Vidaza (Azacitidine Subcutaneous) - Death - Suspected Cause - Side Effect Reports

Possible Vidaza side effects in 72 year old male

Reported by a physician from Japan on 2012-08-27

Patient: 72 year old male, weighing 61.0 kg (134.2 pounds)

Reactions: Acute Myeloid Leukaemia

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2011-07-11
    End date: 2011-07-17

Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2011-08-08
    End date: 2011-08-14

Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2011-09-20
    End date: 2011-09-26

Other drugs received by patient: Almarl; Kytril; Alinamin-F; Fluconazole; Armodafinil; Norvasc; Ciprofloxacin HCL; Dexamethasone Sodium Phosphate; Neophagen; Mohrus Tape L; Dexamethasone Sodium Phosphate; Cifroquinon; Amlodipine; Heparin NA Lock; Neophagen; Norvasc; Kytril; Neophagen

Possible Vidaza side effects in female

Reported by a physician from United States on 2012-08-27

Patient: female

Reactions: Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Revlimid
    Dosage: 50 milligram
    Administration route: Oral
    Start date: 2011-07-13
    End date: 2011-01-01

Revlimid
    Dosage: 5 milligram
    Administration route: Oral
    Start date: 2011-12-01
    End date: 2012-03-23

Revlimid
    Dosage: 10 milligram
    Administration route: Oral
    Start date: 2011-09-01
    End date: 2011-12-01

Vidaza
    End date: 2012-03-01

Possible Vidaza side effects in male

Reported by a physician from Australia on 2012-08-27

Patient: male

Reactions: Pneumonia, Stevens-Johnson Syndrome, Pneumonitis

Adverse event resulted in: death, life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Bactrim
    Indication: Pneumonia

Minocycline HCL
    Dosage: 4 tablet
    Administration route: Oral
    Start date: 2009-10-12
    End date: 2010-01-07

Thalidomide
    Administration route: Oral
    Start date: 2008-09-03
    End date: 2009-08-05

Vidaza
    Start date: 2010-02-02
    End date: 2010-02-08

Vidaza
    Dosage: 75 milligram/sq. meter
    Indication: Myelodysplastic Syndrome
    Start date: 2010-01-05
    End date: 2010-01-11

Other drugs received by patient: Whole Blood; Augmentin DUO Forte

Possible Vidaza side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24

Patient: female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Other drugs received by patient: Aranesp; Granisetron; Neupogen

Possible Vidaza side effects in 36 year old male

Reported by a physician from United States on 2012-08-24

Patient: 36 year old male

Reactions: Pneumonia, Acute Myeloid Leukaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Midostaurin
    Dosage: 50 milligram
    Administration route: Oral
    Start date: 2012-02-21
    End date: 2012-02-22

Vidaza
    Dosage: 142 milligram
    Start date: 2012-02-14
    End date: 2012-02-20

Other drugs received by patient: Valtrex; Tessalon; Entocort EC; Voriconazole; Hydrea; Ativan; Phenergan HCL; Hydrocodone Bitartrate; Prograf; Claritin; Nexium; Metroprolot Tartrate; Ambien; Magnesium Oxide; Lisinopril; Dilaudid; Zofran; Magnesium Sulfate

Possible Vidaza side effects in 80 year old male

Reported by a physician from Germany on 2012-08-24

Patient: 80 year old male, weighing 75.0 kg (165.0 pounds)

Reactions: Pneumonia, Cardiac Failure, Sepsis, Pulmonary Oedema, Pancytopenia, Abscess Sweat Gland

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Vidaza
    Dosage: 145 milligram
    Start date: 2012-02-20
    End date: 2012-02-24

Vidaza
    Dosage: 145 milligram
    Start date: 2012-03-26
    End date: 2012-03-27

Vidaza
    Dosage: 145 milligram
    Start date: 2012-02-27
    End date: 2012-02-28

Vidaza
    Dosage: 145 milligram
    Start date: 2012-03-19
    End date: 2012-03-23

Other drugs received by patient: Esidrix; Flutrimazole; Ramipril; Lorazepam; Xylocaine; Prednisolone; Pantoprazole; Polyethylene Glycol; Sodium Chloride; Ondansetron; Carvedilol; Ondansetron; Torsemide

Possible Vidaza side effects in

Reported by a physician from Switzerland on 2012-08-23

Patient:

Reactions: Death, Acute Myeloid Leukaemia

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Possible Vidaza side effects in 78 year old male

Reported by a physician from Germany on 2012-08-23

Patient: 78 year old male, weighing 115.0 kg (253.0 pounds)

