DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Tykerb (Lapatinib) - Palmar-Plantar Erythrodysaesthesia Syndrome - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Palmar-Plantar Erythrodysaesthesia Syndrome (84)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Tykerb (Lapatinib) where reactions include palmar-plantar erythrodysaesthesia syndrome. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 84   Next >>

Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-21

Patient: female

Reactions: Defaecation Urgency, Pruritus, Coagulopathy, Central Nervous System Lesion, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypoaesthesia, Neoplasm, Nail Infection, Diarrhoea, Dysphonia, Oral Pain, Skin Lesion, Gastrointestinal Sounds Abnormal, Brain Neoplasm, Eye Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tamoxifen Citrate
    Indication: Product Used FOR Unknown Indication

Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-14

Xeloda
    Dosage: 500mg per day
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-14



Possible Tykerb side effects in 60 year old female

Reported by a consumer/non-health professional from United States on 2012-08-06

Patient: 60 year old female

Reactions: Skin Exfoliation, Adverse Drug Reaction, Palmar-Plantar Erythrodysaesthesia Syndrome

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-03

Patient: female

Reactions: Central Nervous System Lesion, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypoaesthesia, Nail Infection, Diarrhoea, Oral Pain, Skin Lesion, Eye Disorder, Brain Neoplasm

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-14

Xeloda
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-14



Possible Tykerb side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient:

Reactions: Skin Chapped, Pruritus, Pain in Extremity, Palmar-Plantar Erythrodysaesthesia Syndrome, Drug Interaction, Malaise, Diarrhoea, Upper Respiratory Tract Infection, Adverse Event

Drug(s) suspected as cause:
Janumet
    Administration route: Oral

Tykerb
    Dosage: 1500 mg, qd
    Administration route: Oral



Possible Tykerb side effects in 46 year old female

Reported by a physician from Canada on 2012-07-26

Patient: 46 year old female

Reactions: Musculoskeletal Disorder, Palmar-Plantar Erythrodysaesthesia Syndrome, DRY Skin, Erythema

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Xeloda
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in 41 year old female

Reported by a pharmacist from Canada on 2012-07-26

Patient: 41 year old female

Reactions: Breast Cancer, Stomatitis, Skin Exfoliation, Metastases To Liver, Palmar-Plantar Erythrodysaesthesia Syndrome, Condition Aggravated, Erythema

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Xeloda
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Docusate Sodium; Senokot; Tylenol with Codeine #3 (United States)



Possible Tykerb side effects in 68 year old female

Reported by a consumer/non-health professional from Canada on 2012-07-23

Patient: 68 year old female

Reactions: Stomatitis, Eye Discharge, Palmar-Plantar Erythrodysaesthesia Syndrome, Erythema, Neoplasm Malignant, Oedema Peripheral, Lacrimation Increased, DRY Eye

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Xeloda
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Multivitamin - Unspecified; Thyroid Medication



Possible Tykerb side effects in 68 year old female

Reported by a physician from Japan on 2012-07-19

Patient: 68 year old female

Reactions: Skin Disorder, Palmar-Plantar Erythrodysaesthesia Syndrome

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Tykerb
    Dosage: dosage is uncertain.
    Administration route: Oral
    Indication: Breast Cancer Metastatic

Tykerb
    Dosage: amount of 80%
    Administration route: Oral

Tykerb
    Dosage: dosage is uncertain.
    Administration route: Oral

Xeloda
    Administration route: Oral
    Start date: 2011-04-01
    End date: 2011-06-24

Xeloda
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2010-09-24
    End date: 2011-03-29

Xeloda
    Dosage: dosage is uncertain.
    Administration route: Oral



Possible Tykerb side effects in female

Reported by a physician from Japan on 2012-07-19

Patient: female, weighing 62.0 kg (136.4 pounds)

Reactions: Hepatic Function Abnormal, Dizziness, Palmar-Plantar Erythrodysaesthesia Syndrome, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-10-19
    End date: 2012-01-19

Xeloda
    Dosage: 3600mg per day
    Administration route: Oral
    Start date: 2011-10-19
    End date: 2012-01-19

Other drugs received by patient: Alfarol; Famotidine; Aspirin; Pydoxal; Locoid; Urso 250; Mucosolvan; Influenza HA Vaccine; Lipitor; Amoban; Unknown; Unknown Drug



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-18

Patient: female

Reactions: Skin Chapped, Weight Decreased, Swelling Face, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Skin Reaction, LIP Pain, Erythema, Malaise, Fatigue, Oral Pain, Influenza

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Indication: Breast Cancer Metastatic
    Start date: 2012-01-01
    End date: 2012-07-06

