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Vincristine (Vincristine) - Febrile Neutropenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Febrile Neutropenia (261)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Vincristine where reactions include febrile neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 261   Next >>

Possible Vincristine side effects in male

Reported by a physician from Germany on 2012-08-24

Patient: male

Reactions: Febrile Neutropenia, Skin Infection, Neutropenia, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1500 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Doxorubicin Hydrochloride
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Neulasta
    Dosage: 6 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-06
    End date: 2012-04-20

Prednisolone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-21

Rituximab
    Dosage: 750 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-01
    End date: 2012-04-16

Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Other drugs received by patient: MST / 00036302 /; Novalgin / 00169801 /; Rulid; Pantoprazole; Paspertin / 00041902 /; Acyclovir; Electrolytes NOS W / Macrogol 3350; Dipyrone INJ; Metoclopramide; Acyclovir



Possible Vincristine side effects in male

Reported by a physician from United States on 2012-08-22

Patient: male

Reactions: Rectal Haemorrhage, Constipation, Cardiac Disorder, Hospitalisation, Granulocytopenia, Inappropriate Antidiuretic Hormone Secretion, Thrombocytopenia, Cardiac Failure Congestive, Pneumonia, Anaemia, Pancytopenia, Atrial Fibrillation, Febrile Neutropenia, Syncope, Embolism, Sepsis, Dehydration, Asthenia, Mantle Cell Lymphoma Recurrent, Leukopenia, Deep Vein Thrombosis, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Cyclophosphamide
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Mantle Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Mantle Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Mantle Cell Lymphoma



Possible Vincristine side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-22

Patient: male

Reactions: Pneumonia Bacterial, Febrile Neutropenia

Drug(s) suspected as cause:
Cisplatin
    Dosage: unk
    Indication: Thymoma Malignant
    Start date: 2011-08-01

Cyclophosphamide
    Dosage: unk
    Indication: Thymoma Malignant
    Start date: 2011-08-01

Doxorubicin HCL
    Dosage: unk
    Indication: Thymoma Malignant
    Start date: 2011-08-01

Vincristine
    Dosage: unk
    Indication: Thymoma Malignant
    Start date: 2011-08-01



Possible Vincristine side effects in 41 year old male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-21

Patient: 41 year old male

Reactions: Ecthyma, Pseudomonas Infection, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: B-Cell Lymphoma

Doxorubicin HCL
    Indication: B-Cell Lymphoma

Prednisone TAB
    Dosage: unk
    Indication: B-Cell Lymphoma

Rituximab
    Indication: B-Cell Lymphoma

Vincristine
    Indication: B-Cell Lymphoma



Possible Vincristine side effects in male

Reported by a physician from India on 2012-08-17

Patient: male, weighing 65.0 kg (143.0 pounds)

Reactions: Diarrhoea, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Blinded Gp2013
    Dosage: code not broken
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-08-06

Blinded Mabthera
    Dosage: code not broken
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-08-06

Blinded NO Treatment Received
    Dosage: code not broken
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-08-06

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma

Prednisone TAB
    Administration route: Oral
    Indication: non-Hodgkin's Lymphoma

Vincristine
    Indication: non-Hodgkin's Lymphoma



Possible Vincristine side effects in male

Reported by a individual with unspecified qualification from United Kingdom on 2012-08-14

Patient: male, weighing 22.9 kg (50.4 pounds)

Reactions: Vomiting, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dactinomycin
    Start date: 2012-07-04
    End date: 2012-07-04

Doxorubicin Hydrochloride
    Start date: 2012-07-04
    End date: 2012-07-04

Doxorubicin Hydrochloride
    Start date: 2012-07-05
    End date: 2012-07-05

Ifex
    Start date: 2012-07-04
    End date: 2012-07-04

Ifex
    Start date: 2012-07-05
    End date: 2012-07-05

Mesnex
    Start date: 2012-07-04
    End date: 2012-07-04

Mesnex
    Start date: 2012-07-06
    End date: 2012-07-06

Mesnex
    Start date: 2012-07-05
    End date: 2012-07-05

Vincristine
    Start date: 2012-07-04
    End date: 2012-07-04

Vincristine
    Start date: 2012-07-11
    End date: 2012-07-11

Other drugs received by patient: Dexamethasone; Dexamethasone; Moviprep; Ondansetron; Cotrim; Docusate Sodium



