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Sevoflurane (Sevoflurane) - Cardiac Arrest - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Cardiac Arrest (20)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Sevoflurane where reactions include cardiac arrest. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Sevoflurane side effects in 18 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-07

Patient: 18 year old male

Reactions: Bloody Discharge, Puncture Site Haemorrhage, Haemorrhage, Coagulopathy, Hyperthermia Malignant, Ventricular Arrhythmia, Organ Failure, Cardiac Failure, NO Therapeutic Response, Pulmonary Oedema, Cardiac Arrest

Adverse event resulted in: death

Drug(s) suspected as cause:
Dantrolene Sodium
    Dosage: 2.5 mg/kg, initial dose
    Indication: Hyperthermia Malignant

Succinylcholine Chloride

Sevoflurane
    Dosage: gas anesthetic
    Indication: Anaesthesia



Possible Sevoflurane side effects in male

Reported by a physician from United States on 2012-07-10

Patient: male

Reactions: Haemorrhage, NO Therapeutic Response, Coagulopathy, Hyperthermia Malignant, Ventricular Arrhythmia, Pulmonary Oedema, Cardiac Arrest, Organ Failure

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Sevoflurane
    Dosage: gas anesthetic
    Indication: Anaesthesia

Dantrolene Sodium
    Dosage: see image
    Indication: Hyperthermia Malignant



Possible Sevoflurane side effects in female

Reported by a physician from France on 2012-07-03

Patient: female, weighing 70.0 kg (154.0 pounds)

Reactions: Ventricular Tachycardia, Cardiac Arrest

Adverse event resulted in: death

Drug(s) suspected as cause:
Nefopam Mylan
    Dosage: 20 mg daily dose
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-04-18
    End date: 2012-04-18

Propofol
    Dosage: 170 mg daily dose
    Indication: Induction of Anaesthesia
    Start date: 2012-04-18
    End date: 2012-04-18

Ephedrine Aguettant
    Dosage: 6 mg daily dose
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-04-18
    End date: 2012-04-18

Droperidol
    Dosage: 1.25 mg daily dose
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-04-18
    End date: 2012-04-18

Sevoflurane
    Indication: Induction of Anaesthesia
    Start date: 2012-04-18
    End date: 2012-04-18

Cefazolin
    Dosage: 2 gram daily dose
    Indication: Premedication
    Start date: 2012-04-18
    End date: 2012-04-18

Acetaminophen
    Dosage: 1 gram daily dose
    Indication: Induction of Anaesthesia
    Start date: 2012-04-18
    End date: 2012-04-18

Ketamine HCL
    Dosage: 15 mg daily dose
    Indication: Induction of Anaesthesia
    Start date: 2012-04-18
    End date: 2012-04-18

Midazolam
    Dosage: 1.5 mg daily dose
    Indication: Induction of Anaesthesia
    Start date: 2012-04-18
    End date: 2012-04-18

Nimbex
    Indication: Induction of Anaesthesia
    Start date: 2012-04-18
    End date: 2012-04-18

Sufentanil Renaudin
    Dosage: 50 mcg daily dose
    Indication: Induction of Anaesthesia
    Start date: 2012-04-18
    End date: 2012-04-18

Other drugs received by patient: Carteolol Hydrochloride; Omeprazole; Ibuprofen; Acetaminophen and Tramadol HCL



Possible Sevoflurane side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-21

Patient: male, weighing 100.0 kg (220.0 pounds)

Reactions: Post Procedural Complication, Atrioventricular Block Complete, Drug Interaction, Continuous Haemodiafiltration, Nodal Rhythm, Atrial Fibrillation, Toxicity To Various Agents, Anaesthetic Complication Cardiac, Sedation, Glossoptosis, Depressed Level of Consciousness, Sinus Arrest, Cardiac Arrest, Oxygen Saturation Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Nicardipine HCL
    Dosage: 4.16 ug/kg/min
    Indication: Hypertension

Nicardipine HCL
    Dosage: 4.16 ug/kg/min
    Indication: Tachycardia

Sevoflurane
    Dosage: unknown
    Indication: Maintenance of Anaesthesia

Diltiazem
    Dosage: 4.5 ug/kg/min
    Indication: Hypertension

Midazolam
    Dosage: 3 mg/hour, intravenous
    Indication: Sedation

Other drugs received by patient: Vecuronium Bromide; Thiamylal Sodium; Fentanyl Citrate



