This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Septocaine and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (31)
Life Threatening Events (1)
Disability (5)
Reports by Reaction Type
Dyspnoea (15),
Atelectasis (12),
Dental Plaque (12),
Device Related Infection (12),
Multiple Myeloma (12),
Pyrexia (12),
Tooth Discolouration (12),
Sedation (12),
Hypoxia (12),
Intervertebral Disc Degeneration (12),
Pleural Effusion (12),
Vertebral Foraminal Stenosis (12)
Below are a few examples of reports where side effects / adverse reactions may be related to Septocaine. For a complete list or a specific selection of reports, please use the links above.
Possible Septocaine side effects in 62 year old male
Reported by a consumer/non-health professional from United States on 2012-08-06
Patient: 62 year old male, weighing 79.4 kg (174.6 pounds)
Reactions: Nerve Injury, Ageusia, Tongue Disorder, Pain, Discomfort
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Septocaine
Dosage: 1 carpule single dental
Indication: Nerve Block
Start date: 2012-06-27
End date: 2012-06-27
Septocaine
Dosage: 1 carpule single dental
Indication: Local Anaesthesia
Start date: 2012-06-27
End date: 2012-06-27
Possible Septocaine side effects in male
Reported by a consumer/non-health professional from United States on 2012-07-24
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Dental Plaque, Arteriovenous Fistula Occlusion, Endocarditis, Vascular Pseudoaneurysm, Staphylococcal Bacteraemia, Vertebral Foraminal Stenosis, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Pancreatic Atrophy, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Arteriosclerosis Coronary Artery, Hepatitis C, Osteoporosis, Chills, Mental Status Changes, Multiple Myeloma, Wound Decomposition, Kyphosis, Tooth Discolouration, Oedema, Bone Disorder, Splenomegaly, Device Related Sepsis, Fluid Overload, Cataract, Gouty Arthritis, Dyspnoea, Febrile Neutropenia, Ear Infection, Hypophosphataemia, Gingival Pain, Conjunctival Haemorrhage, Sepsis, Hyperthyroidism, Asthenia, Lung Infiltration, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Pyrexia, Device Related Infection, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Enterocolitis, Progressive Supranuclear Palsy, Cardiac Failure Congestive, Hiatus Hernia, Pneumonia, Cellulitis, Anaemia, Encephalopathy, Respiratory Distress, Convulsion, Peritonitis, Cholelithiasis, Prostatomegaly, Impaired Gastric Emptying, Aortic Valve Incompetence, Nephropathy, Atelectasis, Synovial Rupture, Neuropathy Peripheral, Ileus, Pulmonary Congestion, Intervertebral Disc Degeneration, Dizziness, Pleural Effusion, Toothache, Cholecystitis, Arteriovenous Fistula Thrombosis, Gastrooesophageal Reflux Disease, Thrombocytopenia, Azotaemia, Jugular Vein Thrombosis, Blood Pressure Increased, Mitral Valve Disease, Bone Lesion, Urinary Tract Infection, Hyponatraemia, Osteolysis, Renal Failure Chronic, Rash Macular, Osteoarthritis, Mucosal Inflammation, Osteonecrosis of JAW, Lacunar Infarction, Sexual Dysfunction, Spinal Osteoarthritis, Bronchitis, Sinus Tachycardia, Hypertension, Superior Vena Cava Syndrome, Deep Vein Thrombosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Dexamethasone; MS Contin; Zofran; Protonix; Valium; Compazine; Folic Acid; Coumadin; Dilaudid; Promethazine Hydrochloride; Adriamycin PFS; Dilantin; Ferrous Sulfate TAB; Loperamide; Zyvox; Velcade; Nitroglycerin; Ativan; Trimox; Daily-Vite; Acetaminophen; Tamoxifen Citrate; Morphine Sulfate; Remeron; Oxycontin; Colace; Plavix; Omeprazole; Xanax; Methadone HCL; Prednisone; Senokot; Lopressor; Citanest; Phenytoin; Vincristine; Thalidomide; Amitriptyline Hydrochloride; Megace; Tylenol; Aspirin; Heparin; Indomethacin; Bisacodyl; Epogen; Toprol-XL; Vasotec; Reglan; Melphalan Hydrochloride; Paxil; Lidocaine Hydrochloride; Lorazepam
Possible Septocaine side effects in male
Reported by a lawyer from United States on 2012-07-23
