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Vandetanib (Vandetanib) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (19)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Vandetanib life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Vandetanib side effects in female

Reported by a physician from Poland on 2012-07-11

Patient: female

Reactions: Renal Failure, Hypercalcaemia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Pamidronate Disodium
    Dosage: as required
    Indication: Metastases To Spine
    Start date: 2012-04-01
    End date: 2012-06-12

Vandetanib
    Administration route: Oral
    Start date: 2011-09-03

Vandetanib
    Administration route: Oral
    Indication: Thyroid Cancer
    Start date: 2011-08-16

Other drugs received by patient: Euthyrox N; Calperos; Magne B6; Pantoprazole; Euthyrox N; Loperamide; Alfadiol; Pramolan; Calperos; Potassium Chloride



Possible Vandetanib side effects in female

Reported by a physician from Poland on 2012-06-29

Patient: female

Reactions: Renal Failure, Hypercalcaemia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib
    Administration route: Oral
    Indication: Thyroid Cancer
    Start date: 2011-08-16

Pamidronate Disodium
    Dosage: as required
    Indication: Metastases To Spine
    Start date: 2012-04-01
    End date: 2012-06-12

Vandetanib
    Administration route: Oral
    Start date: 2011-09-03

Other drugs received by patient: Loperamide; Pantoprazole; Magne B6; Calperos; Potassium Chloride; Euthyrox N; Calperos; Alfadiol; Euthyrox N; Pramolan



Possible Vandetanib side effects in female

Reported by a physician from Poland on 2012-06-29

Patient: female

Reactions: Renal Failure, Hypercalcaemia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Pamidronate Disodium
    Dosage: as required
    Indication: Metastases To Spine
    Start date: 2012-04-01
    End date: 2012-06-12

Vandetanib
    Administration route: Oral
    Indication: Thyroid Cancer
    Start date: 2011-08-16

Vandetanib
    Administration route: Oral
    Start date: 2011-09-03

Other drugs received by patient: Pramolan; Calperos; Loperamide; Euthyrox N; Pantoprazole; Alfadiol; Magne B6; Euthyrox N; Calperos; Potassium Chloride



Possible Vandetanib side effects in female

Reported by a physician from Belgium on 2012-06-26

Patient: female

Reactions: Large Intestine Perforation, Intestinal Obstruction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib
    Administration route: Oral
    Indication: Thyroid Cancer
    Start date: 2011-05-21
    End date: 2011-05-27

Vandetanib
    Administration route: Oral
    Start date: 2011-06-16
    End date: 2011-06-16

Vandetanib
    Dosage: dose reduced
    Administration route: Oral
    Start date: 2011-06-17
    End date: 2011-07-01

Other drugs received by patient: Lorazepam; Zometa; Alpha LEO; Loramet; Polyethylene Glycol; Pantoprazole; Targinact; Laxoberon; Calcium; Elthyrone; Litican; Oxycodone HCL; Imodium; Closan; Voltaren; Medrol; Redomex; MS Contin



Possible Vandetanib side effects in female

Reported by a physician from Belgium on 2012-06-18

Patient: female

Reactions: Large Intestine Perforation, Intestinal Obstruction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib
    Administration route: Oral
    Indication: Thyroid Cancer
    Start date: 2011-05-21
    End date: 2011-05-27

Vandetanib
    Administration route: Oral
    Start date: 2011-06-16
    End date: 2011-06-16

Vandetanib
    Dosage: dose reduced
    Administration route: Oral
    Start date: 2011-06-17
    End date: 2011-07-01

Other drugs received by patient: Calcium; Alpha LEO; MS Contin; Closan; Laxoberon; Litican; Zometa; Voltaren; Redomex; Oxynorm; Imodium; Elthyrone; Pantoprazole; Targinact; Polyethylene Glycol; Medrol; Loramet; Lorazepam



Possible Vandetanib side effects in 73 year old male

Reported by a consumer/non-health professional from United States on 2012-04-16

Patient: 73 year old male

Reactions: Dermatitis Acneiform, Electrocardiogram QT Prolonged, Dyspnoea, Nausea, Fatigue, Diarrhoea, Atrioventricular Block, Dizziness, Memory Impairment, Cough

