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Spironolactone (Spironolactone) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (35)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Spironolactone where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 35   Next >>

Possible Spironolactone side effects in female

Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-08-20

Patient: female

Reactions: Hyponatraemia, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Escitalopram
    Dosage: 10 mg
    Administration route: Oral
    Indication: Depression
    End date: 2012-04-05

Spironolactone
    Dosage: 1 df
    Administration route: Oral
    Indication: Hypertension
    End date: 2012-04-05

Other drugs received by patient: Vitamin B-12; Ergocalciferol; Levothyroxine Sodium; Cordarone; Lercanidipine



Possible Spironolactone side effects in 62 year old male

Reported by a physician from Portugal on 2012-08-15

Patient: 62 year old male, weighing 70.0 kg (154.0 pounds)

Reactions: Product Quality Issue, Product Substitution Issue, Ischaemic Stroke, Drug Interaction, Hemiparesis, Hemianopia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Simvastatin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Carvedilol
    Dosage: 25 mg/day
    Administration route: Oral
    Indication: Hypertension

Captopril
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Potassium Chloride
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Acetylsalicylic Acid SRT
    Dosage: 300 mg, unk
    Administration route: Oral
    Indication: Transient Ischaemic Attack

Diazepam
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Warfarin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Nifedipine
    Dosage: 30 mg, 2x/day
    Indication: Product Used FOR Unknown Indication

Enalapril
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Amlodipine
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Enoxaparin
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Lisinopril Dihydrate; Irbesartan and Hydrochlorothiazide; Rilmenidine



Possible Spironolactone side effects in 66 year old male

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-05-30

Patient: 66 year old male

Reactions: Hepatic Encephalopathy, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Propranolol HCL
    Administration route: Oral
    Indication: Varices Oesophageal
    Start date: 2011-02-01

Furosemide
    Administration route: Oral
    Indication: Ascites
    Start date: 2011-02-28
    End date: 2011-05-23

Spironolactone
    Administration route: Oral
    Indication: Ascites
    Start date: 2011-04-29
    End date: 2011-05-23

Hyzaar
    Administration route: Oral
    Indication: Hypertension
    Start date: 2009-07-01
    End date: 2011-05-23

Other drugs received by patient: Simvastatin; Spironolactone



Possible Spironolactone side effects in 76 year old male

Reported by a consumer/non-health professional from United States on 2012-05-22

Patient: 76 year old male

Reactions: Breast Pain, Drug Interaction

Drug(s) suspected as cause:
Spironolactone

Other drugs received by patient possibly interacting with the suspect drug:
Clopidogrel
    Indication: Cerebrovascular Accident

Prilosec
    Administration route: Oral

Other drugs received by patient: Potassium Chloride; Furosemide; Hydralazine HCL; Cozaar; Lopressor



Possible Spironolactone side effects in 66 year old male

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-05-11

Patient: 66 year old male

Reactions: Hepatic Encephalopathy, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Furosemide
    Administration route: Oral
    Indication: Ascites
    Start date: 2011-02-28
    End date: 2011-05-23

Propranolol Hydrochloride
    Administration route: Oral
    Indication: Varices Oesophageal
    Start date: 2011-02-01

Hyzaar
    Administration route: Oral
    Indication: Hypertension
    Start date: 2009-07-01
    End date: 2011-05-23

Spironolactone
    Administration route: Oral
    Indication: Ascites
    Start date: 2011-04-29
    End date: 2011-05-23

Other drugs received by patient: Simvastatin; Spironolactone



Possible Spironolactone side effects in 60 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-04-24

Patient: 60 year old male, weighing 94.4 kg (207.7 pounds)

Reactions: Dyspnoea, Palpitations, International Normalised Ratio Decreased, Drug Interaction

Drug(s) suspected as cause:
Bumetanide

Spironolactone

Other drugs received by patient possibly interacting with the suspect drug:
Victoza
    Dosage: unk
    Start date: 2011-10-17
    End date: 2012-01-18

