This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Taxotere (Docetaxel) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (655)
Death (177)
Life Threatening Events (48)
Disability (63)
Reports by Reaction Type
Interstitial Lung Disease (58),
Dyspnoea (56),
Neutropenia (53),
Pyrexia (50),
Diarrhoea (49),
Nausea (37),
Febrile Neutropenia (36),
Dehydration (33),
Death (31),
Hypotension (30),
Pneumonia (29),
Thrombocytopenia (27)
Below are a few examples of reports where side effects / adverse reactions may be related to Taxotere (Docetaxel). For a complete list or a specific selection of reports, please use the links above.
Possible Taxotere side effects in 49 year old female
Reported by a consumer/non-health professional from France on 2012-08-27
Patient: 49 year old female
Reactions: Chills, Skin Burning Sensation, LIP Oedema, Erythema, Paraesthesia, Neuropathy Peripheral, Hot Flush, Arthralgia, Oral Candidiasis, Visual Impairment
Drug(s) suspected as cause:
Taxotere
Start date: 2012-07-05
Taxotere
Indication: Breast Operation
Start date: 2012-05-25
Other drugs received by patient: Prednisolone; Tridesonit; Pyostacine; Acetaminophen; Trastuzumab; Prednisolone; Amitriptyline Hydrochloride
Possible Taxotere side effects in 72 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-27
Patient: 72 year old female
Reactions: Acute Respiratory Distress Syndrome
Adverse event resulted in: death
Drug(s) suspected as cause:
Taxotere
Start date: 2012-05-18
End date: 2012-05-18
Taxotere
Start date: 2012-04-24
End date: 2012-04-24
Taxotere
Start date: 2012-06-08
End date: 2012-06-08
Other drugs received by patient: Zometa; Neulasta; Duragesic-100; Corticosteroids; Acetaminophen; Vitamin D; Fentanyl; Avibon; Tramadol HCL
Possible Taxotere side effects in 70 year old male
Reported by a physician from Canada on 2012-08-24
Patient: 70 year old male, weighing 51.6 kg (113.5 pounds)
Reactions: Disease Progression
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Blinded Therapy
Dosage: received every three weeks (day 1 of 21 day cycle)
Indication: non-Small Cell Lung Cancer Stage IV
Start date: 2012-05-11
End date: 2012-05-11
Taxotere
Dosage: received every three weeks (day 1 of 21 day cycle)
Indication: non-Small Cell Lung Cancer Stage IV
Start date: 2012-05-11
End date: 2012-05-11
Other drugs received by patient: Bisoprolol Fumarate; Methadone Hydrochloride; Polyethylene Glycol; Hydromorphone HCL; Senokot / UNK /; Hydromorphone Hydrochloride; Vitamin D
Possible Taxotere side effects in female
Reported by a individual with unspecified qualification from United States on 2012-08-24
Patient: female, weighing 101.6 kg (223.5 pounds)
Reactions: Dehydration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cisplatin
Dosage: 150 mg
End date: 2012-08-20
Taxotere
Dosage: 150 mg
End date: 2012-08-20
Possible Taxotere side effects in 75 year old male
Reported by a physician from Japan on 2012-08-23
Patient: 75 year old male, weighing 65.0 kg (143.0 pounds)
Reactions: Interstitial Lung Disease, Hypoxia, Rash, Pyrexia
Adverse event resulted in: death
Drug(s) suspected as cause:
Garenoxacin Mesylate
Administration route: Oral
Indication: Pyrexia
Start date: 2012-06-12
Taxotere
Start date: 2012-04-05
Other drugs received by patient: Micardis; Calblock
Possible Taxotere side effects in female
Reported by a consumer/non-health professional from Canada on 2012-08-23
Patient: female
Reactions: Weight Increased, Disease Progression
Drug(s) suspected as cause:
Exemestane
Indication: Product Used FOR Unknown Indication
Letrozole
Administration route: Oral
Indication: Breast Cancer
Taxotere
Indication: Breast Cancer
Xeloda
Indication: Breast Cancer
Possible Taxotere side effects in 44 year old female
Reported by a physician from Germany on 2012-08-23
Patient: 44 year old female, weighing 72.0 kg (158.4 pounds)
Reactions: Venous Thrombosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: 1110 mg, q3wk
Indication: Breast Cancer
Start date: 2010-08-03
End date: 2010-10-05
Neulasta
Dosage: 6 mg, qd
