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Vincristine (Vincristine) - Pyrexia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Pyrexia (111)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Vincristine where reactions include pyrexia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 111   Next >>

Possible Vincristine side effects in 49 year old male

Reported by a physician from Norway on 2012-08-27

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Lung Infiltration, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Vincristine
    Dosage: on day 8
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Dosage: on day 8
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Doxorubicin Hydrochloride
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Prednisolone
    Dosage: on day 1 to 14 every 21 day cycle treatment for 6 cycles
    Administration route: Oral
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Dosage: on day 1,for standard cycles

Cyclophosphamide
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the standard cycles, day 1 to 3
    Indication: Hodgkin's Disease

Cyclophosphamide
    Dosage: for standard cycles on day 1

Procarbazine Hydrochloride
    Dosage: day 1 to 7
    Administration route: Oral
    Indication: Hodgkin's Disease



Possible Vincristine side effects in 49 year old male

Reported by a physician from Norway on 2012-08-24

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Lung Infiltration, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Dosage: on day 8
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Cyclophosphamide
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the escalated cycles on day 1 to 3

Cyclophosphamide
    Dosage: for standard cycles on day 1

Doxorubicin Hydrochloride
    Dosage: on day 1,for standard cycles

Vincristine
    Dosage: on day 8
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Dosage: day 1 to 7
    Administration route: Oral
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Dosage: for escalated cycles on day 1
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the standard cycles, day 1 to 3
    Indication: Hodgkin's Disease

Prednisolone
    Dosage: on day 1 to 14 every 21 day cycle treatment for 6 cycles
    Administration route: Oral
    Indication: Hodgkin's Disease



Possible Vincristine side effects in 49 year old male

Reported by a physician from Norway on 2012-08-23

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Septic Shock, Lung Infiltration

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide

Doxorubicin Hydrochloride

Etoposide

Cyclophosphamide

Doxorubicin Hydrochloride

Procarbazine Hydrochloride
    Administration route: Oral

Bleomycin Baxter 15 000 IE Lyofilisat TIL Injeksjonsv?ske / Infusjonsv?s

Etoposide

Vincristine

Prednisolone
    Administration route: Oral



Possible Vincristine side effects in 17 year old male

Reported by a physician from Poland on 2012-08-23

Patient: 17 year old male

Reactions: Rhabdomyolysis, Disseminated Intravascular Coagulation, Pancytopenia, Pyrexia, Renal Failure, Neutropenia, Clostridial Infection, Septic Shock

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cefepime

Meropenem

Vancocin Hydrochloride

Ifosfamide
    Indication: Ewing's Sarcoma Metastatic

Netromycin

Doxorubicin Hydrochloride
    Indication: Ewing's Sarcoma

Etoposide
    Indication: Ewing's Sarcoma Metastatic

Metronidazole

Vincristine
    Indication: Ewing's Sarcoma Metastatic

Other drugs received by patient: Fluconazole; Caspofungin Acetate



Possible Vincristine side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16

Patient: female, weighing 87.8 kg (193.2 pounds)

Reactions: Neuropathy Peripheral, Upper Respiratory Tract Infection, Urinary Tract Infection, Pleural Effusion, Pyrexia, Leukocytosis, Sinusitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 40 mg, unk
    Administration route: Oral
    Indication: Mantle Cell Lymphoma

Cytarabine
    Dosage: 1.87 g, cyclic
    Indication: Mantle Cell Lymphoma

Velcade
    Dosage: 0.7 mg/m2, cyclic
    Start date: 2012-03-19

Vincristine
    Dosage: 2 mg, cyclic
    Indication: Mantle Cell Lymphoma

Velcade
    Dosage: 2.77 mg, cyclic
    Indication: Mantle Cell Lymphoma
    Start date: 2011-12-31

Velcade
    Dosage: 0.7 mg/m2, cyclic

Velcade
    Dosage: 0.7 mg/m2, cyclic
    Start date: 2012-02-26

Rituximab
    Dosage: 1 mg/m2, cyclic
    Indication: Mantle Cell Lymphoma

Cyclophosphamide
    Indication: Mantle Cell Lymphoma

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, unk
    Indication: Mantle Cell Lymphoma