Warfarin Sodium

Other drugs received by patient: Bisoprolol Fumarate; Metformin HCL; Omeprazole; Atorvastatin; Candesartan Cilexetil



Possible Spironolactone side effects in 83 year old male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-04-05

Patient: 83 year old male

Reactions: Ventricular Extrasystoles, Nausea, Drug Interaction, Toxicity To Various Agents, Dyspnoea Exertional, Fatigue, Dizziness, Decreased Appetite, Cough

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Spironolactone

Other drugs received by patient possibly interacting with the suspect drug:
Digoxin
    Dosage: 0.125mg q.d.
    Administration route: Oral

Clarithromycin
    Administration route: Oral
    Indication: Pneumonia

Other drugs received by patient: Potassium; Bisoprolol Fumarate; Isosorbide Mononitrate; Furosemide; Pravastatin; Captopril



Possible Spironolactone side effects in 83 year old male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-04-03

Patient: 83 year old male

Reactions: Ventricular Extrasystoles, Nausea, Drug Interaction, Toxicity To Various Agents, Dyspnoea Exertional, Renal Impairment, Fatigue, Dizziness, Cough, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clarithromycin
    Dosage: 500 mg, bid
    Administration route: Oral
    Indication: Pneumonia

Spironolactone
    Dosage: 25 mg, qd
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Digoxin
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Spironolactone side effects in 76 year old female

Reported by a physician from Japan on 2012-03-14

Patient: 76 year old female

Reactions: Hyperkalaemia, Dehydration, Drug Interaction, Hypercalcaemia, Azotaemia

Drug(s) suspected as cause:
Spironolactone

Other drugs received by patient possibly interacting with the suspect drug:
Alfacalcidol
    Dosage: 1 ug, unk

Furosemide
    Dosage: 40 mg, 1x/day
    Administration route: Oral

Other drugs received by patient: Olmesartan



Possible Spironolactone side effects in male

Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-03-12

Patient: male

Reactions: Drug Ineffective, Gastrointestinal Disorder, Drug Interaction, Liver Disorder

Drug(s) suspected as cause:
Viagra
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-01

Spironolactone
    Dosage: 25 mg
    Indication: Product Used FOR Unknown Indication
    Start date: 2007-01-01

Other drugs received by patient: Levothyroxine Sodium



Possible Spironolactone side effects in 75 year old male

Reported by a physician from Norway on 2012-02-23

Patient: 75 year old male

Reactions: Peripheral Coldness, Confusional State, Metabolic Acidosis, Hyperkalaemia, Hypotension, Pulmonary Embolism, Bundle Branch Block Left, General Physical Health Deterioration, Drug Interaction, Cardiogenic Shock, Haemodialysis, Bradycardia, Septic Shock, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Ramipril
    Dosage: 10 mg (10 mg, 1 in 1 d)
    Indication: Cardiac Failure

Metoprolol Tartrate
    Dosage: 100 mg (100 mg, 1 in d)
    Indication: Cardiac Failure

Spironolactone
    Dosage: 25 mg (25 mg, 1 in1 d)
    Indication: Cardiac Failure

Other drugs received by patient: Bumetanid (Bumetanide); Digitoxin TAB



Possible Spironolactone side effects in 66 year old male

Reported by a physician from Sweden on 2012-02-23

Patient: 66 year old male

Reactions: Hyperkalaemia, Hyponatraemia, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Spironolactone

Other drugs received by patient possibly interacting with the suspect drug:
Amiodarone HCL
    Dosage: 200 mg, unk
    Administration route: Oral
    Start date: 2011-10-20

Other drugs received by patient: Losartan; Omeprazole; Pulmicort-100; Bisoprolol; Aspirin; Acetylcysteine



Possible Spironolactone side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-02-22

Patient: 65 year old female, weighing 64.0 kg (140.8 pounds)

