Index of reports
> Cases with Cardiac Arrest (20)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Sevoflurane where reactions include cardiac arrest. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Sevoflurane side effects in 18 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-07
Patient: 18 year old male
Reactions: Bloody Discharge, Puncture Site Haemorrhage, Haemorrhage, Coagulopathy, Hyperthermia Malignant, Ventricular Arrhythmia, Organ Failure, Cardiac Failure, NO Therapeutic Response, Pulmonary Oedema, Cardiac Arrest
Adverse event resulted in: death
Drug(s) suspected as cause:
Dantrolene Sodium
Dosage: 2.5 mg/kg, initial dose
Indication: Hyperthermia Malignant
Succinylcholine Chloride
Sevoflurane
Dosage: gas anesthetic
Indication: Anaesthesia
Possible Sevoflurane side effects in male
Reported by a physician from United States on 2012-07-10
Patient: male
Reactions: Haemorrhage, NO Therapeutic Response, Coagulopathy, Hyperthermia Malignant, Ventricular Arrhythmia, Pulmonary Oedema, Cardiac Arrest, Organ Failure
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Sevoflurane
Dosage: gas anesthetic
Indication: Anaesthesia
Dantrolene Sodium
Dosage: see image
Indication: Hyperthermia Malignant
Possible Sevoflurane side effects in female
Reported by a physician from France on 2012-07-03
Patient: female, weighing 70.0 kg (154.0 pounds)
Reactions: Ventricular Tachycardia, Cardiac Arrest
Adverse event resulted in: death
Drug(s) suspected as cause:
Nefopam Mylan
Dosage: 20 mg daily dose
Indication: Product Used FOR Unknown Indication
Start date: 2012-04-18
End date: 2012-04-18
Propofol
Dosage: 170 mg daily dose
Indication: Induction of Anaesthesia
Start date: 2012-04-18
End date: 2012-04-18
Ephedrine Aguettant
Dosage: 6 mg daily dose
Indication: Product Used FOR Unknown Indication
Start date: 2012-04-18
End date: 2012-04-18
Droperidol
Dosage: 1.25 mg daily dose
Indication: Product Used FOR Unknown Indication
Start date: 2012-04-18
End date: 2012-04-18
Sevoflurane
Indication: Induction of Anaesthesia
Start date: 2012-04-18
End date: 2012-04-18
Cefazolin
Dosage: 2 gram daily dose
Indication: Premedication
Start date: 2012-04-18
End date: 2012-04-18
Acetaminophen
Dosage: 1 gram daily dose
Indication: Induction of Anaesthesia
Start date: 2012-04-18
End date: 2012-04-18
Ketamine HCL
Dosage: 15 mg daily dose
Indication: Induction of Anaesthesia
Start date: 2012-04-18
End date: 2012-04-18
Midazolam
Dosage: 1.5 mg daily dose
Indication: Induction of Anaesthesia
Start date: 2012-04-18
End date: 2012-04-18
Nimbex
Indication: Induction of Anaesthesia
Start date: 2012-04-18
End date: 2012-04-18
Sufentanil Renaudin
Dosage: 50 mcg daily dose
Indication: Induction of Anaesthesia
Start date: 2012-04-18
End date: 2012-04-18
Other drugs received by patient: Carteolol Hydrochloride; Omeprazole; Ibuprofen; Acetaminophen and Tramadol HCL
Possible Sevoflurane side effects in male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-21
Patient: male, weighing 100.0 kg (220.0 pounds)
Reactions: Post Procedural Complication, Atrioventricular Block Complete, Drug Interaction, Continuous Haemodiafiltration, Nodal Rhythm, Atrial Fibrillation, Toxicity To Various Agents, Anaesthetic Complication Cardiac, Sedation, Glossoptosis, Depressed Level of Consciousness, Sinus Arrest, Cardiac Arrest, Oxygen Saturation Decreased
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Nicardipine HCL
Dosage: 4.16 ug/kg/min
Indication: Hypertension
Nicardipine HCL
Dosage: 4.16 ug/kg/min
Indication: Tachycardia
Sevoflurane
Dosage: unknown
Indication: Maintenance of Anaesthesia
Diltiazem
Dosage: 4.5 ug/kg/min
Indication: Hypertension
Midazolam
Dosage: 3 mg/hour, intravenous
Indication: Sedation
Other drugs received by patient: Vecuronium Bromide; Thiamylal Sodium; Fentanyl Citrate
