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Vincristine (Vincristine) - Toxicity To Various Agents - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Toxicity To Various Agents (89)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Vincristine where reactions include toxicity to various agents. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 89   Next >>

Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Russian Federation on 2012-07-31

Patient:

Reactions: Vomiting, Acute Leukaemia, Febrile Neutropenia, Treatment Failure, Neutropenia, Toxicity To Various Agents, Neoplasm, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin Hydrochloride
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Dacarbazine
    Indication: Hodgkin's Disease

Cyclophosphamide
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Indication: Hodgkin's Disease

Prednisone
    Indication: Hodgkin's Disease

Vinblastine Sulfate
    Indication: Hodgkin's Disease

Vincristine
    Indication: Hodgkin's Disease

Chemoradiation
    Indication: Hodgkin's Disease



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-30

Patient:

Reactions: B-Cell Lymphoma Refractory, Toxicity To Various Agents, Treatment Failure, Lymphoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Prednisolone
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Russian Federation on 2012-07-26

Patient:

Reactions: Vomiting, Acute Leukaemia, Febrile Neutropenia, Treatment Failure, Neutropenia, Toxicity To Various Agents, Neoplasm, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Vinblastine Sulfate
    Indication: Hodgkin's Disease

Dacarbazine
    Indication: Hodgkin's Disease

Prednisone
    Indication: Hodgkin's Disease

Chemoradiation
    Indication: Hodgkin's Disease

Cyclophosphamide
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Vincristine
    Indication: Hodgkin's Disease



Possible Vincristine side effects in

Reported by a physician from Italy on 2012-07-20

Patient:

Reactions: Anaemia, Febrile Neutropenia, Toxicity To Various Agents, Diffuse Large B-Cell Lymphoma Recurrent, Mucosal Inflammation, Neurotoxicity, Sepsis, Adverse Event, Cardiotoxicity, Neutropenia, Thrombocytopenia, Diffuse Large B-Cell Lymphoma, Lymphoma, Septic Shock

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 750 mg/m2 on day 1 for chop and 750 mg/m2 on day 2 for r-chop
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: 50 mg/m2 on day 1 for chop and 50 mg/m2 on day 2 for r-chop
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: 375 mg/m2 on day 1 for r-chop
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: 1.4 mg/m2 on day 1 for chop and 1.4 mg/m2 on day 2 for r-chop upto a maximum dose of 2 mg
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Dosage: 100 mg on days 1-5 for chop and r-chop
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Neupogen



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-07-10

Patient:

Reactions: Cytogenetic Abnormality, Adverse Event, Toxicity To Various Agents, Multiple Myeloma, Blood Creatinine Abnormal, Polyneuropathy

Drug(s) suspected as cause:
Bortezomib
    Dosage: days 1,4,8,11 1.3 mg/m2, 2 weekly maintenace dose in arm b
    Indication: Multiple Myeloma

Vincristine
    Indication: Multiple Myeloma

Adriamycin PFS
    Indication: Multiple Myeloma

Doxorubicin Hydrochloride
    Dosage: day 1-4
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: days 1-4, 9-12, 17-20 (pad) or unspecified dose in vad
    Indication: Multiple Myeloma

Melphalan Hydrochloride
    Dosage: one hovon or two gmmg high dose melphalan with autologous stem cell transpalnt
    Indication: Multiple Myeloma

Other drugs received by patient: Thalidomide



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-06-27

Patient:

Reactions: Adverse Event, Toxicity To Various Agents, Multiple Myeloma, Polyneuropathy

Drug(s) suspected as cause:
Vincristine
    Indication: Multiple Myeloma

Adriamycin PFS
    Indication: Multiple Myeloma

Bortezomib
    Dosage: days 1,4,8,11 1.3 mg/m2, 2 weekly maintenace dose in arm b
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: days 1-4, 9-12, 17-20 (pad) or unspecified dose in vad
    Indication: Multiple Myeloma

Melphalan Hydrochloride
    Dosage: one hovon or two gmmg high dose melphalan with autologous stem cell transpalnt
    Indication: Multiple Myeloma

Doxorubicin Hydrochloride
    Dosage: day 1-4
    Indication: Multiple Myeloma

Other drugs received by patient: Thalidomide



Possible Vincristine side effects in

Reported by a physician from Italy on 2012-06-27

Patient:

Reactions: Death, Toxicity To Various Agents, Diffuse Large B-Cell Lymphoma, Chemotherapy

Adverse event resulted in: death

Drug(s) suspected as cause:
Radiotherapy
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma

Unspecifed Medications
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in

Reported by a physician from France on 2012-06-27

Patient:

Reactions: Febrile Neutropenia, Neutropenia, Toxicity To Various Agents, Diffuse Large B-Cell Lymphoma, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Rituximab
    Dosage: on day 1, every 21 days for 6 cycles
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1, every 21 days for 6 cycles
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: on day 1, every 21 days for 6 cycles
    Indication: Diffuse Large B-Cell Lymphoma

Granulocyte Colony Stimulating Factor
    Indication: Diffuse Large B-Cell Lymphoma

Prednisolone
    Dosage: on days 1-5, every 21 days for 6 cycles
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: on day 1, every 21 days for 6 cycles
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-22

Patient:

Reactions: Performance Status Decreased, Pain, Abdominal Pain Upper, Fatigue, Neutropenic Infection, Thrombocytopenia, Hallucination, Dyspnoea, Vomiting, Nausea, Hyperglycaemia, Haemoglobin Abnormal, Pancytopenia, Febrile Neutropenia, Toxicity To Various Agents, Haemoglobin, Neutropenia, Diffuse Large B-Cell Lymphoma, Cardiovascular Disorder, Leukopenia, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Vincristine
    Dosage: 6-8 cycles
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma

Granulocyte Macrophage Colony Stim Factor
    Dosage: days 3-10
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: 6-8 cycles
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: 6-8 cycles
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: 6-8 cycles
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Anti-Emetics; Dapsone; Trimethoprim + Sulfamethoxazole



Possible Vincristine side effects in 55 year old male

Reported by a physician from Belgium on 2012-06-21

Patient: 55 year old male

Reactions: Bone Marrow Failure, Toxicity To Various Agents, Aplasia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Folic Acid
    Dosage: 200 mg;iv
    Indication: Metastases To Meninges
    Start date: 2009-07-03
    End date: 2009-07-05

Methylprednisolone
    Dosage: 100 mg;iv
    Indication: Metastases To Meninges
    Start date: 2009-07-02
    End date: 2009-07-05

Cyclophosphamide
    Dosage: 460 mg;iv
    Indication: Metastases To Meninges
    Start date: 2009-07-03
    End date: 2009-07-05

Rituximab (Rituximab)
    Dosage: 693 mg;iv
    Indication: Metastases To Meninges
    Start date: 2009-07-01
    End date: 2009-07-01

Methotrexate Sodium
    Dosage: 5500 mg;iv
    Indication: Metastases To Meninges
    Start date: 2009-07-02
    End date: 2009-07-02

Adriamycin PFS
    Dosage: 110 mg;iv
    Indication: Metastases To Meninges
    Start date: 2009-07-03
    End date: 2009-07-03

Vincristine
    Dosage: 2 mg;iv
    Indication: Metastases To Meninges
    Start date: 2009-07-02
    End date: 2009-07-02

Depocyt
    Dosage: 50 mg;inth
    Indication: Metastases To Meninges
    Start date: 2009-07-03
    End date: 2009-07-03



Possible Vincristine side effects in male

Reported by a individual with unspecified qualification from Netherlands on 2012-06-20

Patient: male, weighing 74.1 kg (163.0 pounds)

Reactions: Neoplasm Progression, Fall, Loss of Consciousness, Disease Progression, Multi-Organ Failure, Acute Myocardial Infarction, Decreased Appetite, Gastrointestinal Ulcer Haemorrhage, Faecal Incontinence, Toxicity To Various Agents, Pulmonary Sepsis, Lung Disorder, Cardiac Failure, Drug-Induced Liver Injury, Sensory Disturbance, Diffuse Large B-Cell Lymphoma

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Mabthera
    Dosage: 710 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2010-11-11

Cyclophosphamide
    Dosage: 1430 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2010-11-11

Neulasta
    Dosage: 6 mg, unk
    Indication: B-Cell Lymphoma

Doxorubicin HCL
    Dosage: unk
    Indication: B-Cell Lymphoma
    Start date: 2010-11-11

Vincristine
    Dosage: 1 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2010-11-11

Prednisone TAB
    Dosage: 500 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2010-11-11

Other drugs received by patient: Diclofenac Sodium; Diflucan; Cotrim; Piperacillin and Tazobactam; Valacyclovir Hydrochloride; Fenazepam; Valacyclovir Hydrochloride; Cotrim; Allopurinol; Omeprazole; Ondansetron; Fluconazole



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-06-14

Patient:

Reactions: Toxicity To Various Agents, Diffuse Large B-Cell Lymphoma Recurrent, Haematotoxicity

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: B-Cell Lymphoma

Rituximab
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: B-Cell Lymphoma

Prednisolone
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: B-Cell Lymphoma

Rituximab
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: B-Cell Lymphoma

Cyclophosphamide
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: Diffuse Large B-Cell Lymphoma

