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Index of reports
> Life Threatening Events (28)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Taxol (Paclitaxel) life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Taxol side effects in 52 year old female
Reported by a consumer/non-health professional from France on 2012-08-22
Patient: 52 year old female
Reactions: Chest Wall Necrosis
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Avastin
Dosage: 1 df = 25mg/ml, concentrate for solution for infusion
Start date: 2012-02-01
End date: 2012-06-06
Taxol
Start date: 2012-02-01
End date: 2012-06-06
Possible Taxol side effects in female
Reported by a pharmacist from United States on 2012-08-16
Patient: female, weighing 41.5 kg (91.4 pounds)
Reactions: Agitation, Dyspnoea, Cardio-Respiratory Arrest, Cyanosis, Blood Pressure Immeasurable, Oxygen Saturation Decreased, Panic Reaction, Infusion Related Reaction
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
Possible Taxol side effects in male
Reported by a physician from United Kingdom on 2012-08-15
Patient: male
Reactions: Pulmonary Sepsis, Metabolic Acidosis, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
Dosage: 175 mg/m2, unk
Indication: non-Small Cell Lung Cancer Metastatic
Start date: 2012-07-26
End date: 2012-07-26
Pemetrexed
Dosage: 500 mg/m2, unk
Indication: non-Small Cell Lung Cancer Metastatic
Start date: 2012-07-26
End date: 2012-07-26
Other drugs received by patient: Dexamethasone; Vitamin B-12; Dexamethasone; Metoclopramide; Erythromycin; Folic Acid; Infumorph; Piperacillin and Tazobactam; Clarithromycin; Dexamethasone; Ramipril; Amlodipine; Dexamethasone; Omeprazole
Possible Taxol side effects in male
Reported by a physician from United Kingdom on 2012-08-14
Patient: male
Reactions: Pulmonary Sepsis, Metabolic Acidosis, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
Dosage: 175 mg/m2, unk
Indication: non-Small Cell Lung Cancer Metastatic
Start date: 2012-07-26
End date: 2012-07-26
Pemetrexed
Dosage: 500 mg/m2, unk
Indication: non-Small Cell Lung Cancer Metastatic
Start date: 2012-07-26
End date: 2012-07-26
Other drugs received by patient: Dexamethasone; Infumorph; Dexamethasone; Dexamethasone; Dexamethasone; Omeprazole; Clarithromycin; Piperacillin and Tazobactam; Erythromycin; Folic Acid; Ramipril; Amlodipine; Metoclopramide; Vitamin B-12
Possible Taxol side effects in 52 year old female
Reported by a physician from France on 2012-08-10
Patient: 52 year old female
Reactions: Chest Wall Necrosis
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Taxol
Indication: Product Used FOR Unknown Indication
Start date: 2012-02-01
End date: 2012-06-06
Avastin
Indication: Product Used FOR Unknown Indication
Start date: 2012-02-01
End date: 2012-06-06
Possible Taxol side effects in 81 year old male
Reported by a consumer/non-health professional from France on 2012-08-07
Patient: 81 year old male
Reactions: Pleural Effusion, Acute Respiratory Distress Syndrome, Drug Interaction
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
Other drugs received by patient possibly interacting with the suspect drug:
Carboplatin
Dosage: hospira
Indication: Lung Squamous Cell Carcinoma Stage Unspecified
Start date: 2012-07-06
Possible Taxol side effects in 47 year old female
Reported by a consumer/non-health professional from Czech Republic on 2012-08-07
Patient: 47 year old female, weighing 57.0 kg (125.4 pounds)
Reactions: Uterine Prolapse, Dyspnoea, Cyanosis, Bronchospasm, Loss of Consciousness
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
Other drugs received by patient: Ranital; Dithiaden; Zofran; Dexamethasone
Possible Taxol side effects in 61 year old female
Reported by a physician from United States on 2012-06-07