Reactions: Drug Interaction, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zyvox
    Dosage: 600 mg, bid
    Administration route: Oral
    Indication: Intervertebral Discitis
    Start date: 2008-09-22
    End date: 2008-10-09

Zyvox
    Dosage: unk
    Start date: 2008-10-25
    End date: 2009-01-27

Amiodarone HCL
    Dosage: 200 mg, qd
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2008-09-01
    End date: 2008-10-10

Ramipril
    Dosage: 2.5 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Torsemide
    Dosage: 10 mg, bid
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29

Spironolactone
    Dosage: 100 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Xipamide
    Dosage: 10 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29
    End date: 2008-10-08

Other drugs received by patient: Metoprolol Tartrate and Hydrochlorothiazide; Digitoxin INJ; Acetaminophen; Enoxaparin Sodium; Omeprazole; Novalgin; Oxycodone HCL; Amitriptyline HCL; Simvastatin



Possible Spironolactone side effects in 72 year old male

Reported by a health professional (non-physician/pharmacist) from China on 2012-02-22

Patient: 72 year old male

Reactions: Syncope, Hyperkalaemia, Chest Pain, Drug Interaction, Sinus Arrest, Hyperhidrosis

Drug(s) suspected as cause:
Aceon
    Dosage: 4 mg, qd, oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-08-18
    End date: 2010-08-23

Spironolactone
    Dosage: 20 mg, qd, oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-08-18
    End date: 2010-08-23

Hydrochlorothiazide
    Dosage: 4. 25 mg, qd, oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-08-18
    End date: 2010-08-23

Potassium Chloride
    Dosage: 1 g, qd,. oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-08-18
    End date: 2010-08-23

Other drugs received by patient: Aspirin



Possible Spironolactone side effects in 75 year old male

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-02-21

Patient: 75 year old male

Reactions: Hyperkalaemia, Drug Interaction, Bradycardia, Cardiogenic Shock, Acute Prerenal Failure

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Spironolactone
    Dosage: 25 mg, daily
    Indication: Cardiac Failure

Metoprolol Tartrate
    Dosage: 100 mg, daily
    Indication: Cardiac Failure

Other drugs received by patient possibly interacting with the suspect drug:
Bumetanide
    Dosage: 1.5 mg, daily
    Indication: Cardiac Failure

Ramipril
    Dosage: 10 mg, daily
    Indication: Cardiac Failure

Other drugs received by patient: Digitoxin INJ



Possible Spironolactone side effects in 83 year old male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-02-15

Patient: 83 year old male

Reactions: Ventricular Extrasystoles, Renal Impairment, Malaise, Drug Interaction, Toxicity To Various Agents, Cough, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Captopril
    Dosage: 25 mg, po, bid
    Administration route: Oral
    Indication: Cardiac Disorder

Clarithromycin
    Dosage: 500 mg, bid, po
    Administration route: Oral
    Indication: Pneumonia

Spironolactone
    Dosage: 25 mg, po, qd
    Administration route: Oral
    Indication: Cardiac Disorder

Digoxin
    Dosage: 0.125 mg, po, qd
    Administration route: Oral
    Indication: Cardiac Disorder

Potassium Chloride
    Dosage: 20 mmol, qd

Other drugs received by patient: Furosemide; Isosorbide Mononitrate; Bisoprolol Fumarate; Pravastatin



Possible Spironolactone side effects in 78 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-02-15

Patient: 78 year old male

Reactions: Hyperkalaemia, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Ramipril
    Indication: Hypertension

Cotrim
    Dosage: 1960 mg, unk
    Administration route: Oral
    Indication: Peritonitis Bacterial
    Start date: 2009-08-20
    End date: 2009-09-09

Spironolactone
    Dosage: 100 mg, qid
    Administration route: Oral
    Indication: Alcoholic Liver Disease
    End date: 2009-09-09

