituximab
    Start date: 2010-11-29
    End date: 2011-03-21

Vincristine
    Dosage: third maintenance cycle
    Start date: 2010-09-06

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in male

Reported by a physician from France on 2012-08-27

Patient: male

Reactions: Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-21
    End date: 2012-05-23

Doxorubicin Hydrochloride
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-21
    End date: 2012-05-21

Levoleucovorin Calcium
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-21
    End date: 2012-05-25

Mabthera
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-19
    End date: 2012-05-19

Methotrexate Disodium
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-20

Methotrexate Disodium
    Start date: 2012-05-25

Prednisone TAB
    Administration route: Oral
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-20
    End date: 2012-05-24

Vincristine
    Start date: 2012-05-25

Vincristine
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-20

Other drugs received by patient: Cytarabine; Calciparine; Ondansetron Hydrochloride; Allopurinol; Valaciclovir HCL; Nexium; Lyrica; Bactrim DS; Emend



Possible Vincristine side effects in 47 year old male

Reported by a physician from France on 2012-08-27

Patient: 47 year old male

Reactions: Respiratory Tract Infection Bacterial, Epstein-Barr Virus Associated Lymphoma, Congestive Cardiomyopathy, Systolic Dysfunction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Start date: 2012-06-08

Doxorubicin HCL
    Start date: 2012-06-11
    End date: 2012-07-10

Mabthera
    Start date: 2012-06-11

Nexium
    Administration route: Oral

Prednisolone
    Administration route: Oral
    Start date: 2012-06-08

Vincristine
    Start date: 2012-06-08

Other drugs received by patient: Previscan; Methotrexate Sodium; Potassium Chloride; Kineret; Kineret; Kineret; Cacit D3; Aspirin; Prednisone TAB; Acetaminophen; Acetaminophen W / Codeine; Alendronate Sodium / Cholecalciferol



Possible Vincristine side effects in 79 year old female

Reported by a physician from Germany on 2012-08-27

Patient: 79 year old female

Reactions: Sciatica, Lumbar Vertebral Fracture

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Doxorubicin Hydrochloride
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Mabthera
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Prednisone
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Vincristine
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive



Possible Vincristine side effects in male

Reported by a physician from Germany on 2012-08-24

Patient: male

Reactions: Febrile Neutropenia, Skin Infection, Neutropenia, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1500 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Doxorubicin Hydrochloride
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Neulasta
    Dosage: 6 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-06
    End date: 2012-04-20

Prednisolone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-21

Rituximab
    Dosage: 750 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-01
    End date: 2012-04-16

Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Other drugs received by patient: MST / 00036302 /; Novalgin / 00169801 /; Rulid; Pantoprazole; Paspertin / 00041902 /; Acyclovir; Electrolytes NOS W / Macrogol 3350; Dipyrone INJ; Metoclopramide; Acyclovir



Possible Vincristine side effects in female

Reported by a physician from Thailand on 2012-08-24

Patient: female, weighing 57.4 kg (126.3 pounds)

Reactions: Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Doxorubicin Hydrochloride
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Mabthera
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Prednisone TAB
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Vincristine
    Indication: B-Cell Lymphoma
    Start date: 2012-03-02

Other drugs received by patient: Dexamethasone; Acetaminophen; Ondansetron; Metformin HCL; Ondansetron; Ondansetron; Atenolol; Simvastatin; Benadryl



Possible Vincristine side effects in 52 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24

Patient: 52 year old female

Reactions: Tumour Lysis Syndrome, Posterior Reversible Encephalopathy Syndrome, Insomnia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: according to larson regimen
    Indication: B Precursor Type Acute Leukaemia

Daunorubicin HCL
    Dosage: according to larson regimen
    Indication: B Precursor Type Acute Leukaemia

Daunorubicin HCL
    Dosage: at 50% dosage

Dexamethasone
    Indication: Premedication

Methylprednisolone Sodium Succinate
    Indication: B Precursor Type Acute Leukaemia

Prednisone TAB
    Dosage: according to larson regimen
    Indication: B Precursor Type Acute Leukaemia

Vincristine
    Dosage: according to larson regimen
    Indication: B Precursor Type Acute Leukaemia

Other drugs received by patient: Ondansetron; Voriconazole; Morphine Sulfate; Morphine



Possible Vincristine side effects in 18 year old female

Reported by a physician from Slovenia on 2012-08-23

Patient: 18 year old female

Reactions: Pulmonary Haemorrhage, Gastrointestinal Haemorrhage, Injection Site Haemorrhage, Sepsis, Shock Haemorrhagic, Acute Respiratory Distress Syndrome, Bone Marrow Failure, Staphylococcal Bacteraemia, Septic Shock