Indication: Colony Stimulating Factor Prophylaxis
Start date: 2010-10-06
Taxotere
Dosage: 138.75 mg, q3wk
Indication: Breast Cancer
Start date: 2010-08-03
End date: 2010-10-05
Other drugs received by patient: Dexamethasone Sodium Phosphate; Dexamethasone Sodium Phosphate; Palonosetron; Mesna; Bromocriptin; Dexamethasone Sodium Phosphate; Mesna
Possible Taxotere side effects in 66 year old male
Reported by a physician from Japan on 2012-08-23
Patient: 66 year old male, weighing 66.0 kg (145.2 pounds)
Reactions: Visual Field Defect, Visual Acuity Reduced, Blindness Unilateral, Optic Neuritis, Optic Ischaemic Neuropathy, Septic Shock, Pneumonia Pneumococcal
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Taxotere
Other drugs received by patient: Dexamethasone; Estracyt
Possible Taxotere side effects in 83 year old male
Reported by a consumer/non-health professional from Japan on 2012-08-20
Patient: 83 year old male
Reactions: Death, Alopecia, Nail Disorder
Adverse event resulted in: death
Drug(s) suspected as cause:
Taxotere
Possible Taxotere side effects in 77 year old male
Reported by a physician from China on 2012-08-17
Patient: 77 year old male, weighing 58.0 kg (127.6 pounds)
Reactions: Multi-Organ Failure
Adverse event resulted in: death
Drug(s) suspected as cause:
Taxotere
Other drugs received by patient: Sulbenicillin; Ambroxol; Prednisone TAB; Dexamethasone; Insulin; Dexamethasone
Possible Taxotere side effects in 69 year old female
Reported by a physician from Japan on 2012-08-17
Patient: 69 year old female, weighing 42.0 kg (92.4 pounds)
Reactions: Respiratory Failure, Depressed Level of Consciousness, Hypoxia
Adverse event resulted in: death
Drug(s) suspected as cause:
Taxotere
Other drugs received by patient: Trastuzumab
Possible Taxotere side effects in 72 year old female
Reported by a physician from Japan on 2012-08-17
Patient: 72 year old female
Reactions: Malaise, Alopecia, Decreased Appetite
Drug(s) suspected as cause:
Taxotere
Dosage: on day one
Indication: Gastric Cancer
Start date: 2010-04-05
End date: 2010-08-16
TS-1
Dosage: on days 1-14, every three weeks
Administration route: Oral
Indication: Gastric Cancer
Start date: 2010-04-05
End date: 2010-08-16
Possible Taxotere side effects in male
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-15
Patient: male
Reactions: Pseudomonas Infection, Febrile Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Tarceva
Dosage: 150 mg, uid/qd
Administration route: Oral
Indication: Lung Cancer Metastatic
Start date: 2011-05-10
End date: 2012-08-07
Taxotere
Dosage: 140 mg, daily, cyclic
Indication: Lung Cancer Metastatic
Start date: 2012-07-20
End date: 2012-07-20
Possible Taxotere side effects in 44 year old female
Reported by a pharmacist from Germany on 2012-08-15
Patient: 44 year old female, weighing 64.0 kg (140.8 pounds)
Reactions: Paraparesis, Pain
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Taxotere
Other drugs received by patient: Dexamethasone
Possible Taxotere side effects in male
Reported by a physician from United Kingdom on 2012-08-14
Patient: male
Reactions: Sepsis, Hepatorenal Failure
Adverse event resulted in: death
Drug(s) suspected as cause:
Taxotere
Possible Taxotere side effects in male
Reported by a individual with unspecified qualification from United States on 2012-08-14
Patient: male, weighing 60.8 kg (133.7 pounds)
Reactions: Cellulitis, Inflammation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Carboplatin
Dosage: 580 mg
Start date: 2012-07-09
End date: 2012-07-30
Taxotere
Dosage: 130 mg
Start date: 2012-07-09
End date: 2012-07-30
Possible Taxotere side effects in 80 year old male
Reported by a physician from Japan on 2012-08-13
Patient: 80 year old male
Reactions: Interstitial Lung Disease, Rales, Mycoplasma Test Positive, Cough
Drug(s) suspected as cause:
Taxotere
Dosage: unk ukn, unk
Start date: 2012-04-18
Zometa
Dosage: 4 mg, unk
Indication: Metastases To Bone
Start date: 2012-04-18
Possible Taxotere side effects in 66 year old male
Reported by a physician from Japan on 2012-08-13
