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Velcade (Bortezomib) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (290)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Velcade (Bortezomib) life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 290   Next >>

Possible Velcade side effects in male

Reported by a physician from Germany on 2012-08-24

Patient: male

Reactions: Portal Hypertension, Pain, Thrombocytopenia, Epistaxis, Decreased Appetite, Renal Failure Acute, Bronchopulmonary Aspergillosis, Pseudomonas Infection, Anaemia, Hyperviscosity Syndrome, Rash, Haemangioma of Spleen, Pulmonary Sepsis, Syncope, Respiratory Failure, Visual Impairment, Leukopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cotrim DS
    Indication: Product Used FOR Unknown Indication

Dexamethasone Sodium Phosphate
    Indication: Multiple Myeloma
    Start date: 2012-03-21
    End date: 2012-04-01

Dexamethasone Sodium Phosphate
    Start date: 2012-03-01
    End date: 2012-03-12

Dexamethasone Sodium Phosphate
    Start date: 2012-05-21
    End date: 2012-06-10

Dexamethasone Sodium Phosphate
    Start date: 2012-04-17
    End date: 2012-04-28

Doxorubicin HCL
    Indication: Multiple Myeloma
    Start date: 2012-03-21
    End date: 2012-04-01

Doxorubicin HCL
    Start date: 2012-04-17
    End date: 2012-04-28

Lenalidomide
    Indication: Multiple Myeloma
    Start date: 2012-05-21
    End date: 2012-06-10

Velcade
    Indication: Multiple Myeloma
    Start date: 2012-04-17
    End date: 2012-04-28

Velcade
    Start date: 2012-03-21
    End date: 2012-04-01

Velcade
    Start date: 2012-03-01
    End date: 2012-03-12

Other drugs received by patient: Acyclovir



Possible Velcade side effects in

Reported by a physician from France on 2012-08-23

Patient:

Reactions: Back Pain, Electrocardiogram QT Prolonged, Dyspnoea, Hypotension, Thrombocytopenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 20 mg, unk
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-22
    End date: 2012-05-29

JNJ-26481585
    Dosage: 12 mg, unk
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-21
    End date: 2012-05-31

Velcade
    Dosage: 2.1 mg, unk
    Indication: Multiple Myeloma
    Start date: 2012-05-22
    End date: 2012-05-29

Other drugs received by patient: Ceftriaxone; Primperan / 00041901 /; Acetaminophen; Zelitrex / 01269701 /; Fentanyl; Atracurium Besylate; Kardegic / 00002703 /; Oxycontin; Oxygen; Tranxene; Primperan / 00041901 /; Bumetanide; Crestor; Primperan / 00041901 /; Hydrocortisone; Ondansetron; Ondansetron; Ondansetron; Importal; Tramadol HCL; Noradrenaline / 00127501 /; Tramadol HCL; Morphine; Furosemide; Midazolam; Tramadol HCL



Possible Velcade side effects in female

Reported by a physician from Japan on 2012-08-22

Patient: female, weighing 51.0 kg (112.2 pounds)

Reactions: Cheyne-Stokes Respiration, Cardiac Failure, Pain, Depressed Level of Consciousness, Platelet Count Decreased, Cardiac Amyloidosis, Liver Disorder

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Fentanyl-100
    Indication: Cancer Pain
    Start date: 2012-04-25
    End date: 2012-04-25

