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Spironolactone (Spironolactone) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (58)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Spironolactone life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 58   Next >>

Possible Spironolactone side effects in 53 year old male

Reported by a physician from United States on 2012-08-16

Patient: 53 year old male

Reactions: Cardiac Arrest

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Spironolactone
    Indication: Cardiac Failure Congestive

Furosemide
    Indication: Cardiac Failure Congestive



Possible Spironolactone side effects in 87 year old male

Reported by a physician from United States on 2012-08-08

Patient: 87 year old male, weighing 84.8 kg (186.6 pounds)

Reactions: Renal Failure

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Spironolactone
    Indication: Cardiac Failure Congestive
    Start date: 2009-01-21

Zaroxolyn
    Indication: Cardiac Failure Congestive
    Start date: 2012-01-29

Torsemide
    Indication: Cardiac Failure Congestive
    Start date: 2010-08-25

Tafamidis Meglumine
    Administration route: Oral
    Indication: Amyloidosis
    Start date: 2008-12-05

Other drugs received by patient: Ambien; Synthroid; Coumadin; Lipitor; Allopurinol; Colchicine; Colchicine



Possible Spironolactone side effects in 87 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient: 87 year old male, weighing 84.8 kg (186.6 pounds)

Reactions: Renal Failure, Cardiac Failure Congestive

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Spironolactone
    Dosage: 12.5 mg (12.5 mg,1 in 1 d),oral
    Administration route: Oral
    Indication: Cardiac Failure Congestive
    Start date: 2009-01-21

Torsemide
    Dosage: 200 mg (100 mg,2 in 1 d),oral
    Administration route: Oral
    Indication: Cardiac Failure Congestive
    Start date: 2010-08-25

Tafamidis Meglumine
    Dosage: 20 mg (20 mg, 1 in 1 d),oral
    Administration route: Oral
    Indication: Amyloidosis
    Start date: 2008-12-05

Zaroxolyn
    Dosage: as needed (2.5 mg),oral
    Administration route: Oral
    Indication: Cardiac Failure Congestive
    Start date: 2010-01-29

Other drugs received by patient: Ambien; Synthroid; Colchicine; Lipitor; Allopurinol; Coumadin



Possible Spironolactone side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-24

Patient: female

Reactions: Renal Failure Acute

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Spironolactone
    Dosage: 50 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-06-18

Lasix
    Dosage: 40 mg, daily
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Vancomycin Hydrochloride
    Dosage: 1 g, tid
    Indication: Device Related Infection
    Start date: 2012-05-18
    End date: 2012-06-18

Losartan Potassium
    Dosage: 100 mg, daily
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-06-18

Gentamicin
    Dosage: 320 mg, daily
    Administration route: Oral
    Indication: Device Related Infection
    Start date: 2012-05-18
    End date: 2012-06-18

Ketoprofen
    Dosage: 1 df, bid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    End date: 2012-06-18

Other drugs received by patient: Ceftriaxone Aguettant; Eupressyl / 00631801 /; Tramadol HCL; Sitagliptin Phosphate



Possible Spironolactone side effects in 87 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-23

Patient: 87 year old male, weighing 84.8 kg (186.6 pounds)

Reactions: Renal Failure, Peritoneal Dialysis, Condition Aggravated, Cardiac Failure Congestive

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Zaroxolyn
    Indication: Cardiac Failure Congestive
    Start date: 2012-01-29

Spironolactone
    Indication: Cardiac Failure Congestive
    Start date: 2009-01-21

Torsemide
    Indication: Cardiac Failure Congestive
    Start date: 2010-08-25

Tafamidis Meglumine
    Dosage: 20mg (20 mg, 1 in 1 d),oral
    Administration route: Oral
    Indication: Amyloidosis
    Start date: 2008-12-05

Other drugs received by patient: Ambien; Warfarin Sodium; Colchicine (Colchidine); Allopurinol; Synthroid; Lipitor



Possible Spironolactone side effects in female

Reported by a physician from Germany on 2012-07-13

Patient: female, weighing 68.0 kg (149.6 pounds)