Xeloda
    Dosage: 2000mg per day
    Indication: Breast Cancer
    Start date: 2012-01-01
    End date: 2012-07-06

Other drugs received by patient: Steroid



Possible Tykerb side effects in female

Reported by a physician from Japan on 2012-07-13

Patient: female, weighing 49.0 kg (107.8 pounds)

Reactions: Paronychia, Productive Cough, Pruritus, Stomatitis, Haemoptysis, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Headache, Diarrhoea, Pigmentation Disorder, Decreased Appetite

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2010-12-21
    End date: 2011-08-17

Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Start date: 2011-09-27
    End date: 2011-12-18

Xeloda
    Dosage: 3000mg per day
    Administration route: Oral
    Start date: 2010-12-21
    End date: 2011-08-17

Xeloda
    Dosage: 2700mg per day
    Administration route: Oral
    Start date: 2011-09-27
    End date: 2011-10-10

Xeloda
    Dosage: 2400mg per day
    Administration route: Oral
    Start date: 2011-10-18
    End date: 2011-11-21

Xeloda
    Dosage: 1800mg per day
    Administration route: Oral
    Start date: 2011-11-29
    End date: 2011-12-12

Other drugs received by patient: Isosorbide Dinitrate; Levothyroxine Sodium; Pydoxal; Decadron; Locoid; Vitamin A Ointment; Clindamycin Phosphate; Myser



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-05

Patient: female

Reactions: Central Nervous System Lesion, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypoaesthesia, Nail Infection, Diarrhoea, Oral Pain, Skin Lesion, Eye Disorder, Brain Neoplasm

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-14

Xeloda
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-14



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-05

Patient: female

Reactions: Dyspnoea, Chest Discomfort, Pain, Palmar-Plantar Erythrodysaesthesia Syndrome, Drug Interaction, Erythema, Paraesthesia, Malaise, Insomnia

Drug(s) suspected as cause:
Tykerb
    Indication: Breast Cancer
    Start date: 2012-05-23

Xeloda
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-23

Zoloft
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-29

Patient: female

Reactions: Paronychia, Inappropriate Schedule of Drug Administration, Diarrhoea, Nausea, Ingrowing Nail, Palmar-Plantar Erythrodysaesthesia Syndrome, Treatment Noncompliance, Blister

Drug(s) suspected as cause:
Tykerb
    Dosage: 1000mg see dosage text
    Administration route: Oral
    Indication: Breast Cancer

Xeloda
    Dosage: 3tab see dosage text
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in 73 year old female

Reported by a consumer/non-health professional from United States on 2012-06-29

Patient: 73 year old female

Reactions: Diarrhoea, Adverse Drug Reaction, Palmar-Plantar Erythrodysaesthesia Syndrome

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 57 year old female

Reported by a consumer/non-health professional from United States on 2012-06-28

Patient: 57 year old female

Reactions: Diarrhoea, Mouth Ulceration, Palmar-Plantar Erythrodysaesthesia Syndrome, Erythema, Gastroenteritis Viral, Paraesthesia, Blister

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Indication: Breast Cancer
    Start date: 2011-11-01

Xeloda
    Start date: 2011-11-01



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-28

Patient: female

Reactions: Palmar-Plantar Erythrodysaesthesia Syndrome, DRY Eye

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-27

Patient: female

Reactions: Stomatitis, Diarrhoea, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Peripheral Sensory Neuropathy

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-21

Patient: female

Reactions: White Blood Cell Count Decreased, Back Pain, Pain in Extremity, Therapeutic Response Unexpected, Palmar-Plantar Erythrodysaesthesia Syndrome, Headache, Metastases To Spine, Musculoskeletal Stiffness, Brain Neoplasm

Drug(s) suspected as cause:
Herceptin
    Dosage: first therapy of herceptin

Herceptin
    Start date: 2012-01-01

Herceptin
    Indication: Breast Cancer
    Start date: 2012-01-12

Herceptin
    Start date: 2012-01-01

Herceptin
    Dosage: reduction frequency
    Start date: 2012-01-01

Herceptin
    Start date: 2012-01-01

Navelbine
    Indication: Breast Cancer

Navelbine
    Dosage: dose reduce three weeks on adnone week off

Taxol
    Indication: Breast Cancer

Tykerb
    Indication: Breast Cancer
    Start date: 2009-12-01

Xeloda
    Dosage: two week on and one week off.
    Indication: Breast Cancer
    Start date: 2009-12-01