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Heparin

Vincristine
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in male

Reported by a physician from Germany on 2012-08-23

Patient: male, weighing 85.0 kg (187.0 pounds)

Reactions: Ascites

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Chemotherapy

Diuretics

Mabthera
    Dosage: unk
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-07-28
    End date: 2012-07-28

Prednisone TAB
    Indication: Chemotherapy

Ramipril

Vincristine
    Indication: Chemotherapy

Other drugs received by patient: Torsemide; Allopurinol; Allopurinol; Pantoprazole; Pantoprazole; Potassium Chloride; Metoprolol Tartrate; Potassium Chloride; Ramipril; Hydrochlorothiazide



Possible Vincristine side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-23

Patient: male

Reactions: Congestive Cardiomyopathy, Systolic Dysfunction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Start date: 2012-06-26
    End date: 2012-06-26

Cyclophosphamide
    Start date: 2012-07-10
    End date: 2012-07-10

Cyclophosphamide
    Start date: 2012-06-08
    End date: 2012-06-08

Cyclophosphamide
    Start date: 2012-06-11
    End date: 2012-06-11

Doxorubicine Actavis
    Start date: 2012-06-26
    End date: 2012-06-29

Doxorubicine Actavis
    Start date: 2012-06-11
    End date: 2012-06-11

Doxorubicine Actavis
    Start date: 2012-07-10
    End date: 2012-07-10

Mabthera
    Start date: 2012-06-11
    End date: 2012-06-11

Mabthera
    Start date: 2012-06-26
    End date: 2012-06-26

Mabthera
    Start date: 2012-06-28
    End date: 2012-06-28

Mabthera
    Start date: 2012-07-05
    End date: 2012-07-05

Mabthera
    Start date: 2012-07-10
    End date: 2012-07-10

Nexium
    Administration route: Oral

Prednisolone
    Administration route: Oral
    Start date: 2012-06-08

Vincristine
    Start date: 2012-06-08
    End date: 2012-06-08

Vincristine
    Start date: 2012-06-11
    End date: 2012-06-11

Vincristine
    Start date: 2012-06-26
    End date: 2012-06-26

Vincristine
    Start date: 2012-07-10
    End date: 2012-07-10

Other drugs received by patient: Etoposide; Cacit D3; Aspirin; Acetaminophen; Prednisone TAB; Acetaminophen W / Codeine; Alendronate Sodium / Cholecalciferol; Previscan; Methotrexate Sodium; Potassium Chloride



Possible Vincristine side effects in 17 year old male

Reported by a physician from Poland on 2012-08-23

Patient: 17 year old male

Reactions: Rhabdomyolysis, Disseminated Intravascular Coagulation, Pancytopenia, Pyrexia, Renal Failure, Neutropenia, Clostridial Infection, Septic Shock

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cefepime

Doxorubicin Hydrochloride
    Indication: Ewing's Sarcoma

Etoposide
    Indication: Ewing's Sarcoma Metastatic

Ifosfamide
    Indication: Ewing's Sarcoma Metastatic

Meropenem

Metronidazole

Netromycin

Vancocin Hydrochloride

Vincristine
    Indication: Ewing's Sarcoma Metastatic

Other drugs received by patient: Fluconazole; Caspofungin Acetate



Possible Vincristine side effects in female

Reported by a pharmacist from United States on 2012-08-23

Patient: female, weighing 9.1 kg (20.0 pounds)

Reactions: Extravasation, Crying, Infusion Site Oedema

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine

Other drugs received by patient: Lactulose; Zofran; Lidocain / Prilocaine; Miralax; Maxitrol



Possible Vincristine side effects in

Reported by a physician from United Kingdom on 2012-08-22

Patient:

Reactions: Cystitis Noninfective

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1222.5 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-24
    End date: 2012-08-02

Doxorubicin HCL
    Dosage: 81.5 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-24
    End date: 2012-08-02

Prednisolone
    Dosage: 100 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-24
    End date: 2012-08-02

Rituximab
    Dosage: 611.75 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-24
    End date: 2012-08-02

Velcade
    Dosage: 2.11 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-12
    End date: 2012-08-09

Vincristine
    Dosage: 2 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-24
    End date: 2012-08-02



Possible Vincristine side effects in male

Reported by a physician from United States on 2012-08-22

Patient: male, weighing 55.2 kg (121.4 pounds)

