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Taxotere (Docetaxel) - Neutropenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Neutropenia (53)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Taxotere (Docetaxel) where reactions include neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 53   Next >>

Possible Taxotere side effects in

Reported by a individual with unspecified qualification from United States on 2012-08-03

Patient: , weighing 108.4 kg (238.5 pounds)

Reactions: Febrile Neutropenia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Leuprolide Acetate
    Dosage: 22.5 mg

Taxotere
    Dosage: 174 mg



Possible Taxotere side effects in 58 year old female

Reported by a physician from Taiwan, Province of China on 2012-07-24

Patient: 58 year old female, weighing 57.3 kg (126.1 pounds)

Reactions: Multi-Organ Failure, Pneumonia, Coagulopathy, Central Nervous System Lesion, Acute Respiratory Distress Syndrome, Neutropenia, Acute Respiratory Failure, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Epirubicin
    Start date: 2010-12-28
    End date: 2010-12-28

Taxotere
    Indication: Breast Cancer
    Start date: 2010-09-30
    End date: 2010-09-30

Taxotere
    Start date: 2010-12-28
    End date: 2010-12-28

Epirubicin
    Indication: Breast Cancer
    Start date: 2010-09-30
    End date: 2010-09-30

Other drugs received by patient: Granocyte



Possible Taxotere side effects in 44 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-20

Patient: 44 year old female, weighing 55.5 kg (122.1 pounds)

Reactions: Abdominal Pain, Intestinal Ischaemia, Colitis Ischaemic, White Blood Cell Count Decreased, Vomiting, Blood Creatine Phosphokinase Increased, Gastrointestinal Necrosis, Pyrexia, Multi-Organ Failure, Diarrhoea, GAS Gangrene, Heart Rate Increased, Bone Marrow Failure, Neutropenia, Clostridial Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 7 cycles, total 4 courses
    Indication: Breast Cancer
    Start date: 2011-07-22
    End date: 2011-09-22

Epirubicin
    Dosage: 7 cycles, total 4 courses
    Indication: Breast Cancer
    Start date: 2011-07-22
    End date: 2011-09-22

Taxotere
    Dosage: 4 cycles, total 3 courses, dose taken once daily
    Indication: Breast Cancer
    Start date: 2011-10-14
    End date: 2011-11-25

Other drugs received by patient: Leucon; Lorazepam; Decadron Phosphate; Lorazepam; Kytril; Prochlorperazine; Kytril; Cepharanthin; Decadron Phosphate; Marzulene S



Possible Taxotere side effects in female

Reported by a physician from Belgium on 2012-07-19

Patient: female, weighing 66.0 kg (145.2 pounds)

Reactions: Tonsillitis, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Taxotere
    Dosage: 100mg cyclic
    Indication: Breast Cancer
    Start date: 2012-06-06

Herceptin
    Dosage: 130mg cyclic
    Indication: Breast Cancer
    Start date: 2012-06-06

Lapatinib
    Dosage: 1000mg per day
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-06-06



Possible Taxotere side effects in 64 year old female

Reported by a physician from France on 2012-07-16

Patient: 64 year old female, weighing 54.0 kg (118.8 pounds)

Reactions: Muscle Atrophy, Neutropenia, Polyarthritis, Thrombocytopenia, Paraesthesia

Drug(s) suspected as cause:
Taxotere
    Dosage: dose: 4 cycles at 120 mg every 3 weeks
    Indication: Bronchial Carcinoma
    Start date: 2011-03-28
    End date: 2011-06-03

Carboplatin
    Indication: Bronchial Carcinoma
    End date: 2011-06-01



Possible Taxotere side effects in 77 year old male

Reported by a physician from Japan on 2012-07-05

Patient: 77 year old male, weighing 67.0 kg (147.3 pounds)

Reactions: White Blood Cell Count Decreased, Gastrointestinal Haemorrhage, Pyrexia, Blood Bilirubin Decreased, Hepatic Encephalopathy, Depressed Level of Consciousness, Platelet Count Decreased, Neutropenia, Blood Pressure Decreased, Melaena

