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Tasigna (Nilotinib) - Chest Pain - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Chest Pain (88)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Tasigna (Nilotinib) where reactions include chest pain. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 88   Next >>

Possible Tasigna side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-17

Patient: female, weighing 55.3 kg (121.7 pounds)

Reactions: Weight Decreased, Abdominal Pain, Nasopharyngitis, Flatulence, Eye Infection, Abdominal Pain Upper, Fatigue, Food Allergy, Tooth Discolouration, Chest Pain, Liver Function Test Abnormal, Toothache, Epistaxis, White Blood Cell Count Decreased, Pneumonia, Nausea, Dental Caries, Acute Abdomen, Uveitis, Cholelithiasis, Platelet Count Decreased

Drug(s) suspected as cause:
Tasigna
    Dosage: 150 mg, bid
    Start date: 2012-04-17

Tasigna
    Dosage: 300 mg, bid
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2012-02-15
    End date: 2012-02-01



Possible Tasigna side effects in male

Reported by a physician from Japan on 2012-07-31

Patient: male

Reactions: Atrial Flutter, Drug Level Increased, C-Reactive Protein Increased, Rash Erythematous, Chest Pain, Drug Interaction, Pyrexia

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient possibly interacting with the suspect drug:
Tasigna
    Dosage: 300 mg, daily
    Administration route: Oral
    Start date: 2012-05-30

Downtensine
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-05-28

Captopril
    Dosage: 18.75 mg, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-05-28

Other drugs received by patient: Crestor; Mexiletine Hydrochloride; Technis; Lansoprazole; Proton Pump Inhibitors; Juvela Nicotinate; Uloric



Possible Tasigna side effects in 64 year old female

Reported by a physician from Spain on 2012-07-30

Patient: 64 year old female

Reactions: Electrocardiogram QT Prolonged, Vomiting, Nausea, Palpitations, Chest Pain, Lipase Increased

Drug(s) suspected as cause:
Tasigna
    Dosage: 200 mg, q12h

Tasigna
    Dosage: 400 mg, q12h
    Start date: 2012-01-10



Possible Tasigna side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-24

Patient: male

Reactions: Ischaemia, Intermittent Claudication, Pain in Extremity, Chest Pain, Blood Pressure Decreased

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Tasigna



Possible Tasigna side effects in 60 year old male

Reported by a physician from France on 2012-07-24

Patient: 60 year old male

Reactions: Ischaemia, Chest Discomfort, Angina Pectoris, Pain in Extremity, Coronary Artery Stenosis, Intermittent Claudication, Chest Pain, Arterial Occlusive Disease, Electrocardiogram Repolarisation Abnormality, LOW Density Lipoprotein Increased, Myocardial Infarction, Blood Pressure Decreased

Adverse event resulted in: life threatening event, disablity

Drug(s) suspected as cause:
Tasigna



Possible Tasigna side effects in female

Reported by a physician from United States on 2012-07-20

Patient: female, weighing 61.6 kg (135.5 pounds)

Reactions: Dyspnoea, Atrial Fibrillation, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Mitral Valve Incompetence, Ejection Fraction Decreased, Chest Pain, Right Ventricular Dysfunction, Aortic Valve Incompetence, Cardiac Failure Congestive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient: Levothyroxine Sodium; Atenolol



Possible Tasigna side effects in male

Reported by a physician from Germany on 2012-07-10

Patient: male, weighing 102.0 kg (224.4 pounds)

Reactions: Dyspnoea Exertional, Chest Pain, Acute Myocardial Infarction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient: Benserazide Hydrochloride W / Levodopa; Simvastatin; Aspirin



Possible Tasigna side effects in female

Reported by a physician from France on 2012-07-05

Patient: female

Reactions: in-Stent Coronary Artery Restenosis, Dyspnoea Exertional, Chest Pain, Femoral Arterial Stenosis, Pain, Peripheral Arterial Occlusive Disease, Coronary Artery Disease

Drug(s) suspected as cause:
Tasigna



Possible Tasigna side effects in female

Reported by a physician from France on 2012-07-05

Patient: female, weighing 60.0 kg (132.0 pounds)

Reactions: Pain in Extremity, Chest Pain, Peripheral Arterial Occlusive Disease, Carotid Artery Occlusion, Coronary Artery Disease, Gait Disturbance