Reactions: Pneumonia, Febrile Neutropenia, Bronchitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Vidaza

Other drugs received by patient: Deferasirox; Amiodarone HCL; Imipra; Lenograstim; Formoterol Fumarate; Pregabalin; Fentanyl; Platelets; Bisoprolol Fumarate; Pantoprazole; Transfusion

Possible Vidaza side effects in 63 year old male

Reported by a physician from Australia on 2012-08-23

Patient: 63 year old male

Reactions: Aortitis, Blast Crisis in Myelogenous Leukaemia, Coronary Artery Stenosis, Pancytopenia, Febrile Neutropenia, Rash, Constipation, Cardiac Failure, Joint Swelling, Disease Recurrence, Pseudomonal Sepsis, Neutropenia, Arteritis Coronary

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Thalidomide
    Dosage: 100 milligram
    Administration route: Oral

Vidaza
    Dosage: 50% dose reduction

Vidaza
    Dosage: 75 milligram/sq. meter

Other drugs received by patient: Cytarabine; Fludarabine Phosphate

Possible Vidaza side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-22

Patient: female, weighing 66.3 kg (145.9 pounds)

Reactions: Weight Decreased, Vomiting, Gout, Nausea, Acute Myeloid Leukaemia, NO Therapeutic Response, Cerebral Haemorrhage

Adverse event resulted in: death, hospitalization, disablity

Drug(s) suspected as cause:
Vidaza
    Dosage: 130 milligram
    Start date: 2012-02-13
    End date: 2012-02-17

Vidaza
    Dosage: 130 milligram
    Indication: Myelodysplastic Syndrome
    Start date: 2012-01-16
    End date: 2012-01-24

Other drugs received by patient: Allopurinol; Tranexamic Acid; Domperidone; Granisetron

Possible Vidaza side effects in male

Reported by a physician from Japan on 2012-08-21

Patient: male, weighing 57.0 kg (125.4 pounds)

Reactions: Blast Cell Count Increased, Sepsis, Anaemia, Platelet Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Vidaza
    Dosage: 75 milligram/sq. meter
    Indication: Myelodysplastic Syndrome
    Start date: 2011-05-16
    End date: 2011-05-22

Vidaza
    Dosage: 25 milligram/sq. meter
    Start date: 2011-08-25
    End date: 2011-08-29

Vidaza
    Dosage: 25 milligram/sq. meter
    Start date: 2011-07-05
    End date: 2011-07-09

Other drugs received by patient: Olmesartan Medoxomil; Lasix; Firstcin; Belmaton; Whole Blood; Firstcin; Serotone; Calblock; Famotidine; Fosmicin-S; Funguard; Cytarabine; Serotone; Serotone; Acrasin; Urinorm; Omegacin

Possible Vidaza side effects in

Reported by a physician from Japan on 2012-08-21

Patient: , weighing 71.0 kg (156.2 pounds)

Reactions: Pneumonia, Sepsis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Vidaza
    Dosage: 25 milligram/sq. meter
    Start date: 2011-10-31
    End date: 2011-11-04

Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2011-09-12
    End date: 2011-09-16

Other drugs received by patient: Meropenem; Doripenem Monohydrate; Zoloft; Purnoside; Platelets; Serotone; Raden; Meilax; Belmaton; Funguard; Bezatol SR; Firstcin; RED Blood Cells; Magmitt; Ledolper

Possible Vidaza side effects in 77 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-20

Patient: 77 year old female, weighing 42.0 kg (92.4 pounds)

Reactions: Haemoglobin Decreased, White Blood Cell Count Decreased, Pneumonia, RED Blood Cell Count Decreased, Platelet Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2011-07-28
    End date: 2011-08-03

Vidaza
    Dosage: 25 milligram/sq. meter
    Start date: 2012-06-12
    End date: 2012-06-18

Vidaza
    Dosage: 25 milligram/sq. meter
    Start date: 2012-02-20
    End date: 2012-02-26

Vidaza
    Dosage: 25 milligram/sq. meter
    Start date: 2011-12-17
    End date: 2011-12-23

Vidaza
    Dosage: 25 milligram/sq. meter
    Start date: 2011-11-03
    End date: 2011-11-09

Other drugs received by patient: Itraconazole; Olopatadine HCL; Bactrim; Gascon; Morphine Hydrochloride Hydrate; Ticlopidine HCL; Gasmotin; Maglax; Aspirin; Gasmotin; Vfend; Hanp; Vfend; Lansoprazole; Polymyxin B Sulfate; Vfend; Serotone; Firstcin; Levofloxacin; Serotone