Adverse event resulted in: death

Drug(s) suspected as cause:
Taxotere
    Dosage: dose: 70mg/m2/day
    Indication: Prostate Cancer Recurrent
    Start date: 2012-05-22
    End date: 2012-05-22

Prednisolone Sodium Succinate INJ
    Indication: Prostate Cancer Recurrent
    Start date: 2012-05-22
    End date: 2012-05-30



Possible Taxotere side effects in 51 year old male

Reported by a physician from Romania on 2012-06-22

Patient: 51 year old male, weighing 76.0 kg (167.2 pounds)

Reactions: General Physical Condition Abnormal, Dehydration, Hypotension, Neutropenia, Thrombocytopenia, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Indication: Chemotherapy
    Start date: 2012-04-06
    End date: 2012-04-10

Taxotere
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09

Neulasta
    Indication: Prophylaxis
    Start date: 2012-04-12

Cisplatin
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09

Other drugs received by patient: Hydroxyurea



Possible Taxotere side effects in male

Reported by a physician from United States on 2012-06-13

Patient: male, weighing 94.8 kg (208.6 pounds)

Reactions: White Blood Cell Count Decreased, Fatigue, Dehydration, Neutropenia, Odynophagia, Rash Pruritic

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bevacizumab 15 MG / KG
    Dosage: 1425 mg ivpb
    Indication: Prostate Cancer
    Start date: 2012-06-01

Taxotere
    Dosage: 160 mg ivpb
    Indication: Prostate Cancer
    Start date: 2012-06-01

Rad001 2.5 MG
    Dosage: rad001 2.5 mg po
    Administration route: Oral
    Indication: Prostate Cancer
    Start date: 2012-06-02
    End date: 2012-06-09

Other drugs received by patient: Ramipril; Aspirin; Vicodin; Compazine; Zofran; Metformin HCL; Lupron; Ibuprofen (Advil); Xgeva; Decadron; MMX Solution



Possible Taxotere side effects in female

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-06-11

Patient: female

Reactions: Skin Disorder, Myalgia, Fatigue, Malaise, Neoplasm Malignant, Arthralgia, Metastases To Skin, Neutropenia, Leukopenia, Cough

Drug(s) suspected as cause:
Tarceva
    Dosage: unk
    Administration route: Oral
    Indication: non-Small Cell Lung Cancer Metastatic
    Start date: 2012-02-15
    End date: 2012-04-11

Taxotere
    Dosage: unk
    Indication: non-Small Cell Lung Cancer Metastatic
    Start date: 2012-04-19



Possible Taxotere side effects in female

Reported by a individual with unspecified qualification from United States on 2012-06-05

Patient: female

Reactions: Hypotension, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Taxotere
    Indication: Breast Cancer

Trastuzumab
    Indication: Breast Cancer

Carboplatin
    Indication: Breast Cancer



Possible Taxotere side effects in female

Reported by a individual with unspecified qualification from United States on 2012-06-01

Patient: female, weighing 85.2 kg (187.4 pounds)

Reactions: Neutropenia, Deep Vein Thrombosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: 140 mg
    End date: 2012-05-17

Taxotere
    Dosage: 140 mg
    End date: 2012-05-17



Possible Taxotere side effects in 51 year old male

Reported by a physician from Romania on 2012-05-31

Patient: 51 year old male, weighing 76.0 kg (167.2 pounds)

Reactions: General Physical Condition Abnormal, Dehydration, Hypotension, Neutropenia, Thrombocytopenia, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Neulasta
    Indication: Prophylaxis
    Start date: 2012-04-12

Cisplatin
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09

Fluorouracil
    Indication: Chemotherapy
    Start date: 2012-04-06
    End date: 2012-04-10

Taxotere
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09



Possible Taxotere side effects in 51 year old male

Reported by a physician from Romania on 2012-05-29

Patient: 51 year old male, weighing 76.0 kg (167.2 pounds)

Reactions: General Physical Condition Abnormal, Diarrhoea, Dehydration, Hypotension, Neutropenia, Thrombocytopenia, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 750 mg/m2, per chemo regim
    Indication: Chemotherapy
    Start date: 2012-04-06
    End date: 2012-04-10