Patient: 61 year old female
Reactions: Acute Lymphocytic Leukaemia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Herceptin
Indication: Breast Cancer
Start date: 2000-01-01
End date: 2002-01-01
Cytoxan
Indication: Breast Cancer
Start date: 2000-01-01
Taxol
Indication: Breast Cancer
Start date: 2000-01-01
End date: 2002-01-01
Adriamycin PFS
Indication: Breast Cancer
Start date: 2000-01-01
Possible Taxol side effects in female
Reported by a individual with unspecified qualification from United States on 2012-05-17
Patient: female
Reactions: Embolism
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Nolvadex
Administration route: Oral
Indication: Breast Cancer
Start date: 2000-12-05
Taxol
Indication: Breast Cancer
Herceptin
Dosage: maintenance dose over 30 mins, for 51 weeks
Adriamycin PFS
Indication: Breast Cancer
Start date: 2000-12-05
Herceptin
Dosage: loading dose
Indication: Breast Cancer
Cytoxan
Indication: Breast Cancer
Start date: 2000-12-05
Possible Taxol side effects in 66 year old female
Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-04-24
Patient: 66 year old female, weighing 75.0 kg (165.0 pounds)
Reactions: Syncope, Hypopnoea, Urinary Incontinence, Hypotension, Bradycardia, Loss of Consciousness, Infusion Related Reaction
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Taxol
Start date: 2012-03-09
End date: 2012-03-09
Carboplatin
Start date: 2012-03-09
End date: 2012-01-01
Other drugs received by patient: Dexamethasone; Kytril; Ranitidine; Methylprednisolone; Prednisone TAB; Voluven; Atropine; Chlorphenoxamine HCL
Possible Taxol side effects in 62 year old female
Reported by a consumer/non-health professional from Turkey on 2012-04-23
Patient: 62 year old female, weighing 47.0 kg (103.4 pounds)
Reactions: Syncope
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Carboplatin
Start date: 2012-03-09
Taxol
Start date: 2012-03-09
Other drugs received by patient: Dexamethasone; Kytril; Chlorphenoxamine HCL; Ranitidine HCL
Possible Taxol side effects in 73 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-23
Patient: 73 year old male, weighing 81.0 kg (178.2 pounds)
Reactions: Fatigue, Dyspnoea, Embolism, Abdominal Pain Upper, Cough
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
Dosage: paclitaxel 200mg/m2 days 71 and 92
Indication: non-Small Cell Lung Cancer
Start date: 2010-04-05
End date: 2010-04-05
Erbitux
Dosage: cetuximab 250 mg/m2 days 50,57,64,71,78, 85,92,99,106
Indication: non-Small Cell Lung Cancer
Start date: 2010-04-12
End date: 2010-04-12
Carboplatin
Dosage: carboplatin auc=6 days 71 and 92
Indication: non-Small Cell Lung Cancer
Start date: 2010-04-05
End date: 2010-04-05
Possible Taxol side effects in female
Reported by a physician from United Kingdom on 2012-04-02
Patient: female, weighing 83.0 kg (182.6 pounds)
Reactions: Acute Respiratory Distress Syndrome, Pneumonitis
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Pemetrexed
Dosage: 500 mg/m2, unk
Indication: non-Small Cell Lung Cancer
Start date: 2011-11-04
End date: 2011-11-25
Taxol
Dosage: 175 mg/m2, unk
Indication: non-Small Cell Lung Cancer
Start date: 2011-11-04
End date: 2011-11-25
Other drugs received by patient: Dexamethasone; Folic Acid; Tinzaparin; Temazepam; Vitamin B-12
Possible Taxol side effects in 72 year old female
Reported by a physician from France on 2012-03-02
Patient: 72 year old female
Reactions: Cardiac Failure, Dehydration, Tachypnoea, Febrile Neutropenia, Asthenia, Decreased Appetite, Cough
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Gemzar
Dosage: 200mg*3
Indication: Ovarian Cancer
Taxol
Dosage: 60mg*3
Indication: Ovarian Cancer
Start date: 2004-10-04
End date: 2004-10-06
Carboplatin
Dosage: 100mg*3