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-09

Patient:

Reactions: Dermatitis Allergic, Pneumonia, Angina Pectoris, Febrile Neutropenia, Cognitive Disorder, Hepatitis, Arrhythmia, Interstitial Lung Disease, Gastrointestinal Disorder, Progressive Multifocal Leukoencephalopathy, Cardiac Failure Congestive, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Indication: Diffuse Large B-Cell Lymphoma

Radiotherapy
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-07

Patient:

Reactions: Hospitalisation, Neuropathy Peripheral, Vomiting, Febrile Neutropenia, Neutropenia, Neutrophil Count Decreased, Lymphoma

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Dosage: for 5 days
    Indication: B-Cell Lymphoma

Prednisone
    Dosage: for 5 days
    Indication: Diffuse Large B-Cell Lymphoma

Radiotherapy
    Indication: Diffuse Large B-Cell Lymphoma

Radiotherapy
    Indication: B-Cell Lymphoma

Rituximab
    Indication: B-Cell Lymphoma

Rituximab
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Neupogen



Possible Vincristine side effects in male

Reported by a physician from United States on 2012-08-07

Patient: male

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dasatinib
    Dosage: one day
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-26

Dexamethasone

Doxorubicin Hydrochloride

Methotrexate
    Start date: 2012-05-11

Vincristine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-03

Other drugs received by patient: Ondansetron; Glutamic Acid; Lorazepam; Morphine Sulfate; Bactrim



Possible Vincristine side effects in 41 year old male

Reported by a physician from Canada on 2012-08-03

Patient: 41 year old male

Reactions: Ecthyma, Diarrhoea, Pseudomonas Infection, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: B-Cell Lymphoma Stage IV

Doxorubicin HCL
    Indication: B-Cell Lymphoma Stage IV

Prednisone
    Indication: B-Cell Lymphoma Stage IV

Rituximab
    Indication: B-Cell Lymphoma Stage IV

Vincristine
    Indication: B-Cell Lymphoma Stage IV

Other drugs received by patient: Epogen; Enoxaparin Sodium; Filgrastim



Possible Vincristine side effects in male

Reported by a lawyer from United States on 2012-08-03

Patient: male

Reactions: Tinnitus, Femur Fracture, Osteomyelitis, Oral Cavity Fistula, Erythema, Erectile Dysfunction, Neurotoxicity, Hypoaesthesia Oral, Oedema Peripheral, Carpal Tunnel Syndrome, Radiculopathy, Intervertebral Disc Protrusion, Cellulitis, Gingival Bleeding, Pneumonia, Pain in Extremity, Anaemia, Encephalopathy, Otitis Externa, Nasal Septum Deviation, Abscess JAW, Paraesthesia, Osteosclerosis, Rhinitis Allergic, Osteonecrosis, Mental Disorder, Osteoporosis, Pain, Multiple Myeloma, Periodontitis, Overdose, Neuropathy Peripheral, Intervertebral Disc Degeneration, Depression, Injury, Gastrooesophageal Reflux Disease, Pain in JAW, Dyspnoea, Spondylolysis, Spondylolisthesis, Hepatitis Acute, Musculoskeletal Pain, Febrile Neutropenia, Osteolysis, Cognitive Disorder, Deformity, Amnesia, Osteoarthritis, Anxiety, Osteonecrosis of JAW, Heart Rate Increased, Infection

Drug(s) suspected as cause:
Aredia

Thalidomide
    Dosage: 50 mg, qd

Vincristine

Zometa
    Dosage: 4 mg, qmo

Other drugs received by patient: Clonazepam; Dexamethasone; Oxycontin; Tegretol; Neurontin



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Russian Federation on 2012-07-31

Patient:

Reactions: Vomiting, Acute Leukaemia, Febrile Neutropenia, Treatment Failure, Neutropenia, Toxicity To Various Agents, Neoplasm, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Chemoradiation
    Indication: Hodgkin's Disease

Cyclophosphamide
    Indication: Hodgkin's Disease

Dacarbazine
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Prednisone
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Indication: Hodgkin's Disease

Vinblastine Sulfate
    Indication: Hodgkin's Disease

Vincristine
    Indication: Hodgkin's Disease



Possible Vincristine side effects in female

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-07-30

Patient: female, weighing 49.0 kg (107.8 pounds)