Xeloda
    Start date: 2010-11-01



Possible Tykerb side effects in female

Reported by a physician from Japan on 2012-06-18

Patient: female, weighing 51.0 kg (112.2 pounds)

Reactions: Pruritus, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-09-12
    End date: 2012-02-20

Xeloda
    Dosage: 1200mg per day
    Administration route: Oral
    Start date: 2011-09-12
    End date: 2011-11-13

Xeloda
    Dosage: 1200mg per day
    Administration route: Oral
    Start date: 2011-12-05
    End date: 2012-02-20

Xeloda
    Dosage: 900mg per day
    Administration route: Oral
    Start date: 2011-11-14
    End date: 2011-12-04

Other drugs received by patient: Crestor; Amlodipine



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-06-06

Patient: female

Reactions: Pain in Extremity, Lung Neoplasm, Palmar-Plantar Erythrodysaesthesia Syndrome, Erythema, Onychomadesis, Eructation, Dysphonia, Hiccups, Brain Neoplasm

Drug(s) suspected as cause:
Tykerb
    Indication: Breast Cancer
    Start date: 2011-06-01

Xeloda
    Indication: Breast Cancer
    Start date: 2011-06-01



Possible Tykerb side effects in 57 year old female

Reported by a physician from United States on 2012-05-23

Patient: 57 year old female

Reactions: Diarrhoea, Mouth Ulceration, Palmar-Plantar Erythrodysaesthesia Syndrome, Erythema, Blister, Paraesthesia, Gastroenteritis Viral

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Indication: Breast Cancer
    Start date: 2011-11-01

Xeloda
    Start date: 2011-11-01



Possible Tykerb side effects in 74 year old female

Reported by a physician from Canada on 2012-05-23

Patient: 74 year old female

Reactions: Palmar-Plantar Erythrodysaesthesia Syndrome, Dyspnoea Exertional, Fatigue, Diarrhoea, Ocular Hyperaemia, Eye Swelling, Lacrimation Increased, Epistaxis, Muscle Spasms

Drug(s) suspected as cause:
Tykerb

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Xeloda
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Atenolol; Atacand; Synthroid



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-16

Patient: female

Reactions: Diarrhoea, Palmar-Plantar Erythrodysaesthesia Syndrome

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Zoloft; Anti-Cholesterol Medication; Xeloda



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-14

Patient: female

Reactions: Localised Infection, Pain, Palmar-Plantar Erythrodysaesthesia Syndrome, Gait Disturbance, Nail Infection

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mgd per day
    Administration route: Oral
    Indication: Breast Cancer

Xeloda
    Indication: Breast Cancer



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-11

Patient: female

Reactions: Diarrhoea, Palmar-Plantar Erythrodysaesthesia Syndrome

Drug(s) suspected as cause:
Herceptin
    Indication: Product Used FOR Unknown Indication

Tykerb
    Dosage: 1000mgd per day
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-11-05

Xeloda
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-11-05



Possible Tykerb side effects in 57 year old female

Reported by a consumer/non-health professional from United States on 2012-05-08

Patient: 57 year old female

Reactions: Diarrhoea, Mouth Ulceration, Palmar-Plantar Erythrodysaesthesia Syndrome, Gastroenteritis Viral

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Indication: Breast Cancer
    Start date: 2011-11-01

Xeloda
    Start date: 2011-11-01



Possible Tykerb side effects in 48 year old female

Reported by a physician from Hungary on 2012-05-08

Patient: 48 year old female

Reactions: Abdominal Pain Lower, Paronychia, Palmar-Plantar Erythrodysaesthesia Syndrome, Skin Reaction, Malaise, Diarrhoea, Nasal Inflammation, Vision Blurred, Dizziness

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Xeloda



Possible Tykerb side effects in female

Reported by a physician from Japan on 2012-05-02

Patient: female, weighing 51.0 kg (112.2 pounds)

Reactions: Pruritus, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-09-12
    End date: 2012-02-20

Xeloda
    Dosage: 1200mg per day
    Administration route: Oral
    Start date: 2011-12-05
    End date: 2012-02-20

Xeloda
    Dosage: 1200mg per day
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-09-12
    End date: 2011-11-13

Xeloda
    Dosage: 900mg per day
    Administration route: Oral
    Start date: 2011-11-14
    End date: 2011-12-04

Other drugs received by patient: Amlodipine; Crestor



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from Canada on 2012-04-25

Patient: female

Reactions: Skin Chapped, Palmar-Plantar Erythrodysaesthesia Syndrome

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-06-17

Xeloda
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Maxeran; Slow-K; Vitamin B Complex CAP; Zofran; Lomotil



 Page 1   Next >>

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2014