This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Simcor (Simvastatin / Niacin) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (1205)
Reports by Reaction Type
Flushing (690),
Pruritus (270),
Feeling Hot (207),
Paraesthesia (202),
Erythema (184),
Skin Burning Sensation (110),
Burning Sensation (65),
Blood Glucose Increased (54),
Dizziness (44),
Myalgia (41),
Hot Flush (37),
Pain in Extremity (29)
Below are a few examples of reports where side effects / adverse reactions may be related to Simcor (Simvastatin / Niacin). For a complete list or a specific selection of reports, please use the links above.
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: female
Reactions: Nephrolithiasis, Urinary Tract Infection
Drug(s) suspected as cause:
Simcor
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-15
Patient: female, weighing 104.4 kg (229.7 pounds)
Reactions: Myocardial Infarction, Deep Vein Thrombosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Simcor
Dosage: 500/20
Indication: Blood Triglycerides Increased
Start date: 2011-03-22
End date: 2012-05-30
Simcor
Indication: Blood Cholesterol Increased
Other drugs received by patient: Protonix; Plavix; Ranolazine; Toprol-XL
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-15
Patient: female, weighing 104.4 kg (229.7 pounds)
Reactions: Flushing, Postoperative Adhesion, Pruritus, Chest Pain, Erythema, Paraesthesia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Niaspan
Indication: Blood Cholesterol Increased
Niaspan
Indication: Blood Triglycerides Increased
Start date: 2012-05-30
Simcor
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Protonix; Toprol-XL; Effient; Crestor; Ranolazine
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-10
Patient: female, weighing 104.4 kg (229.7 pounds)
Reactions: Flushing, Pruritus, Chest Pain, Erythema, Paraesthesia, Excessive Granulation Tissue
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Niaspan
Indication: Blood Cholesterol Increased
Niaspan
Indication: Blood Triglycerides Increased
Start date: 2012-05-30
Simcor
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Toprol-XL; Ranolazine; Crestor; Protonix; Effient
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-10
Patient: female, weighing 104.4 kg (229.7 pounds)
Reactions: Myocardial Infarction, Deep Vein Thrombosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Simcor
Dosage: 500/20
Indication: Blood Triglycerides Increased
Start date: 2011-03-22
End date: 2012-05-30
Simcor
Indication: Blood Cholesterol Increased
Other drugs received by patient: Protonix; Toprol-XL; Ranolazine; Plavix
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-09
Patient: female, weighing 105.3 kg (231.7 pounds)
Reactions: Flushing, Knee Operation, Skin Burning Sensation
Drug(s) suspected as cause:
Simcor
Dosage: 750/20mg at bedtime
Start date: 2012-07-29
Simcor
Dosage: 750/20mg at bedtime
Indication: High Density Lipoprotein Decreased
Start date: 2011-07-01
End date: 2012-06-06
Other drugs received by patient: Ziac; Hydrocodone Bitartrate; Aspirin
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: female, weighing 63.6 kg (139.8 pounds)
Reactions: Flushing, Burning Sensation, Pruritus, Gastric Ulcer
Drug(s) suspected as cause:
Niaspan
Indication: Product Used FOR Unknown Indication
Simcor
Indication: Product Used FOR Unknown Indication
End date: 2010-01-01
Other drugs received by patient: Metoprolol Tartrate; Omeprazole; Stool Softener; Fosamax; Vitamin D; Fish OIL; Ambien; Levothyroxine Sodium; Calcium; Glimepiride; Victoza; Lovastatin
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 81.7 kg (179.8 pounds)
Reactions: Flushing, Pruritus, Feeling Hot, Erythema, Sleep Apnoea Syndrome, Hepatic Enzyme Increased, Hepatic Steatosis
Drug(s) suspected as cause:
Niaspan
Indication: Blood Triglycerides Increased
Niaspan
Start date: 2011-03-01
Simcor
Dosage: 1000mg/20mg
Indication: Blood Triglycerides Increased
Other drugs received by patient: Lovaza
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: female
Reactions: Flushing, Skin Burning Sensation, Erythema
Drug(s) suspected as cause:
Niaspan
Dosage: at bed time
Indication: Product Used FOR Unknown Indication
Simcor
Dosage: 500/20mg at bedtime
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2012-07-01
Other drugs received by patient: Aspirin; Other Unknown Medications
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 88.5 kg (194.8 pounds)
Reactions: Flushing, Hepatic Enzyme Increased
Drug(s) suspected as cause:
Niaspan
Indication: Blood Triglycerides Increased
Start date: 2011-10-01
Simcor
Simcor
Indication: Product Used FOR Unknown Indication
Start date: 2008-11-01