Reactions: Death, Febrile Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Clofarabine
    Dosage: 71 mg, qdx5
    Start date: 2010-11-25
    End date: 2010-11-29

Clofarabine
    Dosage: 71 mg, qdx5
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-11-01
    End date: 2010-11-05

Oncaspar
    Dosage: 3206.3 iu, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-11-01
    End date: 2010-11-01

Oncaspar
    Dosage: 3375 iu, unk
    Start date: 2010-11-25
    End date: 2010-11-25

Vincristine
    Dosage: 2 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-11-25
    End date: 2010-11-25

Other drugs received by patient: Itraconazole; Valaciclovir



Possible Vincristine side effects in male

Reported by a physician from United States on 2012-07-27

Patient: male

Reactions: Tinnitus, Femur Fracture, Oral Cavity Fistula, Osteomyelitis, Erectile Dysfunction, Neurotoxicity, Hypoaesthesia Oral, Carpal Tunnel Syndrome, Radiculopathy, Intervertebral Disc Protrusion, Cellulitis, Gingival Bleeding, Pneumonia, Anaemia, Encephalopathy, Otitis Externa, Abscess JAW, Nasal Septum Deviation, Paraesthesia, Rhinitis Allergic, Osteosclerosis, Osteonecrosis, Mental Disorder, Osteoporosis, Pain, Multiple Myeloma, Periodontitis, Neuropathy Peripheral, Overdose, Intervertebral Disc Degeneration, Injury, Depression, Gastrooesophageal Reflux Disease, Pain in JAW, Spondylolysis, Hepatitis Acute, Spondylolisthesis, Febrile Neutropenia, Osteolysis, Cognitive Disorder, Amnesia, Deformity, Osteoarthritis, Anxiety, Osteonecrosis of JAW, Infection

Drug(s) suspected as cause:
Aredia

Thalidomide
    Dosage: 50 mg, qd

Vincristine

Zometa
    Dosage: 4 mg, qmo

Other drugs received by patient: Clonazepam; Neurontin; Oxycontin; Tegretol; Dexamethasone



Possible Vincristine side effects in

Reported by a physician from Italy on 2012-07-27

Patient:

Reactions: Anaemia, Skin Toxicity, Febrile Neutropenia, Mucosal Inflammation, Neurotoxicity, Respiratory Failure, Sepsis, Neutropenia, Cardiotoxicity, Septic Shock, Thrombocytopenia, Myocardial Infarction, Diffuse Large B-Cell Lymphoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Epirubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Mabthera
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone and Prednisone
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from Russian Federation on 2012-07-26

Patient:

Reactions: Vomiting, Acute Leukaemia, Febrile Neutropenia, Treatment Failure, Neutropenia, Toxicity To Various Agents, Neoplasm, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Chemoradiation
    Indication: Hodgkin's Disease

Cyclophosphamide
    Indication: Hodgkin's Disease

Dacarbazine
    Indication: Hodgkin's Disease

Doxorubicin Hydrochloride
    Dosage: as part of abvd or beacopp
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Prednisone
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Indication: Hodgkin's Disease

Vinblastine Sulfate
    Indication: Hodgkin's Disease

Vincristine
    Indication: Hodgkin's Disease



Possible Vincristine side effects in 1 year old male

Reported by a physician from United States on 2012-07-25

Patient: 1 year old male

Reactions: Adenovirus Infection, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Start date: 2011-05-27

Lestaurtinib
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-05-27

Mercaptopurine
    Start date: 2011-05-27

Methotrexate
    Start date: 2011-05-27

Vincristine
    Start date: 2011-05-27



Possible Vincristine side effects in female

Reported by a physician from Germany on 2012-07-24

Patient: female

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1493 mg, q2wk
    Indication: B-Cell Lymphoma
    Start date: 2012-04-26

Doxorubicin Hydrochloride
    Dosage: 100 mg, q2wk
    Indication: B-Cell Lymphoma
    Start date: 2012-04-26

Pegfilgrastim
    Dosage: unk
    Indication: B-Cell Lymphoma
    Start date: 2012-04-29

Prednisolone
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-04-26
    End date: 2012-04-30

