Index of reports
> Disability (19)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Tykerb (Lapatinib) disability. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Tykerb side effects in 68 year old female
Reported by a physician from Japan on 2012-07-19
Patient: 68 year old female
Reactions: Skin Disorder, Palmar-Plantar Erythrodysaesthesia Syndrome
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Tykerb
Dosage: dosage is uncertain.
Administration route: Oral
Indication: Breast Cancer Metastatic
Xeloda
Administration route: Oral
Start date: 2011-04-01
End date: 2011-06-24
Xeloda
Administration route: Oral
Indication: Breast Cancer Metastatic
Start date: 2010-09-24
End date: 2011-03-29
Tykerb
Dosage: amount of 80%
Administration route: Oral
Tykerb
Dosage: dosage is uncertain.
Administration route: Oral
Xeloda
Dosage: dosage is uncertain.
Administration route: Oral
Possible Tykerb side effects in female
Reported by a physician from Japan on 2012-06-18
Patient: female, weighing 51.0 kg (112.2 pounds)
Reactions: Pruritus, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Start date: 2011-09-12
End date: 2011-11-13
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Start date: 2011-12-05
End date: 2012-02-20
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2011-09-12
End date: 2012-02-20
Xeloda
Dosage: 900mg per day
Administration route: Oral
Start date: 2011-11-14
End date: 2011-12-04
Other drugs received by patient: Crestor; Amlodipine
Possible Tykerb side effects in 11 year old female
Reported by a physician from United States on 2012-05-11
Patient: 11 year old female, weighing 38.0 kg (83.6 pounds)
Reactions: Diarrhoea
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Tykerb
Other drugs received by patient: Vitamin TAB; Afinitor
Possible Tykerb side effects in female
Reported by a physician from Japan on 2012-05-03
Patient: female, weighing 56.0 kg (123.2 pounds)
Reactions: Pneumonia Bacterial
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Xeloda
Dosage: 3000mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-04-23
End date: 2011-05-30
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Start date: 2011-06-25
End date: 2011-12-16
Xeloda
Dosage: 3000mg per day
Administration route: Oral
Start date: 2011-06-25
End date: 2011-12-16
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2011-04-23
Tykerb
Administration route: Oral
Start date: 2011-05-14
Tykerb
Dosage: 1250mg per day
Administration route: Oral
End date: 2011-05-30
Other drugs received by patient: Pydoxal
Possible Tykerb side effects in female
Reported by a physician from Japan on 2012-05-02
Patient: female, weighing 51.0 kg (112.2 pounds)
Reactions: Pruritus, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Start date: 2011-12-05
End date: 2012-02-20
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-09-12
End date: 2011-11-13
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2011-09-12
End date: 2012-02-20
Xeloda
Dosage: 900mg per day
Administration route: Oral
Start date: 2011-11-14
End date: 2011-12-04
Other drugs received by patient: Amlodipine; Crestor
Possible Tykerb side effects in 63 year old female
Reported by a consumer/non-health professional from United States on 2012-04-27
Patient: 63 year old female
Reactions: Corneal Erosion, Blindness
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Tykerb
Possible Tykerb side effects in 63 year old female
Reported by a consumer/non-health professional from United States on 2012-04-12
Patient: 63 year old female
Reactions: Corneal Erosion, Blindness
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Tykerb
Possible Tykerb side effects in 81 year old female
Reported by a consumer/non-health professional from United States on 2012-04-11
Patient: 81 year old female, weighing 65.5 kg (144.1 pounds)
Reactions: Thrombosis, Intestinal Ischaemia, Diarrhoea, International Normalised Ratio Increased, Coagulopathy, Hypoxia, Intestinal Infarction
Adverse event resulted in: life threatening event, hospitalization, disablity
Drug(s) suspected as cause:
Coumadin
Indication: Atrial Fibrillation
End date: 2012-02-21
Tykerb
Dosage: 250mg three times per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2012-02-01
End date: 2012-02-19
Other drugs received by patient: Xeloda
Possible Tykerb side effects in female
Reported by a physician from Japan on 2012-03-20
Patient: female, weighing 56.0 kg (123.2 pounds)
Reactions: Hepatic Function Abnormal, Palmar-Plantar Erythrodysaesthesia Syndrome, Femoral Neck Fracture, Hepatic Enzyme Increased
Adverse event resulted in: life threatening event, disablity
Drug(s) suspected as cause:
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2010-10-12
End date: 2011-06-21
Xeloda
Dosage: 1800mg per day
Administration route: Oral
Start date: 2010-10-12
End date: 2011-06-14
Other drugs received by patient: Lendormin; Cortril; Famotidine; Chinese Medicine; Decadron; Chinese Medicine; Desmopressin Acetate
Possible Tykerb side effects in 81 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-20
Patient: 81 year old female
Reactions: Intestinal Ischaemia, Thrombosis, Diarrhoea, Coagulopathy, International Normalised Ratio Increased, Hypoxia