Patient: 66 year old male, weighing 66.0 kg (145.2 pounds)
Reactions: Visual Field Defect, Blindness Unilateral, Visual Acuity Reduced, Optic Ischaemic Neuropathy, Optic Neuritis, Septic Shock, Pneumonia Pneumococcal
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Taxotere
Other drugs received by patient: Dexamethasone; Estracyt
Possible Taxotere side effects in 53 year old female
Reported by a physician from Japan on 2012-08-13
Patient: 53 year old female
Reactions: Neuropathy Peripheral, Activities of Daily Living Impaired, Visual Acuity Reduced
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Capecitabine
Start date: 2011-02-28
End date: 2011-04-01
Paclitaxel
Dosage: 9 courses administered
Start date: 2011-04-25
End date: 2011-11-09
Taxotere
Start date: 2011-02-28
End date: 2011-04-01
Possible Taxotere side effects in 41 year old female
Reported by a physician from Algeria on 2012-08-09
Patient: 41 year old female
Reactions: Dyspnoea Exertional
Adverse event resulted in: death
Drug(s) suspected as cause:
Taxotere
Possible Taxotere side effects in female
Reported by a physician from Japan on 2012-08-08
Patient: female, weighing 52.0 kg (114.4 pounds)
Reactions: Interstitial Lung Disease, Cardiac Failure, Cerebral Infarction, Disseminated Intravascular Coagulation
Adverse event resulted in: death
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: doseage is uncertain
Indication: Breast Cancer
Start date: 2010-02-05
End date: 2010-04-09
Herceptin
Dosage: dose lowered
Start date: 2010-07-09
End date: 2010-07-09
Herceptin
Start date: 2010-05-28
End date: 2010-05-28
Herceptin
Start date: 2010-06-18
End date: 2010-06-18
Herceptin
Indication: Breast Cancer
Start date: 2010-05-07
End date: 2010-05-07
Taxotere
Dosage: dose is uncertain
Indication: Breast Cancer
Start date: 2010-05-07
End date: 2010-07-09
Other drugs received by patient: Fluorouracil; Epirubicin Hydrochloride; Betamethasone; Sulpiride; Sulpiride; Prochlorperazine; Betamethasone; Prochlorperazine; Sulpiride; Betamethasone; Sulpiride; Prochlorperazine; Betamethasone; Prochlorperazine
Possible Taxotere side effects in female
Reported by a physician from United States on 2012-08-07
Patient: female, weighing 69.9 kg (153.8 pounds)
Reactions: Urinary Tract Infection, Bacterial Sepsis, Abscess, Peritonitis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Carboplatin
Dosage: 792 mg
End date: 2011-08-10
Herceptin
Dosage: 140 mg
End date: 2011-08-10
Taxotere
Dosage: 130 mg
End date: 2011-08-10
Possible Taxotere side effects in 60 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-06
Patient: 60 year old male
Reactions: Dysphagia, Fluid Intake Reduced, Oesophageal Stenosis
Drug(s) suspected as cause:
Cisplatin
Dosage: (6 mg/m2)
Indication: Gastric Cancer Stage I
Start date: 2010-10-01
Cisplatin
Dosage: (6 mg/m2)
Indication: Oesophageal Squamous Cell Carcinoma Stage III
Start date: 2010-10-01
Fluorouracil
Dosage: (350 mg/m2)
Indication: Oesophageal Squamous Cell Carcinoma Stage II
Start date: 2010-10-01
Fluorouracil
Dosage: (350 mg/m2)
Indication: Gastric Cancer Stage I
Start date: 2010-10-01
Taxotere
Dosage: (60 mg/m2; every three weeks)
Indication: Oesophageal Squamous Cell Carcinoma Stage II
Start date: 2010-10-01
Taxotere
Dosage: (60 mg/m2; every three weeks)
Indication: Gastric Cancer Stage I
Start date: 2010-10-01
Therapeutic Radiopharmaceuticals (Therapeutic Radiopharmaceuticals)
Dosage: (60 gy)
Indication: Oesophageal Squamous Cell Carcinoma Stage II
Start date: 2010-10-01
Therapeutic Radiopharmaceuticals (Therapeutic Radiopharmaceuticals)
Dosage: (60 gy)
Indication: Gastric Cancer Stage I
Start date: 2010-10-01
Possible Taxotere side effects in 64 year old male
Reported by a physician from Japan on 2012-08-03
Patient: 64 year old male, weighing 61.1 kg (134.5 pounds)
Reactions: Conjunctival Oedema, Visual Acuity Reduced, Macular Oedema
Drug(s) suspected as cause:
Taxotere
Dosage: every 4 weeks
Start date: 2010-03-05
End date: 2012-04-01
Taxotere
Dosage: frequency: every 4 weeks.