Methotrexate
    Indication: Mantle Cell Lymphoma

Mesna
    Dosage: 600 mg/m2, unk
    Indication: Mantle Cell Lymphoma

Other drugs received by patient: Sennosides A+B; Nystatin; Diphenhydramine Hydrochloride; Neupogen; Fluconazole; Zofran; Valtrex; Sodium Chloride; Meperidine HCL; Potassium Chloride; Leucovorin Calcium; Zofran; Sodium Chloride; Sodium Chloride; Sodium Chloride; Heparin; Leucovorin Calcium; Allopurinol; Lovenox; Morphine; Senokot; Cipro / 00042702 /; Lovenox; Prednisolone Acetate; Stomatologicals, Mouth Preparations; Tramadol; Sodium Bicarbonate



Possible Vincristine side effects in 61 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: 61 year old female

Reactions: Mucosal Inflammation, Nausea, Pyrexia, Diffuse Large B-Cell Lymphoma Recurrent, Oral Herpes

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Prednisolone
    Indication: Diffuse Large B-Cell Lymphoma

Etoposide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Bleomycin Sulfate
    Indication: Diffuse Large B-Cell Lymphoma

Methotrexate
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in 46 year old female

Reported by a individual with unspecified qualification from United States on 2012-08-08

Patient: 46 year old female

Reactions: Dyspnoea, Pain in Extremity, Myelodysplastic Syndrome, General Physical Health Deterioration, Pyrexia, Pulmonary Haemorrhage, Zygomycosis, Diarrhoea, Skin Discolouration, Central Nervous System Infection, Small Intestinal Haemorrhage, Cough

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Dosage: 400 ug, intravenous, every two months
    Indication: Diffuse Large B-Cell Lymphoma

Melphalan (Melphalan) (Melphalen)
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab (Rituximab) (Rituximab)
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Idarubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Melphalan Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Cytarabine
    Indication: Diffuse Large B-Cell Lymphoma

Carmustine
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Carmustine
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab (Rituximab) (Rituximab)
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in 82 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-30

Patient: 82 year old female

Reactions: Confusional State, Pyrexia, Lymphoma

Drug(s) suspected as cause:
Mabthera
    Indication: B-Cell Lymphoma

Cyclophosphamide
    Indication: B-Cell Lymphoma

Prednisolone
    Indication: B-Cell Lymphoma

Vincristine
    Indication: B-Cell Lymphoma

Other drugs received by patient: Methotrexate



Possible Vincristine side effects in 17 year old male

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-07-23

Patient: 17 year old male

Reactions: Abdominal Pain, Rhabdomyolysis, Pain in Extremity, Disseminated Intravascular Coagulation, Chromaturia, Pancytopenia, Pyrexia, Renal Failure, Renal Impairment, Diarrhoea, Clostridial Infection, Septic Shock

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Etoposide
    Indication: Ewing's Sarcoma Metastatic

Ifosfamide
    Indication: Ewing's Sarcoma Metastatic

Cefepime
    Indication: Pyrexia

Vincristine
    Indication: Ewing's Sarcoma Metastatic

Doxorubicin HCL
    Indication: Ewing's Sarcoma Metastatic

Netilmicin Sulfate
    Indication: Pyrexia



Possible Vincristine side effects in

Reported by a physician from United Kingdom on 2012-07-17

Patient:

Reactions: Abdominal Pain, Tachycardia, Skin Toxicity, Pyrexia, Fatigue, Neuropathy Peripheral, Hepatotoxicity, Adverse Event, Dizziness, Oedema, Hallucination, Vomiting, Nausea, Gastrointestinal Toxicity, Neutropenic Sepsis, Nephropathy Toxic, Hypotension, Condition Aggravated, Adult T-Cell Lymphoma / Leukaemia, Mucosal Inflammation, Lung Disorder, Infection, Infusion Related Reaction

Adverse event resulted in: death

Drug(s) suspected as cause:
Hydrocortisone
    Indication: Adult T-Cell Lymphoma / Leukaemia

Doxorubicin HCL
    Dosage: on day 1 of 21 day, (cycle 1-5)

Cytarabine
    Indication: Adult T-Cell Lymphoma / Leukaemia

Cyclophosphamide
    Dosage: on day 1 of 21 day cycle, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Zenapax
    Dosage: on days 7 and 14 on cycle 1 of 21 day cycle
    Indication: Adult T-Cell Lymphoma / Leukaemia