Velcade
    Start date: 2012-03-26

Velcade
    Start date: 2012-03-19

Velcade
    Indication: Multiple Myeloma
    End date: 2012-04-19

Velcade
    Indication: Renal Amyloidosis
    Start date: 2012-03-23

Velcade
    End date: 2012-04-19

Velcade
    Start date: 2012-03-19

Velcade
    End date: 2012-04-12

Velcade
    Start date: 2012-03-23

Velcade
    Start date: 2012-03-26

Velcade
    End date: 2012-04-12

Velcade
    Start date: 2012-03-26

Velcade
    Start date: 2012-03-16

Velcade
    Start date: 2012-03-23

Velcade
    End date: 2012-04-16

Velcade
    End date: 2012-04-12

Velcade
    End date: 2012-04-09

Velcade
    Start date: 2012-03-16

Velcade
    End date: 2012-04-09

Velcade
    Start date: 2012-03-19

Velcade
    End date: 2012-04-09

Velcade
    End date: 2012-04-16

Velcade
    Indication: Cardiac Amyloidosis
    End date: 2012-04-19

Velcade
    End date: 2012-04-16

Velcade
    Start date: 2012-03-16

Other drugs received by patient: Zyvox; Dopamine HCL; Carvedilol; Tolvaptan; Losartan Potassium; Amiodarone HCL; Dexamethasone Acetate; Lasix; Albumin (Human); Lasix; Azosemide; Forsenid; Trichlormethiazide; Valtrex; Fentanyl Citrate; Azosemide; Eplerenone; AN Unknown Medication; Losartan Potassium; Omeprazole



Possible Velcade side effects in

Reported by a consumer/non-health professional from Singapore on 2012-08-22

Patient:

Reactions: Incorrect Route of Drug Administration, Myalgia, Tumour Lysis Syndrome, Rhabdomyolysis, Demyelination

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Etoposide
    Dosage: unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Ifosfamide
    Dosage: unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Rituximab
    Dosage: unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Velcade
    Dosage: unk mg/m2, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Velcade
    Dosage: unk
    Start date: 2012-07-31

Other drugs received by patient: Methotrexate; Lamivudine; Acyclovir; Pentamidine; Omeprazole



Possible Velcade side effects in 59 year old female

Reported by a physician from United States on 2012-08-22

Patient: 59 year old female, weighing 67.8 kg (149.1 pounds)

Reactions: Embolism, Muscular Weakness, Gastric Haemorrhage, Cardiac Arrest

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 40 mg, cyclic
    Administration route: Oral
    Indication: Amyloidosis
    Start date: 2012-07-09
    End date: 2012-08-09

Melphalan Hydrochloride
    Dosage: 0.22 mg/kg, cyclic
    Administration route: Oral
    Indication: Amyloidosis
    Start date: 2012-07-09
    End date: 2012-08-09

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Amyloidosis
    Start date: 2012-07-09
    End date: 2012-08-09

Velcade
    Dosage: 1.3 mg/m2, cyclic



Possible Velcade side effects in

Reported by a physician from Germany on 2012-08-22

Patient:

Reactions: Hypertensive Crisis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Velcade

Other drugs received by patient: Melphalan Hydrochloride; Prednisolone; Acyclovir; Zometa



Possible Velcade side effects in

Reported by a physician from Turkey on 2012-08-21

Patient:

Reactions: Asthma, Pneumonia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Velcade
    Dosage: unk
    Indication: Multiple Myeloma
    Start date: 2011-12-22
    End date: 2012-03-12

Velcade
    Dosage: unk
    Start date: 2012-03-22

Other drugs received by patient: Tiotropium Bromide; Clarithromycin; Moxifloxacin; Tazobactam; Dexamethasone; Zometa; Ceftriaxone Sodium; Formoterol Fumarate; Methylprednisolone; Dexamethasone



Possible Velcade side effects in

Reported by a physician from Greece on 2012-08-21

Patient:

Reactions: Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Velcade



Possible Velcade side effects in

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-08-20

Patient:

Reactions: Thrombotic Thrombocytopenic Purpura

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Bendamustine Hydrochloride
    Dosage: 90 mg/m2, unk
    Indication: Mantle Cell Lymphoma

Velcade
    Dosage: 1.3 mg/m2, unk
    Indication: Mantle Cell Lymphoma

Other drugs received by patient: Rituximab



Possible Velcade side effects in

Reported by a physician from United States on 2012-08-20

Patient:

Reactions: Multi-Organ Failure, Sepsis, Cerebral Ischaemia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia

PEG-Asparaginase
    Indication: Acute Lymphocytic Leukaemia

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Velcade side effects in

Reported by a physician from Italy on 2012-08-20

Patient:

Reactions: Dyspnoea, Anaemia, Pancytopenia, Thrombocytopenia, Asthenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Velcade

Other drugs received by patient: Nitroglycerin; Bisoprolol Fumarate; Dexamethasone; Furosemide; Lasix; Dexamethasone



Possible Velcade side effects in

Reported by a physician from Turkey on 2012-08-20

Patient:

Reactions: Pneumonia, Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 20 mg, unk
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2009-02-09
    End date: 2009-04-20

Velcade
    Dosage: 2.57 mg, unk
    Indication: Multiple Myeloma
    Start date: 2009-02-09
    End date: 2009-04-20



Possible Velcade side effects in

Reported by a physician from United States on 2012-08-20

Patient:

Reactions: Multi-Organ Failure, Sepsis, Hypoxia, Pleural Effusion

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia

PEG-Asparaginase
    Indication: Acute Lymphocytic Leukaemia

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Velcade side effects in

Reported by a physician from Germany on 2012-08-20

Patient:

Reactions: Infection

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: unk
    Indication: Multiple Myeloma
    Start date: 2012-03-26
    End date: 2012-07-05

Dexamethasone
    Dosage: unk
    Indication: Multiple Myeloma
    Start date: 2012-03-26
    End date: 2012-07-05

Velcade
    Dosage: unk
    Indication: Multiple Myeloma
    Start date: 2012-03-26
    End date: 2012-07-05

Other drugs received by patient: Zometa; Amoxicillin



Possible Velcade side effects in female

Reported by a physician from United States on 2012-08-20

Patient: female, weighing 70.8 kg (155.8 pounds)

Reactions: Abdominal Pain, Hyperpyrexia, Anaphylactic Reaction, Chills, Pain, Hepatic Failure, Transaminases Increased, Splenic Infarction, Loss of Consciousness, Aortic Thrombosis, Off Label Use, Malaise, C-Reactive Protein Increased, Myositis, Dyspnoea, Hypotension, Arrhythmia, Lung Consolidation, Hypophosphataemia, Zygomycosis, Bacteraemia, Ventricular Tachycardia, Hyperammonaemia, Neutropenia, Hepatic Infarction, Shock, Infusion Related Reaction

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Cytarabine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Decadron Phosphate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Doxil
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Methotrexate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2005-01-01
    End date: 2007-01-01

PEG-Asparaginase
    Dosage: day 2, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-25
    End date: 2007-10-25

Velcade
    Dosage: day 1, 4, 8 and 11
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Vincristine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23



Possible Velcade side effects in

Reported by a physician from United States on 2012-08-20

Patient:

Reactions: Multi-Organ Failure, Sepsis, Hypoxia

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia

PEG-Asparaginase
    Indication: Acute Lymphocytic Leukaemia

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia



Possible Velcade side effects in

Reported by a physician from Turkey on 2012-08-20

Patient:

Reactions: Asthma, Pneumonia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Velcade
    Dosage: unk
    Indication: Multiple Myeloma
    Start date: 2011-12-22
    End date: 2012-03-12

Velcade
    Dosage: unk
    Start date: 2012-03-22

Other drugs received by patient: Dexamethasone; Dexamethasone; Tiotropium Bromide; Moxifloxacin; Tazobactam; Formoterol Fumarate; Zometa; Clarithromycin; Methylprednisolone; Ceftriaxone Sodium



Possible Velcade side effects in 14 year old male

Reported by a physician from United States on 2012-08-20

Patient: 14 year old male, weighing 71.4 kg (157.1 pounds)

Reactions: Dyspnoea, Hypotension, Sepsis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: 100 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-08-09
    End date: 2012-08-10