Possible Vidaza side effects in male

Reported by a physician from Switzerland on 2012-08-20

Patient: male

Reactions: Acute Myeloid Leukaemia

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Possible Vidaza side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-20

Patient:

Reactions: Pneumonia, Gastrointestinal Disorder, Sepsis, Cardiac Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Possible Vidaza side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20

Patient: female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Other drugs received by patient: Ondansetron

Possible Vidaza side effects in

Reported by a physician from Italy on 2012-08-17

Patient:

Reactions: Pneumonia, Acute Myeloid Leukaemia, Anaemia, Recurrent Cancer, Constipation, Injection Site Erythema, Sepsis, Neutropenia, Thrombocytopenia, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza
    Dosage: 100 milligram
    Start date: 2005-10-01
    End date: 2011-08-01

Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2005-10-01
    End date: 2011-08-01

Possible Vidaza side effects in 80 year old male

Reported by a physician from Germany on 2012-08-17

Patient: 80 year old male, weighing 75.0 kg (165.0 pounds)

Reactions: Pneumonia, Cardiac Failure, Sepsis, Pulmonary Oedema, Pancytopenia, Abscess Sweat Gland

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Vidaza
    Dosage: 145 milligram
    Start date: 2012-02-20
    End date: 2012-02-28

Vidaza
    Dosage: 145 milligram
    Start date: 2012-03-19
    End date: 2012-03-27

Other drugs received by patient: Vancomycin; Meropenem; Armodafinil; Diuretics; Nitrate; Morphine

Possible Vidaza side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-15

Patient: male, weighing 91.7 kg (201.7 pounds)

Reactions: Pneumonia, Anaemia, Pancytopenia, Febrile Neutropenia, Respiratory Failure, Muscle Abscess, Thrombocytopenia, Cardiac Arrest

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Rituxan
    Dosage: 150 milligram
    Start date: 2012-05-14

Rituxan
    Start date: 2012-06-22

Rituxan
    Start date: 2012-07-19
    End date: 2012-07-20

Rituxan
    Dosage: 17.8571 milligram
    Start date: 2012-08-04

Vidaza
    Dosage: 150 milligram
    Start date: 2012-05-14

Vidaza
    Dosage: 150 milligram
    Start date: 2012-07-19
    End date: 2012-07-20

Other drugs received by patient: Procrit; Fluticasone Propionate; Folic Acid; Hydrocortisone-Pramoxine; Metoprolol Tartrate; Rosuvastatin; Meropenem; Vancomycin; Dextrose; Acetaminophen; Calcium + Vitamin D; Ciprofloxacin-Dexamethasone Otic; Diphenhydramine Hydrochloride; Filgrastim; Multi-Vitamins; Phenylephrine Hydrochloride; Acetaminophen; Naproxen; Whole Blood; Prednisone TAB; Vitamin B-12; Acetaminophen; Benazepril Hydrochloride; Augmentin '500'; Amlodipine; Omeprazole; Sodium Chloride

Possible Vidaza side effects in male

Reported by a physician from United States on 2012-08-15

Patient: male, weighing 58.5 kg (128.7 pounds)

Reactions: Pneumonia, Hepatotoxicity, Sepsis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Midostaurin
    Dosage: 150 milligram
    Start date: 2012-07-23
    End date: 2012-07-29

Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2012-06-18
    End date: 2012-06-24

Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2012-07-16
    End date: 2012-07-22

Other drugs received by patient: Amlodipine; Ativan; Metformin Hydrochloride; Humulin R; Tylenol; Clotrimazole; Fluconazole; Ondansetron; Lantus; Levothyroxine Sodium; Humalog; Fluids; Acyclovir; Famotidine

Possible Vidaza side effects in male

Reported by a physician from Israel on 2012-08-15

Patient: male

Reactions: Myelodysplastic Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Possible Vidaza side effects in male

Reported by a physician from Australia on 2012-08-14

Patient: male

Reactions: Pneumonia, Pneumonitis, Stevens-Johnson Syndrome

Adverse event resulted in: death, life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Bactrim
    Indication: Pneumonia

Minocycline HCL
    Dosage: 4 tablet
    Administration route: Oral
    Start date: 2009-10-12
    End date: 2010-01-07

Thalidomide
    Administration route: Oral
    Start date: 2008-09-03
    End date: 2009-08-05