Vincristine
    Dosage: (maximum 2 mg) on day 1 of 21 day cycle, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Prednisolone
    Dosage: on days 1-5 of 21 day cycle, (cycle 1-5)
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia

Methotrexate
    Indication: Adult T-Cell Lymphoma / Leukaemia

Radiotherapy
    Indication: Adult T-Cell Lymphoma / Leukaemia

Doxorubicin HCL
    Dosage: on day 1 of 21 day, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Other drugs received by patient: Acyclovir; Thiabendazole; Cotrim; Itraconazole



Possible Vincristine side effects in

Reported by a physician from United Kingdom on 2012-07-10

Patient:

Reactions: Abdominal Pain, Skin Toxicity, Tachycardia, Pyrexia, Fatigue, Neuropathy Peripheral, Hepatotoxicity, Adverse Event, Oedema, Dizziness, Hallucination, Vomiting, Gastrointestinal Toxicity, Nausea, Neutropenic Sepsis, Nephropathy Toxic, Hypotension, Adult T-Cell Lymphoma / Leukaemia, Condition Aggravated, Mucosal Inflammation, Lung Disorder, Infection, Infusion Related Reaction

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on day 1 of 21 day cycle, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Prednisolone
    Dosage: on days 1-5 of 21 day cycle, (cycle 1-5)
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia

Cytarabine
    Indication: Adult T-Cell Lymphoma / Leukaemia

Doxorubicin HCL
    Dosage: on day 1 of 21 day, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Vincristine
    Dosage: (maximum 2 mg) on day 1 of 21 day cycle, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Methotrexate
    Indication: Adult T-Cell Lymphoma / Leukaemia

Zenapax
    Dosage: on days 7 and 14 on cycle 1 of 21 day cycle
    Indication: Adult T-Cell Lymphoma / Leukaemia

Hydrocortisone
    Indication: Adult T-Cell Lymphoma / Leukaemia

Radiotherapy
    Indication: Adult T-Cell Lymphoma / Leukaemia

Other drugs received by patient: Cotrim; Itraconazole; Thiabendazole; Acyclovir



Possible Vincristine side effects in female

Reported by a consumer/non-health professional from Germany on 2012-07-06

Patient: female, weighing 70.0 kg (154.0 pounds)

Reactions: B-Cell Lymphoma, Anaemia, Urinary Incontinence, Abnormal Behaviour, Pulmonary Embolism, Cognitive Disorder, Pyrexia, Fall, Peripheral Sensory Neuropathy, Post Transplant Lymphoproliferative Disorder, Klebsiella Infection, Cytokine Release Syndrome, Cytomegalovirus Infection, Neutrophil Toxic Granulation Present, Traumatic Haematoma, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Campath
    Dosage: 30 mg, bid
    Start date: 2009-07-23

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-07-23

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-08-20

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-07-07

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-06-23

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-06-23

Filgrastim
    Dosage: 3000 iu, unk
    Start date: 2009-07-26
    End date: 2009-08-27

Campath
    Dosage: 20 mg, qd
    Start date: 2009-07-07

Vincristine
    Dosage: 1 mg, once
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-15

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-08-20

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-09-11

Campath
    Dosage: 30 mg, qd
    Start date: 2009-08-06
    End date: 2009-08-06

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-07-21

Doxorubicin HCL
    Dosage: 80 mg, once
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-23

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-07-07

Filgrastim
    Dosage: unk on days 4 through 13 of course 5
    Start date: 2009-08-20

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-07-21

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-15

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-08-06
    End date: 2009-08-10

Filgrastim
    Dosage: unk on days 4 through 12 of course 6
    Start date: 2009-09-08

Campath
    Dosage: 30 mg, qd
    Start date: 2009-09-11
    End date: 2009-10-22

Cyclophosphamide
    Dosage: 1250 mg, once
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-23

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-09-08
    End date: 2009-09-08

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-08-06
    End date: 2009-08-20

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-09-08
    End date: 2009-09-08

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-07-23

Filgrastim
    Dosage: unk on days 4, 5, 6 of course 1
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-23

Filgrastim
    Dosage: unk on days 4 through 15 of course 2
    Start date: 2009-07-07

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-07-23

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-07-07

Filgrastim
    Dosage: unk on days 4 through 8 and day 13 of course 3
    Start date: 2009-07-23