Possible Sevoflurane side effects in 39 year old male
Reported by a individual with unspecified qualification from Japan on 2012-06-05
Patient: 39 year old male
Reactions: Drug Interaction, Sinus Arrest, Toxicity To Various Agents, Cardiac Arrest
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Nicardipine Hydrochloride Injection
Dosage: 4.17 ug/kg/min; intravenous drip
Indication: Hypertension
Midazolam
Dosage: 3 mg/hour intravenous drip
Indication: Sedation
Sevoflurane
Indication: Anaesthesia
Diltiazem
Dosage: 4.5 ug/kg/min; intravenous drip
Indication: Tachycardia
Other drugs received by patient: Fentanyl; Thiamylal Sodium; Vecuronium Bromide
Possible Sevoflurane side effects in male
Reported by a physician from Japan on 2012-04-18
Patient: male, weighing 100.0 kg (220.0 pounds)
Reactions: Overdose, Drug Interaction, Sinus Arrest, Toxicity To Various Agents, Cardiac Arrest
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Sevoflurane
Other drugs received by patient possibly interacting with the suspect drug: Diltiazem HCL
Dosage: 4.5 mcg/kg/min
Indication: Hypertension
Start date: 2010-05-25
End date: 2010-05-26
Midazolam HCL
Dosage: 3 mg/hr
Indication: Sedative Therapy
Start date: 2010-05-25
End date: 2010-05-26
Nicardipine HCL
Dosage: 4.17 mcg/kg/min
Indication: Hypertension
Start date: 2010-05-25
End date: 2010-05-26
Nicardipine HCL
Indication: Tachycardia
Diltiazem HCL
Indication: Tachycardia
Other drugs received by patient: Thiamylal Sodium; Fentanyl; Oxygen; Vecuronium Bromide
Possible Sevoflurane side effects in 35 year old female
Reported by a health professional (non-physician/pharmacist) on 2012-04-10
Patient: 35 year old female
Reactions: Hypotension, Anaesthetic Complication Cardiac, Long QT Syndrome, Ventricular Tachycardia, Ventricular Fibrillation, Bradycardia, Apnoea, Cardiac Arrest
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Sevoflurane
Dosage: inhalation
Indication: Anaesthesia
Epinephrine
Dosage: (1 mg), intravenous bolus, unknown (4 total), intravenous bolus
Indication: Anaesthesia
Epinephrine
Dosage: (1 mg), intravenous bolus, unknown (4 total), intravenous bolus
Indication: Ventricular Fibrillation
Xylocaine W / Epinephrine
Dosage: (y), nasal
Indication: Anaesthesia
Ondansetron Hydrochloride
Dosage: (4 mg), intravenous
Indication: Product Used FOR Unknown Indication
Amiodarone HCL
Dosage: (300 mg), unknown
Indication: Ventricular Fibrillation
Amiodarone HCL
Dosage: (300 mg), unknown
Indication: Hypotension
Cocaine (Cocaine)
Dosage: (250 mg), nasal
Indication: Anaesthesia
Cocaine (Cocaine)
Dosage: (250 mg), nasal
Indication: Nasal Septal Operation
Other drugs received by patient: Oxygen (Oxygen); Atropine; Diclofenac Sodium; Nitrous Oxide W / Oxygen; Lidocaine; Propofol; Sodium Bicarbonate IN Plastic Container; Fentanyl
Possible Sevoflurane side effects in male
Reported by a physician from Japan on 2012-04-06
Patient: male, weighing 105.0 kg (231.0 pounds)
Reactions: Overdose, Drug Interaction, Sinus Arrest, Cardiac Arrest
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Sevoflurane
Other drugs received by patient possibly interacting with the suspect drug: Midazolam HCL
Dosage: continuous
Indication: Subarachnoid Haemorrhage
Start date: 2010-05-25
End date: 2010-05-26
Diltiazem HCL
Dosage: continuous
Indication: Subarachnoid Haemorrhage
Start date: 2010-05-25
End date: 2010-05-26
Nicardipine HCL
Dosage: continuous
Indication: Subarachnoid Haemorrhage
Start date: 2010-05-25
End date: 2010-05-26
Other drugs received by patient: Thiamylal Sodium; Fentanyl Citrate; Vecuronium Bromide
Possible Sevoflurane side effects in male
Reported by a physician from Japan on 2012-04-06
Patient: male, weighing 105.0 kg (231.0 pounds)
Reactions: Overdose, Drug Interaction, Sinus Arrest, Cardiac Arrest
