This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Treanda (Bendamustine) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (756)
Death (63)
Life Threatening Events (49)
Disability (15)
Reports by Reaction Type
Pyrexia (67),
Rash (63),
White Blood Cell Count Decreased (38),
Platelet Count Decreased (33),
Neutrophil Count Decreased (32),
Pancytopenia (30),
Neutropenia (30),
Pneumonia (29),
Nausea (29),
Fatigue (28),
Dyspnoea (24),
Lymphocyte Count Decreased (23)
Below are a few examples of reports where side effects / adverse reactions may be related to Treanda (Bendamustine). For a complete list or a specific selection of reports, please use the links above.
Possible Treanda side effects in male
Reported by a physician from United States on 2012-08-24
Patient: male
Reactions: Myalgia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rituximab
Treanda
Indication: Chronic Lymphocytic Leukaemia
Possible Treanda side effects in 55 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24
Patient: 55 year old male
Reactions: Rash Generalised, Multi-Organ Failure, Lung Disorder, Heart Rate Increased, Bone Marrow Failure, Neutropenia, Gastrointestinal Tract Irritation, Thrombocytopenia, Stevens-Johnson Syndrome
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Treanda
Other drugs received by patient: Allopurinol; Rituximab
Possible Treanda side effects in 68 year old female
Reported by a physician from United States on 2012-08-23
Patient: 68 year old female, weighing 104.8 kg (230.7 pounds)
Reactions: Hypotension, Pancytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rituximab
Dosage: day 1 of each 28 day cycle,
Indication: non-Hodgkin's Lymphoma
Start date: 2012-03-27
End date: 2012-03-27
Treanda
Dosage: day 1 and 2 of each 28 day cycle
Indication: non-Hodgkin's Lymphoma
Start date: 2012-03-27
End date: 2012-03-28
Other drugs received by patient: Sertraline Hydrochloride; Ondansetron; Allopurinol; Colecalciferol; Genistein; Lactobacillus Acidophilus; Acyclovir; Furosemide; Omeprazole; Loperamide; Metoprolol Succinate; Genesa; Ibuprofen; Potassium Chloride; Tylox; Lorazepam; Zinc Sulfate; Prochlorperazine Maleate; Levothyroxine Sodium
Possible Treanda side effects in male
Reported by a physician from United Kingdom on 2012-08-23
Patient: male
Reactions: Respiratory Tract Infection
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dexamethasone
Dosage: 2.8571 milligram daily;
Administration route: Oral
Start date: 2012-03-30
End date: 2012-05-28
Thalidomide
Dosage: 100 milligram daily;
Administration route: Oral
Start date: 2012-03-30
End date: 2012-05-28
Treanda
Dosage: 8 milligram daily;
Start date: 2012-03-30
End date: 2012-05-25
Possible Treanda side effects in female
Reported by a physician from France on 2012-08-22
Patient: female, weighing 62.0 kg (136.4 pounds)
Reactions: Arrhythmia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rituximab
Start date: 2012-06-06
Treanda
Start date: 2012-06-06
Other drugs received by patient: Aspirin; Praxada; Minisintrom
Possible Treanda side effects in
Reported by a physician from Netherlands on 2012-08-21
Patient:
Reactions: Diarrhoea, Skin Exfoliation, Rash
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Lenalidomide
Start date: 2012-04-20
Rituximab
Start date: 2012-04-20
Treanda
Start date: 2012-04-20
Possible Treanda side effects in female
Reported by a physician from France on 2012-08-21
Patient: female, weighing 45.0 kg (99.0 pounds)
Reactions: Dyspnoea, Pleural Effusion, Pyrexia, Generalised Oedema
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Bortezomib
Dosage: 1.82 milligram daily;
Indication: Mantle Cell Lymphoma
Start date: 2012-02-02
Dexamethasone
Indication: Mantle Cell Lymphoma
Start date: 2012-02-02
Rituximab
Indication: Mantle Cell Lymphoma
Start date: 2012-02-01
Treanda
Indication: Mantle Cell Lymphoma
Start date: 2012-02-01
Other drugs received by patient: Pegfilgrastim
Possible Treanda side effects in female
Reported by a physician from France on 2012-08-21
Patient: female, weighing 45.0 kg (99.0 pounds)
Reactions: Dyspnoea, Pleural Effusion, Pyrexia, Generalised Oedema