Cotrim
    Indication: Prophylaxis

Ramipril
    Dosage: 2.5 mg, qd
    Administration route: Oral
    Indication: Myocardial Ischaemia
    End date: 2009-09-09

Other drugs received by patient: Novomix; Allopurinol; Lansoprazole; Thiamine HCL; Nitroglycerin; Isosorbide Mononitrate; Lactulose; Sucralfate; Aspirin; Propranolol; Tamsulosin HCL



Possible Spironolactone side effects in 83 year old male

Reported by a physician from Canada on 2012-02-15

Patient: 83 year old male

Reactions: Ventricular Extrasystoles, Nausea, Drug Interaction, Blood Potassium Increased, Toxicity To Various Agents, Dyspnoea Exertional, Fatigue, Malaise, Renal Impairment, Dizziness, Cough, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clarithromycin
    Dosage: 500 mg;po;bid
    Administration route: Oral
    Indication: Pneumonia

Potassium Chloride
    Dosage: 20 mmol;qd
    Indication: Cardiac Disorder

Digoxin
    Dosage: 0.125 mg;po;qd
    Administration route: Oral
    Indication: Cardiac Disorder

Spironolactone
    Dosage: 25 mg;po;qd
    Administration route: Oral
    Indication: Cardiac Disorder

Captopril
    Dosage: 25 mg;po;bid
    Administration route: Oral
    Indication: Cardiac Disorder

Other drugs received by patient: Pravastatin; Furosemide; Isosorbide Mononitrate; Bisoprolol Fumarate



Possible Spironolactone side effects in 71 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-02-13

Patient: 71 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Hyperkalaemia, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Spironolactone

Other drugs received by patient possibly interacting with the suspect drug:
Enalapril Maleate
    Dosage: 2.5 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2000-01-01
    End date: 2008-08-26

Atacand
    Dosage: 8 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2004-01-01
    End date: 2008-08-28

Other drugs received by patient: Furosemide; Novorapid; Palladone; Bisoprolol CT; Isdn ^stada^; Lantus; Simvastatin; Lorazepam; Aspirin



Possible Spironolactone side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-02-08

Patient: 65 year old female

Reactions: Vomiting, Nausea, Oedema Peripheral, Tongue DRY, Drug Interaction, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Spironolactone
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Xipamide
    Dosage: 10 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29
    End date: 2008-10-08

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Indication: Intervertebral Discitis
    Start date: 2008-09-22
    End date: 2008-10-09

Amiodarone HCL
    Dosage: 200 mg, 1x/day
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2008-09-01
    End date: 2008-10-10

Torsemide
    Dosage: 10 mg, 2x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2009-07-29

Altace
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Start date: 2008-10-25
    End date: 2009-01-27

Other drugs received by patient: Amitriptyline; Phenprocoumon; Oxycodone; Novalgin; Paracetamol; Enoxaparin Sodium; Digitoxin; Omeprazole; Metoprolol Tartrate and Hydrochlorothiazide; Simvastatin



Possible Spironolactone side effects in 78 year old male

Reported by a consumer/non-health professional from United States on 2012-02-08

Patient: 78 year old male

Reactions: Hyperkalaemia, Peritonitis Bacterial, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Altace
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    End date: 2009-09-09

Spironolactone
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Alcoholic Liver Disease
    End date: 2009-09-09

Altace
    Indication: Myocardial Ischaemia

Cotrim
    Dosage: 1960 mg, 5 times per week
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2009-08-20
    End date: 2009-09-09

Cotrim
    Indication: Peritonitis Bacterial

Other drugs received by patient: Propranolol; Glyceryl Trinitrate; Lactulose; Lansoprazole; Tamsulosin; Aspirin; Sucralfate; Allopurinol; Isosorbide Mononitrate; Novomix; Thiamine



Possible Spironolactone side effects in 66 year old male

Reported by a physician from Sweden on 2012-02-03

Patient: 66 year old male

Reactions: Hyperkalaemia, Drug Interaction, Hyponatraemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Spironolactone