Possible Sevoflurane side effects in 39 year old male

Reported by a individual with unspecified qualification from Japan on 2012-06-05

Patient: 39 year old male

Reactions: Drug Interaction, Sinus Arrest, Toxicity To Various Agents, Cardiac Arrest

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Nicardipine Hydrochloride Injection
    Dosage: 4.17 ug/kg/min; intravenous drip
    Indication: Hypertension

Midazolam
    Dosage: 3 mg/hour intravenous drip
    Indication: Sedation

Sevoflurane
    Indication: Anaesthesia

Diltiazem
    Dosage: 4.5 ug/kg/min; intravenous drip
    Indication: Tachycardia

Other drugs received by patient: Fentanyl; Thiamylal Sodium; Vecuronium Bromide



Possible Sevoflurane side effects in male

Reported by a physician from Japan on 2012-04-18

Patient: male, weighing 100.0 kg (220.0 pounds)

Reactions: Overdose, Drug Interaction, Sinus Arrest, Toxicity To Various Agents, Cardiac Arrest

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Sevoflurane

Other drugs received by patient possibly interacting with the suspect drug:
Diltiazem HCL
    Dosage: 4.5 mcg/kg/min
    Indication: Hypertension
    Start date: 2010-05-25
    End date: 2010-05-26

Midazolam HCL
    Dosage: 3 mg/hr
    Indication: Sedative Therapy
    Start date: 2010-05-25
    End date: 2010-05-26

Nicardipine HCL
    Dosage: 4.17 mcg/kg/min
    Indication: Hypertension
    Start date: 2010-05-25
    End date: 2010-05-26

Nicardipine HCL
    Indication: Tachycardia

Diltiazem HCL
    Indication: Tachycardia

Other drugs received by patient: Thiamylal Sodium; Fentanyl; Oxygen; Vecuronium Bromide



Possible Sevoflurane side effects in 35 year old female

Reported by a health professional (non-physician/pharmacist) on 2012-04-10

Patient: 35 year old female

Reactions: Hypotension, Anaesthetic Complication Cardiac, Long QT Syndrome, Ventricular Tachycardia, Ventricular Fibrillation, Bradycardia, Apnoea, Cardiac Arrest

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Sevoflurane
    Dosage: inhalation
    Indication: Anaesthesia

Epinephrine
    Dosage: (1 mg), intravenous bolus, unknown (4 total), intravenous bolus
    Indication: Anaesthesia

Epinephrine
    Dosage: (1 mg), intravenous bolus, unknown (4 total), intravenous bolus
    Indication: Ventricular Fibrillation

Xylocaine W / Epinephrine
    Dosage: (y), nasal
    Indication: Anaesthesia

Ondansetron Hydrochloride
    Dosage: (4 mg), intravenous
    Indication: Product Used FOR Unknown Indication

Amiodarone HCL
    Dosage: (300 mg), unknown
    Indication: Ventricular Fibrillation

Amiodarone HCL
    Dosage: (300 mg), unknown
    Indication: Hypotension

Cocaine (Cocaine)
    Dosage: (250 mg), nasal
    Indication: Anaesthesia

Cocaine (Cocaine)
    Dosage: (250 mg), nasal
    Indication: Nasal Septal Operation

Other drugs received by patient: Oxygen (Oxygen); Atropine; Diclofenac Sodium; Nitrous Oxide W / Oxygen; Lidocaine; Propofol; Sodium Bicarbonate IN Plastic Container; Fentanyl



Possible Sevoflurane side effects in male

Reported by a physician from Japan on 2012-04-06

Patient: male, weighing 105.0 kg (231.0 pounds)

Reactions: Overdose, Drug Interaction, Sinus Arrest, Cardiac Arrest

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Sevoflurane

Other drugs received by patient possibly interacting with the suspect drug:
Midazolam HCL
    Dosage: continuous
    Indication: Subarachnoid Haemorrhage
    Start date: 2010-05-25
    End date: 2010-05-26

Diltiazem HCL
    Dosage: continuous
    Indication: Subarachnoid Haemorrhage
    Start date: 2010-05-25
    End date: 2010-05-26

Nicardipine HCL
    Dosage: continuous
    Indication: Subarachnoid Haemorrhage
    Start date: 2010-05-25
    End date: 2010-05-26

Other drugs received by patient: Thiamylal Sodium; Fentanyl Citrate; Vecuronium Bromide