Reactions: Renal Failure Acute

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Amiodarone HCL
    Dosage: 200 mg
    Indication: Atrial Fibrillation
    Start date: 2012-06-14

Pradaxa
    Dosage: 220 mg
    Indication: Atrial Fibrillation
    Start date: 2012-06-14

Spironolactone
    Dosage: 25 mg
    Indication: Atrial Fibrillation
    Start date: 2012-06-14

Other drugs received by patient: Simvastatin; Metoprolol Tartrate; Coapprovel



Possible Spironolactone side effects in male

Reported by a physician from Germany on 2012-07-09

Patient: male, weighing 120.1 kg (264.2 pounds)

Reactions: Endocarditis Staphylococcal, Pneumonia, Cardiac Failure, Gastroenteritis Clostridial, Pleural Effusion, Device Related Infection, Septic Shock, Polyneuropathy

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Carvedilol
    Dosage: 25 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2000-01-01

Spironolactone
    Dosage: 25 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2007-01-01

Simvastatin
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Hypercholesterolaemia
    Start date: 2010-01-01

Allopurinol
    Dosage: 100 mg, qd
    Administration route: Oral
    Indication: Gout
    Start date: 2005-01-01

Lisinopril
    Dosage: 20 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2009-01-01

NO Treatment Received
    Dosage: no treatment
    Indication: Gout



Possible Spironolactone side effects in

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-08

Patient:

Reactions: Syncope, Atrioventricular Block Complete, Blood Potassium Increased, Blood Pressure Decreased, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Digoxin
    Dosage: 62.5 mg, qd
    Indication: Product Used FOR Unknown Indication
    End date: 2008-04-14

Spironolactone
    Dosage: 25 mg, qd
    Indication: Product Used FOR Unknown Indication
    Start date: 2008-03-25
    End date: 2008-04-14

Bisoprolol Fumarate
    Dosage: 10 mg, qd
    Indication: Product Used FOR Unknown Indication
    End date: 2008-04-14

Ramipril
    Dosage: 3.75 mg, qd
    Indication: Cardiac Failure Congestive
    End date: 2008-04-14

Amiloride Hydrochloride
    Dosage: 10 mg, qd
    Indication: Oedema
    End date: 2008-04-14

Ramipril
    Indication: Hypertension

Other drugs received by patient: Warfarin Sodium; Gabapentin; Bumetanide



Possible Spironolactone side effects in 77 year old female

Reported by a physician from Japan on 2012-06-05

Patient: 77 year old female, weighing 49.0 kg (107.8 pounds)

Reactions: Renal Impairment, Hepatic Function Abnormal, Hypoproteinaemia, Disseminated Intravascular Coagulation, Pleural Effusion, Blood Potassium Increased, Erythema Multiforme, Generalised Oedema

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Lansoprazole
    Dosage: 15 mg, 1x/day
    Administration route: Oral
    Indication: Gastric Ulcer
    Start date: 2005-05-02
    End date: 2012-01-01

Furosemide
    Dosage: 20 mg, 1x/day
    Administration route: Oral
    Indication: Renal Failure Chronic
    Start date: 2005-08-17
    End date: 2012-01-01

Spironolactone
    Dosage: 25 mg, 1x/day
    Administration route: Oral
    Indication: Renal Failure Chronic
    Start date: 2010-07-04
    End date: 2012-01-01

Allopurinol
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Hyperuricaemia
    Start date: 2006-12-25
    End date: 2012-01-01

Levofloxacin
    Dosage: 500 mg, 2x/day
    Administration route: Oral
    Indication: Urinary Tract Infection
    Start date: 2012-01-18
    End date: 2012-01-18

Celebrex
    Dosage: 100 mg once daily as needed
    Administration route: Oral
    Indication: Pain
    Start date: 2012-01-10
    End date: 2012-01-01

Other drugs received by patient: Onon; Diclofenac Sodium



Possible Spironolactone side effects in 77 year old female

Reported by a physician from Japan on 2012-05-30

Patient: 77 year old female, weighing 49.0 kg (107.8 pounds)

Reactions: Renal Impairment, Hepatic Function Abnormal, Hypoproteinaemia, Disseminated Intravascular Coagulation, Pleural Effusion, Blood Potassium Increased, Erythema Multiforme, Generalised Oedema