Cytarabine
    Dosage: 70 mg, cyclic
    Start date: 2012-08-09
    End date: 2012-08-09

Daunorubicin HCL
    Dosage: 50 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-08-09
    End date: 2012-08-09

Etoposide
    Dosage: 100 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-08-09
    End date: 2012-08-09

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-08-09
    End date: 2012-08-09



Possible Velcade side effects in

Reported by a physician from Japan on 2012-08-17

Patient:

Reactions: Cheyne-Stokes Respiration, Cancer Pain, Pain, Cardiac Amyloidosis, Staphylococcal Sepsis, Liver Disorder, Cardiac Failure, Platelet Count Decreased, Depressed Level of Consciousness, Septic Shock

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Fentanyl
    Dosage: 12.5 unk, unk
    Indication: Cancer Pain
    Start date: 2012-04-25
    End date: 2012-04-25

Velcade
    Dosage: 1.824 mg/m2, unk
    Indication: Multiple Myeloma
    Start date: 2012-03-16
    End date: 2012-04-12

Velcade
    Indication: Renal Amyloidosis

Velcade
    Indication: Cardiac Amyloidosis

Other drugs received by patient: Human Albumin / 01102501 /; Dexamethasone; Losartan Potassium; Furosemide; Eplerenone; Omeprazole; Zyvox; Sennoside / 00571902 /; Dopamine HCL; Pursennid / 00142207 /; Losartan Potassium; Furosemide; Amiodarone Hydrochloride; Valaciclovir; Azosemide; Daikenchuto; Carvedilol; Trichlormethiazide; Azosemide; Tolvaptan



Possible Velcade side effects in

Reported by a physician from France on 2012-08-16

Patient:

Reactions: Electrocardiogram QT Prolonged, Back Pain, Dyspnoea, Hypotension, Thrombocytopenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 20 mg, unk
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-22
    End date: 2012-05-29

JNJ-26481585
    Dosage: 12 mg, unk
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2012-05-21
    End date: 2012-05-31

Velcade
    Dosage: 2.1 mg, unk
    Indication: Multiple Myeloma
    Start date: 2012-05-22
    End date: 2012-05-29

Other drugs received by patient: Ceftriaxone; Primperan / 00041901 /; Bumetanide; Acetaminophen; Morphine; Atracurium Besylate; Ondansetron; Crestor; Fentanyl; Furosemide; Midazolam; Tranxene; Ondansetron; Tramadol HCL; Noradrenaline / 00127501 /; Hydrocortisone; Importal; Tramadol HCL; Kardegic / 00002703 /; Primperan / 00041901 /; Primperan / 00041901 /; Tramadol HCL; Zelitrex / 01269701 /; Oxycontin; Oxygen; Ondansetron



Possible Velcade side effects in 4 year old female

Reported by a consumer/non-health professional from United States on 2012-08-16

Patient: 4 year old female, weighing 13.7 kg (30.1 pounds)

Reactions: Blood Bilirubin Increased, Hyponatraemia, Hypernatraemia, Caecitis, Hypokalaemia, Hypophosphataemia, Left Ventricular Dysfunction, Cardiac Failure, Ileus, Diarrhoea, Venoocclusive Liver Disease, Hypocalcaemia, Acute Respiratory Distress Syndrome

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: unk, cyclic

Cytarabine
    Dosage: 100 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-06-20
    End date: 2012-07-05

Daunorubicin HCL
    Dosage: 50 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-06-20
    End date: 2012-06-24

Etoposide
    Dosage: 100 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-06-20
    End date: 2012-06-24

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-06-20
    End date: 2012-06-25



Possible Velcade side effects in 64 year old male

Reported by a physician from United States on 2012-08-16

Patient: 64 year old male, weighing 91.7 kg (201.7 pounds)

Reactions: Fungaemia, Blood Bilirubin Increased, Histiocytosis Haematophagic, Pyrexia, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Decitabine
    Dosage: 20 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-05-25
    End date: 2012-07-02