Possible Sevoflurane side effects in male

Reported by a physician from Japan on 2012-04-06

Patient: male, weighing 105.0 kg (231.0 pounds)

Reactions: Overdose, Drug Interaction, Sinus Arrest, Cardiac Arrest

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Sevoflurane

Other drugs received by patient possibly interacting with the suspect drug:
Midazolam HCL
    Dosage: continuous
    Indication: Subarachnoid Haemorrhage
    Start date: 2010-05-25
    End date: 2010-05-26

Diltiazem HCL
    Dosage: continuous
    Indication: Subarachnoid Haemorrhage
    Start date: 2010-05-25
    End date: 2010-05-26

Nicardipine HCL
    Dosage: continuous
    Indication: Subarachnoid Haemorrhage
    Start date: 2010-05-25
    End date: 2010-05-26

Other drugs received by patient: Vecuronium Bromide; Fentanyl; Thiamylal Sodium



Possible Sevoflurane side effects in 35 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-04-03

Patient: 35 year old female

Reactions: Ventricular Tachycardia, Hypotension, Bradycardia, Ventricular Fibrillation, Cardiac Arrest, Apnoea, Long QT Syndrome

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Amiodarone HCL
    Dosage: 300 mg, single
    Indication: Ventricular Fibrillation

Cocaine
    Indication: Nasal Septal Operation

Cocaine
    Dosage: 250 mg, single
    Indication: Anaesthesia

Amiodarone HCL
    Indication: Hypotension

Sevoflurane
    Dosage: 3%
    Indication: Anaesthesia

Epinephrine
    Dosage: 1mg intravenous bolus x 4
    Indication: Ventricular Fibrillation

Epinephrine
    Indication: Anaesthesia

Ondansetron
    Dosage: 4 mg, single

Lidocaine and Epinephrine
    Dosage: [lidocaine 100mg]/[epinephrine 60mcg]
    Indication: Anaesthesia

Other drugs received by patient: Lidocaine; Nitrous Oxide; Propofol; Sodium Bicarbonate; Atropine; Diclofenac; Oxygen; Fentanyl



Possible Sevoflurane side effects in female

Reported by a physician from France on 2012-03-05

Patient: female, weighing 13.0 kg (28.6 pounds)

Reactions: Acute Pulmonary Oedema, Williams Syndrome, Supravalvular Aortic Stenosis, Hypercapnia, Cardiac Failure Acute, Pulmonary Haemorrhage, Ventricular Hypertrophy, Heart Rate Decreased, Electrocardiogram QRS Complex Prolonged, Cyanosis, Pulse Absent, Oxygen Saturation Immeasurable, Bradycardia, Heart Disease Congenital, Blood Pressure Immeasurable, Cardiac Arrest

Adverse event resulted in: death

Drug(s) suspected as cause:
Sevoflurane
    Indication: Anaesthesia
    Start date: 2011-04-05
    End date: 2011-04-05

Fluorescein Sodium
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-04-05
    End date: 2011-04-05

Phenylephrine HCL
    Dosage: collyre 10% one drop in each eye
    Indication: Mydriasis
    Start date: 2011-04-05
    End date: 2011-04-05

Other drugs received by patient: Tropicamide; Benoxinate Hydrochloride; B66 500ml; Atarax



Possible Sevoflurane side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-03-05

Patient: female, weighing 13.0 kg (28.6 pounds)

Reactions: Acute Pulmonary Oedema, Aortic Stenosis, Conduction Disorder, Carotid Pulse Abnormal, Cardiac Failure Acute, Heart Rate Decreased, Ventricular Hypertrophy, Cyanosis, Bradycardia, Cardiac Arrest, Blood Pressure Decreased, Heart Sounds Abnormal

Adverse event resulted in: death

Drug(s) suspected as cause:
Sevoflurane
    Indication: General Anaesthesia
    Start date: 2011-04-05

Fluorescein Sodium
    Dosage: 0.5 %, unk
    Indication: Mydriasis
    Start date: 2011-04-05

Phenylephrine HCL
    Dosage: 1 drop in each eye one time
    Indication: Mydriasis
    Start date: 2011-04-05

Other drugs received by patient: Benoxinate Hydrochloride; Atarax; Xalatan; Tropicamide



Possible Sevoflurane side effects in 43 year old male

Reported by a health professional (non-physician/pharmacist) from Kazakhstan on 2012-02-15