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Bortezomib
Dosage: 1.82 milligram daily;
Indication: Mantle Cell Lymphoma
Start date: 2012-02-02
Dexamethasone
Indication: Mantle Cell Lymphoma
Start date: 2012-02-02
Rituximab
Indication: Mantle Cell Lymphoma
Start date: 2012-02-01
Treanda
Indication: Mantle Cell Lymphoma
Start date: 2012-02-01
Other drugs received by patient: Pegfilgrastim
Possible Treanda side effects in female
Reported by a physician from France on 2012-08-21
Patient: female, weighing 62.0 kg (136.4 pounds)
Reactions: Arrhythmia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rituximab
Start date: 2012-06-06
Treanda
Start date: 2012-06-06
Possible Treanda side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-20
Patient: male, weighing 54.0 kg (118.9 pounds)
Reactions: Tachycardia, Pneumothorax, Hypertension, Asthenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Treanda
Other drugs received by patient: Velcade
Possible Treanda side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20
Patient: female
Reactions: Aplasia Pure RED Cell
Drug(s) suspected as cause:
Rituximab
Treanda
Possible Treanda side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20
Patient: male
Reactions: Aplasia Pure RED Cell
Drug(s) suspected as cause:
Rituximab
Treanda
Possible Treanda side effects in female
Reported by a physician from France on 2012-08-17
Patient: female, weighing 62.0 kg (136.4 pounds)
Reactions: Arrhythmia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rituximab
Start date: 2012-06-06
Treanda
Start date: 2012-06-06
Possible Treanda side effects in 48 year old male
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-08-17
Patient: 48 year old male
Reactions: Stevens-Johnson Syndrome
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Treanda
Other drugs received by patient: Rituximab
Possible Treanda side effects in female
Reported by a physician from France on 2012-08-17
Patient: female, weighing 58.7 kg (129.1 pounds)
Reactions: Hypoglycaemia, Infection
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dexamethasone
Dosage: 40 milligram daily;
Indication: Mantle Cell Lymphoma
Start date: 2012-06-15
Mabthera
Indication: Mantle Cell Lymphoma
Start date: 2012-06-14
Treanda
Dosage: 147.6 milligram daily;
Indication: Mantle Cell Lymphoma
Start date: 2012-06-14
End date: 2012-06-15
Velcade
Indication: Mantle Cell Lymphoma
Start date: 2012-06-14
Other drugs received by patient: Sotalol HCL; Bactrim; Valacyclovir Hydrochloride; Glimepiride; Atorvastatin; Zolpidem; Potassium Chloride; Trandolapril; Glucophage
Possible Treanda side effects in male
Reported by a physician from United States on 2012-08-17
Patient: male
Reactions: White Blood Cell Count Decreased, Rash, Aplasia Pure RED Cell, Haemolytic Anaemia
Drug(s) suspected as cause:
Treanda
Other drugs received by patient: Allopurinol
Possible Treanda side effects in male
Reported by a physician from Japan on 2012-08-16
Patient: male
Reactions: Hyponatraemia, Full Blood Count Decreased, Hepatosplenomegaly, Pneumonia Cytomegaloviral
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Treanda
Other drugs received by patient: Allopurinol; Prednisolone; Tamsulosin Hydrochloride; Mecobalamin; Rituximab; Sulfamethoxazole and Trimethoprim; Amikacin Sulfate; Prednisolone Sodium Succinate INJ; Betamethasone Plus D-Chlorpheniramine Maleate
Possible Treanda side effects in male
Reported by a physician from Japan on 2012-08-16
Patient: male
Reactions: Haemolytic Anaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Treanda
Possible Treanda side effects in female
Reported by a physician from United Kingdom on 2012-08-16
Patient: female, weighing 72.6 kg (159.7 pounds)
Reactions: Psoriasis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Ofatumumab
Dosage: unknown/d
Indication: Chronic Lymphocytic Leukaemia
Start date: 2012-07-04
Treanda
Indication: Chronic Lymphocytic Leukaemia
Start date: 2012-07-04
Other drugs received by patient: Furosemide; Loratadine; Omeprazole; Amiloride Hydrochloride
Possible Treanda side effects in male