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Celebrex
    Dosage: 100 mg once daily as needed
    Administration route: Oral
    Indication: Pain
    Start date: 2012-01-10
    End date: 2012-01-01

Spironolactone
    Dosage: 25 mg, 1x/day
    Administration route: Oral
    Indication: Renal Failure Chronic
    Start date: 2010-07-04
    End date: 2012-01-01

Furosemide
    Dosage: 20 mg, 1x/day
    Administration route: Oral
    Indication: Renal Failure Chronic
    Start date: 2005-08-17
    End date: 2012-01-01

Levofloxacin
    Dosage: 500 mg, 2x/day
    Administration route: Oral
    Indication: Urinary Tract Infection
    Start date: 2012-01-18
    End date: 2012-01-18

Allopurinol
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Hyperuricaemia
    Start date: 2006-12-25
    End date: 2012-01-01

Lansoprazole
    Dosage: 15 mg, 1x/day
    Administration route: Oral
    Indication: Gastric Ulcer
    Start date: 2005-05-02
    End date: 2012-01-01

Other drugs received by patient: Onon; Diclofenac Sodium



Possible Spironolactone side effects in 84 year old female

Reported by a physician from Japan on 2012-05-29

Patient: 84 year old female

Reactions: Metabolic Acidosis, Electrocardiogram QRS Complex Prolonged, Spinal Fracture, Hyperkalaemia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Spironolactone
    Dosage: 25 mg/day
    Administration route: Oral

Aliskiren Fumarate
    Dosage: 150 mg/day
    Administration route: Oral



Possible Spironolactone side effects in 69 year old female

Reported by a physician from United States on 2012-05-25

Patient: 69 year old female

Reactions: Death, Hepatic Encephalopathy, Cardiac Cirrhosis

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Furosemide
    Indication: Portal Hypertension

Lactulose
    Indication: Portal Hypertension

Doxorubicin HCL
    Indication: Breast Cancer Metastatic

Cyclophosphamide
    Indication: Breast Cancer Metastatic

Spironolactone
    Indication: Portal Hypertension



Possible Spironolactone side effects in 64 year old male

Reported by a physician from United Kingdom on 2012-05-22

Patient: 64 year old male, weighing 103.4 kg (227.5 pounds)

Reactions: Hyperkalaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Spironolactone

Other drugs received by patient: Lansoprazole; Lantus; Loperamide; Fluticasone Propionate / Salmeterol; Zopiclone; Ventolin; Lisinopril; Gabapentin; Furosemide; Novorapid; Paroxetine; Atorvastatin Calcium; Acetylsalicylic Acid; Loperamide; Loperamide; Acetaminophen; Loperamide; Codeine Phosphate; Chloramphenicol



Possible Spironolactone side effects in 84 year old female

Reported by a physician from Japan on 2012-04-27

Patient: 84 year old female

Reactions: Metabolic Acidosis, Spinal Fracture, Hyperkalaemia, Electrocardiogram QRS Complex Prolonged

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Aliskiren Fumarate
    Dosage: 150 mg/day
    Administration route: Oral

Spironolactone
    Dosage: 25 mg/day
    Administration route: Oral



Possible Spironolactone side effects in 68 year old male

Reported by a physician from Germany on 2012-04-26

Patient: 68 year old male, weighing 80.0 kg (176.0 pounds)

Reactions: Multi-Organ Failure, Sepsis, Toxic Epidermal Necrolysis

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Spironolactone

Ceftazidime
    Start date: 2009-11-01
    End date: 2009-11-06

Maxipime
    Start date: 2009-10-30
    End date: 2009-11-01

Vancomycin
    Dosage: interrupted:01nov09 (38 dys)
    Administration route: Oral
    Start date: 2009-09-25



Possible Spironolactone side effects in 44 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-25

Patient: 44 year old male

Reactions: Hypoxia, Bradycardia, Asthenia, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Saxagliptin (Saxagliptin)
    Indication: Type 2 Diabetes Mellitus