Reactions: Unresponsive To Stimuli, Moaning, Neutropenia, Septic Shock, Cardiac Arrest

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Start date: 2009-08-21

Methotrexate Sodium

Prednisone

Vincristine
    End date: 2012-08-10



Possible Vincristine side effects in male

Reported by a physician from France on 2012-08-22

Patient: male

Reactions: Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-21
    End date: 2012-05-23

Doxorubicin Hydrochloride
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-21
    End date: 2012-05-21

Levoleucovorin Calcium
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-21
    End date: 2012-05-26

Mabthera
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-19
    End date: 2012-05-19

Methotrexate Disodium
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-20
    End date: 2012-05-20

Prednisone TAB
    Administration route: Oral
    Indication: Burkitt's Lymphoma
    Start date: 2012-05-20
    End date: 2012-05-25

Vincristine
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-20
    End date: 2012-05-26

Other drugs received by patient: Valaciclovir HCL; Lyrica; Bactrim DS; Emend; Allopurinol; Cytarabine; Ondansetron Hydrochloride; Nexium; Calciparine



Possible Vincristine side effects in male

Reported by a physician from United States on 2012-08-22

Patient: male

Reactions: Rectal Haemorrhage, Constipation, Cardiac Disorder, Hospitalisation, Granulocytopenia, Inappropriate Antidiuretic Hormone Secretion, Thrombocytopenia, Cardiac Failure Congestive, Pneumonia, Anaemia, Pancytopenia, Atrial Fibrillation, Febrile Neutropenia, Syncope, Embolism, Sepsis, Dehydration, Asthenia, Mantle Cell Lymphoma Recurrent, Leukopenia, Deep Vein Thrombosis, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Cyclophosphamide
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Mantle Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Mantle Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Mantle Cell Lymphoma



Possible Vincristine side effects in

Reported by a physician from United States on 2012-08-22

Patient:

Reactions: Abdominal Pain, Thrombosis, Hyperkalaemia, Coagulopathy, Hypoglycaemia, Hypocalcaemia, Hypoxia, Hiccups, Alanine Aminotransferase Abnormal, Pneumonitis, Cough, Pain in Extremity, Hypotension, Hyperglycaemia, External Ear Pain, Haematotoxicity, Dehydration, Lower Gastrointestinal Haemorrhage, Hypofibrinogenaemia, Aspartate Aminotransferase Abnormal, Hypokalaemia, Blood Bilirubin Abnormal, Pleural Effusion, Decreased Appetite, Gamma-Glutamyltransferase Abnormal, Hyponatraemia, Hypercalcaemia, Hypophosphataemia, Diarrhoea, Hypoalbuminaemia, Hypertension, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Asparaginase
    Dosage: 2500 units/m2/dose as 4 weekly doses
    Indication: Acute Lymphocytic Leukaemia

Bortezomib
    Dosage: 1.3 mg/sq.m/dose on days 1, 4, 8 and 11 combined with vxld
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Dosage: on day 1 for all patients and on days 8, 15, 22 for cns invlovment
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone
    Dosage: 10 mg/m2/day divided in to 2 doses for 14 consecutive days
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin HCL
    Dosage: given over 15-30 minutes on day 1
    Indication: Acute Lymphocytic Leukaemia

Hydrocortisone
    Dosage: on days 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Methotrexate Sodium
    Dosage: 1 dose on day 15 for no cns involvement and on days 8, 15, 22 for cns involvement
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Dosage: 1.5 mg/m2/dose, max. 2 mg, by push on days 1, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Other drugs received by patient: Vancomycin; Posaconazole; Voriconazole; Levofloxacin



Possible Vincristine side effects in 8 year old female

Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-08-21

Patient: 8 year old female

Reactions: Mucoepidermoid Carcinoma

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin HCL
    Indication: Acute Lymphocytic Leukaemia

Elspar
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Mercaptopurine
    Indication: Acute Lymphocytic Leukaemia

Methotrexate

Methotrexate
    Indication: Acute Lymphocytic Leukaemia

Prednisone TAB
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male, weighing 115.7 kg (254.5 pounds)

Reactions: Gastrointestinal Haemorrhage, Cholecystitis Acute, T-Cell Lymphoma, Disseminated Intravascular Coagulation, Pancytopenia, Atrial Fibrillation, Multi-Organ Failure, Sepsis, Acute Respiratory Distress Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: T-Cell Lymphoma
    Start date: 2006-09-10