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-05-25
    End date: 2012-07-02

Other drugs received by patient: Lisinopril; Pantoprazole; Zolpidem Tartrate; Dilaudid; Metoprolol Tartrate; Cyclobenzaprine; Cefepime; Amlodipine; Atenolol; Oxycodone HCL; Sennosides A+B; Acetylsalicylic Acid SRT; Lactulose; Polyethylene Glycol; Nexium; Clopidogrel; Docusate Sodium; Furosemide; Lorazepam; Vardenafil Hydrochloride (Levitra); Acetaminophen; Calcium Carbonate; Ceftriaxone; Metoclopramide HCL / 00041902 /; Nitroglycerin; Famotidine; Flagyl; Rosuvastatin; Acyclovir; Simethicone; Dexamethasone; Vancomycin



Possible Velcade side effects in female

Reported by a physician from United States on 2012-08-14

Patient: female, weighing 70.8 kg (155.8 pounds)

Reactions: Abdominal Pain, Rhabdomyolysis, Hyperpyrexia, Chills, Anaphylactic Reaction, Bone Pain, Hepatic Failure, Transaminases Increased, Loss of Consciousness, Aortic Thrombosis, Splenic Infarction, Hypokalaemia, Malaise, C-Reactive Protein Increased, Dyspnoea, Hypotension, Hypophosphataemia, Zygomycosis, Bacteraemia, Hyperammonaemia, Neutropenia, Hepatic Infarction, Lung Infiltration, Shock, Infusion Related Reaction

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: 70 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2005-01-01
    End date: 2007-10-23

Decadron Phosphate
    Dosage: 9 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Doxorubicin HCL
    Dosage: 107 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Methotrexate Sodium
    Dosage: unk, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2005-01-01
    End date: 2007-01-01

Pegaspargase
    Dosage: unk, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-25

Velcade
    Dosage: 1.3 mg/m2, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Vincristine
    Dosage: 2 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23



Possible Velcade side effects in

Reported by a physician from Greece on 2012-08-13

Patient:

Reactions: Pulmonary Haemorrhage, Off Label Use, Respiratory Arrest, Cardiac Arrest, Infection

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Velcade

Other drugs received by patient: Dexamethasone; Rituximab; Baraclude; Lamivudine



Possible Velcade side effects in

Reported by a consumer/non-health professional from Singapore on 2012-08-13

Patient:

Reactions: Myalgia, Incorrect Route of Drug Administration, Rhabdomyolysis, Tumour Lysis Syndrome, Demyelination

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Etoposide
    Dosage: unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Ifosfamide
    Dosage: unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Rituximab
    Dosage: unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Velcade
    Dosage: unk mg/m2, unk
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-06-21
    End date: 2012-07-26

Velcade
    Dosage: unk
    Start date: 2012-07-31

Other drugs received by patient: Methotrexate Sodium; Acyclovir; Pentamidine; Omeprazole; Lamivudine



Possible Velcade side effects in male

Reported by a physician from United States on 2012-08-09

Patient: male, weighing 31.8 kg (70.0 pounds)

Reactions: Abdominal Pain, Atelectasis, Disseminated Intravascular Coagulation, Acidosis, Pericardial Effusion, Activated Partial Thromboplastin Time Prolonged, Multi-Organ Failure, Left Ventricular Dysfunction, Pulmonary Oedema, Mediastinal Haemorrhage, Blood Creatinine Increased, Renal Failure Acute, Dyspnoea, Angina Pectoris, Alanine Aminotransferase Increased, Hypotension, Hypercalcaemia, Respiratory Failure, Embolism, Cardiac Failure, Aspartate Aminotransferase Increased, Ventricular Tachycardia, Ejection Fraction Decreased, Hypoalbuminaemia, Ventricular Fibrillation, Sinus Tachycardia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Ativan
    Indication: Product Used FOR Unknown Indication