Filgrastim
    Dosage: unk on days 6 + 7 and days 9 through 12 of course 4
    Start date: 2009-08-06

Doxorubicin HCL
    Dosage: 80 mg, once
    Start date: 2009-08-20

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-07-21

Vincristine

Prednisone
    Dosage: 100 mg, qd for 5 days
    Administration route: Oral
    Start date: 2009-07-23

Prednisone
    Dosage: 100 mg, unk
    Administration route: Oral
    Start date: 2009-09-08
    End date: 2009-09-08

Campath
    Dosage: 10 mg, qd
    Indication: Peripheral T-Cell Lymphoma Unspecified
    Start date: 2009-06-23

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-07-07

Cyclophosphamide
    Dosage: 1200 mg, once
    Start date: 2009-08-06
    End date: 2009-08-20

Vincristine
    Dosage: 2 mg, once
    Start date: 2009-08-06
    End date: 2009-08-20

Filgrastim
    Dosage: 30000 iu, qd
    Start date: 2009-09-11
    End date: 2009-09-19

Other drugs received by patient: Enoxaparin Sodium; Enoxaparin Sodium; Ganciclovir; Metoprolol Tartrate; Trimethoprim + Sulfamethoxazole; Dexamethasone; Antibiotics; Torsemide; Fluticasone Propionate W; Fondaparinux Sodium; Pantoprazole; Ganciclovir; Spiriva



Possible Vincristine side effects in

Reported by a individual with unspecified qualification from Korea, Republic of on 2012-06-26

Patient:

Reactions: Abdominal Pain, Hyperbilirubinaemia, Anaemia, Alanine Aminotransferase Increased, Febrile Neutropenia, Rash, Pyrexia, Peripheral Sensory Neuropathy, Diarrhoea, Alopecia, Aspartate Aminotransferase Increased, Neutropenia, Asthenia, Thrombocytopenia

Drug(s) suspected as cause:
Vincristine
    Dosage: given on day 1 of every cycle; dose: 1.4 mg/m2 ( maximum 2.0 mg)
    Indication: B-Cell Lymphoma

Prednisolone
    Dosage: given on days 1 to 5 of every cycle (repeated every 3 weeks)
    Administration route: Oral
    Indication: B-Cell Lymphoma

Mabthera
    Dosage: on day 1 of every cycle
    Indication: B-Cell Lymphoma

Cyclophosphamide
    Dosage: given on day 1 of each cycle
    Indication: B-Cell Lymphoma



Possible Vincristine side effects in 71 year old male

Reported by a physician from United Kingdom on 2012-06-21

Patient: 71 year old male, weighing 79.7 kg (175.3 pounds)

Reactions: Haemoglobin Decreased, Chest Pain, Platelet Count Decreased, Pyrexia, Troponin Increased, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisone TAB
    Administration route: Oral
    Indication: non-Hodgkin's Lymphoma
    Start date: 2009-03-25
    End date: 2009-03-29

Vincristine
    Indication: non-Hodgkin's Lymphoma
    Start date: 2009-03-25
    End date: 2009-03-25

Rituximab
    Indication: non-Hodgkin's Lymphoma
    Start date: 2009-03-25
    End date: 2009-03-25

Gemcitabine
    Indication: non-Hodgkin's Lymphoma
    Start date: 2009-03-25
    End date: 2009-04-01

Neulasta
    Indication: non-Hodgkin's Lymphoma
    Start date: 2009-03-25
    End date: 2009-04-02

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma
    Start date: 2009-03-25
    End date: 2009-03-25

Other drugs received by patient: Tramadol HCL; Metoclopramide; Cotrim



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-21

Patient:

Reactions: Urticaria, Pyrexia, Headache, Oropharyngeal Pain, Constipation, Polyneuropathy, Fatigue, Dyspepsia, Oedema Peripheral, Cough, Dyspnoea, Vomiting, Nausea, Rash, Dysgeusia, Diarrhoea, Alopecia, Neutropenia, Respiratory Tract Infection, Leukopenia, Infection, Infusion Related Reaction