Drug(s) suspected as cause:
Tasigna
    Dosage: 800 mg, daily
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2008-05-26
    End date: 2009-05-31

Tasigna
    Dosage: 200 mg, daily
    Administration route: Oral
    Start date: 2009-06-01
    End date: 2009-12-10



Possible Tasigna side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-05

Patient: female, weighing 55.3 kg (121.7 pounds)

Reactions: Weight Decreased, Abdominal Pain, Nasopharyngitis, Flatulence, Eye Infection, Abdominal Pain Upper, Pancreatic Disorder, Fatigue, Food Allergy, Tooth Discolouration, Liver Function Test Abnormal, Chest Pain, Toothache, Epistaxis, White Blood Cell Count Decreased, Pneumonia, Nausea, Dental Caries, Acute Abdomen, Uveitis, Cholelithiasis, Platelet Count Decreased

Drug(s) suspected as cause:
Tasigna



Possible Tasigna side effects in male

Reported by a physician from France on 2012-07-02

Patient: male, weighing 77.0 kg (169.4 pounds)

Reactions: Chest Pain, Arrhythmia, Abdominal Pain Upper

Adverse event resulted in: death

Drug(s) suspected as cause:
Tasigna



Possible Tasigna side effects in male

Reported by a physician from Italy on 2012-06-29

Patient: male, weighing 47.0 kg (103.4 pounds)

Reactions: Chest Pain, Angina Unstable, Coronary Artery Stenosis, Acute Coronary Syndrome

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient: Ramipril; Bisoprolol Fumarate; Atorvastatin; Aspirin; Clopidogrel; Metformin HCL



Possible Tasigna side effects in 64 year old female

Reported by a physician from Spain on 2012-06-26

Patient: 64 year old female

Reactions: Electrocardiogram QT Prolonged, Vomiting, Nausea, Palpitations, Chest Pain, Lipase Increased

Drug(s) suspected as cause:
Tasigna
    Dosage: 400 mg, q12h
    Start date: 2012-01-10

Tasigna
    Dosage: 200 mg, q12h



Possible Tasigna side effects in male

Reported by a physician from United States on 2012-06-20

Patient: male, weighing 79.6 kg (175.1 pounds)

Reactions: Chest Pain, Coronary Artery Disease, Acute Myocardial Infarction, Concomitant Disease Progression, Abdominal Pain Upper

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tasigna
    Dosage: 400 mg, qd
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2008-04-07
    End date: 2010-09-01

Tasigna
    Dosage: 400 mg, qd
    Administration route: Oral
    End date: 2010-11-12

Tasigna
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2012-05-15

Tasigna
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2010-11-13
    End date: 2010-11-17

Tasigna
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2010-11-18
    End date: 2011-09-02

Tasigna
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2011-09-12
    End date: 2012-04-02

Tasigna
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2012-04-04
    End date: 2012-05-11

Other drugs received by patient: Toprol-XL; Aspirin; Plavix; Metoprolol Tartrate; Metoprolol Tartrate; Pravastatin; Lisinopril



Possible Tasigna side effects in male

Reported by a physician from Japan on 2012-06-19

Patient: male

Reactions: Atrial Flutter, C-Reactive Protein Increased, Drug Level Increased, Chest Pain, Rash Erythematous, Drug Interaction, Pyrexia

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient possibly interacting with the suspect drug:
Captopril
    Dosage: 18.75 mg, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-05-28

Tasigna
    Dosage: 300 mg, daily
    Administration route: Oral
    Start date: 2012-05-30

Downtensine
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-05-28

Other drugs received by patient: Juvela Nicotinate; Febuxostat; Lansoprazole; Mexiletine Hydrochloride; Proton Pump Inhibitors; Crestor; Technis



Possible Tasigna side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-19

Patient: female

Reactions: Lactose Intolerance, Pain, Gastrointestinal Inflammation, Eructation, Abdominal Discomfort, Fatigue, Arthropathy, Palpitations, Chest Pain, Coordination Abnormal, Gastrooesophageal Reflux Disease, Epistaxis, Decreased Appetite, Cough, Blood Pressure Increased, Dyspnoea, Gingival Bleeding, Polyp, Nausea, Retching, Rhinorrhoea, Left Ventricular Hypertrophy, Osteopenia, Lung Disorder, Platelet Count Decreased, Memory Impairment