Indication: Ovarian Cancer
Possible Taxol side effects in 61 year old female
Reported by a consumer/non-health professional from France on 2012-03-01
Patient: 61 year old female
Reactions: Coronary Artery Disease
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Herceptin
Indication: Breast Cancer
Start date: 2011-12-08
Taxol
Indication: Breast Cancer
Start date: 2011-12-08
Other drugs received by patient: Lyrica
Possible Taxol side effects in female
Reported by a physician from France on 2012-02-27
Patient: female
Reactions: Coronary Artery Disease
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Herceptin
Indication: Breast Cancer
Start date: 2011-12-08
Taxol
Administration route: Oral
Indication: Breast Cancer
Start date: 2011-12-08
Other drugs received by patient: Lyrica
Possible Taxol side effects in female
Reported by a physician from United Kingdom on 2012-01-23
Patient: female, weighing 83.0 kg (182.6 pounds)
Reactions: Acute Respiratory Distress Syndrome, Pneumonitis
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Pemetrexed
Dosage: 500 mg/m2, unk
Indication: non-Small Cell Lung Cancer
Start date: 2011-11-04
End date: 2011-11-25
Taxol
Dosage: 175 mg/m2, unk
Indication: non-Small Cell Lung Cancer
Start date: 2011-11-04
End date: 2011-11-25
Other drugs received by patient: Vitamin B-12; Tinzaparin; Dexamethasone TAB; Temazepam; Folic Acid
Possible Taxol side effects in 72 year old female
Reported by a physician from Japan on 2012-01-16
Patient: 72 year old female, weighing 40.0 kg (88.0 pounds)
Reactions: Gastrointestinal Perforation, Abdominal Pain Lower
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Paraplatin
Dosage: freq:other auc:6
Indication: Ovarian Cancer
Start date: 2011-08-30
End date: 2011-09-27
Taxol
Dosage: 180mg/m2:224 mg on 30aug11 stopped on 27sep11 freq:other.
Indication: Ovarian Cancer
Possible Taxol side effects in 72 year old female
Reported by a consumer/non-health professional from Japan on 2012-01-02
Patient: 72 year old female, weighing 40.0 kg (88.0 pounds)
Reactions: Abdominal Pain Lower, Gastrointestinal Perforation
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
Dosage: 180mg/m2:224 mg on 30aug11 stopped on 27sep11 freq:other.
Indication: Ovarian Cancer
Paraplatin
Dosage: freq:other auc:6
Indication: Ovarian Cancer
Start date: 2011-08-30
End date: 2011-09-27
Possible Taxol side effects in 56 year old female
Reported by a physician from France on 2011-11-28
Patient: 56 year old female
Reactions: Gastrointestinal Necrosis
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Taxol
Indication: Breast Cancer Metastatic
Start date: 2011-01-17
End date: 2011-10-10
Avastin
Indication: Breast Cancer Metastatic
Start date: 2011-01-17
End date: 2011-10-10
Possible Taxol side effects in 56 year old female
Reported by a physician from France on 2011-11-24
Patient: 56 year old female
Reactions: Mediastinitis, Gastrointestinal Necrosis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
Dosage: dose received on 10oct11 day15 10th course
Indication: Breast Cancer Metastatic
Start date: 2011-01-17
End date: 2011-10-10
Avastin
Dosage: dose received on 10oct11 day15 10th course
Indication: Breast Cancer Metastatic
Start date: 2011-01-17
End date: 2011-10-10
Possible Taxol side effects in 76 year old female
Reported by a health professional (non-physician/pharmacist) from Germany on 2011-11-16
Patient: 76 year old female, weighing 88.0 kg (193.6 pounds)
Reactions: Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Fenistil
Dosage: unk
Indication: Product Used FOR Unknown Indication
Start date: 2011-03-14
End date: 2011-07-04
Taxol
Dosage: 100-160 mg
Indication: Ovarian Cancer
Start date: 2011-03-14
End date: 2011-07-04
Ondanestron