Other drugs received by patient: Aspirin; Benicar; Herbal Supplements; Avodart
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 104.4 kg (229.7 pounds)
Reactions: Gastrooesophageal Reflux Disease
Drug(s) suspected as cause:
Niaspan
Indication: High Density Lipoprotein Decreased
Simcor
Indication: Blood Triglycerides Abnormal
Other drugs received by patient: Other Unknown Medication; Unknown Blood Pressure Medication
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 102.2 kg (224.7 pounds)
Reactions: Flushing, Dysphagia, Gastric Ulcer
Drug(s) suspected as cause:
Niaspan
Indication: High Density Lipoprotein Decreased
Niaspan
Indication: LOW Density Lipoprotein Increased
Simcor
Dosage: 100mg/40mg at hour of sleep daily
Administration route: Oral
Indication: LOW Density Lipoprotein Increased
Start date: 2009-01-01
Simcor
Indication: High Density Lipoprotein Decreased
Other drugs received by patient: Metoprolol Tartrate; Aspirin
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: female, weighing 97.6 kg (214.7 pounds)
Reactions: Weight Increased
Drug(s) suspected as cause:
Niaspan
Indication: Product Used FOR Unknown Indication
Start date: 2010-12-01
End date: 2011-02-01
Simcor
Indication: Product Used FOR Unknown Indication
Start date: 2011-03-01
Other drugs received by patient: Atenolol
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male
Reactions: Musculoskeletal Stiffness, Asthenia, Somnolence
Drug(s) suspected as cause:
Fenofibrate
Indication: Product Used FOR Unknown Indication
Niaspan
Indication: Blood Triglycerides Increased
Simcor
Indication: Blood Triglycerides Increased
Other drugs received by patient: Fluticasone Furoate; Simvastatin
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 77.2 kg (169.8 pounds)
Reactions: Asthma, Flushing, Pruritus, Dizziness, Erythema
Drug(s) suspected as cause:
Niaspan
Indication: Blood Triglycerides Increased
Start date: 2002-05-01
Niaspan
Indication: LOW Density Lipoprotein Increased
Niaspan
Dosage: every night
Indication: High Density Lipoprotein Decreased
End date: 2012-03-01
Simcor
Dosage: 1000/20mg (2 pills) at night
Indication: Blood Triglycerides Increased
Start date: 2012-03-01
Simcor
Indication: High Density Lipoprotein Decreased
Simcor
Indication: LOW Density Lipoprotein Increased
Other drugs received by patient: Lovaza; Fluticasone Propionate; Seasonal Rhinocort; Allegra; Lipitor; Aspirin
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: female, weighing 76.3 kg (167.8 pounds)
Reactions: Blood Cholesterol Abnormal, Vitamin D Deficiency, Flushing, Pruritus, Increased Tendency To Bruise, Erythema, Muscle Spasms
Drug(s) suspected as cause:
Aspirin
Dosage: not reported
Indication: Prophylaxis
End date: 2010-01-01
Niacin
Dosage: not reported
Indication: Blood Cholesterol Abnormal
Niaspan
Dosage: at bedtime
Administration route: Oral
Indication: High Density Lipoprotein Decreased
Start date: 2011-10-01
Niaspan
Dosage: interrupted
Indication: High Density Lipoprotein Decreased
Start date: 2010-01-01
End date: 2011-01-01
Simcor
Dosage: 500/20mg at bedtime
Administration route: Oral
Indication: High Density Lipoprotein Decreased
Start date: 2011-04-01
Simvastatin
Dosage: not reported
Indication: High Density Lipoprotein Decreased
Start date: 2010-01-01
Other drugs received by patient: Folic Acid; Tramadol HCL; Diovan HCT; Lasix; Alpha Lipoic Acid
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: female, weighing 69.0 kg (151.8 pounds)
Reactions: Blood Bilirubin Increased, Nausea
Drug(s) suspected as cause:
Niaspan
Indication: Blood Cholesterol Increased
Simcor
Dosage: 500/20 mg at bedtime
Indication: Blood Cholesterol Increased
Start date: 2011-01-01
Simcor
Other drugs received by patient: Metformin Hydrochloride
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male
Reactions: Flushing, Pruritus
Drug(s) suspected as cause:
Niaspan
Indication: Product Used FOR Unknown Indication
Simcor
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Nexium; Benadryl; Aspirin; Blood Pressure Medication
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 115.3 kg (253.7 pounds)
Reactions: Flushing, Pruritus, Feeling Hot, Erythema, Paraesthesia
Drug(s) suspected as cause:
Niaspan
Dosage: at bedtime
Administration route: Oral
Indication: Blood Cholesterol Increased
Start date: 2010-10-01
Simcor
Dosage: 500/40mg at bedtime
Administration route: Oral
Indication: Blood Cholesterol Increased
Start date: 2009-10-01
End date: 2010-10-01
Other drugs received by patient: Multi-Vitamin; Simvastatin
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: female, weighing 90.8 kg (199.8 pounds)
Reactions: Feeling Hot
Drug(s) suspected as cause:
Niaspan
Indication: Blood Cholesterol Increased
Start date: 2012-03-01