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient: Herbal Extracts NOS; Flovent; Fish OIL; COD-Liver OIL; Zyrtec; Calcium; Nexium; Tramadol HCL; Coreg; Coenzyme Q10; Tricor



Possible Tasigna side effects in 80 year old female

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-06-11

Patient: 80 year old female

Reactions: Dyspnoea, Hyperglycaemia, Systolic Dysfunction, Haemoglobin Decreased, Neck Pain, Chest Pain, Troponin I Increased, Acute Myocardial Infarction, Leukocytosis

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient: Bisoprolol Fumarate; Aspirin; Allopurinol; Aranesp; Sintrom; Omeprazole; Ramipril; Oral Antidiabetics; Lasix; Repaglinide; Rocaltrol; Folina; Furosemide; Glucobay



Possible Tasigna side effects in male

Reported by a physician from Japan on 2012-06-11

Patient: male

Reactions: Electrocardiogram ST Segment Depression, C-Reactive Protein Increased, Atrial Flutter, Chest Pain, Rash Erythematous, Troponin Increased, Pyrexia

Drug(s) suspected as cause:
Tasigna
    Dosage: 300 mg, daily
    Administration route: Oral
    Start date: 2012-05-30

Captopril
    Dosage: 18.75 mg, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-05-28

Downtensine
    Dosage: 10 mg, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-05-28

Tasigna
    Dosage: 600 mg, daily
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2012-04-17
    End date: 2012-04-24

Other drugs received by patient: Proton Pump Inhibitors; Technis; Crestor; Lansoprazole; Mexiletine Hydrochloride; Febuxostat; Juvela Nicotinate



Possible Tasigna side effects in male

Reported by a consumer/non-health professional from United States on 2012-06-08

Patient: male

Reactions: Weight Decreased, Abasia, Blood Thyroid Stimulating Hormone Increased, Pyrexia, Renal Artery Stenosis, Gastritis, Oesophagitis, Chest Pain, Tendonitis, Cardiac Failure Congestive, Fluid Retention, Muscle Spasms, Pain in Extremity, Atrial Fibrillation, Rash, Alopecia, Dehydration, Hyperthyroidism

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient: Ramipril; Amlodipine



Possible Tasigna side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-06

Patient: female, weighing 55.3 kg (121.7 pounds)

Reactions: Weight Decreased, Abdominal Pain, Nasopharyngitis, Flatulence, Eye Infection, Abdominal Pain Upper, Pancreatic Disorder, Fatigue, Food Allergy, Tooth Discolouration, Liver Function Test Abnormal, Chest Pain, Toothache, Epistaxis, White Blood Cell Count Decreased, Pneumonia, Nausea, Acute Abdomen, Cholelithiasis, Platelet Count Decreased

Drug(s) suspected as cause:
Tasigna



Possible Tasigna side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-05

Patient: female

Reactions: Dyspnoea, Cardiac Failure Chronic, Pneumonia, Chest Pain, Blood Pressure Inadequately Controlled, Cardiac Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient: Lasix; Verapamil HCL; Zyloprim; Lopressor; Digoxin; Ferrous Fumarate; Aspirin; Cardizem; Rythmol; Zocor; Gabapentin; Pepcid



Possible Tasigna side effects in male

Reported by a physician from Germany on 2012-06-05

Patient: male, weighing 75.0 kg (165.0 pounds)

Reactions: Electrocardiogram QT Prolonged, Pericardial Effusion, Blood Calcium Decreased, Abdominal Discomfort, Fatigue, C-Reactive Protein Increased, Pulmonary Congestion, Chest Pain, Pleural Effusion, Blood Alkaline Phosphatase Increased, Dyspnoea, Nausea, Tachyarrhythmia, Blood Lactate Dehydrogenase Increased, Atrial Fibrillation, General Physical Health Deterioration, Diarrhoea, Asthenia, Inflammation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tasigna
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2010-10-24
    End date: 2010-11-13

Tasigna
    Dosage: 200 mg, bid
    Administration route: Oral
    Start date: 2011-10-18

Tasigna
    Dosage: 400 mg, bid
    Administration route: Oral
    Start date: 2010-01-01
    End date: 2010-10-18