Prednisolone
    Dosage: it was performed in a group which was given r-chop for 14 days and r-chop for 21 days.
    Indication: B-Cell Lymphoma



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-04

Patient:

Reactions: Sepsis, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Methotrexate
    Dosage: intrathecal
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia

Elspar
    Indication: Lymphocytic Leukaemia

Prednisolone
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-04

Patient:

Reactions: Sepsis, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Elspar
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia

Prednisolone
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: intrathecal
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in

Reported by a physician from Germany on 2012-06-01

Patient:

Reactions: Respiratory Disorder, Pain, Myelodysplastic Syndrome, Pyrexia, Neoplasm, Death, Completed Suicide, Thrombocytopenia, Vomiting, Nausea, Anaemia, Acute Myeloid Leukaemia, Toxicity To Various Agents, Haematotoxicity, Hodgkin's Disease, Mucosal Inflammation, Accident, Alopecia, Gastrointestinal Disorder, Nervous System Disorder, non-Hodgkin's Lymphoma, Cardiovascular Disorder, Leukopenia, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Vincristine
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Indication: Hodgkin's Disease

Prednisone TAB
    Indication: Hodgkin's Disease

Doxorubicin HCL
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Indication: Hodgkin's Disease

Other drugs received by patient: Radiotherapy



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-05-31

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Cytarabine
    Dosage: 1 in 1 wk, intrathecal
    Indication: Acute Lymphocytic Leukaemia

Prednisolone
    Dosage: 1 in 1 wk, intrathecal
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: 1 in 1 wk, intrathecal
    Indication: Acute Lymphocytic Leukaemia

Mercaptopurine
    Dosage: 50 mg/m2 milligram(s) / sq. meter, 1 in 1 d;
    Indication: Acute Lymphocytic Leukaemia

Elspar
    Dosage: 10000 me/m2 weekly for 18 doses
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone
    Dosage: 6 mg/m2 milligram(s)/sq. meter, for 36 days;
    Indication: Acute Lymphocytic Leukaemia

Daunorubicin HCL
    Dosage: 45 mg/m2 milligram(s) / sq. meter, for 2 doses
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Dosage: 2 mg milligram(s), for 5 doses
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in

Reported by a individual with unspecified qualification from Spain on 2012-05-30

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Prednisone TAB
    Indication: Acute Lymphocytic Leukaemia

Elspar
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-05-30

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Elspar
    Indication: Acute Lymphocytic Leukaemia

Prednisone TAB
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-05-11

Patient:

Reactions: Neurotoxicity, Toxicity To Various Agents, Diffuse Large B-Cell Lymphoma Recurrent, Cardiotoxicity, Chemotherapy, Haematotoxicity, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Methotrexate
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Bleomycin Sulfate
    Indication: Diffuse Large B-Cell Lymphoma

Rituxan
    Indication: Diffuse Large B-Cell Lymphoma

VM-26
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from China on 2012-05-11

Patient:

Reactions: Hypersensitivity, Petechiae, Off Label Use, Neurotoxicity, Hepatotoxicity, Granulocytopenia, Bone Marrow Failure, White Blood Cell Count Decreased, Gastrointestinal Toxicity, Anaemia, Nephropathy Toxic, Urinary Tract Infection, Toxicity To Various Agents, Soft Tissue Infection, Sepsis, Platelet Count Decreased, Infection

Drug(s) suspected as cause:
Mesna
    Indication: Acute Myeloid Leukaemia

Epirubicin
    Indication: non-Hodgkin's Lymphoma

Epirubicin
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Indication: non-Hodgkin's Lymphoma

Cyclophosphamide
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: non-Hodgkin's Lymphoma

Methotrexate
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Indication: Acute Lymphocytic Leukaemia

Vindesine
    Indication: non-Hodgkin's Lymphoma

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma

Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Vindesine
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone
    Indication: non-Hodgkin's Lymphoma

Doxorubicin HCL
    Indication: non-Hodgkin's Lymphoma

Doxorubicin HCL
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Indication: non-Hodgkin's Lymphoma

Mesna
    Indication: non-Hodgkin's Lymphoma

Other drugs received by patient: Leucovorin Calcium



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-05-10

Patient:

Reactions: Neurotoxicity, Toxicity To Various Agents, Diffuse Large B-Cell Lymphoma Recurrent, Cardiotoxicity, Chemotherapy, Haematotoxicity, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Methotrexate
    Indication: Diffuse Large B-Cell Lymphoma

VM-26
    Indication: Diffuse Large B-Cell Lymphoma

Bleomycin Sulfate
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in

Reported by a individual with unspecified qualification from United States on 2012-04-24