Other drugs received by patient possibly interacting with the suspect drug:
Amiodarone HCL
    Dosage: 200 mg daily
    Administration route: Oral
    Start date: 2011-10-20

Other drugs received by patient: Pulmicort-100; Bisoprolol; Acetylcysteine; Omeprazole; Aspirin; Losartan



Possible Spironolactone side effects in 75 year old male

Reported by a physician from Norway on 2012-01-30

Patient: 75 year old male

Reactions: Peripheral Coldness, Confusional State, Hyperkalaemia, Drug Interaction, Acute Left Ventricular Failure, Electrocardiogram QRS Complex Prolonged, Hypoxia, Renal Failure Acute, Hypovolaemia, Mitral Valve Disease, Metabolic Acidosis, General Physical Health Deterioration, Bundle Branch Block Left, Cardioactive Drug Level Increased, Cardiogenic Shock, Haemodialysis, Electrocardiogram T Wave Amplitude Increased, Renal Failure, Hypophagia, Ejection Fraction Decreased, Depressed Level of Consciousness, Fluid Intake Reduced, Bradycardia, Hypertension

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Ramipril
    Dosage: 10 mg (10 mg, 1 in 1 d),
    Indication: Cardiac Failure

Metoprolol Tartrate
    Dosage: 100 mg (100 mg, 1 in 1 d),
    Indication: Cardiac Failure

Spironolactone
    Dosage: 25 mg (25 mg, 1 in 1 d),
    Indication: Cardiac Failure

Other drugs received by patient: Digitoxin INJ; Bumetanid (Bumetanide)



Possible Spironolactone side effects in 78 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-01-27

Patient: 78 year old male

Reactions: Hyperkalaemia, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Spironolactone

Other drugs received by patient possibly interacting with the suspect drug:
Ramipril
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    End date: 2009-09-09

Cotrim
    Dosage: 1960 mg, 5x weekly, cyclic
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2009-08-20
    End date: 2009-09-09

Ramipril
    Indication: Myocardial Ischaemia

Cotrim
    Indication: Peritonitis Bacterial

Other drugs received by patient: Sucralfate; Lactulose; Novolog MIX 70 / 30; Propranolol; Isosorbide Mononitrate; Lansoprazole; Tamsulosin; Thiamine; Acetylsalicylic Acid; Allopurinol; Glyceryl Trinitrate



Possible Spironolactone side effects in 78 year old male

Reported by a consumer/non-health professional from United States on 2012-01-27

Patient: 78 year old male

Reactions: Hyperkalaemia, Peritonitis Bacterial, Drug Interaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Spironolactone
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Alcoholic Liver Disease
    End date: 2009-09-09

Cotrim
    Dosage: 1960 mg, 5 times per week
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2009-08-20
    End date: 2009-09-09

Altace
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    End date: 2009-09-09

Cotrim
    Indication: Peritonitis Bacterial

Altace
    Indication: Myocardial Ischaemia

Other drugs received by patient: Propranolol; Aspirin; Glyceryl Trinitrate; Thiamine; Allopurinol; Lansoprazole; Tamsulosin; Lactulose; Novolog MIX 70 / 30; Isosorbide Mononitrate; Sucralfate



Possible Spironolactone side effects in 65 year old female

Reported by a consumer/non-health professional from Germany on 2012-01-27

Patient: 65 year old female

Reactions: Vomiting, Nausea, Oedema Peripheral, Tongue DRY, Drug Interaction, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Torsemide
    Dosage: 10 mg, 2x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2009-07-29

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Indication: Intervertebral Discitis
    Start date: 2008-09-22
    End date: 2008-10-09

Zyvox
    Dosage: 600 mg, 2x/day
    Administration route: Oral
    Start date: 2008-10-25
    End date: 2009-01-27