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Vandetanib

Other drugs received by patient: Lorazepam; Flomax; Proscar; Synthroid; Prochlorperazine Maleate



Possible Vandetanib side effects in male

Reported by a physician from United States on 2012-04-05

Patient: male

Reactions: Anaemia, Gastrointestinal Arteriovenous Malformation

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib

Other drugs received by patient: Ibuprofen; Calcitriol; Potassium Chloride; Ibuprofen; Oyster Shell Calcium; Codine Sulfate; Magnesium; Warfarin Sodium; Synthroid; Loretanide; Potassium Chloride; Potassium Chloride; Synthroid; Warfarin Sodium; Codine Sulfate; Metoprolol Succinate; Ibuprofen; Potassium Chloride; Warfarin Sodium; Imodium; Ibuprofen; Iron; Synthroid; Warfarin Sodium



Possible Vandetanib side effects in 56 year old female

Reported by a consumer/non-health professional from United States on 2012-03-05

Patient: 56 year old female, weighing 31.8 kg (70.0 pounds)

Reactions: Blood Pressure Increased, Pneumonia, Lung Infection, Urinary Tract Infection, Sepsis, Haemorrhagic Stroke, Coma

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib

Other drugs received by patient: Celexa; Thyroid Replacement Hormone; Blood Pressure Medications; Simvastatin; Tincture OF Opium; Octreotide Acetate



Possible Vandetanib side effects in male

Reported by a physician from Brazil on 2012-02-13

Patient: male

Reactions: Chest Pain

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib

Other drugs received by patient: Levothyroxine Sodium; Dipirona Sodica



Possible Vandetanib side effects in male

Reported by a physician from United States on 2012-02-03

Patient: male

Reactions: Anaemia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib

Other drugs received by patient: Ibuprofen; Warfarin Sodium; Metoprolol Succinate; Ibuprofen; Potassium Chloride; Oyster Shell Calcium; Codine Sulfate; Synthroid; Imodium; Magnesium; Loretanide; Potassium Chloride; Warfarin Sodium; Warfarin Sodium; Ibuprofen; Warfarin Sodium; Potassium Chloride; Synthroid; Ibuprofen; Iron; Calcitriol; Codine Sulfate; Potassium Chloride; Synthroid



Possible Vandetanib side effects in female

Reported by a physician from Belgium on 2012-01-24

Patient: female

Reactions: Large Intestine Perforation, Intestinal Obstruction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib
    Administration route: Oral
    Start date: 2011-06-16
    End date: 2011-06-16

Vandetanib
    Administration route: Oral
    Indication: Thyroid Cancer
    Start date: 2011-05-21
    End date: 2011-05-27

Vandetanib
    Dosage: dose reduced
    Administration route: Oral
    Start date: 2011-06-17
    End date: 2011-07-01

Other drugs received by patient: Loramet; Medrol; Voltaren; Litican; MS Contin; Polyethylene Glycol; Oxycodone HCL; Elthyrone; Calcium; Naloxone HCL; Redomex; Pantoprazole; Alpha LEO; Lorazepam; Closan; Laxoberon; Zometa; Imodium



Possible Vandetanib side effects in 55 year old female

Reported by a pharmacist from United States on 2012-01-13

Patient: 55 year old female, weighing 165.6 kg (364.2 pounds)

Reactions: Pulmonary Embolism

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib
    Dosage: 100mg
    Administration route: Oral
    Indication: Malignant Peritoneal Neoplasm
    Start date: 2011-09-08
    End date: 2011-09-18

Vandetanib
    Dosage: 100mg
    Administration route: Oral
    Indication: Ovarian Cancer
    Start date: 2011-09-08
    End date: 2011-09-18



Possible Vandetanib side effects in male

Reported by a physician from Brazil on 2012-01-09

Patient: male

Reactions: Angina Pectoris

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib

Other drugs received by patient: Levothyroxine Sodium; Dipirona Sodica



Possible Vandetanib side effects in 45 year old male

Reported by a consumer/non-health professional from United States on 2011-12-12

Patient: 45 year old male, weighing 61.2 kg (134.6 pounds)