Reported by a physician from Germany on 2012-08-15
Patient: male
Reactions: Gastrointestinal Infection
Drug(s) suspected as cause:
Treanda
Possible Treanda side effects in 74 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-14
Patient: 74 year old male, weighing 66.1 kg (145.5 pounds)
Reactions: Pneumonia, Pancytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Treanda
Possible Treanda side effects in 66 year old male
Reported by a physician from Japan on 2012-08-14
Patient: 66 year old male
Reactions: Interstitial Lung Disease
Drug(s) suspected as cause:
Treanda
Other drugs received by patient: Rituximab
Possible Treanda side effects in male
Reported by a individual with unspecified qualification from France on 2012-08-13
Patient: male, weighing 96.0 kg (211.2 pounds)
Reactions: Ileus
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Mabthera
Dosage: uid/qd
Indication: Mantle Cell Lymphoma
Start date: 2012-07-09
Treanda
Dosage: uid/qd
Indication: Mantle Cell Lymphoma
Start date: 2012-07-09
Velcade
Dosage: uid/qd
Indication: Mantle Cell Lymphoma
Start date: 2012-07-09
Other drugs received by patient: Lyrica; Gliclazide; Plavix; Prazosin HCL
Possible Treanda side effects in
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-13
Patient:
Reactions: Cardiotoxicity
Drug(s) suspected as cause:
Treanda
Possible Treanda side effects in male
Reported by a physician from France on 2012-08-13
Patient: male, weighing 180.0 kg (396.0 pounds)
Reactions: Oral Candidiasis, Nausea
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Bortezomib
Start date: 2012-05-25
Bortezomib
Start date: 2012-03-30
Bortezomib
Indication: Mantle Cell Lymphoma
Start date: 2012-03-02
Bortezomib
Start date: 2012-04-27
End date: 2012-05-04
Dexamethasone
Dosage: uid/qd
Start date: 2012-04-28
End date: 2012-04-28
Dexamethasone
Start date: 2012-05-25
Dexamethasone
Indication: Mantle Cell Lymphoma
Start date: 2012-03-02
Dexamethasone
Start date: 2012-03-30
Rituximab
Dosage: uid/qd
Start date: 2012-04-27
End date: 2012-04-27
Rituximab
Indication: Mantle Cell Lymphoma
Start date: 2012-05-02
Rituximab
Start date: 2012-03-30
Rituximab
Start date: 2012-05-25
Treanda
Start date: 2012-05-25
Treanda
Indication: Mantle Cell Lymphoma
Start date: 2012-03-02
Treanda
Dosage: uid/qd
Start date: 2012-04-27
End date: 2012-04-28
Treanda
Start date: 2012-03-30
Other drugs received by patient: Valacyclovir Hydrochloride; Lederfoldine; Previscan
Possible Treanda side effects in
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-13
Patient:
Reactions: Thrombosis
Drug(s) suspected as cause:
Treanda
Possible Treanda side effects in
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-13
Patient:
Reactions: Hypercalcaemia
Drug(s) suspected as cause:
Treanda
Possible Treanda side effects in male
Reported by a physician from Germany on 2012-08-13
Patient: male, weighing 80.8 kg (177.8 pounds)
Reactions: Drug Eruption, Systemic Inflammatory Response Syndrome, Pyrexia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Treanda
Other drugs received by patient: Diovan; Rituximab; Aspirin; Bisoprolol
Possible Treanda side effects in 70 year old male
Reported by a pharmacist from United States on 2012-08-13
Patient: 70 year old male
Reactions: Histiocytosis Haematophagic, Bacteraemia, Pancytopenia, Aspergillosis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Rituximab
Treanda
Indication: Lymphoma
Start date: 2012-05-14
End date: 2012-05-15
Possible Treanda side effects in male
Reported by a physician from Italy on 2012-08-13
Patient: male
Reactions: Pyrexia, Epistaxis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cytarabine
Dosage: 500 mg/m2, cyclic
Indication: Mantle Cell Lymphoma
Start date: 2012-06-25
Rituximab
Dosage: 375 mg/m2, cyclic
Indication: Mantle Cell Lymphoma
Start date: 2012-06-25
Treanda
Dosage: 70 mg/m2, cyclic
Indication: Mantle Cell Lymphoma
Start date: 2012-06-26
Other drugs received by patient: Fluconazole; Allopurinol; Tetracosactide; Sulfamethoxazole and Trimethoprim; Darbepoetin Alfa; Pegfilgastrim; Amoxicillin and Clavulanate Potassium
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