Taxotere
    Dosage: 75 mg/m2, per chemo regim
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09

Cisplatin
    Dosage: 75 mg/m2, per chemo regim
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09

Neulasta
    Dosage: 6 mg, after chemo
    Indication: Prophylaxis
    Start date: 2012-04-12

Other drugs received by patient: Hidrea



Possible Taxotere side effects in 68 year old male

Reported by a physician from United States on 2012-05-29

Patient: 68 year old male, weighing 109.6 kg (241.1 pounds)

Reactions: Fatigue, Hypocalcaemia, Neutropenia, Asthenia, Paraesthesia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Taxotere
    Indication: Prostate Cancer Metastatic
    Start date: 2012-01-19
    End date: 2012-01-19

Blinded Therapy
    Dosage: last dose given on cycle 2 day 25
    Administration route: Oral
    Indication: Prostate Cancer Metastatic
    Start date: 2011-11-07
    End date: 2011-12-29

Denosumab
    Indication: Prostate Cancer Metastatic
    Start date: 2011-11-07
    End date: 2011-12-05

Prednisone TAB
    Dosage: 28 day cycles
    Administration route: Oral
    Indication: Prostate Cancer Metastatic
    Start date: 2011-11-07
    End date: 2012-01-15

Other drugs received by patient: Vitamin D; Calcium



Possible Taxotere side effects in female

Reported by a physician from United States on 2012-05-24

Patient: female, weighing 68.4 kg (150.5 pounds)

Reactions: Productive Cough, Hypokalaemia, Blood Calcium Decreased, Pleural Effusion, Hypoxia, Acute Respiratory Failure, Blood Creatinine Increased, Fluid Overload, White Blood Cell Count Decreased, Pneumonia, Hypotension, Hyponatraemia, Pulmonary Fibrosis, Dehydration, Neutropenia, Asthenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Taxotere
    Dosage: 532 mg
    End date: 2011-10-25

Cisplatin
    Dosage: 532 mg
    End date: 2011-10-25



Possible Taxotere side effects in female

Reported by a physician from United States on 2012-05-18

Patient: female, weighing 68.4 kg (150.5 pounds)

Reactions: Productive Cough, White Blood Cell Count Decreased, Fluid Overload, Hypotension, Hyponatraemia, Pulmonary Fibrosis, Hypokalaemia, Blood Calcium Decreased, Respiratory Failure, Dehydration, Pleural Effusion, Neutropenia, Blood Creatinine Increased, Asthenia, Pneumonitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: 532 mg
    End date: 2011-10-25

Taxotere
    Dosage: 532 mg
    End date: 2011-10-25



Possible Taxotere side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-05-08

Patient: 70 year old male

Reactions: Glossodynia, Chills, Pyrexia, Pulmonary Sepsis, Diarrhoea, Febrile Bone Marrow Aplasia, Systemic Inflammatory Response Syndrome, Abdominal Distension, Neutropenia, Pharyngeal Erythema, Cough, Hepatic Cirrhosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Start date: 2011-02-25
    End date: 2011-02-27

Taxotere
    Start date: 2011-02-07

Eloxatin
    Start date: 2011-02-07

Fluorouracil
    Start date: 2011-02-07

Eloxatin
    Start date: 2011-02-25
    End date: 2011-02-27

Taxotere
    Start date: 2011-02-25
    End date: 2011-02-27



Possible Taxotere side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-05-08

Patient: 70 year old male

Reactions: Glossodynia, Chills, Pyrexia, Pulmonary Sepsis, Diarrhoea, Febrile Bone Marrow Aplasia, Abdominal Distension, Systemic Inflammatory Response Syndrome, Neutropenia, Pharyngeal Erythema, Hepatic Cirrhosis, Cough

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Taxotere
    Start date: 2011-02-07