Drug(s) suspected as cause:
Ofatumumab
    Indication: B-Cell Lymphoma

Ofatumumab

Cyclophosphamide
    Indication: B-Cell Lymphoma

Prednisone TAB
    Administration route: Oral
    Indication: B-Cell Lymphoma

Doxorubicin HCL
    Indication: B-Cell Lymphoma

Vincristine
    Indication: B-Cell Lymphoma

Other drugs received by patient: Acetaminophen; Cetirizine; Glucocorticoids



Possible Vincristine side effects in 49 year old male

Reported by a physician from Norway on 2012-06-14

Patient: 49 year old male

Reactions: Off Label Use, Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Lung Infiltration, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Etoposide

Bleomycin Sulfate

Doxorubicin HCL

Vincristine

Prednisolone
    Administration route: Oral

Procarbazine Hydrochloride
    Administration route: Oral

Cyclophosphamide



Possible Vincristine side effects in male

Reported by a physician from United States on 2012-06-12

Patient: male, weighing 14.6 kg (32.1 pounds)

Reactions: Large Intestine Perforation, Vomiting, Dehydration, Pancytopenia, Pyrexia, Asthenia, Abdominal Tenderness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: total dose administered 2.76 mg

Dexamethasone
    Dosage: total dose administered 80 mg

PEG-L-Asparaginase (Pegaspargase, Oncospar)
    Dosage: total dose administered 1550 unit

Cytarabine
    Dosage: total dose administered 70 mg

Methotrexate
    Dosage: total dose administered 12 mg



Possible Vincristine side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-06-11

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Lung Infiltration, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 35mg/m2,on d1 for escalated cycles
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Dosage: on d8
    Indication: Hodgkin's Disease

Etoposide
    Dosage: 100mg/m2 for the standard cycles d1 to 3; 200mg/m2 for the escalated cycles from d1-3 iv
    Indication: Hodgkin's Disease

Cyclophosphamide
    Dosage: 650mg/m2 standard cycles 1250 for the escalated cycles
    Indication: Hodgkin's Disease

Vincristine
    Dosage: on d8
    Indication: Hodgkin's Disease

Prednisolone
    Dosage: on days 1 to 14 in every 21 day cycle treatment for 6 cycles
    Administration route: Oral
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Dosage: day1-7
    Administration route: Oral
    Indication: Hodgkin's Disease



Possible Vincristine side effects in 17 year old female

Reported by a physician from United States on 2012-06-08

Patient: 17 year old female, weighing 47.6 kg (104.7 pounds)

Reactions: Blood Bilirubin Increased, Pyrexia, Caecitis, Loss of Consciousness, Oedema Peripheral, Pulmonary Oedema, Hypocalcaemia, Acute Respiratory Distress Syndrome, Melaena, Hypertriglyceridaemia, Epistaxis, Dysphagia, Anaemia, Hyperglycaemia, General Physical Health Deterioration, Eating Disorder, Tremor, Cerebral Infarction, Depressed Level of Consciousness, Neutropenia, Confusional State, Dyskinesia, Somnolence, Splenic Infarction, Hypokalaemia, Pleural Effusion, White Blood Cell Count Decreased, Cerebrovascular Accident, Ascites, Diarrhoea, Hypophagia, Hypoalbuminaemia, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Dosage: 60mgm2 cyclic
    Administration route: Oral
    Indication: T-Cell Type Acute Leukaemia

Vincristine
    Dosage: 1.5mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Cyclophosphamide
    Dosage: 1000mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Methotrexate
    Indication: T-Cell Type Acute Leukaemia

Oncaspar
    Indication: T-Cell Type Acute Leukaemia

Nelarabine
    Dosage: 650mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-04-13

Cytarabine
    Dosage: 75mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Dalteparin Sodium
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Nystatin; Lansoprazole; Insulin Aspart; Piperacillin and Tazobactam; Vancomycin; Voriconazole



Possible Vincristine side effects in 63 year old male

Reported by a physician from Germany on 2012-06-07

Patient: 63 year old male

Reactions: Dehydration, Febrile Neutropenia, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Indication: non-Hodgkin's Lymphoma

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma

Mabthera
    Indication: non-Hodgkin's Lymphoma

Doxorubicin HCL
    Indication: non-Hodgkin's Lymphoma

Prednisone TAB
    Indication: non-Hodgkin's Lymphoma



Possible Vincristine side effects in 49 year old male

Reported by a physician from Norway on 2012-06-05

Patient: 49 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Bone Marrow Failure, Pyrexia, Lung Infiltration, Septic Shock, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: for standard cycles on day 1
    Indication: Hodgkin's Disease