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Dental Plaque, Arteriovenous Fistula Occlusion, Oedema Peripheral, Endocarditis, Vascular Pseudoaneurysm, Staphylococcal Bacteraemia, Vertebral Foraminal Stenosis, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Pancreatic Atrophy, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Arteriosclerosis Coronary Artery, Hepatitis C, Osteoporosis, Chills, Mental Status Changes, Multiple Myeloma, Wound Decomposition, Kyphosis, Tooth Discolouration, Oedema, Bone Disorder, Splenomegaly, Fluid Overload, Device Related Sepsis, Cataract, Gouty Arthritis, Dyspnoea, Ear Infection, Febrile Neutropenia, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Hyperthyroidism, Lung Infiltration, Asthenia, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Device Related Infection, Pyrexia, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Enterocolitis, Progressive Supranuclear Palsy, Cardiac Failure Congestive, Hiatus Hernia, Pneumonia, Cellulitis, Anaemia, Encephalopathy, Respiratory Distress, Peritonitis, Convulsion, Cholelithiasis, Joint Swelling, Prostatomegaly, Impaired Gastric Emptying, Aortic Valve Incompetence, Nephropathy, Synovial Rupture, Atelectasis, Neuropathy Peripheral, Ileus, Pulmonary Congestion, Intervertebral Disc Degeneration, Dizziness, Pleural Effusion, Cholecystitis, Toothache, Arteriovenous Fistula Thrombosis, Thrombocytopenia, Gastrooesophageal Reflux Disease, Jugular Vein Thrombosis, Azotaemia, Blood Pressure Increased, Mitral Valve Disease, Bone Lesion, Urinary Tract Infection, Hyponatraemia, Osteolysis, Renal Failure Chronic, Rash Macular, Osteoarthritis, Mucosal Inflammation, Osteonecrosis of JAW, Sexual Dysfunction, Spinal Osteoarthritis, Bronchitis, Hypertension, Sinus Tachycardia, Superior Vena Cava Syndrome, Deep Vein Thrombosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Adriamycin PFS; Oxycontin; Nitroglycerin; Colace; Lopressor; Plavix; Citanest; Lorazepam; Loperamide; Lidocaine Hydrochloride; Trimox; Dilaudid; Promethazine Hydrochloride; Velcade; Remeron; Compazine; Protonix; Folic Acid; Coumadin; Aspirin; Tamoxifen Citrate; Epogen; Megace; Prednisone; Senokot; Daily-Vite; Dilantin; Valium; Bisacodyl; Zyvox; Tylenol; Ativan; Heparin; Zofran; Melphalan Hydrochloride; Xanax; Ferrous Sulfate TAB; Vincristine; MS Contin; Morphine Sulfate; Amitriptyline HCL; Methadone HCL; Toprol-XL; Omeprazole; Dexamethasone; Thalidomide; Vasotec; Reglan; Paxil; Indomethacin; Phenytoin; Acetaminophen
Possible Septocaine side effects in female
Reported by a lawyer from United States on 2012-07-06
Patient: female
Reactions: Nerve Injury, Sensory Loss
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Citanest
Start date: 2012-06-10
End date: 2012-06-10
Septocaine
Indication: Local Anaesthesia
Start date: 2012-06-10
End date: 2012-06-10
Possible Septocaine side effects in female
Reported by a health professional (non-physician/pharmacist) from France on 2012-05-30
Patient: female
Reactions: Dysphagia, Dyspnoea, Exophthalmos, Fear, Vocal Cord Paralysis, Dysgeusia, Anxiety, Heart Rate Decreased, Fatigue, Neck Pain, Bronchospasm, Blood Pressure Decreased, Accidental Exposure
Drug(s) suspected as cause:
Septocaine
Other drugs received by patient: Crestor
Possible Septocaine side effects in 67 year old female
Reported by a consumer/non-health professional from Denmark on 2012-05-24
Patient: 67 year old female
Reactions: Glossodynia, Oral Pain
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Septocaine
Possible Septocaine side effects in 42 year old male
Reported by a physician from United States on 2012-05-17
Patient: 42 year old male, weighing 83.9 kg (184.6 pounds)
Reactions: Dyspnoea, Pharyngeal Hypoaesthesia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Lido
Septocaine
Dosage: septocaine po
Administration route: Oral
Indication: Hypoaesthesia
Start date: 2012-05-10
End date: 2012-05-10
TAC 20% Topical Anesthetic Lido20% Tetracaine4% Professional Arts Phar
Dosage: topical
Administration route: Topical
Indication: Hypoaesthesia
Start date: 2012-05-10
End date: 2012-05-10
Tetracaine Polygyl Sterile Ophthalmic Solution
Possible Septocaine side effects in male
Reported by a lawyer from United States on 2012-05-10
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Oedema Peripheral, Vascular Pseudoaneurysm, Endocarditis, Vertebral Foraminal Stenosis, Staphylococcal Bacteraemia, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Hepatitis C, Osteoporosis, Chills, Mental Status Changes, Wound Decomposition, Multiple Myeloma, Kyphosis, Chest Pain, Tooth Discolouration, Oedema, Bone Disorder, Splenomegaly, Fluid Overload, Device Related Sepsis, Gouty Arthritis, Dyspnoea, Viral Infection, Cataract, Ear Infection, Febrile Neutropenia, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Lung Infiltration, Hyperthyroidism, Asthenia, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Device Related Infection, Pyrexia, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Cardiac Failure Congestive, Progressive Supranuclear