Metoprolol Tartrate
    Indication: Product Used FOR Unknown Indication

Blinded Therapy
    Dosage: 40 iu
    Indication: Type 2 Diabetes Mellitus
    Start date: 2011-02-02
    End date: 2011-05-17

Diovan
    Indication: Product Used FOR Unknown Indication

Lasix
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Indication: Product Used FOR Unknown Indication

Verapamil Hydrochloride
    Indication: Product Used FOR Unknown Indication

Lantus
    Dosage: 40 iu
    Indication: Diabetes Mellitus
    Start date: 2011-02-02
    End date: 2011-05-17

Other drugs received by patient: Anti-Coagulant (Anticoagulant Sodium Citrate); Aspirin; Angiotensin Converting Enzyme; Diuretics (Diuretics); Ezetimibe; Beta Blocker (Beta Blocker Agents); Aldosterone Inhibitor (Aldosterone Antagonists)



Possible Spironolactone side effects in 84 year old female

Reported by a physician from Japan on 2012-04-23

Patient: 84 year old female

Reactions: Metabolic Acidosis, Hyperkalaemia, Spinal Fracture, Electrocardiogram QRS Complex Prolonged

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Spironolactone
    Dosage: 25 mg/day
    Administration route: Oral

Aliskiren Fumarate
    Dosage: 150 mg/day
    Administration route: Oral



Possible Spironolactone side effects in male

Reported by a physician from United States on 2012-04-20

Patient: male

Reactions: Hyperkalaemia, Hypoxia, Bradycardia, Blood Creatinine Increased, Asthenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Lasix

Diovan

Metoprolol Tartrate

Verapamil Hydrochloride

Spironolactone

Other drugs received by patient: Diuretics; Aldosterone; Beta Blocking Agents; Angiotensin Converting Enzyme Blockers; Saxagliptin; Insulin Glargine; Anticoagulants



Possible Spironolactone side effects in male

Reported by a consumer/non-health professional from United States on 2012-04-20

Patient: male

Reactions: Hyperkalaemia, Hypoxia, Bradycardia, Asthenia, Blood Creatinine Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Diovan

Spironolactone

Lasix

Verapamil Hydrochloride

Metoprolol Tartrate

Other drugs received by patient: Angiotensin Converting Enzyme Blockers; Aldosterone; Insulin Glargine; Anticoagulants; Diuretics; Beta Blocking Agents; Saxagliptin



Possible Spironolactone side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-18

Patient: male

Reactions: Hyperkalaemia, Blood Creatinine Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Diovan

Verapamil HCL
    Dosage: unk

Spironolactone

Blinded Therapy
    Dosage: 40 iu, unk
    Indication: Type 2 Diabetes Mellitus
    Start date: 2011-02-02
    End date: 2011-05-17

Metoprolol Tartrate
    Dosage: unk

Lantus
    Dosage: 40 iu, unk
    Indication: Diabetes Mellitus

Lasix
    Dosage: unk

Other drugs received by patient: Acetylsalicylic Acid; Ezetimibe



Possible Spironolactone side effects in female

Reported by a physician from Germany on 2012-04-05

Patient: female, weighing 72.0 kg (158.4 pounds)

Reactions: Haemoglobin Decreased, Klebsiella Infection, Haematochezia, Colitis Ischaemic, White Blood Cell Count Decreased, Renal Failure, Diarrhoea, Dehydration, General Physical Health Deterioration, Thrombocytopenia, Faeces Discoloured

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Spironolactone
    Dosage: unk
    Indication: Diuretic Therapy
    End date: 2012-03-15

Inc424
    Dosage: 15 mg, bid
    Administration route: Oral
    Indication: Myelofibrosis
    Start date: 2012-03-01
    End date: 2012-03-16

Other drugs received by patient: Allopurinol; Ramipril



Possible Spironolactone side effects in 60 year old male

Reported by a physician from Japan on 2012-04-04

Patient: 60 year old male

Reactions: Hyperkalaemia, Embolic Stroke, Bradycardia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Spironolactone
    Dosage: unk
    Indication: Ascites

Spironolactone
    Indication: Pleural Effusion



Possible Spironolactone side effects in 74 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-26