Rituximab
    Dosage: 742.5 mg, q2wk
    Indication: B-Cell Lymphoma
    Start date: 2012-04-25

Vincristine
    Dosage: 3.54 mg, q2wk
    Indication: B-Cell Lymphoma
    Start date: 2012-04-26

Other drugs received by patient: Ramipril; Trimethoprim; Levothyroxine / 00068002 /; Simvastatin; Enoxaparin Sodium; Acetylsalicylic Acid SRT; Acyclovir; Pantoprazole; Nebivolol; Torsemide; Tiotropium Bromide



Possible Vincristine side effects in female

Reported by a consumer/non-health professional from United Kingdom on 2012-07-23

Patient: female, weighing 67.0 kg (147.4 pounds)

Reactions: Small Intestinal Obstruction, Anaemia, Febrile Neutropenia, Device Related Infection

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Start date: 2012-04-26

Doxorubicin HCL
    Start date: 2012-04-26

Prednisolone
    Administration route: Oral
    Start date: 2012-04-26

Vincristine
    Start date: 2012-04-26



Possible Vincristine side effects in

Reported by a physician from Italy on 2012-07-20

Patient:

Reactions: Anaemia, Febrile Neutropenia, Toxicity To Various Agents, Diffuse Large B-Cell Lymphoma Recurrent, Mucosal Inflammation, Neurotoxicity, Sepsis, Adverse Event, Cardiotoxicity, Neutropenia, Thrombocytopenia, Diffuse Large B-Cell Lymphoma, Lymphoma, Septic Shock

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 750 mg/m2 on day 1 for chop and 750 mg/m2 on day 2 for r-chop
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: 50 mg/m2 on day 1 for chop and 50 mg/m2 on day 2 for r-chop
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Dosage: 100 mg on days 1-5 for chop and r-chop
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: 375 mg/m2 on day 1 for r-chop
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: 1.4 mg/m2 on day 1 for chop and 1.4 mg/m2 on day 2 for r-chop upto a maximum dose of 2 mg
    Indication: Diffuse Large B-Cell Lymphoma

Other drugs received by patient: Neupogen



Possible Vincristine side effects in male

Reported by a lawyer from United States on 2012-07-20

Patient: male

Reactions: Femur Fracture, Tinnitus, Osteomyelitis, Oral Cavity Fistula, Erectile Dysfunction, Neurotoxicity, Hypoaesthesia Oral, Intervertebral Disc Protrusion, Cellulitis, Pneumonia, Anaemia, Otitis Externa, Abscess JAW, Nasal Septum Deviation, Paraesthesia, Osteonecrosis, Rhinitis Allergic, Mental Disorder, Pain, Multiple Myeloma, Periodontitis, Overdose, Neuropathy Peripheral, Intervertebral Disc Degeneration, Injury, Depression, Gastrooesophageal Reflux Disease, Pain in JAW, Spondylolysis, Spondylolisthesis, Hepatitis Acute, Febrile Neutropenia, Osteolysis, Deformity, Amnesia, Osteoarthritis, Osteonecrosis of JAW, Infection

Drug(s) suspected as cause:
Aredia

Thalidomide
    Dosage: 50 mg, qd

Vincristine

Zometa
    Dosage: 4 mg, qmo

Other drugs received by patient: Neurontin; Clonazepam; Oxycontin; Dexamethasone; Tegretol



Possible Vincristine side effects in 32 year old female

Reported by a physician from Belgium on 2012-07-19

Patient: 32 year old female, weighing 60.0 kg (132.0 pounds)

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1215 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-28

Doxorubicin HCL
    Dosage: 81 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-28
    End date: 2011-12-28

Neupogen
    Dosage: 6 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-29
    End date: 2011-12-29

Prednisone
    Dosage: 500 mg, unk
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-28

Rituximab
    Dosage: 608 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-28
    End date: 2011-12-28

Vincristine
    Dosage: 2 mg, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2011-12-28
    End date: 2011-12-28



Possible Vincristine side effects in female

Reported by a physician from United Kingdom on 2012-07-18

Patient: female, weighing 13.1 kg (28.8 pounds)

Reactions: Mucosal Inflammation, Candida Test Positive, Febrile Neutropenia, Epistaxis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: frequency: day 1, last dose prior to sae: 20/jun/2012
    Indication: Sarcoma Metastatic