Eloxatin
    Start date: 2011-02-07

Fluorouracil
    Start date: 2011-02-07

Eloxatin
    Start date: 2011-02-25
    End date: 2011-02-27

Fluorouracil
    Start date: 2011-02-25
    End date: 2011-02-27

Taxotere
    Start date: 2011-02-25
    End date: 2011-02-27



Possible Taxotere side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-05-04

Patient: female

Reactions: Diarrhoea, Conjunctivitis, Palmar-Plantar Erythrodysaesthesia Syndrome, Neutropenia, Onycholysis, Rash, Mucous Membrane Disorder, Toxic Skin Eruption

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Breast Cancer
    Start date: 2012-01-20
    End date: 2012-01-20

Taxotere
    Indication: Breast Cancer
    Start date: 2012-01-20
    End date: 2012-01-20



Possible Taxotere side effects in 51 year old male

Reported by a physician from Romania on 2012-04-30

Patient: 51 year old male, weighing 76.0 kg (167.2 pounds)

Reactions: General Physical Condition Abnormal, Diarrhoea, Dehydration, Hypotension, Neutropenia, Thrombocytopenia, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 750 mg/m2, per chemo regim
    Indication: Chemotherapy
    Start date: 2012-04-06
    End date: 2012-04-10

Neulasta
    Dosage: 6 mg, after chemo
    Indication: Prophylaxis
    Start date: 2012-04-12

Cisplatin
    Dosage: 75 mg/m2, per chemo regim
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09

Taxotere
    Dosage: 75 mg/m2, per chemo regim
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09



Possible Taxotere side effects in female

Reported by a consumer/non-health professional from France on 2012-04-24

Patient: female

Reactions: Diarrhoea, Neutropenia

Drug(s) suspected as cause:
Taxotere
    Dosage: 3rd cycle on 16mar2011
    Indication: Breast Cancer
    Start date: 2011-01-01
    End date: 2011-03-16

Carboplatin

Herceptin



Possible Taxotere side effects in 60 year old male

Reported by a physician from United States on 2012-04-24

Patient: 60 year old male

Reactions: Febrile Neutropenia, Neutropenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Fluorouracil

Carboplatin

Taxotere

Neulastim
    Indication: Prophylaxis



Possible Taxotere side effects in 64 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-13

Patient: 64 year old female, weighing 83.4 kg (183.5 pounds)

Reactions: Fracture, Wound, Palmar-Plantar Erythrodysaesthesia Syndrome, Neutropenia, Rash, Fall

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Taxotere
    Dosage: every 3 weeks
    Start date: 2012-02-01
    End date: 2012-02-01

Xeloda
    Start date: 2012-01-11
    End date: 2012-01-18

Taxotere
    Dosage: every 3 weeks
    Start date: 2012-01-11
    End date: 2012-01-11

Other drugs received by patient: Dexamethasone



Possible Taxotere side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-04-10

Patient: male

Reactions: Neutropenia

Drug(s) suspected as cause:
Taxotere
    Indication: Prostate Cancer Metastatic

Goserelin
    Indication: Prostate Cancer Metastatic



Possible Taxotere side effects in 50 year old female

Reported by a physician from Italy on 2012-04-06

Patient: 50 year old female

Reactions: Vaginal Inflammation, Stomatitis, Urticaria, Neutropenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Xeloda
    Dosage: 3500 mg, unk
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-12-22
    End date: 2012-01-04

Taxotere
    Dosage: 100 mg, qwk
    Indication: Breast Cancer
    Start date: 2011-12-22
    End date: 2011-12-22

Granulokine
    Dosage: 1 df, unk
    Indication: Prophylaxis
    Start date: 2012-01-03
    End date: 2012-01-04

Other drugs received by patient: Levothyroxine Sodium; Esomeprazolo DOC Generici



Possible Taxotere side effects in 65 year old male

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-04-06

Patient: 65 year old male

Reactions: Diarrhoea, Neutropenia, Pyrexia, Depressed Mood, Tremor

Adverse event resulted in: death

Drug(s) suspected as cause:
Taxotere



Possible Taxotere side effects in male

Reported by a physician from United States on 2012-04-05

Patient: male, weighing 57.6 kg (126.7 pounds)