Vincristine
    Dosage: on day 8
    Indication: Hodgkin's Disease

Prednisolone
    Dosage: on day 1 to 14
    Administration route: Oral
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Dosage: day 1 to 7
    Administration route: Oral
    Indication: Hodgkin's Disease

Doxorubicin HCL
    Dosage: for escalated cycles on day 1

Etoposide
    Dosage: for the standard cycles, day 1 to 3

Bleomycin Sulfate
    Dosage: on day 8
    Indication: Hodgkin's Disease

Etoposide
    Dosage: for the escalated cycles on day 1 to 3
    Indication: Hodgkin's Disease

Cyclophosphamide
    Dosage: for escalated cycles on day 1

Doxorubicin HCL
    Dosage: for standard cycles
    Indication: Hodgkin's Disease



Possible Vincristine side effects in female

Reported by a physician from United States on 2012-06-05

Patient: female

Reactions: Neutropenia, Device Related Infection, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: itrc
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-23
    End date: 2012-04-23

Dasatinib
    Dosage: 45 milligram;
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-30

Cytarabine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-16

Daunorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-30

Dexamethasone
    Dosage: 2/1 day
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-29

Pegaspargase
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-19
    End date: 2012-04-19

Vincristine
    Dosage: 7 day
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-30

Other drugs received by patient: Furosemide; Nystatin; Zantac; Ondansetron



Possible Vincristine side effects in

Reported by a physician from Germany on 2012-06-01

Patient:

Reactions: Respiratory Disorder, Pain, Myelodysplastic Syndrome, Pyrexia, Neoplasm, Death, Completed Suicide, Thrombocytopenia, Vomiting, Nausea, Anaemia, Acute Myeloid Leukaemia, Toxicity To Various Agents, Haematotoxicity, Hodgkin's Disease, Mucosal Inflammation, Accident, Alopecia, Gastrointestinal Disorder, Nervous System Disorder, non-Hodgkin's Lymphoma, Cardiovascular Disorder, Leukopenia, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Vincristine
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Indication: Hodgkin's Disease

Prednisone TAB
    Indication: Hodgkin's Disease

Doxorubicin HCL
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Indication: Hodgkin's Disease

Other drugs received by patient: Radiotherapy



Possible Vincristine side effects in female

Reported by a physician from France on 2012-05-29

Patient: female, weighing 40.0 kg (88.0 pounds)

Reactions: Febrile Neutropenia, General Physical Health Deterioration, Pyrexia, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-13

Prednisone TAB
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-13

Adriamycin PFS
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-13

Istodax
    Dosage: 14 milligram
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-12

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-13



Possible Vincristine side effects in female

Reported by a physician from United States on 2012-05-25

Patient: female

Reactions: Pyrexia, Device Related Infection, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cytarabine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-16

Dasatinib
    Dosage: 45 milligram;
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-30

Pegaspargase
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-19
    End date: 2012-04-19

Vincristine
    Dosage: 7 day
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-30

Dexamethasone
    Dosage: 2/1 day
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-29

Daunorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-30

Methotrexate
    Dosage: itrc
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-23
    End date: 2012-04-23

Other drugs received by patient: Zantac; Nystatin; Ondansetron; Furosemide



Possible Vincristine side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-25

Patient: female, weighing 14.9 kg (32.8 pounds)

Reactions: Anaemia, Hyponatraemia, Rash, Pyrexia, Ascites, Abdominal Pain Upper, Abdominal Compartment Syndrome, Respiratory Failure, Pneumonia Herpes Viral, Bone Marrow Failure, Neutropenia, Thrombocytopenia, Cardiac Arrest, Septic Shock, Infection in AN Immunocompromised Host

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: .99 mg

Methotrexate
    Dosage: 24.5 mg

Dexamethasone
    Dosage: 17.5 ml

Mercaptopurine
    Dosage: 460 mg



Possible Vincristine side effects in 10 year old male

Reported by a physician from United States on 2012-05-24

Patient: 10 year old male, weighing 22.3 kg (49.1 pounds)

Reactions: Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 27 mg, qd on day 1 and 5
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-03-31
    End date: 2012-05-01