Vidaza
    Start date: 2010-02-02
    End date: 2010-02-08

Vidaza
    Dosage: 75 milligram/sq. meter
    Indication: Myelodysplastic Syndrome
    Start date: 2010-01-05
    End date: 2010-01-11

Other drugs received by patient: Augmentin DUO Forte; Whole Blood

Possible Vidaza side effects in 70 year old male

Reported by a physician from Israel on 2012-08-14

Patient: 70 year old male

Reactions: Viral Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Possible Vidaza side effects in 82 year old male

Reported by a physician from Germany on 2012-08-14

Patient: 82 year old male, weighing 70.0 kg (154.0 pounds)

Reactions: Acute Myeloid Leukaemia

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Other drugs received by patient: Platelets

Possible Vidaza side effects in female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-14

Patient: female, weighing 41.0 kg (90.2 pounds)

Reactions: Haemoglobin Decreased, Lymphocyte Count Increased, White Blood Cell Count Decreased, Monocyte Count Decreased, RED Blood Cell Count Decreased, Platelet Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2012-03-01
    End date: 2012-03-07

Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2012-01-05
    End date: 2012-01-11

Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2012-02-02
    End date: 2012-02-08

Vidaza
    Dosage: 75 milligram/sq. meter
    Start date: 2011-12-08
    End date: 2011-12-14

Other drugs received by patient: Coniel; Vancomycin; Magmitt; Gran; Meropenem; Ambisome; Bisoprolol Fumarate; Granisetron Hydrochloride; Gran; Solu-Cortef; Myser; Meropenem; Toracona; Ciprofloxacin HCL; Ambisome; Lasix; Lansoprazole; Meropenem

Possible Vidaza side effects in 66 year old female

Reported by a physician from Japan on 2012-08-14

Patient: 66 year old female, weighing 49.0 kg (107.8 pounds)

Reactions: Bronchopulmonary Aspergillosis, Sepsis, Platelet Count Decreased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Vidaza

Other drugs received by patient: Laxoberon; Kativ-N; Folic Acid; Polaramine; Antibiotics; Alosenn; Lasix; Pyrinazin; Vancomycin; NEO-Minophagen C; Levofloxacin; Sodium Bicarbonate; Meropenem; Diflucan; Maglax; Valtrex

Possible Vidaza side effects in 73 year old female

Reported by a physician from Israel on 2012-08-14

Patient: 73 year old female

Reactions: Leukaemia

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Possible Vidaza side effects in 74 year old male

Reported by a physician from Japan on 2012-08-14

Patient: 74 year old male, weighing 62.0 kg (136.4 pounds)

Reactions: Pneumonia

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza

Other drugs received by patient: Verapamil HCL; Allopurinol; Cefepime; Meropenem; Pradaxa

Possible Vidaza side effects in male

Reported by a physician from Japan on 2012-08-13

Patient: male, weighing 62.0 kg (136.4 pounds)

Reactions: Malaise, Hypoproteinaemia, Cardiac Failure, Hepatic Congestion, Cystitis

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Vidaza

Other drugs received by patient: Elneopa No.1; Elneopa No.2; Aspara; Dexamethasone Sodium Phosphate; Sulfamethoxazole and Trimethoprim; TPN Electrolytes IN Plastic Container; Carvedilol; Digoxin; Prednisolone; Exjade; Nateglinide; Warfarin Sodium; Lasix; Potassium

Possible Vidaza side effects in

Reported by a individual with unspecified qualification from Austria on 2012-08-13

Patient:

Reactions: Lung Infection, Myocardial Ischaemia, Pyrexia, Device Related Infection, Neoplasm, Cardiac Disorder, Upper Respiratory Tract Infection, Fracture, Herpes Simplex, Metabolic Disorder, Blood Pressure Abnormal, Anaemia, Gastrointestinal Disorder, NO Therapeutic Response, Nervous System Disorder, Neutropenia, Abscess, Haemorrhage, Pain, Left Ventricular Failure, Constipation, Liver Disorder, Disease Progression, Death, Fatigue, Injection Site Reaction, Thrombocytopenia, Renal Disorder, Vomiting, Nausea, Urinary Tract Infection, Acute Myeloid Leukaemia, Febrile Neutropenia, Arrhythmia, Gastrointestinal Infection, Embolism, Diarrhoea, Sepsis, Cytomegalovirus Infection, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Vidaza
    Start date: 2007-02-01
    End date: 2012-02-01

Vidaza
    Start date: 2007-02-01
    End date: 2011-07-01

Other drugs received by patient: Erythropoiesis Stimulating Agents; Integrative Cancer Treatment; Neupogen