Palsy, Cellulitis, Hiatus Hernia, Pneumonia, Anaemia, Encephalopathy, Respiratory Distress, Peritonitis, Convulsion, Cholelithiasis, Joint Swelling, Prostatomegaly, Impaired Gastric Emptying, Aortic Valve Incompetence, Nephropathy, Atelectasis, Synovial Rupture, Neuropathy Peripheral, Ileus, Pulmonary Congestion, Intervertebral Disc Degeneration, Pleural Effusion, Dizziness, Arteriovenous Fistula Thrombosis, Toothache, Cholecystitis, Azotaemia, Gastrooesophageal Reflux Disease, Thrombocytopenia, Jugular Vein Thrombosis, Blood Pressure Increased, Mitral Valve Disease, Bone Lesion, Urinary Tract Infection, Hyponatraemia, Osteolysis, Renal Failure Chronic, Rash Macular, Osteoarthritis, Mucosal Inflammation, Osteonecrosis of JAW, Sexual Dysfunction, Bronchitis, Spinal Osteoarthritis, Sinus Tachycardia, Superior Vena Cava Syndrome, Hypertension, Deep Vein Thrombosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Protonix; Folic Acid; Reglan; Lidocaine Hydrochloride; Lorazepam; Acetaminophen; Vincristine; Megace; Lopressor; Aspirin; Indomethacin; Dilantin; Ferrous Sulfate TAB; Promethazine HCL; Adriamycin PFS; Morphine; Remeron; Compazine; Prednisone TAB; Toprol-XL; Melphalan Hydrochloride; Daily-Vite; Dexamethasone; Methadone HCL; Coumadin; Plavix; Trimox; Omeprazole; Ativan; Thalidomide; Epogen; Vasotec; Tylenol (Caplet); Colace; Paxil; Phenytoin; Loperamide; Tamoxifen Citrate; Zyvox; Velcade; Citanest; Heparin; Xanax; Valium; Dilaudid; MS Contin; Amitriptyline HCL; Zofran; Oxycontin; Nitroglycerin; Senokot; Bisacodyl
Possible Septocaine side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-08
Patient: female
Reactions: Contusion, Oedema Mouth
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Septocaine
Possible Septocaine side effects in 67 year old female
Reported by a consumer/non-health professional from Denmark on 2012-05-04
Patient: 67 year old female
Reactions: Glossodynia, Oral Pain
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Septocaine
Possible Septocaine side effects in 42 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-03
Patient: 42 year old female, weighing 70.3 kg (154.7 pounds)
Reactions: Dysgeusia, Ageusia, Anosmia
Drug(s) suspected as cause:
Septocaine
Other drugs received by patient: Carbocaine
Possible Septocaine side effects in 81 year old female
Reported by a individual with unspecified qualification from France on 2012-03-09
Patient: 81 year old female
Reactions: Dysgeusia, Dyspnoea, Exophthalmos, Dysphagia, Bronchospasm, Vocal Cord Paralysis, Hypoaesthesia
Drug(s) suspected as cause:
Septocaine
Other drugs received by patient: Crestor
Possible Septocaine side effects in male
Reported by a consumer/non-health professional from United States on 2012-03-06
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Abdominal Pain, Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Oedema Peripheral, Endocarditis, Vascular Pseudoaneurysm, Staphylococcal Bacteraemia, Vertebral Foraminal Stenosis, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Hepatitis C, Osteoporosis, Chills, Mental Status Changes, Multiple Myeloma, Wound Decomposition, Kyphosis, Tooth Discolouration, Chest Pain, Oedema, Bone Disorder, Splenomegaly, Fluid Overload, Device Related Sepsis, Viral Infection, Gouty Arthritis, Cataract, Dyspnoea, Ear Infection, Febrile Neutropenia, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Lung Infiltration, Asthenia, Hyperthyroidism, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Device Related Infection, Pyrexia, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Cardiac Failure Congestive, Progressive Supranuclear Palsy, Cellulitis, Pneumonia, Anaemia, Encephalopathy, Respiratory Distress, Convulsion, Cholelithiasis, Joint Swelling, Impaired Gastric Emptying, Aortic Valve Incompetence, Nephropathy, Atelectasis, Synovial Rupture, Neuropathy Peripheral, Ileus, Pulmonary Congestion, Pleural Effusion, Intervertebral Disc Degeneration, Dizziness, Arteriovenous Fistula Thrombosis, Toothache, Cholecystitis, Jugular Vein Thrombosis, Gastrooesophageal Reflux Disease, Azotaemia, Thrombocytopenia, Blood Pressure Increased, Mitral Valve Disease, Bone Lesion, Urinary Tract Infection, Hyponatraemia, Osteolysis, Renal Failure Chronic, Rash Macular, Mucosal Inflammation, Osteoarthritis, Osteonecrosis of JAW, Sexual Dysfunction, Bronchitis, Spinal Osteoarthritis, Sinus Tachycardia, Superior Vena Cava Syndrome, Hypertension, Deep Vein Thrombosis, Infectious Peritonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Vincristine; Adriamycin PFS; Folic Acid; Reglan; Coumadin; Lidocaine HCL; Daily-Vite; Omeprazole; Indomethacin; Epogen; Toprol-XL; Melphalan Hydrochloride; Paxil; Phenytoin; Dilaudid; Zyvox; Remeron; Ativan; Plavix; Citanest; Ferrous Sulfate TAB; Thalidomide; Velcade; Megace; Vasotec; Protonix; Heparin; Dexamethasone; Methadon HCL TAB; Acetaminophen; Hematopoetic Progenitor Cells Human; Xanax; Loperamide HCL; Amitriptyline HCL; Compazine; Prednisone TAB; Oxycontin; Aspirin; Trimox; Bisacodyl; Morphine; Senokot; Colace; Lopressor; Dilantin; Lorazepam; Acetaminophen; Tamoxifen Citrate; Promethazine Hydrochloride; MS Contin; Zofran; Nitroglycerin; Valium
Possible Septocaine side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-01
Patient: male, weighing 84.1 kg (185.0 pounds)
Reactions: Circumstance or Information Capable of Leading To Medication Error, Wrong Drug Administered, Product Label Confusion
Drug(s) suspected as cause:
Carbocain
Dosage: 1.7 ml one time oral anesthesia via inferior alveolar
Indication: Anaesthesia
Start date: 2012-02-28
Septocaine
Dosage: 1.7 ml one time oral anesthesia via inferior alveolar
Indication: Anaesthesia
Start date: 2012-02-28
Possible Septocaine side effects in 31 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-02-22
Patient: 31 year old male, weighing 80.0 kg (176.0 pounds)
Reactions: Injection Site Inflammation, Presyncope, Loss of Consciousness
Drug(s) suspected as cause:
Septocaine
Possible Septocaine side effects in 22 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-02-22
Patient: 22 year old male, weighing 60.0 kg (132.0 pounds)
Reactions: Eye Movement Disorder, Erythema, Pallor, Muscle Tightness, Loss of Consciousness
Drug(s) suspected as cause:
Septocaine
Dosage: 3/4 cartridge dental
Indication: Local Anaesthesia
Start date: 2011-12-28
X Ogel Enfant, Gel Gingival
Dosage: dental
Indication: Local Anaesthesia
Start date: 2011-12-28
Other drugs received by patient: Ixprim (Tramadol, Paracetamol)
Possible Septocaine side effects in male
Reported by a lawyer from United States on 2012-02-01
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Abdominal Pain, Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Oedema Peripheral, Vascular Pseudoaneurysm, Endocarditis, Vertebral Foraminal Stenosis, Staphylococcal Bacteraemia, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Osteoporosis, Hepatitis C, Chills, Mental Status Changes, Wound Decomposition, Multiple Myeloma, Kyphosis, Chest Pain, Tooth Discolouration, Oedema, Bone Disorder, Decreased Appetite, Fluid Overload, Device Related Sepsis, Gouty Arthritis, Dyspnoea, Viral Infection, Vomiting, Cataract, Ear Infection, Febrile Neutropenia, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Asthenia, Hyperthyroidism, Lung Infiltration, Weight Decreased, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Device Related Infection, Pyrexia, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Cardiac Failure Congestive, Progressive Supranuclear Palsy, Cellulitis, Pneumonia, Anaemia, Respiratory Distress, Convulsion, Cholelithiasis, Joint Swelling, Impaired Gastric Emptying, Nephropathy, Atelectasis, Synovial Rupture, Constipation, Fatigue, Neuropathy Peripheral, Ileus, Pulmonary Congestion, Dizziness, Pleural Effusion, Intervertebral Disc Degeneration, Cholecystitis, Toothache, Arteriovenous Fistula Thrombosis, Azotaemia, Gastrooesophageal Reflux Disease, Thrombocytopenia, Jugular Vein Thrombosis, Blood Pressure Increased, Mitral Valve Disease, Nausea, Bone Lesion, Urinary Tract Infection, Osteolysis, Renal Failure Chronic, Rash Macular, Osteoarthritis, Mucosal Inflammation, Osteonecrosis of JAW, Diarrhoea, Sexual Dysfunction, Spinal Osteoarthritis, Hypertension, Superior Vena Cava Syndrome, Deep Vein Thrombosis, Infectious Peritonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Compazine; Prednisone TAB; Oxycontin; Acetaminophen; Reglan; Toprol-XL; Citanest; Lidocaine HCL; Heparin; Indomethacin; Lorazepam; Acetaminophen; MS Contin; Morphine; Amitriptyline HCL; Dexamethasone; Epogen; Vincristine; Adriamycin PFS; Methadone HCL; Nitroglycerin; Melphalan Hydrochloride; Aspirin; Daily-Vite; Omeprazole; Xanax; Phenytoin; Thalidomide; Vasotec; Folic Acid; Senokot; Ativan; Hematopoetic Progenitor Cells Human; Coumadin; Trimox; Ferrous Sulfate TAB; Megace; Ondansetron HCL; Colace; Lopressor; Paxil; Velcade; Remeron; Protonix; Plavix; Dilantin
Possible Septocaine side effects in male