Dosage: unk
Indication: Product Used FOR Unknown Indication
Start date: 2011-03-14
End date: 2011-07-04
Ranitidine
Dosage: unk
Indication: Product Used FOR Unknown Indication
Start date: 2011-03-14
End date: 2011-07-04
Possible Taxol side effects in 76 year old female
Reported by a physician from Germany on 2011-11-11
Patient: 76 year old female, weighing 88.0 kg (193.6 pounds)
Reactions: Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Ondansetron, 8 MG, Amp, Actavis
Start date: 2011-03-14
End date: 2011-07-04
Taxol
Indication: Ovarian Cancer
Start date: 2011-03-14
End date: 2011-07-04
Fenistil, 4 MG, Amp, Novartis
Start date: 2011-03-14
End date: 2011-07-04
Ranitidine
Start date: 2011-03-14
End date: 2011-07-04
Possible Taxol side effects in 76 year old female
Reported by a physician from Germany on 2011-11-09
Patient: 76 year old female
Reactions: Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Ondansetron
Dosage: 8 mg, nearly 3x monthly
Start date: 2011-03-14
End date: 2011-07-04
Fenistil
Dosage: 4 mg, nearly 3x monthly
Start date: 2011-03-14
End date: 2011-07-04
Taxol
Dosage: 100 - 160 mg, nearly 2x month
Indication: Ovarian Cancer
Start date: 2011-03-14
End date: 2011-07-04
Ranitidine
Dosage: 50 mg, nearly 3x monthly
Start date: 2011-03-14
End date: 2011-07-04
Possible Taxol side effects in 76 year old female
Reported by a consumer/non-health professional from Germany on 2011-11-04
Patient: 76 year old female, weighing 88.0 kg (193.6 pounds)
Reactions: Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Ranitidine
Dosage: formu: 50mg,1 df: 1ampoule nearly 3per month
Start date: 2011-03-14
End date: 2011-07-04
Fenistil
Dosage: formu: 4mg, 1df= 1ampoule nearly 3per month
Start date: 2011-03-14
End date: 2011-07-04
Ondansetron
Dosage: 1 df= 8mg ampoule nearly 3per month
Start date: 2011-03-14
End date: 2011-07-04
Taxol
Dosage: 1df = 100-160mg neraly 2 per month (cumulative dose 2120mg)
Indication: Ovarian Cancer
Start date: 2011-03-14
End date: 2011-07-04
Possible Taxol side effects in 68 year old male
Reported by a consumer/non-health professional from United States on 2011-10-24
Patient: 68 year old male
Reactions: Acute Lung Injury
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
Possible Taxol side effects in 42 year old female
Reported by a health professional (non-physician/pharmacist) from Germany on 2011-10-06
Patient: 42 year old female, weighing 86.0 kg (189.2 pounds)
Reactions: Intracranial Venous Sinus Thrombosis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Aranesp
Indication: Breast Cancer
Start date: 2007-06-14
End date: 2007-08-24
Granisetron
Dosage: on day 0 to 3
Administration route: Oral
Indication: Prophylaxis
Start date: 2007-06-13
End date: 2007-09-30
Taxol
Dosage: 40 mg/m2 (09-aug-2007 to 27-sep-2007), weekly.
Indication: Breast Cancer
Start date: 2007-08-09
End date: 2007-10-10
Cyclophosphamide
Indication: Breast Cancer
Start date: 2007-06-14
End date: 2007-07-26
Dexamethasone
Dosage: daily on day 1 to 4, 4mg (13-jun-2007 to 30-sep-2007).
Indication: Prophylaxis
Ranitidine
Dosage: 1 df= 50 units nos, once a day on day 1
Indication: Antiallergic Therapy
Epirubicin
Indication: Breast Cancer
Start date: 2007-06-14
End date: 2007-07-26
Capecitabine
Dosage: 500 mg/m2 (09-aug-2007 to 27-sep-2007), twice daily.
Administration route: Oral
Indication: Breast Cancer
Start date: 2007-08-09
End date: 2007-10-10
Other drugs received by patient: Ibuprofen
Possible Taxol side effects in 76 year old female
Reported by a physician from Germany on 2011-10-05
Patient: 76 year old female, weighing 88.0 kg (193.6 pounds)
Reactions: Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Taxol
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