DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Tykerb (Lapatinib) - Side Effect Reports to FDA

 
 



This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Tykerb (Lapatinib) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.

Reports by Event Outcome

All Cases (1062)
Death (166)
Life Threatening Events (24)
Disability (19)

Reports by Reaction Type

Diarrhoea (332)Death (117)Nausea (106)Fatigue (87)Palmar-Plantar Erythrodysaesthesia Syndrome (84)Rash (66)Vomiting (60)Decreased Appetite (46)Erythema (44)Disease Progression (44)Malaise (41)Neoplasm Malignant (39)

Below are a few examples of reports where side effects / adverse reactions may be related to Tykerb (Lapatinib). For a complete list or a specific selection of reports, please use the links above.

Possible Tykerb side effects in 69 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-27

Patient: 69 year old female

Reactions: Phlebitis, Breast Cancer, Fatigue, Diarrhoea, Decreased Appetite, Disease Progression

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in 76 year old female

Reported by a consumer/non-health professional from United States on 2012-08-27

Patient: 76 year old female

Reactions: Disease Progression

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Antiemetics



Possible Tykerb side effects in 63 year old female

Reported by a physician from Canada on 2012-08-27

Patient: 63 year old female

Reactions: Paronychia, Skin Chapped, Stomatitis, Haemorrhage, Diarrhoea

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Amitriptyline Hydrochloride; Atorvastatin Calcium; Lansoprazole; Metformin HCL



Possible Tykerb side effects in 46 year old female

Reported by a consumer/non-health professional from United States on 2012-08-27

Patient: 46 year old female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 51 year old female

Reported by a physician from Canada on 2012-08-27

Patient: 51 year old female

Reactions: Breast Cancer Metastatic, Neoplasm Malignant

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Oxycontin; Percocet



Possible Tykerb side effects in 55 year old female

Reported by a consumer/non-health professional from United States on 2012-08-24

Patient: 55 year old female

Reactions: Weight Decreased, Vomiting, Diarrhoea

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 62 year old female

Reported by a consumer/non-health professional from United States on 2012-08-24

Patient: 62 year old female, weighing 48.2 kg (106.0 pounds)

Reactions: Nail Disorder, Skin Atrophy, Blister

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 86 year old female

Reported by a consumer/non-health professional from United States on 2012-08-24

Patient: 86 year old female, weighing 45.9 kg (101.0 pounds)

Reactions: Weight Decreased, Breast Cancer, Pain in Extremity, Hypoaesthesia, Metastasis, Fatigue, Diarrhoea, Oedema Peripheral, Nail Disorder

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Herceptin



Possible Tykerb side effects in female

Reported by a physician from Japan on 2012-08-24

Patient: female

Reactions: White Blood Cell Count Decreased, RED Blood Cell Count Decreased, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Xeloda



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-24

Patient: female

Reactions: Diarrhoea, Neoplasm Malignant, Enteritis Infectious

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 50 year old female

Reported by a physician from Canada on 2012-08-24

Patient: 50 year old female

Reactions: Breast Cancer, Skin Exfoliation, DRY Skin, Paraesthesia, Fatigue, Neoplasm Malignant, Ocular Hyperaemia, Eye Swelling, Lacrimation Increased, Metastases To Central Nervous System

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in 51 year old female

Reported by a consumer/non-health professional from United States on 2012-08-23

Patient: 51 year old female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 60 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-23

Patient: 60 year old female

Reactions: Breast Cancer Metastatic, Neoplasm Malignant

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in 66 year old female

Reported by a physician from Canada on 2012-08-22

Patient: 66 year old female

Reactions: Breast Cancer, Diarrhoea, Neoplasm Malignant, Dehydration, Ear Infection, Dizziness

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Capecitabine
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Ativan



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-21

Patient: female

Reactions: Metastases To Liver, Metastases To Pelvis, Metastases To Central Nervous System, Convulsion

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Carbamazepine; Dexamethasone



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-21

Patient: female

Reactions: Defaecation Urgency, Pruritus, Coagulopathy, Central Nervous System Lesion, Palmar-Plantar Erythrodysaesthesia Syndrome, Hypoaesthesia, Neoplasm, Nail Infection, Diarrhoea, Dysphonia, Oral Pain, Skin Lesion, Gastrointestinal Sounds Abnormal, Brain Neoplasm, Eye Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb
    Dosage: 1250mg per day
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-14