Cytarabine
    Dosage: 100 mg/kg, unk
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-06-01
    End date: 2012-06-11

Daunorubicin HCL
    Dosage: 50 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-06-01
    End date: 2012-06-05

Etoposide
    Dosage: 100 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-06-01
    End date: 2012-06-05

Fentanyl
    Indication: Product Used FOR Unknown Indication

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Acute Myeloid Leukaemia
    Start date: 2012-06-01
    End date: 2012-06-01



Possible Velcade side effects in 60 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-09

Patient: 60 year old female

Reactions: Myelofibrosis, Acute Myeloid Leukaemia, Myelodysplastic Syndrome, Idiopathic Thrombocytopenic Purpura

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Alkeran
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Bicnu
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Cyclophosphamide
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: 4 years, intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Doxorubicin Hydrochloride
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Prednisone
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Velcade
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma
    Start date: 2008-05-05

Velcade
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma
    Start date: 2008-05-19

Velcade
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma
    Start date: 2008-04-08

Vepesid
    Dosage: intravenous (not otherwise sepcified)
    Indication: Multiple Myeloma

Vincristine Sulfate
    Dosage: intravenous (not otherwise specified)
    Indication: Multiple Myeloma

Other drugs received by patient: Neupogen; Corticosteroids



Possible Velcade side effects in

Reported by a physician from United Kingdom on 2012-08-09

Patient:

Reactions: Small Intestinal Obstruction, Vomiting, Nausea, Abdominal Pain Upper

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1340 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Doxorubicin Hydrochloride
    Dosage: 90 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Prednisolone
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Rituximab
    Dosage: 670 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Velcade
    Dosage: 2.3 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-30
    End date: 2012-06-08

Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-05-11
    End date: 2012-05-30

Other drugs received by patient: Acyclovir; Allopurinol; Amitriptyline HCL; Omeprazole; Amitriptyline HCL; Metoclopramide; Metoclopramide



Possible Velcade side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-08

Patient: 49 year old male

Reactions: Thrombotic Thrombocytopenic Purpura

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Rituximab
    Indication: Mantle Cell Lymphoma

Treanda
    Indication: Mantle Cell Lymphoma

Velcade
    Indication: Mantle Cell Lymphoma



Possible Velcade side effects in male

Reported by a physician from Germany on 2012-08-07

Patient: male

Reactions: Portal Hypertension, Pain, Thrombocytopenia, Decreased Appetite, Renal Failure Acute, Epistaxis, Bronchopulmonary Aspergillosis, Pseudomonas Infection, Anaemia, Hyperviscosity Syndrome, Rash, Pulmonary Sepsis, Haemangioma of Spleen, Syncope, Respiratory Failure, Visual Impairment, Leukopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cotrim DS
    Indication: Product Used FOR Unknown Indication

Dexamethasone Sodium Phosphate
    Start date: 2012-05-21
    End date: 2012-06-10

Dexamethasone Sodium Phosphate
    Indication: Multiple Myeloma
    Start date: 2012-04-17
    End date: 2012-04-28

Dexamethasone Sodium Phosphate
    Start date: 2012-03-01
    End date: 2012-03-12

Dexamethasone Sodium Phosphate
    Start date: 2012-03-21
    End date: 2012-04-01

Doxorubicin HCL
    Indication: Multiple Myeloma
    Start date: 2012-04-17
    End date: 2012-04-28

Doxorubicin HCL
    Start date: 2012-03-21
    End date: 2012-04-01

Lenalidomide
    Indication: Multiple Myeloma
    Start date: 2012-05-21
    End date: 2012-06-10

Velcade
    Indication: Multiple Myeloma
    Start date: 2012-03-01
    End date: 2012-03-12

Velcade
    Start date: 2012-04-17
    End date: 2012-04-28

Velcade
    Start date: 2012-03-21
    End date: 2012-04-01

Other drugs received by patient: Acyclovir



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