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Sevoflurane
Other drugs received by patient possibly interacting with the suspect drug: Midazolam HCL
Dosage: continuous
Indication: Subarachnoid Haemorrhage
Start date: 2010-05-25
End date: 2010-05-26
Diltiazem HCL
Dosage: continuous
Indication: Subarachnoid Haemorrhage
Start date: 2010-05-25
End date: 2010-05-26
Nicardipine HCL
Dosage: continuous
Indication: Subarachnoid Haemorrhage
Start date: 2010-05-25
End date: 2010-05-26
Other drugs received by patient: Vecuronium Bromide; Fentanyl; Thiamylal Sodium
Possible Sevoflurane side effects in 35 year old female
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-04-03
Patient: 35 year old female
Reactions: Ventricular Tachycardia, Hypotension, Bradycardia, Ventricular Fibrillation, Cardiac Arrest, Apnoea, Long QT Syndrome
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Amiodarone HCL
Dosage: 300 mg, single
Indication: Ventricular Fibrillation
Cocaine
Indication: Nasal Septal Operation
Cocaine
Dosage: 250 mg, single
Indication: Anaesthesia
Amiodarone HCL
Indication: Hypotension
Sevoflurane
Dosage: 3%
Indication: Anaesthesia
Epinephrine
Dosage: 1mg intravenous bolus x 4
Indication: Ventricular Fibrillation
Epinephrine
Indication: Anaesthesia
Ondansetron
Dosage: 4 mg, single
Lidocaine and Epinephrine
Dosage: [lidocaine 100mg]/[epinephrine 60mcg]
Indication: Anaesthesia
Other drugs received by patient: Lidocaine; Nitrous Oxide; Propofol; Sodium Bicarbonate; Atropine; Diclofenac; Oxygen; Fentanyl
Possible Sevoflurane side effects in female
Reported by a physician from France on 2012-03-05
Patient: female, weighing 13.0 kg (28.6 pounds)
Reactions: Acute Pulmonary Oedema, Williams Syndrome, Supravalvular Aortic Stenosis, Hypercapnia, Cardiac Failure Acute, Pulmonary Haemorrhage, Ventricular Hypertrophy, Heart Rate Decreased, Electrocardiogram QRS Complex Prolonged, Cyanosis, Pulse Absent, Oxygen Saturation Immeasurable, Bradycardia, Heart Disease Congenital, Blood Pressure Immeasurable, Cardiac Arrest
Adverse event resulted in: death
Drug(s) suspected as cause:
Sevoflurane
Indication: Anaesthesia
Start date: 2011-04-05
End date: 2011-04-05
Fluorescein Sodium
Indication: Product Used FOR Unknown Indication
Start date: 2011-04-05
End date: 2011-04-05
Phenylephrine HCL
Dosage: collyre 10% one drop in each eye
Indication: Mydriasis
Start date: 2011-04-05
End date: 2011-04-05
Other drugs received by patient: Tropicamide; Benoxinate Hydrochloride; B66 500ml; Atarax
Possible Sevoflurane side effects in female
Reported by a health professional (non-physician/pharmacist) from France on 2012-03-05
Patient: female, weighing 13.0 kg (28.6 pounds)
Reactions: Acute Pulmonary Oedema, Aortic Stenosis, Conduction Disorder, Carotid Pulse Abnormal, Cardiac Failure Acute, Heart Rate Decreased, Ventricular Hypertrophy, Cyanosis, Bradycardia, Cardiac Arrest, Blood Pressure Decreased, Heart Sounds Abnormal
Adverse event resulted in: death
Drug(s) suspected as cause:
Sevoflurane
Indication: General Anaesthesia
Start date: 2011-04-05
Fluorescein Sodium
Dosage: 0.5 %, unk
Indication: Mydriasis
Start date: 2011-04-05
Phenylephrine HCL
Dosage: 1 drop in each eye one time
Indication: Mydriasis
Start date: 2011-04-05
Other drugs received by patient: Benoxinate Hydrochloride; Atarax; Xalatan; Tropicamide
Possible Sevoflurane side effects in 43 year old male
Reported by a health professional (non-physician/pharmacist) from Kazakhstan on 2012-02-15
Patient: 43 year old male, weighing 71.0 kg (156.2 pounds)
Reactions: Atrial Fibrillation, Ventricular Fibrillation, Cardiac Arrest, Hypokalaemia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Sevoflurane
Other drugs received by patient: Pipecuronium; Pipecuronium; Fenlanili; Sucsametoni; Sucsametoni
