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Vectibix (Panitumumab) - Diarrhoea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Diarrhoea (8)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Vectibix (Panitumumab) where reactions include diarrhoea. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Vectibix side effects in 57 year old male

Reported by a consumer/non-health professional from Hungary on 2012-08-01

Patient: 57 year old male, weighing 72.0 kg (158.4 pounds)

Reactions: Rash Pustular, Diarrhoea, Sepsis, Acne

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vectibix
    Dosage: 430 mg, one time dose
    Indication: Colorectal Cancer
    Start date: 2012-05-09
    End date: 2012-05-09

Vectibix
    Indication: Metastases To Liver

Vectibix
    Indication: Metastases To Lung

Other drugs received by patient: Dalteparin Sodium; Remeron; Fragmin; Analgesics



Possible Vectibix side effects in 62 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-12

Patient: 62 year old male, weighing 67.0 kg (147.5 pounds)

Reactions: Dyspnoea, Magnesium Deficiency, Skin Exfoliation, Nausea, Rash, Erythema, Skin Irritation, Skin Fissures, Pruritus Generalised, Diarrhoea, Neoplasm Malignant, Skin Lesion, Respiratory Arrest, Cough, Adrenal Mass

Adverse event resulted in: death

Drug(s) suspected as cause:
Vectibix
    Dosage: 400 mg, q2wk
    Start date: 2011-04-12
    End date: 2011-04-13

Vectibix
    Dosage: 6 mg/kg, q2wk
    Indication: Colorectal Cancer
    Start date: 2010-12-21
    End date: 2011-03-28

Magnesium Sulfate
    Dosage: unk
    Indication: Magnesium Deficiency
    Start date: 2011-02-01
    End date: 2011-04-15



Possible Vectibix side effects in 58 year old male

Reported by a consumer/non-health professional from France on 2012-04-03

Patient: 58 year old male

Reactions: Diarrhoea, Septic Shock, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vectibix

Other drugs received by patient: Folfiri



Possible Vectibix side effects in 72 year old male

Reported by a physician from United States on 2012-04-03

Patient: 72 year old male

Reactions: Weight Decreased, Colon Cancer, Diarrhoea, Skin Toxicity, Toxicity To Various Agents, Disease Progression

Drug(s) suspected as cause:
Vectibix
    Dosage: 6 mg, q2wk
    Indication: Colon Cancer Metastatic
    Start date: 2010-04-01

Oxaliplatin
    Dosage: unk
    Indication: Colorectal Cancer
    Start date: 2007-12-01

Capecitabine
    Dosage: unk
    Indication: Colorectal Cancer Metastatic

Bevacizumab
    Dosage: unk
    Indication: Colorectal Cancer
    Start date: 2007-12-01

Fluorouracil
    Dosage: unk
    Indication: Colorectal Cancer
    Start date: 2007-12-01

Leucovorin Calcium
    Dosage: unk
    Indication: Colorectal Cancer
    Start date: 2007-12-01

Other drugs received by patient: Irinotecan HCL



Possible Vectibix side effects in 61 year old male

Reported by a consumer/non-health professional from Greece on 2012-03-08

Patient: 61 year old male, weighing 60.0 kg (132.0 pounds)

Reactions: Drug Ineffective, Pyrexia, Myalgia, Dermatitis, Diarrhoea, Oedema Peripheral, Thrombophlebitis, Irritable Bowel Syndrome, Gastrointestinal Tract Irritation, Deep Vein Thrombosis

Drug(s) suspected as cause:
Avastin
    Dosage: 6 months
    Indication: Rectal Neoplasm
    Start date: 2011-02-01

Avastin
    Indication: Metastases To Liver
    Start date: 2011-08-28
    End date: 2011-11-04

Vectibix
    Indication: Metastases To Liver

Xeloda
    Dosage: dose : 5 x 500 mg, freq: 3 in the morning, 2 at night for 14 days foll by 7 day discontinuation pd
    Administration route: Oral
    Indication: Colorectal Cancer
    Start date: 2011-02-13
    End date: 2011-08-17

Oxaliplatin
    Indication: Metastases To Liver
    Start date: 2012-02-29

Oxaliplatin
    Indication: Rectal Neoplasm

Xeloda

Irinotecan HCL
    Dosage: 6 months
    Indication: Metastases To Liver
    Start date: 2011-08-28
    End date: 2011-11-04

Irinotecan HCL
    Dosage: as required, for 6 months
    Indication: Rectal Neoplasm
    Start date: 2011-02-01

Vectibix
    Dosage: as required
    Indication: Rectal Neoplasm
    Start date: 2012-02-29



Possible Vectibix side effects in 84 year old male

Reported by a physician from Netherlands on 2012-01-24

Patient: 84 year old male, weighing 60.0 kg (132.0 pounds)

Reactions: Death, Frequent Bowel Movements, Neoplasm Malignant, Diarrhoea

Adverse event resulted in: death

Drug(s) suspected as cause:
Vectibix

Other drugs received by patient: Loperamide



Possible Vectibix side effects in 59 year old male

Reported by a physician from United States on 2012-01-03

Patient: 59 year old male, weighing 70.3 kg (154.6 pounds)

Reactions: Ventricular Hypokinesia, Dyspnoea, Vomiting, Nausea, Hypotension, Rash, Cardiomyopathy, Small Intestinal Obstruction, Renal Failure, Diarrhoea, Dehydration, Myocarditis, Cardiac Failure Congestive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vectibix

Vectibix
    Dosage: 420 mg, q2wk
    Indication: Rectal Cancer Metastatic
    Start date: 2011-03-31
    End date: 2011-04-14

Other drugs received by patient: Norvasc; Aranesp; Protonix; Atenolol; Zoloft; Xgeva



Possible Vectibix side effects in 61 year old

Reported by a physician from United States on 2011-11-21

Patient: 61 year old

Reactions: Pruritus Generalised, Magnesium Deficiency, Diarrhoea, Erythema, Skin Fissures, Skin Irritation

Drug(s) suspected as cause:
Vectibix

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