Cyclophosphamide
    Dosage: last dose prior to sae 23/jun/2012
    Administration route: Oral
    Indication: Rhabdomyosarcoma
    Start date: 2012-03-01

Dactinomycin
    Dosage: frequency: day 1 of cycle dosage: 1.5 mg/m2 last dose prior to sae was taken on 30 aug 2011
    Indication: Sarcoma Metastatic

Dactinomycin
    Dosage: date of last dose prior to onset of sae: 11 oct 2011

Dactinomycin
    Dosage: dosage: 1-5 mg/m2, day 1, date of last dose prior to sae: 23 nov 2011
    Start date: 2011-07-12

Doxorubicin Hydrochloride
    Dosage: frequency: days 1 and 2 dosage: 30 mg/m2 last dose prior to sae was taken on 31 aug 2011
    Indication: Sarcoma Metastatic

Ifosfamide
    Dosage: frequency: days 1 and 2. dosage form:3g/m2 last dose prior to sae was taken on 24 nov 2011
    Indication: Sarcoma Metastatic

Mesna
    Dosage: frequency: days 1 and 2 dosage form: 3600 mg/m2 last dose prior to sae was taken on 31 aug 2011
    Indication: Sarcoma Metastatic

Mesna
    Dosage: date of last dose prior to sae: 21 sep 2011

Mesna
    Dosage: frequency: od, dosage form: 3600 mg/m2

Vincristine
    Dosage: dosage cumm: 1.5 mg/m2, frequency days 1,8 and 15 of cyclelast doseprior to sae: 23 nov 2011
    Indication: Sarcoma Metastatic

Vinorelbine Tartrate
    Dosage: last dose prior to sae:20/jun/2012
    Indication: Rhabdomyosarcoma
    Start date: 2012-03-01

Other drugs received by patient: Ondansetron; Levomepromazine; Moviprep; Fluconazole; Levomepromazine; Cotrim; Docusate; Ondansetron; Gentamicin; Morphine; Moviprep; Neupogen; Neupogen; Dihydrocodeine Bitartrate INJ; Acetaminophen; Ondansetron; Docusate; Docusate; Piperacillin and Tazobactam; Moviprep; Emollient Cream (Unk Ingredients); Ondansetron



Possible Vincristine side effects in female

Reported by a physician from France on 2012-07-18

Patient: female, weighing 40.0 kg (88.0 pounds)

Reactions: Pneumonia, General Physical Health Deterioration, Febrile Neutropenia, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-13

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-13

Istodax
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-12

Prednisone
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-13

Vincristine
    Indication: non-Hodgkin's Lymphoma
    Start date: 2011-10-27
    End date: 2012-04-13



Possible Vincristine side effects in 83 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-17

Patient: 83 year old female, weighing 50.0 kg (110.0 pounds)

Reactions: Pneumocystis Jiroveci Pneumonia, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 400 mg/m2, cyclic, on day 1 of each cycle
    Start date: 2010-10-15

Cyclophosphamide
    Dosage: 400 mg/m2, single (cycle 5)
    Start date: 2011-01-13

Doxorubicin HCL
    Dosage: 25 mg/m2, cyclic, on day 1 of each cycle
    Start date: 2010-10-15

Doxorubicin HCL
    Dosage: 25 mg/m2, single (cycle 5)
    Start date: 2011-01-13

Mabthera
    Dosage: 375 mg/m2, single (cycle 5)
    Start date: 2011-01-13

Mabthera
    Dosage: 375 mg/m2, cyclic, one day 1 of each cycle
    Start date: 2010-10-15

Prednisone
    Dosage: 40 mg/m2, cyclic, from day 1 to day 4 of each cycle
    Administration route: Oral
    Start date: 2010-10-15

Prednisone
    Dosage: 40 mg/m2, 1x/day (cycle 5)
    Administration route: Oral
    Start date: 2011-01-13
    End date: 2011-01-17

Vincristine
    Dosage: 1 mg/m2, cyclic, on day 1 of each cycle
    Start date: 2010-10-15

Vincristine
    Dosage: 1 mg/m2, single (cycle 5)
    Start date: 2011-01-13

Other drugs received by patient: Nexium



Possible Vincristine side effects in

Reported by a physician from United States on 2012-07-16

Patient:

Reactions: Fatigue, Febrile Neutropenia, Peripheral Motor Neuropathy, Peripheral Sensory Neuropathy, Arrhythmia, Cerebral Haemorrhage

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma

Etoposide
    Indication: Diffuse Large B-Cell Lymphoma

Mabthera
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Vincristine side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-13

Patient:

Reactions: Bacteraemia, Febrile Neutropenia, Haematotoxicity

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Cytarabine
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Dexamethasone
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Doxorubicin Hydrochloride
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Mabthera
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Methotrexate
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive

Vincristine
    Indication: non-Hodgkin's Lymphoma Unspecified Histology Aggressive



Possible Vincristine side effects in 61 year old male

Reported by a consumer/non-health professional from Germany on 2012-07-13

Patient: 61 year old male

Reactions: Candida Pneumonia, Bronchopneumonia, Febrile Neutropenia, Respiratory Distress, Organising Pneumonia, Respiratory Failure, Interstitial Lung Disease, Pseudomonal Sepsis, Opportunistic Infection, Stenotrophomonas Sepsis, Tracheitis, Septic Shock, Sinusitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Campath
    Dosage: 30 mg, qd
    Indication: T-Cell Lymphoma
    Start date: 2010-01-07
    End date: 2010-01-08

Campath
    Dosage: 30 mg, qd
    Start date: 2010-02-22
    End date: 2010-02-23

Cyclophosphamide
    Dosage: 1380 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2010-01-07
    End date: 2010-01-07

Cyclophosphamide
    Dosage: 690 mg, unk
    Start date: 2010-02-22
    End date: 2010-02-22

Doxorubicin HCL
    Dosage: 92 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2010-01-07
    End date: 2010-01-07

Doxorubicin HCL
    Dosage: 46 mg, unk
    Start date: 2010-02-22
    End date: 2010-02-22

Pegfilgrastim
    Dosage: 6 mg, qd
    Start date: 2010-03-01
    End date: 2010-03-01

Pegfilgrastim
    Dosage: 3 mg, qd
    Indication: T-Cell Lymphoma

Posaconazole
    Indication: Prophylaxis

Prednisone
    Dosage: 100 mg, unk
    Administration route: Oral
    Start date: 2010-02-22
    End date: 2010-02-26

Prednisone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: T-Cell Lymphoma
    Start date: 2010-01-07
    End date: 2010-01-11

Vincristine
    Dosage: 2 mg, unk
    Start date: 2010-02-22
    End date: 2010-02-22

Vincristine
    Dosage: 2 mg, unk
    Indication: T-Cell Lymphoma
    Start date: 2010-01-07
    End date: 2010-01-07



Possible Vincristine side effects in

Reported by a individual with unspecified qualification from Croatia (Local Name: Hrvatska) on 2012-07-13

Patient:

Reactions: Mucosal Inflammation, Multi-Organ Failure, Tumour Lysis Syndrome, Febrile Neutropenia, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Burkitt's Lymphoma

Cytarabine
    Indication: Burkitt's Lymphoma

Dexamethasone
    Indication: Burkitt's Lymphoma

Doxorubicin Hydrochloride
    Indication: Burkitt's Lymphoma

Etoposide
    Indication: Burkitt's Lymphoma

Ifosfamide
    Indication: Burkitt's Lymphoma

Mabthera
    Indication: Burkitt's Lymphoma

Methotrexate
    Indication: Burkitt's Lymphoma

Methylprednisolone
    Indication: Prophylaxis

Prednisone
    Indication: Burkitt's Lymphoma

Vincristine
    Indication: Burkitt's Lymphoma



Possible Vincristine side effects in female

Reported by a physician from Malaysia on 2012-07-11

Patient: female, weighing 66.8 kg (147.0 pounds)

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Blinded Gp2013
    Dosage: code not broken
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17

Blinded Mabthera
    Dosage: code not broken
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17

Blinded NO Treatment Received
    Dosage: code not broken
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17

Cyclophosphamide
    Dosage: 125 mg, qd
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17

Prednisolone
    Dosage: 100 mg, qd
    Administration route: Oral
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17

Vincristine
    Dosage: 2 mg, qd
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17

Other drugs received by patient: Allopurinol



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