Reactions: Hypertensive Encephalopathy, Dysphagia, Stomatitis, Gastrointestinal Motility Disorder, Aspiration Tracheal, Headache, Constipation, Convulsion, Hypertensive Crisis, Fatigue, Pharyngeal Disorder, Diarrhoea, Chest Pain, Hypothyroidism, Leukoencephalopathy, Depression

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib
    Administration route: Oral
    Start date: 2011-10-17
    End date: 2011-10-30

Vandetanib
    Dosage: daily
    Administration route: Oral
    Indication: Thyroid Cancer

Vandetanib
    Dosage: daily
    Administration route: Oral
    Indication: Thyroid Cancer Metastatic

Vandetanib
    Administration route: Oral
    Start date: 2011-10-17
    End date: 2011-10-30

Other drugs received by patient: Morphine Sulfate; Amlodipine Besylate; Valproate Sodium; Ambien; Celexa; Anticonvulsant; Calcium 600 + D; Potassium Chloride; Balanced B Complex 50; Oxycodone HCL; Oxycodone HCL; Oxycodone HCL; Toprol-XL; Plavix; Morphine Sulfate; Torsemide; Synthroid; Aspirin; Ambien; Protonix; Lorazepam; Keppra; Plavix



Possible Vandetanib side effects in 914 month old female

Reported by a physician from United States on 2011-12-02

Patient: 914 month old female, weighing 68.0 kg (149.6 pounds)

Reactions: White Blood Cell Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Docetaxel
    Indication: Ovarian Epithelial Cancer
    Start date: 2011-06-02
    End date: 2011-08-25

Vandetanib
    Administration route: Oral
    Indication: Ovarian Epithelial Cancer
    Start date: 2011-06-02
    End date: 2011-10-09

Docetaxel
    Dosage: dose reduced
    Start date: 2011-09-15

Vandetanib
    Administration route: Oral
    Start date: 2011-10-17



Possible Vandetanib side effects in male

Reported by a physician from France on 2011-11-21

Patient: male, weighing 75.0 kg (165.0 pounds)

Reactions: Dyspnoea

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Vandetanib
    Administration route: Oral
    Indication: Thyroid Cancer
    Start date: 2011-10-03
    End date: 2011-10-18

Vandetanib
    Administration route: Oral
    Start date: 2011-10-20

Other drugs received by patient: Morphine Sulfate; Potassium; Morphine Sulfate; Levothyroxine Sodium; Spironolactone; Irbesartan; Irbesartan; Umuline; Spironolactone



Possible Vandetanib side effects in 56 year old female

Reported by a physician from United States on 2011-11-02

Patient: 56 year old female, weighing 60.3 kg (132.7 pounds)

Reactions: Cerebrovascular Accident

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Vandetanib

Other drugs received by patient: Dilaudid; Prozac; Xanax; Calcium; Synthroid; Miralax; Coumadin; Restoril; Klor-CON M20; MS Contin; Rocaltrol



Possible Vandetanib side effects in male

Reported by a physician from France on 2011-10-24

Patient: male, weighing 75.0 kg (165.0 pounds)

Reactions: Dyspnoea

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Vandetanib

Other drugs received by patient: Levothyroxine Sodium; Morphine Sulfate; Potassium; Irbesartan; Umuline; Spironolactone; Spironolactone; Irbesartan; Morphine Sulfate



Possible Vandetanib side effects in female

Reported by a physician from Belgium on 2011-10-17

Patient: female

Reactions: Intestinal Perforation, Intestinal Obstruction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vandetanib
    Administration route: Oral
    Start date: 2011-06-16
    End date: 2011-06-16

Vandetanib
    Administration route: Oral
    Indication: Thyroid Cancer
    Start date: 2011-05-21
    End date: 2011-05-27

Vandetanib
    Dosage: dose reduced
    Administration route: Oral
    Start date: 2011-06-17
    End date: 2011-07-01

Other drugs received by patient: Targinact; Laxoberon; Litican; Oxycodone HCL; Lorazepam; Closan; Polyethylene Glycol; Zometa; Imodium; Calcium Carbonate; Elthyrone; Loramet; Alpha LEO; Voltaren; Pantoprazole; Medrol; Redomex; MS Contin

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