Reported by a physician from United States on 2012-01-02
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Abdominal Pain, Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Oedema Peripheral, Vascular Pseudoaneurysm, Endocarditis, Vertebral Foraminal Stenosis, Staphylococcal Bacteraemia, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Hepatitis C, Osteoporosis, Chills, Mental Status Changes, Multiple Myeloma, Wound Decomposition, Kyphosis, Tooth Discolouration, Chest Pain, Oedema, Bone Disorder, Decreased Appetite, Fluid Overload, Device Related Sepsis, Viral Infection, Cataract, Dyspnoea, Vomiting, Gouty Arthritis, Ear Infection, Febrile Neutropenia, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Asthenia, Lung Infiltration, Hyperthyroidism, Weight Decreased, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Pyrexia, Device Related Infection, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Cardiac Failure Congestive, Progressive Supranuclear Palsy, Pneumonia, Cellulitis, Anaemia, Respiratory Distress, Convulsion, Cholelithiasis, Joint Swelling, Impaired Gastric Emptying, Nephropathy, Synovial Rupture, Atelectasis, Constipation, Neuropathy Peripheral, Fatigue, Ileus, Pulmonary Congestion, Intervertebral Disc Degeneration, Pleural Effusion, Dizziness, Arteriovenous Fistula Thrombosis, Cholecystitis, Toothache, Gastrooesophageal Reflux Disease, Thrombocytopenia, Azotaemia, Jugular Vein Thrombosis, Blood Pressure Increased, Mitral Valve Disease, Nausea, Bone Lesion, Urinary Tract Infection, Osteolysis, Renal Failure Chronic, Rash Macular, Mucosal Inflammation, Osteoarthritis, Diarrhoea, Osteonecrosis of JAW, Sexual Dysfunction, Spinal Osteoarthritis, Hypertension, Superior Vena Cava Syndrome, Deep Vein Thrombosis, Infectious Peritonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Amitriptyline HCL; Toprol-XL; Hematopoetic Progenitor Cells Human; Melphalan Hydrochloride; Plavix; Lidocaine HCL; Dexamethasone; Heparin; Indomethacin; Lorazepam; Phenytoin; MS Contin; Senokot; Reglan; Trimox; Dilantin; Vincristine; Megace; Vasotec; Coumadin; Lopressor; Paxil; Citanest; Daily-Vite; Adriamycin PFS; Remeron; Compazine; Ativan; Ferrous Sulfate TAB; Thalidomide; Colace; Omeprazole; Velcade; Methadone HCL; Epogen; Zofran; Oxycontin; Nitroglycerin; Protonix; Acetaminophen; Aspirin; Xanax; Morphine; Prednisone; Folic Acid; Acetaminophen
Possible Septocaine side effects in 30 year old female
Reported by a consumer/non-health professional from United States on 2011-12-27
Patient: 30 year old female, weighing 81.6 kg (179.6 pounds)
Reactions: Nerve Injury, Glossodynia, Hypoaesthesia Oral
Drug(s) suspected as cause:
Septocaine
Possible Septocaine side effects in male
Reported by a health professional (non-physician/pharmacist) from Denmark on 2011-12-14
Patient: male
Reactions: Sensory Disturbance, Facial Pain, Paraesthesia
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Septocaine
Possible Septocaine side effects in 46 year old female
Reported by a consumer/non-health professional from United States on 2011-12-07
Patient: 46 year old female, weighing 46.3 kg (101.8 pounds)
Reactions: Paralysis, Hypoaesthesia, Tongue Paralysis, Muscle Tightness, Loss of Consciousness, Paraesthesia, Viith Nerve Paralysis, Speech Disorder, Burning Sensation, Throat Irritation, Joint Swelling, Sinus Disorder, Vision Blurred, Memory Impairment, Feeling Abnormal, Blister
Drug(s) suspected as cause:
Septocaine
Indication: Artificial Crown Procedure
Start date: 2009-12-22
End date: 2010-06-07
Septocaine
Indication: Tooth Extraction
Start date: 2009-12-22
End date: 2010-06-07
Possible Septocaine side effects in male
Reported by a physician from United States on 2011-12-06
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Abdominal Pain, Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Oedema Peripheral, Endocarditis, Vascular Pseudoaneurysm, Staphylococcal Bacteraemia, Vertebral Foraminal Stenosis, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Hepatitis C, Osteoporosis, Chills, Mental Status Changes, Wound Decomposition, Multiple Myeloma, Kyphosis, Tooth Discolouration, Chest Pain, Oedema, Bone Disorder, Decreased Appetite, Device Related Sepsis, Fluid Overload, Viral Infection, Dyspnoea, Gouty Arthritis, Vomiting, Cataract, Ear Infection, Febrile Neutropenia, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Asthenia, Hyperthyroidism, Lung Infiltration, Weight Decreased, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Pyrexia, Device