Patient:

Reactions: Gastrointestinal Toxicity, Febrile Neutropenia, Toxicity To Various Agents, Neurotoxicity, Sepsis, Neutropenia, Cardiotoxicity, Thrombocytopenia, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Mabthera
    Indication: Malignant Lymphoid Neoplasm

Vincristine
    Indication: Malignant Lymphoid Neoplasm

Cyclophosphamide
    Indication: Malignant Lymphoid Neoplasm

Doxorubicin HCL
    Indication: Malignant Lymphoid Neoplasm

Etoposide
    Indication: Malignant Lymphoid Neoplasm

Prednisone TAB
    Administration route: Oral
    Indication: Malignant Lymphoid Neoplasm

Fludarabine Phosphate
    Indication: Malignant Lymphoid Neoplasm



Possible Vincristine side effects in

Reported by a individual with unspecified qualification from Spain on 2012-04-20

Patient:

Reactions: Febrile Neutropenia, Neutropenia, Toxicity To Various Agents

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Indication: non-Hodgkin's Lymphoma

Prednisone
    Indication: non-Hodgkin's Lymphoma

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma

Mabthera
    Indication: non-Hodgkin's Lymphoma

Doxorubicin Hydrochloride
    Indication: non-Hodgkin's Lymphoma



Possible Vincristine side effects in male

Reported by a physician from United States on 2012-04-13

Patient: male, weighing 63.0 kg (138.7 pounds)

Reactions: Atelectasis, Cardiomegaly, Malaise, Fatigue, Oral Candidiasis, Hypocalcaemia, Pleural Effusion, Dizziness, Pulmonary Oedema, Blood Sodium Decreased, White Blood Cell Count Decreased, Pneumonia, Hypotension, Anaemia, Supraventricular Tachycardia, Toxicity To Various Agents, Lobar Pneumonia, Escherichia Test Positive, Blood Potassium Decreased, Heart Rate Increased, Dehydration, Hypophagia, Platelet Count Decreased, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 50 mg/m2, on day 1 of a 21-day cycle
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2009-01-23
    End date: 2009-03-13

Prednisone TAB
    Dosage: 100 mg, on days 1 through 5 of a 21-day cycle
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2009-01-23
    End date: 2009-03-13

Rituximab
    Dosage: 375 mg/m2, on day 1 of a 21-day cycle
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2009-01-23
    End date: 2009-03-13

Enzastaurine
    Dosage: 1125 mg, loading dose, on day 2
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2009-01-24
    End date: 2009-01-24

Vincristine
    Dosage: 1.4 mg/m2, on day 1 of a 21-day cycle
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2009-01-23
    End date: 2009-03-13

Cyclophosphamide
    Dosage: 750 mg/m2, on day 1 of a 21-day cycle
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2009-01-23
    End date: 2009-03-13

Enzastaurine
    Dosage: 500 mg, daily
    Administration route: Oral
    Start date: 2009-01-25
    End date: 2009-03-19

Other drugs received by patient: Hydromorphone; Marinol; Megestrol; Prednisone; Fentanyl; Zofran; Omeprazole; Iron



Possible Vincristine side effects in

Reported by a physician from Germany on 2012-04-12

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate

Vincristine

Prednisone TAB

Procarbazine Hydrochloride

Cyclophosphamide

Etoposide

Doxorubicin HCL



Possible Vincristine side effects in

Reported by a individual with unspecified qualification from Germany on 2012-04-12

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide

Procarbazine Hydrochloride

Etoposide

Bleomycin Sulfate

Doxorubicin HCL

Vincristine

Prednisone TAB



Possible Vincristine side effects in

Reported by a physician from Germany on 2012-04-12

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Etoposide

Prednisone TAB

Cyclophosphamide

Procarbazine Hydrochloride

Vincristine

Doxorubicin HCL

Bleomycin Sulfate



Possible Vincristine side effects in

Reported by a individual with unspecified qualification from Germany on 2012-04-12

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL

Procarbazine Hydrochloride

Etoposide

Vincristine

Cyclophosphamide

Bleomycin Sulfate

Prednisone TAB



Possible Vincristine side effects in

Reported by a physician from Germany on 2012-04-12

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide

Etoposide

Procarbazine Hydrochloride

Prednisone TAB

Doxorubicin HCL

Bleomycin Sulfate

Vincristine



Possible Vincristine side effects in

Reported by a individual with unspecified qualification from Germany on 2012-04-12

Patient:

Reactions: Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide

Vincristine

Doxorubicin HCL

Prednisone TAB

Bleomycin Sulfate

Etoposide

Procarbazine Hydrochloride



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