Adverse event resulted in: life threatening event, hospitalization, disablity
Drug(s) suspected as cause:
Coumadin
Indication: Product Used FOR Unknown Indication
Tykerb
Dosage: 250mg three times per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2012-02-01
End date: 2012-02-19
Other drugs received by patient: Xeloda
Possible Tykerb side effects in female
Reported by a physician from Japan on 2012-03-14
Patient: female, weighing 56.0 kg (123.2 pounds)
Reactions: Paronychia, Ulcerative Keratitis, Rash
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-04-06
End date: 2011-05-19
Xeloda
Dosage: 900mg per day
Administration route: Oral
Start date: 2011-05-20
End date: 2011-08-04
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Start date: 2011-08-05
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2011-04-06
Other drugs received by patient: Loperamide HCL
Possible Tykerb side effects in female
Reported by a physician from Japan on 2012-03-02
Patient: female, weighing 56.0 kg (123.2 pounds)
Reactions: Hepatic Function Abnormal, Palmar-Plantar Erythrodysaesthesia Syndrome, Femoral Neck Fracture, Hepatic Enzyme Increased
Adverse event resulted in: life threatening event, disablity
Drug(s) suspected as cause:
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2010-10-12
End date: 2011-06-21
Xeloda
Dosage: 1800mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2010-10-12
End date: 2011-06-14
Other drugs received by patient: Desmopressin Acetate; Cortril; Chinese Medicine; Lendormin; Chinese Medicine; Decadron; Famotidine
Possible Tykerb side effects in female
Reported by a physician from Japan on 2012-02-07
Patient: female, weighing 47.0 kg (103.4 pounds)
Reactions: Skin Disorder
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2009-12-30
End date: 2010-03-24
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2009-12-30
End date: 2010-03-24
Possible Tykerb side effects in female
Reported by a physician from Japan on 2012-01-26
Patient: female, weighing 42.0 kg (92.4 pounds)
Reactions: Renal Impairment, Cardiac Disorder
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2009-12-09
End date: 2009-12-19
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Start date: 2010-01-19
End date: 2010-04-13
Xeloda
Dosage: 2400mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2009-12-09
End date: 2009-12-19
Xeloda
Dosage: 2400mg per day
Administration route: Oral
Start date: 2010-01-06
End date: 2010-04-13
Other drugs received by patient: Loxonin; Selbex; Pydoxal
Possible Tykerb side effects in female
Reported by a physician from Japan on 2012-01-16
Patient: female, weighing 56.0 kg (123.2 pounds)
Reactions: Paronychia, Ulcerative Keratitis, Rash
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Xeloda
Dosage: 900mg per day
Administration route: Oral
Start date: 2011-05-27
End date: 2011-08-04
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Start date: 2011-08-05
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2011-04-06
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-04-06
End date: 2011-05-26
Other drugs received by patient: Loperamide HCL
Possible Tykerb side effects in female
Reported by a physician from Japan on 2011-12-29
Patient: female, weighing 56.0 kg (123.2 pounds)
Reactions: Muscle Spasms
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Xeloda
Dosage: 3000mg per day
Administration route: Oral
Start date: 2009-09-05
End date: 2010-07-30
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2009-09-05
Other drugs received by patient: Famotidine
Possible Tykerb side effects in 63 year old female
Reported by a consumer/non-health professional from United States on 2011-11-11
Patient: 63 year old female, weighing 87.7 kg (192.9 pounds)
Reactions: Subdural Haematoma, Haematocrit Decreased, Haematoma Evacuation, Ecchymosis, Pneumocephalus, Fall, Extradural Haematoma
Adverse event resulted in: life threatening event, hospitalization, disablity
Drug(s) suspected as cause:
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Warfarin Sodium
Dosage: 3mg per day
Administration route: Oral
Indication: Cardioversion
End date: 2011-10-01
Other drugs received by patient: Keppra; Zyprexa; Dilantin; Toprol-XL; Levophed; Haldol; Vitamin D; Femara; Amiodarone HCL; Lamictal
Possible Tykerb side effects in 63 year old female
Reported by a pharmacist from United States on 2011-10-26
Patient: 63 year old female
Reactions: Depressed Level of Consciousness, Fall, Haematoma
Adverse event resulted in: life threatening event, hospitalization, disablity
Drug(s) suspected as cause:
Tykerb
Other drugs received by patient: Femara
Possible Tykerb side effects in female
Reported by a physician from Japan on 2011-10-06
Patient: female, weighing 47.0 kg (103.4 pounds)
Reactions: Skin Disorder
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Tykerb
Dosage: 1250mg per day
Administration route: Oral
Indication: Breast Cancer
Start date: 2009-12-30
End date: 2010-03-24
Xeloda
Dosage: 1200mg per day
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2009-12-30
End date: 2010-03-24
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