Related Infection, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Progressive Supranuclear Palsy, Cardiac Failure Congestive, Cellulitis, Pneumonia, Anaemia, Respiratory Distress, Convulsion, Cholelithiasis, Joint Swelling, Impaired Gastric Emptying, Nephropathy, Synovial Rupture, Atelectasis, Constipation, Fatigue, Neuropathy Peripheral, Ileus, Pulmonary Congestion, Intervertebral Disc Degeneration, Pleural Effusion, Dizziness, Toothache, Arteriovenous Fistula Thrombosis, Cholecystitis, Azotaemia, Thrombocytopenia, Gastrooesophageal Reflux Disease, Jugular Vein Thrombosis, Blood Pressure Increased, Mitral Valve Disease, Nausea, Bone Lesion, Urinary Tract Infection, Osteolysis, Renal Failure Chronic, Rash Macular, Osteoarthritis, Mucosal Inflammation, Osteonecrosis of JAW, Diarrhoea, Sexual Dysfunction, Spinal Osteoarthritis, Hypertension, Superior Vena Cava Syndrome, Deep Vein Thrombosis, Infectious Peritonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Thalidomide; Folic Acid; Colace; Melphalan Hydrochloride; Aspirin; Methadone; Zofran; Prednisone TAB; Protonix; Hematopoetic Progenitor Cells Human; Citanest; Daily-Vite; Amitriptyline HCL; Nitroglycerin; Dexamethasone; Oxycontin; Senokot; Ativan; Plavix; Adriamycin PFS; Remeron; Megace; Vasotec; Reglan; Trimox; Omeprazole; Vincristine; Morphine; Epogen; Compazine; Acetaminophen; Coumadin; Velcade; MS Contin; Toprol-XL; Lopressor; Paxil; Lidocaine HCL
Possible Septocaine side effects in 52 year old female
Reported by a health professional (non-physician/pharmacist) from Denmark on 2011-11-29
Patient: 52 year old female, weighing 52.0 kg (114.4 pounds)
Reactions: Nerve Injury
Drug(s) suspected as cause:
Septocaine
Possible Septocaine side effects in male
Reported by a lawyer from United States on 2011-11-17
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Abdominal Pain, Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Oedema Peripheral, Vascular Pseudoaneurysm, Endocarditis, Vertebral Foraminal Stenosis, Staphylococcal Bacteraemia, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Hepatitis C, Osteoporosis, Chills, Mental Status Changes, Multiple Myeloma, Wound Decomposition, Kyphosis, Tooth Discolouration, Chest Pain, Oedema, Bone Disorder, Decreased Appetite, Fluid Overload, Device Related Sepsis, Gouty Arthritis, Vomiting, Viral Infection, Cataract, Dyspnoea, Febrile Neutropenia, Ear Infection, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Asthenia, Lung Infiltration, Hyperthyroidism, Weight Decreased, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Pyrexia, Device Related Infection, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Progressive Supranuclear Palsy, Cardiac Failure Congestive, Pneumonia, Cellulitis, Anaemia, Respiratory Distress, Convulsion, Cholelithiasis, Joint Swelling, Impaired Gastric Emptying, Nephropathy, Atelectasis, Synovial Rupture, Constipation, Neuropathy Peripheral, Fatigue, Ileus, Pulmonary Congestion, Dizziness, Intervertebral Disc Degeneration, Pleural Effusion, Toothache, Cholecystitis, Arteriovenous Fistula Thrombosis, Thrombocytopenia, Jugular Vein Thrombosis, Azotaemia, Gastrooesophageal Reflux Disease, Blood Pressure Increased, Mitral Valve Disease, Nausea, Bone Lesion, Urinary Tract Infection, Osteolysis, Renal Failure Chronic, Rash Macular, Mucosal Inflammation, Osteoarthritis, Diarrhoea, Osteonecrosis of JAW, Sexual Dysfunction, Spinal Osteoarthritis, Hypertension, Superior Vena Cava Syndrome, Deep Vein Thrombosis, Infectious Peritonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Velcade; Prednisone TAB; Vasotec; Folic Acid; Trimox; Daily-Vite; Epogen; Ativan; Coumadin; Plavix; Aspirin; Citanest; Omeprazole; Dexamethasone; MS Contin; Megace; Protonix; Methadone HCL; Compazine; Thalidomide; Remeron; Zofran; Acetaminophen; Senokot; Melphalan Hydrochloride; Vincristine; Morphine; Toprol-XL; Colace; Reglan; Hematopoetic Progenitor Cells Human; Lopressor; Paxil; Adriamycin PFS; Amitriptyline HCL; Oxycontin; Nitroglycerin; Lidocaine HCL
Possible Septocaine side effects in male
Reported by a lawyer from United States on 2011-11-16