Altace
    Dosage: 2.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Spironolactone
    Dosage: 100 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-09-01
    End date: 2008-10-09

Amiodarone HCL
    Dosage: 200 mg, 1x/day
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2008-09-01
    End date: 2008-10-10

Xipamide
    Dosage: 10 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-07-29
    End date: 2008-10-08

Other drugs received by patient: Paracetamol; Phenprocoumon; Metoprolol Tartrate and Hydrochlorothiazide; Omeprazole; Enoxaparin Sodium; Oxycodone; Digitoxin; Novalgin; Amitriptyline; Simvastatin



Possible Spironolactone side effects in 85 year old male

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-01-24

Patient: 85 year old male

Reactions: Renal Failure, Hyperkalaemia, Drug Interaction

Drug(s) suspected as cause:
Cozaar
    Administration route: Oral
    Indication: Cardiac Failure
    Start date: 2011-05-29
    End date: 2011-08-10

Spironolactone
    Administration route: Oral
    Indication: Cardiac Failure
    Start date: 2009-09-08
    End date: 2011-08-10

Other drugs received by patient: Furosemide; Tiotropium Bromide; Gabapentin; Acenocoumarol



Possible Spironolactone side effects in 75 year old male

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-01-23

Patient: 75 year old male

Reactions: Hyperkalaemia, Drug Interaction, Bradycardia, Cardiogenic Shock, Acute Prerenal Failure

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Spironolactone
    Dosage: 25 mg, daily
    Indication: Cardiac Failure

Metoprolol
    Dosage: 100 mg, daily
    Indication: Cardiac Failure

Ramipril
    Dosage: 10 mg, daily
    Indication: Cardiac Failure

Other drugs received by patient possibly interacting with the suspect drug:
Bumetanide
    Dosage: 1.5 mg, daily
    Indication: Cardiac Failure

Other drugs received by patient: Digitoxin



Possible Spironolactone side effects in 73 year old male

Reported by a health professional (non-physician/pharmacist) from Austria on 2011-12-15

Patient: 73 year old male

Reactions: Renal Injury, Hyperkalaemia, Drug Interaction, Toxicity To Various Agents, Cardiac Arrest

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Furosemide
    Dosage: 30 mg, qd
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Dosage: 100 mg, qd
    Indication: Product Used FOR Unknown Indication

Amiloride HCL and Hydrochlorothiazide
    Dosage: 50/5 mg, qd
    Indication: Product Used FOR Unknown Indication

Enalapril Maleate
    Dosage: 10 mg, qd
    Indication: Product Used FOR Unknown Indication



Possible Spironolactone side effects in 71 year old female

Reported by a consumer/non-health professional from United States on 2011-11-21

Patient: 71 year old female

Reactions: Ventricular Extrasystoles, Dyspnoea, Eye Oedema, Drug Interaction, Mental Impairment, Malaise, Blood Electrolytes Abnormal, Diarrhoea, Visual Impairment, Oedema, Nasal Disorder, Blood Creatinine Increased

Drug(s) suspected as cause:
Potassium Chloride
    Indication: Product Used FOR Unknown Indication

Bumetanide
    Indication: Product Used FOR Unknown Indication

Spironolactone
    Indication: Product Used FOR Unknown Indication

Lorazepam
    Indication: Product Used FOR Unknown Indication

Metolazone
    Indication: Product Used FOR Unknown Indication

Diltiazem
    Indication: Product Used FOR Unknown Indication

Metoprolol Tartrate
    Indication: Product Used FOR Unknown Indication

Folic Acid
    Indication: Product Used FOR Unknown Indication

Latanoprost
    Indication: Product Used FOR Unknown Indication

Cetirizine
    Indication: Product Used FOR Unknown Indication

Simvastatin
    Indication: Product Used FOR Unknown Indication

Tikosyn
    Indication: Atrial Fibrillation

Other drugs received by patient: Warfarin Sodium



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