Possible Sevoflurane side effects in 5 month old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-02-06
Patient: 5 month old female
Reactions: Atrioventricular Block, Cardiac Arrest
Adverse event resulted in: death
Drug(s) suspected as cause:
Propranolol
Dosage: 6 mg, 2x/day
Administration route: Oral
Start date: 2011-06-16
End date: 2011-06-22
Succinylcholine Chloride
Dosage: 30 mg, unk
Start date: 2011-06-22
End date: 2011-06-22
Aetoxisclerol
Dosage: unk
Indication: Varices Oesophageal
Start date: 2011-06-22
End date: 2011-06-22
Diprivan
Dosage: 30 mg, unk
Start date: 2011-06-22
End date: 2011-06-22
Albumine ^lfb^
Dosage: unk
Start date: 2011-05-31
Aldactone
Dosage: unk
Start date: 2011-05-31
Sandostatin
Dosage: unk
Start date: 2011-06-22
End date: 2011-06-22
Sevoflurane
Dosage: unk
Start date: 2011-06-22
End date: 2011-06-22
Sufentanil Citrate
Dosage: unk
Start date: 2011-06-22
End date: 2011-06-22
Propranolol
Dosage: 3 mg, 2x/day
Administration route: Oral
Indication: Haemangioma of Skin
Start date: 2011-06-09
End date: 2011-06-16
Possible Sevoflurane side effects in male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-15
Patient: male, weighing 67.7 kg (148.9 pounds)
Reactions: Stress Cardiomyopathy, Cardiac Arrest
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Sevoflurane
Other drugs received by patient: Fentanyl; Epinephrine; Rocuronium Bromide; Remifentanil; Ropivacaine Hydrochloride; Flurbiprofen; Propofol; Phenylephrine Hydrochloride; Droperidol; Cefazolin Sodium; Epidural Anesthetics; Rocuronium Bromide; Ephedrine Hydrochloride
Possible Sevoflurane side effects in male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-13
Patient: male, weighing 67.7 kg (148.9 pounds)
Reactions: Cardiac Arrest, Stress Cardiomyopathy
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Sevoflurane
Other drugs received by patient: Epidural Anesthetics; Propofol; Droperidol; Ropivacaine Hydrochloride; Epinephrine; Remifentanil; Phenylephrine Hydrochloride; Cefazolin Sodium; Rocuronium Bromide; Fentanyl; Flurbiprofen; Ephedrine Hydrochloride
Possible Sevoflurane side effects in male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-05
Patient: male
Reactions: Cardiac Arrest, Stress Cardiomyopathy
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Sevoflurane
Other drugs received by patient: Remifentanil; Epidural Anesthetics; Epinephrine; Fentanyl
Possible Sevoflurane side effects in male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-11-21
Patient: male
Reactions: Stress Cardiomyopathy, Cardiac Arrest
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Sevoflurane
Other drugs received by patient: Fentanyl-100; Remifentanil; Epinephrine; Epidural Anesthetics
Possible Sevoflurane side effects in 43 year old male
Reported by a health professional (non-physician/pharmacist) from Kazakhstan on 2011-11-11
Patient: 43 year old male, weighing 71.0 kg (156.2 pounds)
Reactions: Atrial Fibrillation, Ventricular Fibrillation, Cardiac Arrest, Hypokalaemia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Sevoflurane
Other drugs received by patient: Sucsametoni; Pipecuronium; Sucsametoni; Fenlanili; Pipecuronium
Possible Sevoflurane side effects in 68 year old female
Reported by a physician from Netherlands on 2011-10-20
Patient: 68 year old female, weighing 84.0 kg (184.8 pounds)
Reactions: Torsade DE Pointes, Cardiac Arrest
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Sevoflurane
Indication: Induction of Anaesthesia
Start date: 2009-06-17
End date: 2009-06-17
Fluconazole
Indication: Product Used FOR Unknown Indication
Start date: 2009-06-15
End date: 2009-06-17
Other drugs received by patient: Propofol; Piperacillin and Tazobactam; Sufentanil Citrate; Amlodipine; Nexium; Spironolactone; Acetaminophen; Sintrom
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