Tamoxifen Citrate
    Indication: Product Used FOR Unknown Indication

Xeloda
    Dosage: 500mg per day
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-14



Possible Tykerb side effects in 51 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-20

Patient: 51 year old female

Reactions: Nasal Oedema, Breast Cancer Metastatic, Diarrhoea, Acne, Erythema, Disease Progression

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in 50 year old female

Reported by a physician from Mexico on 2012-08-20

Patient: 50 year old female

Reactions: Hepatotoxicity, Disease Progression

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 35 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-20

Patient: 35 year old female

Reactions: Localised Infection, White Blood Cell Count Decreased, Diarrhoea, Neoplasm Malignant, Pyrexia, Disease Progression

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Levofloxacin; Imodium



Possible Tykerb side effects in 54 year old female

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: 54 year old female, weighing 79.1 kg (174.0 pounds)

Reactions: Breast Cancer Metastatic, Neoplasm Malignant, Asthenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Abraxane; Halaven



Possible Tykerb side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 63 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-20

Patient: 63 year old female

Reactions: Breast Cancer Metastatic, Feeling Hot, Gait Disturbance, Erythema, Disease Progression

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Xeloda
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in 55 year old female

Reported by a consumer/non-health professional from Mexico on 2012-08-20

Patient: 55 year old female

Reactions: Fatigue, Diarrhoea, Hepatotoxicity, Rash, Disease Progression

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 62 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-20

Patient: 62 year old female

Reactions: Stomatitis, Renal Failure, Blood Potassium Decreased, Diarrhoea, Oral Pain, Skin Ulcer, Dehydration, Blood Sodium Decreased, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Xeloda
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Laxatives (Unk Ingredients); Metoclopramide; Desmopressin Acetate (Ddavp); Dexamethasone; Metoprolol Tartrate; Vitamin D; Hydromorphone Hydrochloride; Spironolactone; Aspirin; Slow-K; Pantoprazole



Possible Tykerb side effects in 60 year old female

Reported by a physician from Canada on 2012-08-20

Patient: 60 year old female

Reactions: Vomiting, Nausea, Diarrhoea, Neoplasm Malignant, Dehydration, Disease Progression, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Tykerb
    Administration route: Oral

Xeloda
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Hydromorphone Hydrochloride; Retinol; Prevacid; Micardis; Verapamil HCL; Celebrex; Colace; Vitamin D; Antihypertensive Medications; Actonel; Senokot



Possible Tykerb side effects in 55 year old female

Reported by a physician from Mexico on 2012-08-20

Patient: 55 year old female

Reactions: Hepatotoxicity, Disease Progression

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in female

Reported by a consumer/non-health professional from Canada on 2012-08-17

Patient: female

Reactions: Pain in Extremity, Asthenia, Paraesthesia, Hepatic Enzyme Increased, Inflammation

Drug(s) suspected as cause:
Tykerb

Other drugs received by patient: Xeloda



Possible Tykerb side effects in 63 year old female

Reported by a consumer/non-health professional from United States on 2012-08-15

Patient: 63 year old female

Reactions: Hospitalisation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tykerb



Possible Tykerb side effects in 60 year old female

Reported by a physician from Canada on 2012-08-15

Patient: 60 year old female

Reactions: Breast Cancer Metastatic, Neoplasm Malignant

Drug(s) suspected as cause:
Xeloda
    Indication: Product Used FOR Unknown Indication

Tykerb
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Tykerb side effects in female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-15

Patient: female

Reactions: Fatigue, Arteriospasm Coronary, Rash Pruritic

Drug(s) suspected as cause:
Raltitrexed
    Indication: Product Used FOR Unknown Indication

Xeloda
    Dosage: 2000mg per day
    Indication: Breast Cancer Metastatic
    Start date: 2012-07-20
    End date: 2012-07-23

Tykerb
    Dosage: 1000mg at night
    Indication: Breast Cancer Metastatic
    Start date: 2012-07-20

Other drugs received by patient: Phenergan HCL

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2014