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Abdominal Pain, Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Oedema Peripheral, Endocarditis, Vascular Pseudoaneurysm, Staphylococcal Bacteraemia, Vertebral Foraminal Stenosis, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Osteoporosis, Hepatitis C, Chills, Mental Status Changes, Wound Decomposition, Multiple Myeloma, Kyphosis, Tooth Discolouration, Chest Pain, Oedema, Bone Disorder, Decreased Appetite, Fluid Overload, Device Related Sepsis, Cataract, Viral Infection, Gouty Arthritis, Dyspnoea, Vomiting, Febrile Neutropenia, Ear Infection, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Lung Infiltration, Asthenia, Hyperthyroidism, Weight Decreased, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Device Related Infection, Pyrexia, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Cardiac Failure Congestive, Progressive Supranuclear Palsy, Pneumonia, Cellulitis, Anaemia, Respiratory Distress, Convulsion, Cholelithiasis, Joint Swelling, Impaired Gastric Emptying, Nephropathy, Synovial Rupture, Atelectasis, Constipation, Neuropathy Peripheral, Fatigue, Ileus, Pulmonary Congestion, Intervertebral Disc Degeneration, Dizziness, Pleural Effusion, Arteriovenous Fistula Thrombosis, Cholecystitis, Toothache, Thrombocytopenia, Azotaemia, Jugular Vein Thrombosis, Gastrooesophageal Reflux Disease, Blood Pressure Increased, Mitral Valve Disease, Bone Lesion, Nausea, Urinary Tract Infection, Osteolysis, Renal Failure Chronic, Rash Macular, Mucosal Inflammation, Osteoarthritis, Osteonecrosis of JAW, Diarrhoea, Sexual Dysfunction, Spinal Osteoarthritis, Superior Vena Cava Syndrome, Hypertension, Deep Vein Thrombosis, Infectious Peritonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Amitriptyline HCL; Acetaminophen; Omeprazole; Adriamycin PFS; Dexamethasone; Velcade; Methadone HCL; Epogen; Coumadin; Thalidomide; Prednisone; Nitroglycerin; Ativan; Melphalan Hydrochloride; Daily-Vite; MS Contin; Megace; Reglan; Citanest; Trimox; Oxycontin; Protonix; Colace; Remeron; Compazine; Zofran; Toprol-XL; Hematopoetic Progenitor Cells Human; Lopressor; Plavix; Paxil; Vincristine; Morphine; Vasotec; Senokot; Aspirin; Folic Acid; Lidocaine HCL
Possible Septocaine side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-14
Patient: female
Reactions: Confusional State, Activities of Daily Living Impaired, Dementia, Disorientation
Drug(s) suspected as cause:
Septocaine
Possible Septocaine side effects in male
Reported by a lawyer from United States on 2011-11-10
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Abdominal Pain, Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Oedema Peripheral, Vascular Pseudoaneurysm, Endocarditis, Vertebral Foraminal Stenosis, Staphylococcal Bacteraemia, Cervical Spinal Stenosis, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Osteoporosis, Hepatitis C, Chills, Mental Status Changes, Wound Decomposition, Multiple Myeloma, Kyphosis, Tooth Discolouration, Chest Pain, Oedema, Bone Disorder, Decreased Appetite, Device Related Sepsis, Fluid Overload, Vomiting, Gouty Arthritis, Viral Infection, Dyspnoea, Cataract, Ear Infection, Febrile Neutropenia, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Asthenia, Lung Infiltration, Hyperthyroidism, Weight Decreased, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Device Related Infection, Pyrexia, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Cardiac Failure Congestive, Progressive Supranuclear Palsy, Pneumonia, Cellulitis, Anaemia, Respiratory Distress, Convulsion, Cholelithiasis, Joint Swelling, Impaired Gastric Emptying, Nephropathy, Atelectasis, Synovial Rupture, Constipation, Neuropathy Peripheral, Fatigue, Ileus, Pulmonary Congestion, Pleural Effusion, Intervertebral Disc Degeneration, Dizziness, Cholecystitis, Toothache, Arteriovenous Fistula Thrombosis, Azotaemia, Thrombocytopenia, Jugular Vein Thrombosis, Gastrooesophageal Reflux Disease, Blood Pressure Increased, Mitral Valve Disease, Nausea, Bone Lesion, Urinary Tract Infection, Osteolysis, Renal Failure Chronic, Rash Macular, Mucosal Inflammation, Osteoarthritis, Osteonecrosis of JAW, Diarrhoea, Sexual Dysfunction, Spinal Osteoarthritis, Superior Vena Cava Syndrome, Hypertension, Deep Vein Thrombosis, Infectious Peritonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: MS Contin; Toprol-XL; Folic Acid; Colace; Ativan; Coumadin; Nitroglycerin; Lidocaine HCL; Adriamycin PFS; Thalidomide; Remeron; Oxycontin; Vasotec; Hematopoetic Progenitor Cells Human; Vincristine; Dexamethasone; Compazine; Melphalan Hydrochloride; Paxil; Methadone HCL; Zofran; Acetaminophen; Citanest; Amitriptyline HCL; Megace; Plavix; Morphine; Epogen; Protonix; Lopressor; Aspirin; Velcade; Prednisone TAB; Senokot; Reglan; Trimox
Possible Septocaine side effects in male
Reported by a physician from United States on 2011-11-01