Cyclophosphamide
    Indication: T-Cell Lymphoma
    Start date: 2006-01-01

Prednisone TAB
    Indication: T-Cell Lymphoma
    Start date: 2006-01-01

Remicade
    Dosage: 3 dose induction followed by maint. q 8 weeks, 300 mg on 29-jun-2006, total 27 infusions
    Indication: Rheumatoid Arthritis
    Start date: 2001-10-01
    End date: 2006-06-29

Vincristine
    Indication: T-Cell Lymphoma
    Start date: 2006-09-10

Other drugs received by patient: Azulfadine; Lisinopril



Possible Vincristine side effects in female

Reported by a physician from Denmark on 2012-08-21

Patient: female, weighing 74.0 kg (162.8 pounds)

Reactions: Back Pain, Pulmonary Embolism

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Cyclophosphamide
    Dosage: 05/mar/2012: last dose prioe to onset of sae
    Start date: 2012-03-05

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Doxorubicin HCL
    Start date: 2012-03-05

Mabthera
    Dosage: last dose prior to sae was on 13/feb/2012
    Start date: 2012-03-05

Mabthera
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Mabthera
    Start date: 2012-02-13

Neulasta
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-10
    End date: 2012-02-10

Neulasta
    Start date: 2012-02-23

Neulasta
    Start date: 2012-03-08

Prednisone TAB
    Dosage: last dose prior to sae was on 9/mar/2012
    Administration route: Oral
    Start date: 2012-03-05

Prednisone TAB
    Administration route: Oral
    Start date: 2012-02-27
    End date: 2012-02-27

Prednisone TAB
    Administration route: Oral
    Start date: 2012-02-20
    End date: 2012-02-24

Prednisone TAB
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Vincristine
    Start date: 2012-03-05

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Other drugs received by patient: Acyclovir; Ondansetron; Tramadol HCL; Lansoprazole; Acyclovir; Lansoprazole; Bactrim



Possible Vincristine side effects in 41 year old male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-21

Patient: 41 year old male

Reactions: Ecthyma, Pseudomonas Infection, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: B-Cell Lymphoma

Doxorubicin HCL
    Indication: B-Cell Lymphoma

Prednisone TAB
    Dosage: unk
    Indication: B-Cell Lymphoma

Rituximab
    Indication: B-Cell Lymphoma

Vincristine
    Indication: B-Cell Lymphoma



Possible Vincristine side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male, weighing 13.6 kg (29.9 pounds)

Reactions: Contusion, Vomiting, Flatulence, Hypotension, Tachycardia, Gastrointestinal Necrosis, Cardio-Respiratory Arrest, Hypophagia, Abdominal Distension, Bacterial Test Positive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: it 2-2.99 yrs 50 mg

Dexamethasone TAB
    Dosage: po 3 mg/m2 dose (1.75 bid)
    Administration route: Oral

Methotrexate Sodium
    Dosage: it 2 mg/m2

PEG-L Asparaginase (Pegaspaegase, Oncospar)
    Dosage: iv 2500 units/m2

Vincristine
    Dosage: iv 1.5mg/m2 on day 1 and day 8



Possible Vincristine side effects in male

Reported by a consumer/non-health professional from Germany on 2012-08-21

Patient: male, weighing 86.0 kg (189.2 pounds)

Reactions: Pneumonia, Pulmonary Embolism, Cytomegalovirus Infection, Pulmonary Infarction, Lymphoma, Staphylococcal Sepsis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1500 mg, qd (day 1)
    Indication: T-Cell Lymphoma
    Start date: 2009-12-07
    End date: 2010-01-11

Doxorubicin HCL
    Dosage: 100 mg, qd (day 1)
    Indication: T-Cell Lymphoma
    Start date: 2009-12-07
    End date: 2010-01-11

Filgrastim
    Dosage: 48 unk, qd (day 1)
    Indication: T-Cell Lymphoma
    Start date: 2009-12-25
    End date: 2010-01-15

Mabcampath
    Dosage: 30 mg, day 4 and 5 of each cycle 1-3
    Indication: T-Cell Lymphoma
    Start date: 2009-12-10
    End date: 2010-01-15

Prednisone
    Dosage: 10 mg, qd (day 1-5)
    Administration route: Oral
    Indication: T-Cell Lymphoma
    Start date: 2009-11-27
    End date: 2010-01-10

Vincristine
    Dosage: 1 mg, qd (day 1)
    Indication: T-Cell Lymphoma
    Start date: 2009-11-26
    End date: 2010-01-11

Other drugs received by patient: Torsemide; Metoprolol Succinate; Heparin; Marcumar; Pantoprazole; Sulfamethoprim