Patient: 43 year old male, weighing 71.0 kg (156.2 pounds)

Reactions: Atrial Fibrillation, Ventricular Fibrillation, Cardiac Arrest, Hypokalaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Sevoflurane

Other drugs received by patient: Pipecuronium; Pipecuronium; Fenlanili; Sucsametoni; Sucsametoni



Possible Sevoflurane side effects in 5 month old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-02-06

Patient: 5 month old female

Reactions: Atrioventricular Block, Cardiac Arrest

Adverse event resulted in: death

Drug(s) suspected as cause:
Propranolol
    Dosage: 6 mg, 2x/day
    Administration route: Oral
    Start date: 2011-06-16
    End date: 2011-06-22

Succinylcholine Chloride
    Dosage: 30 mg, unk
    Start date: 2011-06-22
    End date: 2011-06-22

Aetoxisclerol
    Dosage: unk
    Indication: Varices Oesophageal
    Start date: 2011-06-22
    End date: 2011-06-22

Diprivan
    Dosage: 30 mg, unk
    Start date: 2011-06-22
    End date: 2011-06-22

Albumine ^lfb^
    Dosage: unk
    Start date: 2011-05-31

Aldactone
    Dosage: unk
    Start date: 2011-05-31

Sandostatin
    Dosage: unk
    Start date: 2011-06-22
    End date: 2011-06-22

Sevoflurane
    Dosage: unk
    Start date: 2011-06-22
    End date: 2011-06-22

Sufentanil Citrate
    Dosage: unk
    Start date: 2011-06-22
    End date: 2011-06-22

Propranolol
    Dosage: 3 mg, 2x/day
    Administration route: Oral
    Indication: Haemangioma of Skin
    Start date: 2011-06-09
    End date: 2011-06-16



Possible Sevoflurane side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-15

Patient: male, weighing 67.7 kg (148.9 pounds)

Reactions: Stress Cardiomyopathy, Cardiac Arrest

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Sevoflurane

Other drugs received by patient: Fentanyl; Epinephrine; Rocuronium Bromide; Remifentanil; Ropivacaine Hydrochloride; Flurbiprofen; Propofol; Phenylephrine Hydrochloride; Droperidol; Cefazolin Sodium; Epidural Anesthetics; Rocuronium Bromide; Ephedrine Hydrochloride



Possible Sevoflurane side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-13

Patient: male, weighing 67.7 kg (148.9 pounds)

Reactions: Cardiac Arrest, Stress Cardiomyopathy

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Sevoflurane

Other drugs received by patient: Epidural Anesthetics; Propofol; Droperidol; Ropivacaine Hydrochloride; Epinephrine; Remifentanil; Phenylephrine Hydrochloride; Cefazolin Sodium; Rocuronium Bromide; Fentanyl; Flurbiprofen; Ephedrine Hydrochloride



Possible Sevoflurane side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-05

Patient: male

Reactions: Cardiac Arrest, Stress Cardiomyopathy

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Sevoflurane

Other drugs received by patient: Remifentanil; Epidural Anesthetics; Epinephrine; Fentanyl



Possible Sevoflurane side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-11-21

Patient: male

Reactions: Stress Cardiomyopathy, Cardiac Arrest

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Sevoflurane

Other drugs received by patient: Fentanyl-100; Remifentanil; Epinephrine; Epidural Anesthetics



Possible Sevoflurane side effects in 43 year old male

Reported by a health professional (non-physician/pharmacist) from Kazakhstan on 2011-11-11

Patient: 43 year old male, weighing 71.0 kg (156.2 pounds)

Reactions: Atrial Fibrillation, Ventricular Fibrillation, Cardiac Arrest, Hypokalaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Sevoflurane

Other drugs received by patient: Sucsametoni; Pipecuronium; Sucsametoni; Fenlanili; Pipecuronium



Possible Sevoflurane side effects in 68 year old female

Reported by a physician from Netherlands on 2011-10-20

Patient: 68 year old female, weighing 84.0 kg (184.8 pounds)

Reactions: Torsade DE Pointes, Cardiac Arrest

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Sevoflurane
    Indication: Induction of Anaesthesia
    Start date: 2009-06-17
    End date: 2009-06-17

Fluconazole
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-06-15
    End date: 2009-06-17

Other drugs received by patient: Propofol; Piperacillin and Tazobactam; Sufentanil Citrate; Amlodipine; Nexium; Spironolactone; Acetaminophen; Sintrom

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