Reactions: Hypotension, Device Dislocation, Fatigue, Malaise, Dehydration, Neutropenia, Thrombocytopenia, Asthenia, Clostridial Infection, Muscle Spasms

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 487 mgg
    End date: 2012-02-29

Taxotere
    Dosage: 126 mg
    End date: 2012-02-29



Possible Taxotere side effects in 56 year old male

Reported by a physician from Japan on 2012-04-04

Patient: 56 year old male, weighing 58.3 kg (128.3 pounds)

Reactions: Anaemia, Oedema, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Taxotere
    Dosage: 40-50mg 1 timetwo weeks
    Indication: Gastric Cancer Stage IV
    Start date: 2011-11-29
    End date: 2012-01-10

Cisplatin
    Dosage: dose and frequency: 20-50mg times for 1 week
    Indication: Gastric Cancer Stage IV
    Start date: 2011-11-29
    End date: 2012-01-10

TS-1
    Dosage: route: internal
    Start date: 2011-12-27
    End date: 2012-01-09

Paclitaxel
    Indication: Gastric Cancer Stage IV
    Start date: 2011-04-19
    End date: 2011-06-07

TS-1
    Dosage: route: internalfrequency: 60 mgx2 times
    Indication: Gastric Cancer Stage IV
    Start date: 2011-11-29
    End date: 2011-12-12

Cisplatin
    Dosage: frequency: 1 time/ 5 weeks
    Indication: Gastric Cancer Stage IV
    Start date: 2011-08-31
    End date: 2011-11-29

Other drugs received by patient: Citric Acid and Sodium Citrate and Sodium Phosphate Monobasic (Anhydra; Citric Acid and Sodium Citrate and Sodium Phosphate Monobasic (Anhydra



Possible Taxotere side effects in female

Reported by a physician from Italy on 2012-04-04

Patient: female

Reactions: Stomatitis, Vaginal Inflammation, Urticaria, Neutropenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Taxotere
    Indication: Breast Cancer Female
    Start date: 2011-12-22
    End date: 2011-12-22

Xeloda
    Administration route: Oral
    Indication: Breast Cancer Female
    Start date: 2011-12-22
    End date: 2012-01-04

Granulokine
    Indication: Colony Stimulating Factor Prophylaxis
    Start date: 2012-01-03
    End date: 2012-01-04

Other drugs received by patient: Levothyroxine Sodium; Esomeprazole



Possible Taxotere side effects in 55 year old male

Reported by a physician from Japan on 2012-03-22

Patient: 55 year old male, weighing 58.3 kg (128.3 pounds)

Reactions: Anaemia, Neoplasm Progression, Gastric Cancer Stage IV, Toxicity To Various Agents, Haematotoxicity, Bone Marrow Disorder, Malignant Ascites, Oedema, Neutropenia, Malignant Peritoneal Neoplasm, Thrombocytopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Taxotere
    Dosage: 40-50mg 1 timetwo weeks
    Indication: Gastric Cancer Stage IV
    Start date: 2011-11-29
    End date: 2012-01-10

Cisplatin
    Dosage: frequency: 1 time/ 5 weeks
    Indication: Gastric Cancer Stage IV
    Start date: 2011-08-31
    End date: 2011-11-29

TS-1
    Dosage: route: internal
    Start date: 2011-12-27
    End date: 2012-01-09

Cisplatin
    Dosage: dose and frequency: 20-50mg times for 1 week
    Indication: Gastric Cancer Stage IV
    Start date: 2011-11-29
    End date: 2012-01-10

TS-1
    Dosage: route: internalfrequency: 60 mgx2 times
    Indication: Gastric Cancer Stage IV
    Start date: 2011-11-29
    End date: 2011-12-12

Paclitaxel
    Indication: Gastric Cancer Stage IV
    Start date: 2011-04-19
    End date: 2011-06-07

Other drugs received by patient: Citric Acid and Sodium Citrate and Sodium Phosphate Monobasic (Anhydra; Citric Acid and Sodium Citrate and Sodium Phosphate Monobasic (Anhydra



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