Possible Vincristine side effects in 45 year old female

Reported by a physician from United States on 2012-08-21

Patient: 45 year old female

Reactions: Epstein-Barr Virus Infection, Splenic Infection Fungal, Mycosis Fungoides Refractory, Granuloma, Pneumonia Cytomegaloviral

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Campath
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-06-01

Cisplatin
    Dosage: unk
    Indication: Mycosis Fungoides

Cyclophosphamide
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-01-01

Daunorubicin HCL
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-01-01

Dexamethasone
    Dosage: unk
    Indication: Mycosis Fungoides

Etoposide
    Dosage: unk
    Indication: Mycosis Fungoides

Fludara
    Dosage: 2 cycles
    Indication: Mycosis Fungoides

Ifosfamide
    Dosage: unk
    Indication: Mycosis Fungoides

Prednisone
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-01-01

Vincristine
    Dosage: unk
    Indication: Mycosis Fungoides
    Start date: 2006-01-01



Possible Vincristine side effects in 3 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-20

Patient: 3 year old male

Reactions: Histiocytosis Haematophagic

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: 18 mg/m2, cyclic (18 mg/m 2 for 5 days on days 1 to 5)

Cyclophosphamide
    Dosage: 1200 mg/m2, cyclic (1200 mg/m2 for 1 day on day 1)

Doxorubicin HCL
    Dosage: 25 mg/m2, cyclic (25 mg/m2 for 1 day on day 3)

Vincristine
    Dosage: 1.5 mg/m2, cyclic (1.5 mg/m2 for 1 day on day 1)

Other drugs received by patient: Allopurinol; Dalteparin Sodium



Possible Vincristine side effects in male

Reported by a physician from United Kingdom on 2012-08-20

Patient: male

Reactions: Neutropenic Sepsis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1700mg per day
    Indication: Richter's Syndrome
    Start date: 2012-07-27
    End date: 2012-07-27

Doxorubicin Hydrochloride
    Dosage: 120mg per day
    Indication: Richter's Syndrome
    Start date: 2012-07-27
    End date: 2012-07-27

Ofatumumab
    Indication: Richter's Syndrome
    Start date: 2012-07-30

Prednisolone
    Dosage: 95mg per day
    Administration route: Oral
    Indication: Richter's Syndrome
    Start date: 2012-07-27
    End date: 2012-07-31

Vincristine
    Dosage: 2mg per day
    Indication: Richter's Syndrome
    Start date: 2012-07-27
    End date: 2012-07-27

Other drugs received by patient: Voriconazole; Ranitidine; Prednisolone; Sertraline Hydrochloride; Acyclovir



Possible Vincristine side effects in

Reported by a physician from United States on 2012-08-20

Patient:

Reactions: Multi-Organ Failure, Sepsis, Cerebral Ischaemia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia

PEG-Asparaginase
    Indication: Acute Lymphocytic Leukaemia

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in

Reported by a physician from United States on 2012-08-20

Patient:

Reactions: Abdominal Pain, Thrombosis, Hyperkalaemia, Hypoglycaemia, Coagulopathy, Hypokalaemia, Blood Bilirubin Abnormal, Hiccups, Pleural Effusion, Hypoxia, Hypocalcaemia, Alanine Aminotransferase Abnormal, Cough, Pneumonitis, Decreased Appetite, Pain in Extremity, Hypotension, Hyperglycaemia, Gamma-Glutamyltransferase Abnormal, Hyponatraemia, External Ear Pain, Hypercalcaemia, Haematotoxicity, Hypophosphataemia, Diarrhoea, Dehydration, Hypoalbuminaemia, Lower Gastrointestinal Haemorrhage, Hypertension, Hypofibrinogenaemia, Aspartate Aminotransferase Abnormal, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Asparaginase
    Dosage: 2500 units/m2/dose as 4 weekly doses
    Indication: Acute Lymphocytic Leukaemia

Bortezomib
    Dosage: 1.3 mg/sq.m/dose on days 1, 4, 8 and 11 combined with vxld
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Dosage: on day 1 for all patients and on days 8, 15, 22 for cns invlovment
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone
    Dosage: 10 mg/m2/day divided in to 2 doses for 14 consecutive days
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Dosage: given over 15-30 minutes on day 1
    Indication: Acute Lymphocytic Leukaemia

Hydrocortisone
    Dosage: on days 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: 1 dose on day 15 for no cns involvement and on days 8, 15, 22 for cns involvement
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Dosage: 1.5 mg/m2/dose, max. 2 mg, by push on days 1, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Other drugs received by patient: Levofloxacin; Voriconazole; Posaconazole; Vancomycin



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