Patient: 74 year old male, weighing 81.2 kg (178.6 pounds)

Reactions: Excoriation, Anaemia, Hypotension, Neutropenic Sepsis, Tachycardia, Mental Status Changes, Atrial Fibrillation, Pyrexia, Fall, Cardiac Failure, Diarrhoea, Neutropenia, Cardiac Arrest, Lethargy, Cough

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Prednisone
    Administration route: Oral
    Start date: 2012-02-02
    End date: 2012-02-15

Lasix
    Indication: Cardiac Disorder
    End date: 2012-02-22

Matulane
    Administration route: Oral
    Start date: 2012-02-02
    End date: 2012-02-15

Spironolactone
    Indication: Cardiac Disorder
    End date: 2012-02-22

Coreg
    Indication: Cardiac Disorder
    End date: 2012-02-22

Cytoxan
    Start date: 2012-02-09
    End date: 2012-02-16

Lisinopril
    Indication: Cardiac Disorder
    End date: 2012-02-22

Vinblastine Sulfate
    Start date: 2012-02-09
    End date: 2012-02-16

Other drugs received by patient: Levofloxacin; Prevacid; Tamsulosin HCL; Klor-CON; Folic Acid; Multi-Vitamins; Bleomycin Sulfate; Dacarbazine; Lidocaine; Zofran; Doxorubicin HCL



Possible Spironolactone side effects in 74 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-08

Patient: 74 year old male, weighing 81.2 kg (178.6 pounds)

Reactions: Confusional State, Excoriation, Anaemia, Neutropenic Sepsis, Atrial Fibrillation, Condition Aggravated, Mental Status Changes, Fall, Diarrhoea, Cardiac Failure, Cardiac Arrest, Shock

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Matulane
    Dosage: 200 mg; qd; po
    Administration route: Oral
    Indication: Hodgkin's Disease Nodular Sclerosis Stage Unspecified
    Start date: 2012-02-02
    End date: 2012-02-15

Cytoxan
    Dosage: 1.186 mg;qw; iv
    Indication: Hodgkin's Disease Nodular Sclerosis Stage Unspecified
    Start date: 2012-02-09
    End date: 2012-02-16

Lisinopril
    Indication: Cardiac Disorder
    End date: 2012-02-22

Coreg
    Indication: Cardiac Disorder
    End date: 2012-02-22

Prednisone TAB
    Dosage: 80 mg; qd; po
    Administration route: Oral
    Indication: Hodgkin's Disease Nodular Sclerosis Stage Unspecified
    Start date: 2012-02-02
    End date: 2012-02-15

Vinblastine Sulfate
    Dosage: 12 mg;qw; iv
    Indication: Hodgkin's Disease Nodular Sclerosis Stage Unspecified
    Start date: 2012-02-09
    End date: 2012-02-16

Lasix
    Indication: Cardiac Disorder
    End date: 2012-02-22

Spironolactone
    Indication: Cardiac Disorder
    End date: 2012-02-22

Other drugs received by patient: Klor-CON; Doxorubicin HCL; Centrum Silver / 01292501 /; Tamsulosin HCL; Folic Acid; Lidocaine; Zofran; Levofloxacin; Prevacid; Bleomycin Sulfate; Dacarbazine



Possible Spironolactone side effects in 75 year old male

Reported by a physician from Norway on 2012-02-23

Patient: 75 year old male

Reactions: Peripheral Coldness, Confusional State, Metabolic Acidosis, Hyperkalaemia, Hypotension, Pulmonary Embolism, Bundle Branch Block Left, General Physical Health Deterioration, Drug Interaction, Cardiogenic Shock, Haemodialysis, Bradycardia, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Ramipril
    Dosage: 10 mg (10 mg, 1 in 1 d)
    Indication: Cardiac Failure

Metoprolol Tartrate
    Dosage: 100 mg (100 mg, 1 in d)
    Indication: Cardiac Failure

Spironolactone
    Dosage: 25 mg (25 mg, 1 in1 d)
    Indication: Cardiac Failure

Other drugs received by patient: Bumetanid (Bumetanide); Digitoxin TAB



Possible Spironolactone side effects in 78 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-02-15