Methylprednisolone Acetate
    Dosage: 9.7 mg, q8h on day 4 to day 32
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-03

Etoposide
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-10

Afinitor
    Dosage: 2 mg, qd on day 1 to day 32
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-03-31
    End date: 2012-05-01

Oncaspar
    Dosage: 2275 iu, qd on days 4 to 32
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-03-31
    End date: 2012-05-01

Vincristine
    Dosage: 1.4 mg, qd on day 4, 11, 18 and 25
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-03-31
    End date: 2012-05-01

Cytoxan
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-10

Other drugs received by patient: Leucovorin Calcium; Ondansetron; Senna-Mint WAF; Colace; Sulfamethoxypyrazine / Trimethoprim; Ondansetron; Concerta; Calcium Carbonate; Clonidine



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-18

Patient:

Reactions: Urticaria, Headache, Pyrexia, Oropharyngeal Pain, Constipation, Polyneuropathy, Fatigue, Dyspepsia, Oedema Peripheral, Cough, Dyspnoea, Vomiting, Nausea, Rash, Dysgeusia, Diarrhoea, Alopecia, Neutropenia, Respiratory Tract Infection, Leukopenia, Infection, Infusion Related Reaction

Drug(s) suspected as cause:
Vincristine
    Indication: B-Cell Lymphoma

Cyclophosphamide
    Indication: B-Cell Lymphoma

Prednisone
    Administration route: Oral
    Indication: B-Cell Lymphoma

Ofatumumab
    Indication: B-Cell Lymphoma

Doxorubicin HCL
    Indication: B-Cell Lymphoma

Ofatumumab

Other drugs received by patient: Cetirizine; Acetaminophen; Glucocorticoids



Possible Vincristine side effects in 1 year old female

Reported by a physician from United States on 2012-05-10

Patient: 1 year old female, weighing 7.6 kg (16.8 pounds)

Reactions: Dyspnoea, Vomiting, Hypothermia, Nausea, Chills, Pyrexia, Peripheral Sensory Neuropathy, Sinus Bradycardia, Hypokalaemia, Diarrhoea, Ileus, Hypoalbuminaemia, Lung Infiltration, Candidiasis, Influenza Like Illness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: 1.5 mg/m2, cyclic
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2012-03-23
    End date: 2012-03-23

Doxorubicin HCL
    Dosage: 60 mg/m2, cyclic
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2012-03-23
    End date: 2012-03-23

Prednisone TAB
    Dosage: 20 mg/m2, unk
    Administration route: Oral
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2012-03-23
    End date: 2012-03-24

Cytarabine
    Dosage: unk mg, cyclic
    Indication: B Precursor Type Acute Leukaemia
    End date: 2012-03-22

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2012-03-23
    End date: 2012-03-23



Possible Vincristine side effects in male

Reported by a physician from Denmark on 2012-05-08

Patient: male, weighing 81.0 kg (178.2 pounds)

Reactions: Pneumonia, Pulmonary Embolism, Febrile Neutropenia, Pyrexia, Muscle Rupture

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Start date: 2011-04-26

Doxorubicin HCL
    Start date: 2011-04-26

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-08-03

Cyclophosphamide
    Start date: 2011-04-26

Prednisone TAB
    Administration route: Oral
    Start date: 2011-04-26

Neupogen
    Start date: 2011-06-29

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-08-03

Doxorubicin HCL
    Start date: 2011-06-28

Vincristine
    Dosage: dosage form: unspecified
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Start date: 2011-06-28

Rituximab
    Start date: 2011-06-28

Rituximab
    Start date: 2011-05-03

Rituximab
    Start date: 2011-04-26

Rituximab
    Start date: 2011-07-02
    End date: 2011-07-02

Neupogen
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-08-04

Cyclophosphamide
    Dosage: dosage form: unspecified
    Start date: 2011-06-28

Neupogen
    Start date: 2011-04-27

Prednisone TAB
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-08-03

Prednisone TAB
    Administration route: Oral
    Start date: 2011-06-28

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-08-03

Other drugs received by patient: Morphine Sulfate; Morphine; Acyclovir; Sennoside A+B; Lansoprazole; Furosemide; Enoxaparin Sodium; Amlodipine Besylate; Lactulose; Allopurinol; Sulfamethoxazole + Trimethoprim; Movicol / 01625101 /



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