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Tykerb (Lapatinib) - Diarrhoea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Diarrhoea (332)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Tykerb (Lapatinib) where reactions include diarrhoea. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 332   Next >>

Possible Tykerb side effects in 69 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-27

Patient: 69 year old female

Reactions: Phlebitis, Breast Cancer, Fatigue, Diarrhoea, Decreased Appetite, Disease Progression

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in 63 year old female

Reported by a physician from Canada on 2012-08-27

Patient: 63 year old female

Reactions: Paronychia, Skin Chapped, Stomatitis, Haemorrhage, Diarrhoea

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Amitriptyline Hydrochloride; Atorvastatin Calcium; Lansoprazole; Metformin HCL



Possible Tykerb side effects in 86 year old female

Reported by a consumer/non-health professional from United States on 2012-08-24

Patient: 86 year old female, weighing 45.9 kg (101.0 pounds)

Reactions: Weight Decreased, Breast Cancer, Pain in Extremity, Hypoaesthesia, Metastasis, Fatigue, Diarrhoea, Oedema Peripheral, Nail Disorder

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Herceptin



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-24

Patient: female

Reactions: Diarrhoea, Neoplasm Malignant, Enteritis Infectious

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 55 year old female

Reported by a consumer/non-health professional from United States on 2012-08-24

Patient: 55 year old female

Reactions: Weight Decreased, Vomiting, Diarrhoea

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 66 year old female

Reported by a physician from Canada on 2012-08-22

Patient: 66 year old female

Reactions: Breast Cancer, Diarrhoea, Neoplasm Malignant, Dehydration, Ear Infection, Dizziness

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Capecitabine
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Ativan



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-21

Patient: female

Reactions: Defaecation Urgency, Pruritus, Coagulopathy, Central Nervous System Lesion, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypoaesthesia, Neoplasm, Nail Infection, Diarrhoea, Dysphonia, Oral Pain, Skin Lesion, Gastrointestinal Sounds Abnormal, Brain Neoplasm, Eye Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-14

Tamoxifen Citrate
    Indication: Product Used FOR Unknown Indication

Xeloda
    Dosage: 500mg per day
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-14



Possible Tykerb side effects in 35 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-20

Patient: 35 year old female

Reactions: Localised Infection, White Blood Cell Count Decreased, Diarrhoea, Neoplasm Malignant, Pyrexia, Disease Progression

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Levofloxacin; Imodium



Possible Tykerb side effects in 55 year old female

Reported by a consumer/non-health professional from Mexico on 2012-08-20

Patient: 55 year old female

Reactions: Fatigue, Diarrhoea, Hepatotoxicity, Rash, Disease Progression

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 60 year old female

Reported by a physician from Canada on 2012-08-20

Patient: 60 year old female

Reactions: Vomiting, Nausea, Diarrhoea, Neoplasm Malignant, Dehydration, Disease Progression, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral

Xeloda
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Hydromorphone Hydrochloride; Retinol; Prevacid; Micardis; Verapamil HCL; Celebrex; Colace; Vitamin D; Antihypertensive Medications; Actonel; Senokot



Possible Tykerb side effects in 62 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-20

Patient: 62 year old female

Reactions: Stomatitis, Renal Failure, Blood Potassium Decreased, Diarrhoea, Oral Pain, Skin Ulcer, Dehydration, Blood Sodium Decreased, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Xeloda
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Laxatives (Unk Ingredients); Metoclopramide; Desmopressin Acetate (Ddavp); Dexamethasone; Metoprolol Tartrate; Vitamin D; Hydromorphone Hydrochloride; Spironolactone; Aspirin; Slow-K; Pantoprazole



Possible Tykerb side effects in 51 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-20

Patient: 51 year old female

Reactions: Nasal Oedema, Breast Cancer Metastatic, Diarrhoea, Acne, Erythema, Disease Progression

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-09

Patient: female

Reactions: Diarrhoea, Enteritis Infectious

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-06

Patient: female

Reactions: Dyspnoea, Vomiting, Nausea, Headache, Pericardial Effusion, Dysgeusia, Diarrhoea, Chest Pain, Pulmonary Thrombosis, Decreased Appetite

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Xeloda
    Indication: Breast Cancer
    Start date: 2012-01-23
    End date: 2012-07-01

Tykerb
    Indication: Breast Cancer
    Start date: 2012-01-23
    End date: 2012-07-01



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-03

Patient: female

Reactions: Central Nervous System Lesion, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypoaesthesia, Nail Infection, Diarrhoea, Oral Pain, Skin Lesion, Eye Disorder, Brain Neoplasm

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-14

Xeloda
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-14



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-01

Patient: female

Reactions: Nausea, Hypotension, Neoplasm Progression, Hepatic Neoplasm, Fatigue, Lung Disorder, Diarrhoea, Dehydration, Asthenia, Decreased Appetite

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-05-18

Xeloda
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Ramipril



Possible Tykerb side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient:

Reactions: Skin Chapped, Pruritus, Pain in Extremity, Palmar-Plantar Erythrodysaesthesia Syndrome, Drug Interaction, Malaise, Diarrhoea, Upper Respiratory Tract Infection, Adverse Event