Start date: 2012-06-04
Other drugs received by patient: Leuprolide Acetate; Dexamethasone; Zometa; Estracyt
Possible Taxotere side effects in
Reported by a individual with unspecified qualification from United States on 2012-08-03
Patient: , weighing 108.4 kg (238.5 pounds)
Reactions: Febrile Neutropenia, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Leuprolide Acetate
Dosage: 22.5 mg
Taxotere
Dosage: 174 mg
Possible Taxotere side effects in 77 year old male
Reported by a physician from United States on 2012-08-03
Patient: 77 year old male, weighing 73.0 kg (160.6 pounds)
Reactions: Pulmonary Haemorrhage, Fatigue, Rash
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Simvastatin
Indication: non-Small Cell Lung Cancer Stage IV
Start date: 2012-06-07
End date: 2012-07-19
Taxotere
Start date: 2012-07-19
End date: 2012-07-19
Taxotere
Indication: non-Small Cell Lung Cancer Stage IV
Start date: 2012-06-07
End date: 2012-06-07
Possible Taxotere side effects in 71 year old female
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-08-02
Patient: 71 year old female, weighing 74.0 kg (162.8 pounds)
Reactions: Fatigue
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: 1020 mg, q3wk
Indication: Breast Cancer
Start date: 2009-12-09
End date: 2010-01-27
Neulasta
Dosage: 6 mg, q3wk
Indication: Premedication
Start date: 2009-12-09
End date: 2010-01-27
Neulasta
Indication: Colony Stimulating Factor Prophylaxis
Taxotere
Dosage: 128 mg, q3wk
Indication: Breast Cancer
Start date: 2009-12-09
End date: 2010-01-27
Other drugs received by patient: Dexamethasone; Aloxi; Mesna; Dexamethasone
Possible Taxotere side effects in 80 year old male
Reported by a physician from Japan on 2012-08-02
Patient: 80 year old male
Reactions: Staphylococcal Infection, Disseminated Intravascular Coagulation, Febrile Neutropenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Taxotere
Other drugs received by patient: Therapeutic Radiopharmaceuticals; Decadron
Possible Taxotere side effects in 70 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-01
Patient: 70 year old female, weighing 71.0 kg (156.2 pounds)
Reactions: Stomatitis, Radiation Injury, Oral Pain, Odynophagia, Thermal Burn
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dermoplast
Erbitux
Dosage: 1st course:30-mar-2005. week 1 loading dose400 mg/m2. weeks 2-7, weekly 250 mg/m2. totaldose:435mg
Indication: Head and Neck Cancer
Start date: 2005-05-10
End date: 2005-05-10
Taxotere
Dosage: 1st course docetaxel 30-mar-2005. weeks 2-7 docetaxel weekly 15 mg/m2. total dose:26.1mg
Indication: Head and Neck Cancer
Start date: 2005-05-10
End date: 2005-05-10
Other drugs received by patient: Colace; Cytomel; Allegra; Atenolol; Morphine Sulfate; Levaquin; Celebrex
Possible Taxotere side effects in male
Reported by a physician from Japan on 2012-07-31
Patient: male
Reactions: Ischaemia, Visual Field Defect, Blindness Unilateral, Optic Neuritis
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Taxotere
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