End date: 2012-05-16
Simcor
Indication: Blood Cholesterol
Other drugs received by patient: Zocor; Aspirin
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 86.3 kg (189.8 pounds)
Reactions: Flushing, Feeling Hot
Drug(s) suspected as cause:
Niaspan
Indication: Blood Triglycerides Increased
Start date: 2010-01-01
End date: 2010-11-01
Simcor
Indication: Blood Triglycerides Increased
Other drugs received by patient: Fish OIL; Multi-Vitamins
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male
Reactions: Flushing, Pruritus
Drug(s) suspected as cause:
Niaspan
Indication: Product Used FOR Unknown Indication
Simcor
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Aspirin
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male
Reactions: Flushing, Pruritus, Feeling Hot
Drug(s) suspected as cause:
Niaspan
Indication: Product Used FOR Unknown Indication
Simcor
Dosage: 1000/40mg at bedtime
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Aspirin; Vitamin D; Lovaza
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: female, weighing 66.3 kg (145.8 pounds)
Reactions: Flushing, Pruritus, Paraesthesia Oral, Joint Swelling, Constipation
Drug(s) suspected as cause:
Crestor
Crestor
Indication: Product Used FOR Unknown Indication
Start date: 2011-01-01
End date: 2011-01-01
Lipitor
Indication: Product Used FOR Unknown Indication
Start date: 2011-01-01
Niaspan
Indication: LOW Density Lipoprotein Increased
Start date: 2011-01-01
End date: 2011-01-01
Niaspan
Dosage: at hs
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-01-01
Simcor
Indication: Product Used FOR Unknown Indication
Start date: 2011-01-01
End date: 2011-01-01
Other drugs received by patient: Verapamil; Aspirin; Latanoprost; Triamterene; Synthroid; Femhrt
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 81.7 kg (179.8 pounds)
Reactions: Piloerection, Sleep Disorder, Diarrhoea, Pain, Headache, Feeling Cold
Drug(s) suspected as cause:
Niaspan
Dosage: at bedtime, will restart once prescription is filled
Indication: Blood Cholesterol Increased
Start date: 2009-11-01
End date: 2011-08-01
Simcor
Dosage: will stop once niaspan is refilled
Indication: Blood Cholesterol Increased
Start date: 2011-08-01
Other drugs received by patient: Aspirin; Losartan Potassium; Lipitor
Possible Simcor side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: female, weighing 54.5 kg (119.9 pounds)
Reactions: Flushing, Viral Infection, Nausea, Parkinson's Disease, Skin Burning Sensation, Tremor
Drug(s) suspected as cause:
Niaspan
Dosage: 500mg at bedtime
Indication: Blood Cholesterol
Start date: 2010-04-01
Niaspan
Indication: Familial Risk Factor
Simcor
Dosage: 1000mg/20mg at bedtime
Indication: Blood Cholesterol
Start date: 2010-01-01
End date: 2010-01-01
Simcor
Dosage: 1000mg/20mg at bedtime
Indication: Familial Risk Factor
Start date: 2010-01-01
Other drugs received by patient: Carbidopa and Levodopa; Aspirin; Aspirin
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 73.5 kg (161.8 pounds)
Reactions: Flushing, Pruritus, Feeling Hot, Erythema
Drug(s) suspected as cause:
Niaspan
Dosage: at bedtime
Indication: Product Used FOR Unknown Indication
Start date: 2010-06-01
Simcor
Dosage: 1000/20 at bedtime
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Aspirin; Zytec; Fish OIL; MVT
Possible Simcor side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: male, weighing 109.0 kg (239.7 pounds)
Reactions: Blood Glucose Increased
Drug(s) suspected as cause:
Niaspan
Dosage: at bedtime
Administration route: Oral
Indication: High Density Lipoprotein Decreased
Start date: 2010-01-01
Simcor
Dosage: 500/20 mg every hs
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2009-06-01
Other drugs received by patient: Vitamin D; Lisinopril; Metformin Hydrochloride
Possible Simcor side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-11
Patient: male, weighing 141.2 kg (310.6 pounds)
Reactions: Blood Triglycerides Increased, High Density Lipoprotein Decreased, Inguinal Hernia
Drug(s) suspected as cause:
Anesthesia
Indication: Surgery
Start date: 2011-10-27
End date: 2011-10-27
Simcor
Dosage: 1000mg/40mg
Indication: Dyslipidaemia
Start date: 2010-09-30
End date: 2011-09-09
Simcor
Possible Simcor side effects in female
Reported by a physician from United States on 2012-06-26
Patient: female, weighing 104.4 kg (229.7 pounds)
Reactions: Osteoarthritis
Drug(s) suspected as cause:
Simcor
Dosage: 500/20mg 2 tablets qhs
Indication: Hyperlipidaemia
Start date: 2010-05-01
Simcor
Dosage: 500/20mg 2 tablets qhs
End date: 2012-01-17
Other drugs received by patient: Antihistamine OTC; Losartan Potassium; Prilosec; Aspirin; Centralline; Valtrex
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