Tasigna
    Start date: 2010-12-14
    End date: 2011-02-18

Tasigna
    Dosage: 300 mg, bid
    Administration route: Oral
    Start date: 2011-04-06
    End date: 2011-10-17

Tasigna
    Dosage: 800 mg, daily
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2009-11-21
    End date: 2010-12-03

Other drugs received by patient: Doxazosin; Aspirin; Ofloxacin; Corvaton - Slow Release; Amlodipine; Furosemide; Cyanocobalamin; Pantoprazole; Allopurinol; Ciprofloxacin; Candesartan Cilexetil; Imodium; Simvastatin; Epogen; Torsemide; Metoprolol Succinate; Carvedilol; Digimerck



Possible Tasigna side effects in 80 year old

Reported by a physician from United States on 2012-05-31

Patient: 80 year old

Reactions: Dyspnoea, Chest Pain, Hyperhidrosis

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient: Amiodarone HCL



Possible Tasigna side effects in male

Reported by a physician from United States on 2012-05-24

Patient: male, weighing 82.5 kg (181.6 pounds)

Reactions: Electrocardiogram QT Prolonged, Blood Bilirubin Increased, Pain, Fatigue, Scrotal Oedema, Chest Pain, Malignant Melanoma, Testicular Swelling, Melanocytic Naevus, Muscle Spasms, Decreased Appetite, Cough, Blood Glucose Increased, Blood Alkaline Phosphatase Increased, Pain in Extremity, Musculoskeletal Pain, Rash, Skin Papilloma, Neoplasm Malignant, Alopecia, Testicular Pain, Penis Carcinoma, Scrotal Infection

Drug(s) suspected as cause:
Tasigna
    Dosage: 300 mg, bid
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2011-03-04

Tasigna
    Dosage: 300 mg, bid
    Administration route: Oral

Tasigna
    Dosage: 300 mg, bid
    Administration route: Oral
    Start date: 2012-02-01

Other drugs received by patient: Zocor; Lisinopril; Omeprazole; Allopurinol



Possible Tasigna side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-24

Patient: female, weighing 55.3 kg (121.7 pounds)

Reactions: Weight Decreased, Abdominal Pain, Nasopharyngitis, Flatulence, Eye Infection, Abdominal Pain Upper, Pancreatic Disorder, Fatigue, Food Allergy, Tooth Discolouration, Chest Pain, Liver Function Test Abnormal, Toothache, Epistaxis, White Blood Cell Count Decreased, Pneumonia, Nausea, Acute Abdomen, Cholelithiasis, Platelet Count Decreased

Drug(s) suspected as cause:
Tasigna



Possible Tasigna side effects in female

Reported by a physician from United Kingdom on 2012-05-21

Patient: female, weighing 50.0 kg (110.0 pounds)

Reactions: Electrocardiogram ST Segment Depression, Pulmonary Hypertension, Blood Bilirubin Increased, Rales, Pyrexia, Device Related Infection, Tricuspid Valve Incompetence, Cardiomegaly, Palpitations, Skin Haemorrhage, Blood Creatinine Increased, Cardiac Failure Congestive, Gingival Bleeding, Left Ventricular END-Diastolic Pressure Decreased, Blast Crisis in Myelogenous Leukaemia, Angina Pectoris, Hypotension, Anaemia, Haematotoxicity, Platelet Count Decreased, Aortic Valve Incompetence, Left Ventricular Failure, Chest Pain, Thrombocytopenia, Blood Glucose Increased, White Blood Cell Count Decreased, Dyspnoea AT Rest, Cardiogenic Shock, Chronic Myeloid Leukaemia, Heart Rate Increased, Mitral Valve Incompetence, Shock, Leukopenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
RED Blood Cells

Tasigna
    Dosage: 800 mg, bid
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2007-04-25
    End date: 2007-04-28

Other drugs received by patient: Isosorbide Mononitrate; Metoprolol Tartrate



Possible Tasigna side effects in male

Reported by a physician from United States on 2012-05-20

Patient: male, weighing 84.3 kg (185.5 pounds)