Drug(s) suspected as cause:
Janumet
    Administration route: Oral

Tykerb
    Dosage: 1500 mg, qd
    Administration route: Oral



Possible Tykerb side effects in 51 year old female

Reported by a physician from Canada on 2012-07-30

Patient: 51 year old female

Reactions: Vomiting, Tongue Discolouration, Diarrhoea, Insomnia, Asthenia, Decreased Appetite

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Norvasc; Prochlorperazine; Decadron; Docusate Sodium; Lactulose; Pantoprazole Sodium; Metformin Hydrochloride; Tylenol with Codeine #3 (United States)



Possible Tykerb side effects in 60 year old female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-07-27

Patient: 60 year old female

Reactions: Confusional State, Fatigue, Diarrhoea, Oedema Peripheral, Fall, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Xeloda
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Corticosteroid (Unk Ingredients)



Possible Tykerb side effects in 56 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-17

Patient: 56 year old female, weighing 77.0 kg (169.4 pounds)

Reactions: Metastatic Neoplasm, Chest Discomfort, Spondylolisthesis, Enthesopathy, Colon Neoplasm, Constipation, Cerebral Ischaemia, Osteoarthritis, Hepatic Cyst, Vitreous Floaters, Diarrhoea, Adverse Event, Rash Vesicular

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Diltiazem; Letrozole; Zofran; Imodium; Xeloda; Xanax; Potassium Chloride; Temazepam



Possible Tykerb side effects in female

Reported by a physician from Japan on 2012-07-13

Patient: female, weighing 49.0 kg (107.8 pounds)

Reactions: Paronychia, Productive Cough, Pruritus, Stomatitis, Haemoptysis, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Headache, Diarrhoea, Pigmentation Disorder, Decreased Appetite

Drug(s) suspected as cause:
Xeloda
    Dosage: 3000mg per day
    Administration route: Oral
    Start date: 2010-12-21
    End date: 2011-08-17

Xeloda
    Dosage: 2700mg per day
    Administration route: Oral
    Start date: 2011-09-27
    End date: 2011-10-10

Xeloda
    Dosage: 2400mg per day
    Administration route: Oral
    Start date: 2011-10-18
    End date: 2011-11-21

Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2010-12-21
    End date: 2011-08-17

Xeloda
    Dosage: 1800mg per day
    Administration route: Oral
    Start date: 2011-11-29
    End date: 2011-12-12

Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Start date: 2011-09-27
    End date: 2011-12-18

Other drugs received by patient: Isosorbide Dinitrate; Levothyroxine Sodium; Pydoxal; Decadron; Locoid; Vitamin A Ointment; Clindamycin Phosphate; Myser



Possible Tykerb side effects in 61 year old female

Reported by a consumer/non-health professional from United States on 2012-07-10

Patient: 61 year old female

Reactions: Nephrolithiasis, Incontinence, Diarrhoea

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-07-05

Patient: female

Reactions: Central Nervous System Lesion, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypoaesthesia, Nail Infection, Diarrhoea, Oral Pain, Skin Lesion, Eye Disorder, Brain Neoplasm

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-14

Xeloda
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-14



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-03

Patient: female

Reactions: Pneumonia, Diarrhoea, Somnolence, Constipation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-29

Patient: female

Reactions: Speech Disorder, Diarrhoea, Cerebrovascular Accident

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-29

Patient: female

Reactions: Paronychia, Inappropriate Schedule of Drug Administration, Diarrhoea, Nausea, Ingrowing Nail, Palmar-Plantar Erythrodysaesthesia Syndrome, Treatment Noncompliance, Blister

Drug(s) suspected as cause:
Xeloda
    Dosage: 3tab see dosage text
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Tykerb
    Dosage: 1000mg see dosage text
    Administration route: Oral
    Indication: Breast Cancer



Possible Tykerb side effects in 73 year old female

Reported by a consumer/non-health professional from United States on 2012-06-29

Patient: 73 year old female

Reactions: Diarrhoea, Adverse Drug Reaction, Palmar-Plantar Erythrodysaesthesia Syndrome

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 57 year old female

Reported by a consumer/non-health professional from United States on 2012-06-28

Patient: 57 year old female

Reactions: Diarrhoea, Mouth Ulceration, Palmar-Plantar Erythrodysaesthesia Syndrome, Erythema, Gastroenteritis Viral, Paraesthesia, Blister

Drug(s) suspected as cause:
Xeloda
    Start date: 2011-11-01

Tykerb
    Dosage: 1250mg per day
    Indication: Breast Cancer
    Start date: 2011-11-01



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-28

Patient: female

Reactions: Skin Chapped, Scab, Breast Neoplasm, Skin Hypertrophy, Disease Progression, Rhinalgia, Diarrhoea, Skin Ulcer, LIP Injury, Computerised Tomogram

Drug(s) suspected as cause:
Xeloda
    Dosage: 2000mg twice per day
    Administration route: Oral
    Indication: Breast Cancer

Tykerb
    Dosage: 1000mg per day
    Administration route: Oral
    Indication: Breast Cancer



Possible Tykerb side effects in 62 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-27

Patient: 62 year old female, weighing 72.9 kg (160.4 pounds)

Reactions: Weight Decreased, Electrocardiogram QT Prolonged, Blood Potassium Decreased, Diarrhoea, Drug Interaction, Electrolyte Imbalance

Drug(s) suspected as cause:
Tykerb
    Dosage: 1000mg per day
    Administration route: Oral
    Indication: Breast Cancer

Celexa

Other drugs received by patient: Trastuzumab; Potassium Acetate



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