Patient: 78 year old male

Reactions: Hyperkalaemia, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Ramipril
    Indication: Hypertension

Cotrim
    Dosage: 1960 mg, unk
    Administration route: Oral
    Indication: Peritonitis Bacterial
    Start date: 2009-08-20
    End date: 2009-09-09

Spironolactone
    Dosage: 100 mg, qid
    Administration route: Oral
    Indication: Alcoholic Liver Disease
    End date: 2009-09-09

Cotrim
    Indication: Prophylaxis

Ramipril
    Dosage: 2.5 mg, qd
    Administration route: Oral
    Indication: Myocardial Ischaemia
    End date: 2009-09-09

Other drugs received by patient: Novomix; Allopurinol; Lansoprazole; Thiamine HCL; Nitroglycerin; Isosorbide Mononitrate; Lactulose; Sucralfate; Aspirin; Propranolol; Tamsulosin HCL



Possible Spironolactone side effects in 81 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-02-14

Patient: 81 year old female

Reactions: Hyperkalaemia, Circulatory Collapse, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Spironolactone
    Administration route: Oral
    Indication: Cardiac Failure Chronic
    Start date: 2011-01-01
    End date: 2011-11-14

Januvia
    Administration route: Oral
    Start date: 2011-01-01
    End date: 2011-11-23

Pantoprazole Sodium
    Administration route: Oral
    Start date: 2011-01-01
    End date: 2011-11-23

Ezetimibe
    Administration route: Oral
    Start date: 2011-01-01
    End date: 2011-11-23

Fluindione
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2011-01-01
    End date: 2011-11-23

Bisoprolol
    Administration route: Oral
    Start date: 2011-01-01
    End date: 2011-11-23

Candesartan Cilexetil and Hydrochlorothiazide
    Administration route: Oral
    Indication: Cardiac Failure Chronic
    Start date: 2011-01-01
    End date: 2011-11-23

Other drugs received by patient: Furosemide; Furosemide; Furosemide



Possible Spironolactone side effects in 71 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-02-13

Patient: 71 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Hyperkalaemia, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Spironolactone

Other drugs received by patient possibly interacting with the suspect drug:
Enalapril Maleate
    Dosage: 2.5 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2000-01-01
    End date: 2008-08-26

Atacand
    Dosage: 8 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2004-01-01
    End date: 2008-08-28

Other drugs received by patient: Furosemide; Novorapid; Palladone; Bisoprolol CT; Isdn ^stada^; Lantus; Simvastatin; Lorazepam; Aspirin



Possible Spironolactone side effects in 78 year old male

Reported by a consumer/non-health professional from United States on 2012-02-08

Patient: 78 year old male

Reactions: Hyperkalaemia, Peritonitis Bacterial, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Altace
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    End date: 2009-09-09

Spironolactone
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Alcoholic Liver Disease
    End date: 2009-09-09

Altace
    Indication: Myocardial Ischaemia

Cotrim
    Dosage: 1960 mg, 5 times per week
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2009-08-20
    End date: 2009-09-09

Cotrim
    Indication: Peritonitis Bacterial

Other drugs received by patient: Propranolol; Glyceryl Trinitrate; Lactulose; Lansoprazole; Tamsulosin; Aspirin; Sucralfate; Allopurinol; Isosorbide Mononitrate; Novomix; Thiamine



Possible Spironolactone side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-07

Patient: male

Reactions: Hyperkalaemia, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Lantus
    Dosage: 40 iu, unk
    Indication: Diabetes Mellitus

Diovan

Spironolactone

Lasix
    Dosage: unk

Saxagliptin
    Dosage: unk
    Indication: Type 2 Diabetes Mellitus
    Start date: 2011-02-02
    End date: 2011-05-17

Blinded Therapy
    Dosage: 40 iu, unk
    Indication: Type 2 Diabetes Mellitus
    Start date: 2011-02-02
    End date: 2011-05-17

Metoprolol
    Dosage: unk

Verapamil HCL
    Dosage: unk

Other drugs received by patient: Ezetimibe; Acetylsalicylic Acid



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