Reactions: Weight Decreased, Rales, Myocardial Ischaemia, Pyrexia, Erythema, Herpes Zoster, Dyspepsia, Oesophagitis, Oedema Peripheral, Pulmonary Oedema, Blood Pressure Abnormal, Haemolytic Uraemic Syndrome, Sinus Arrhythmia, Blood Creatinine Increased, Cough, Gastritis Atrophic, Cardiac Failure Congestive, Dysphagia, Pneumonia, Chest Discomfort, Anaemia, Left Ventricular Hypertrophy, Respiratory Distress, Cardiomyopathy, Joint Injury, Breath Sounds Abnormal, Dehydration, Scan Myocardial Perfusion Abnormal, Atelectasis, Electrocardiogram QT Prolonged, Performance Status Decreased, Ventricular Hypokinesia, Constipation, Fall, Urinary Hesitation, Abdominal Pain Upper, Fatigue, Beta Haemolytic Streptococcal Infection, Chest Pain, Pleural Effusion, Thrombocytopenia, Lethargy, Blood Urea Increased, Dyspnoea, Jugular Vein Distension, Post Herpetic Neuralgia, Renal Failure Chronic, Chronic Myeloid Leukaemia, Lung Disorder, Biopsy Mucosa Abnormal, Sepsis, Ejection Fraction Decreased, Hypoperfusion, Lung Infiltration, Asthenia, Deep Vein Thrombosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Imatinib Mesylate
    Dosage: no treatment
    Start date: 2008-12-21
    End date: 2008-12-23

Amiodarone HCL

Imatinib Mesylate
    Dosage: 400 mg, qd
    Start date: 2008-05-02

Imatinib Mesylate
    Dosage: 400 mg
    Administration route: Oral
    Start date: 2008-12-24

Tasigna
    Dosage: 800 mg, qd
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2009-06-19
    End date: 2009-06-24

Imatinib Mesylate
    Dosage: 400 mg, qd
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2007-11-16

Imatinib Mesylate
    Dosage: no treatment
    Start date: 2008-04-24
    End date: 2008-05-01

Chemotherapeutics NOS

Other drugs received by patient: Allopurinol; Furosemide; Potassium Chloride; Flomax; Prilosec; Multi-Vitamins; Ascorbic Acid; Paclitaxel; Norvasc; Diovan; Lasix; Aspirin; Vicodin; Lidoderm; Compazine; Synthroid; Lipitor; Niaspan; Amlodipine Besylate; Bystolic; Cardura; Omeprazole; Toprol-XL; Neurontin; Megace; Clonidine



Possible Tasigna side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-17

Patient: female, weighing 108.9 kg (239.6 pounds)

Reactions: Back Pain, Chest Discomfort, Dyslipidaemia, Coronary Artery Disease, Left Ventricular Hypertrophy, Concomitant Disease Progression, Obesity, Chest Pain, Troponin I Increased, Hypertension, Myocardial Infarction, Electrocardiogram Repolarisation Abnormality, QRS Axis Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tasigna
    Dosage: 300 mg, bid
    Administration route: Oral
    Start date: 2012-02-08

Tasigna
    Dosage: 300 mg, bid
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2008-06-04
    End date: 2011-02-11

Tasigna
    Dosage: 300 mg, bid
    Administration route: Oral
    End date: 2012-02-05

Other drugs received by patient: Hydrochlorothiazide; Aspirin; Cozaar; Cozaar; Norvasc; Simvastatin; Metoprolol Succinate; Plavix



Possible Tasigna side effects in female

Reported by a physician from United States on 2012-05-11

Patient: female

Reactions: Cardiac Flutter, Fatigue, Heart Rate Increased, Chest Pain, Atrial Fibrillation

Drug(s) suspected as cause:
Tasigna

Other drugs received by patient: Allopurinol; Lipitor; Warfarin Sodium; Levothyroxine Sodium; Atenolol; Pantoprazole; Diovan; Niaspan; Calcium Carbonate; Cyanocobalamin



Possible Tasigna side effects in 80 year old male

Reported by a physician from Spain on 2012-05-09

Patient: 80 year old male

Reactions: Abdominal Pain, Pruritus, Chest Pain, Pleural Effusion

Drug(s) suspected as cause:
Tasigna
    Dosage: 150 mg, qd
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2011-08-16

Tasigna
    Dosage: 75 mg qd
    Administration route: Oral

Other drugs received by patient: Escitalopram Oxalate



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