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Vascular Pseudoaneurysm, Endocarditis, Vertebral Foraminal Stenosis, Staphylococcal Bacteraemia, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Hepatitis C, Osteoporosis, Chills, Mental Status Changes, Wound Decomposition, Multiple Myeloma, Kyphosis, Tooth Discolouration, Chest Pain, Oedema, Bone Disorder, Decreased Appetite, Fluid Overload, Device Related Sepsis, Gouty Arthritis, Cataract, Viral Infection, Vomiting, Dyspnoea, Ear Infection, Febrile Neutropenia, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Asthenia, Hyperthyroidism, Weight Decreased, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Device Related Infection, Pyrexia, Erectile Dysfunction, Gynaecomastia, Sedation, Hypoxia, Cardiac Failure Congestive, Progressive Supranuclear Palsy, Pneumonia, Cellulitis, Anaemia, Convulsion, Impaired Gastric Emptying, Nephropathy, Atelectasis, Constipation, Neuropathy Peripheral, Fatigue, Dizziness, Pleural Effusion, Intervertebral Disc Degeneration, Toothache, Arteriovenous Fistula Thrombosis, Cholecystitis, Thrombocytopenia, Jugular Vein Thrombosis, Azotaemia, Gastrooesophageal Reflux Disease, Blood Pressure Increased, Mitral Valve Disease, Bone Lesion, Nausea, Urinary Tract Infection, Osteolysis, Renal Failure Chronic, Rash Macular, Mucosal Inflammation, Diarrhoea, Osteonecrosis of JAW, Sexual Dysfunction, Hypertension, Superior Vena Cava Syndrome, Deep Vein Thrombosis, Infectious Peritonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Amitriptyline HCL; Epogen; Nitroglycerin; Hematopoetic Progenitor Cells Human; Methadone HCL; Megace; Oxycontin; Senokot; Lidocaine HCL; MS Contin; Toprol-XL; Tylenol-500; Dexamethasone; Thalidomide; Morphine; Prednisone; Trimox; Vincristine; Zofran; Protonix; Ativan; Melphalan Hydrochloride; Lopressor; Paxil; Reglan; Coumadin; Plavix; Adriamycin PFS; Remeron; Compazine; Vasotec; Colace; Velcade; Folic Acid; Aspirin; Citanest
Possible Septocaine side effects in male
Reported by a physician from United States on 2011-10-18
Patient: male, weighing 59.0 kg (129.8 pounds)
Reactions: Tachycardia, Dental Plaque, Arteriovenous Fistula Occlusion, Endocarditis, Vertebral Foraminal Stenosis, Staphylococcal Bacteraemia, Immunosuppression, Back Pain, Aeromona Infection, Dyspnoea Paroxysmal Nocturnal, Pancytopenia, Osteopenia, Compression Fracture, Hepatitis C, Osteoporosis, Chills, Mental Status Changes, Wound Decomposition, Multiple Myeloma, Kyphosis, Chest Pain, Tooth Discolouration, Oedema, Bone Disorder, Decreased Appetite, Fluid Overload, Device Related Sepsis, Viral Infection, Cataract, Gouty Arthritis, Vomiting, Dyspnoea, Febrile Neutropenia, Ear Infection, Hypophosphataemia, Conjunctival Haemorrhage, Sepsis, Hyperthyroidism, Asthenia, Weight Decreased, Gastrointestinal Haemorrhage, Hyperkalaemia, Clostridium Difficile Colitis, Pyrexia, Device Related Infection, Sedation, Hypoxia, Cardiac Failure Congestive, Progressive Supranuclear Palsy, Pneumonia, Cellulitis, Anaemia, Convulsion, Impaired Gastric Emptying, Nephropathy, Atelectasis, Constipation, Neuropathy Peripheral, Fatigue, Intervertebral Disc Degeneration, Dizziness, Pleural Effusion, Toothache, Cholecystitis, Azotaemia, Thrombocytopenia, Gastrooesophageal Reflux Disease, Blood Pressure Increased, Mitral Valve Disease, Nausea, Bone Lesion, Urinary Tract Infection, Osteolysis, Renal Failure Chronic, Rash Macular, Mucosal Inflammation, Diarrhoea, Osteonecrosis of JAW, Sexual Dysfunction, Hypertension, Deep Vein Thrombosis, Infectious Peritonitis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aredia
Dosage: 60 mg, qmo
Indication: Multiple Myeloma
Septocaine
Zometa
Dosage: 4 mg, qmo
Indication: Multiple Myeloma
End date: 2005-05-19
Other drugs received by patient: Epogen; Compazine; Protonix; Colace; Hematopoetic Progenitor Cells Human; Lopressor; Aspirin; Vincristine; Velcade; Morphine; Remeron; Prednisone; Toprol-XL; Folic Acid; Reglan; Paxil; Citanest; Thalidomide; Amitriptyline HCL; Methadone HCL; Megace; Zofran; Coumadin; Dexamethasone; MS Contin; Nitroglycerin; Oxycontin; Adriamycin PFS; Ativan; Plavix; Lidocaine HCL; Trimox; Vasotec; Tylenol-500; Senokot; Melphalan Hydrochloride
Possible Septocaine side effects in male
Reported by a physician from United States on 2011-10-07
Patient: male
Reactions: Myalgia, Trismus, Post Procedural Complication, Dysaesthesia
Drug(s) suspected as cause:
Septocaine
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