Index of reports
> Cases with Febrile Neutropenia (15)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Rituxan (Rituximab) where reactions include febrile neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Rituxan side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-15
Patient: male, weighing 91.7 kg (201.7 pounds)
Reactions: Pneumonia, Anaemia, Pancytopenia, Febrile Neutropenia, Respiratory Failure, Muscle Abscess, Thrombocytopenia, Cardiac Arrest
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Rituxan
Dosage: 150 milligram
Start date: 2012-05-14
Vidaza
Dosage: 150 milligram
Start date: 2012-05-14
Rituxan
Start date: 2012-06-22
Vidaza
Dosage: 150 milligram
Start date: 2012-07-19
End date: 2012-07-20
Rituxan
Start date: 2012-07-19
End date: 2012-07-20
Rituxan
Dosage: 17.8571 milligram
Start date: 2012-08-04
Other drugs received by patient: Procrit; Fluticasone Propionate; Folic Acid; Hydrocortisone-Pramoxine; Metoprolol Tartrate; Rosuvastatin; Meropenem; Vancomycin; Dextrose; Acetaminophen; Calcium + Vitamin D; Ciprofloxacin-Dexamethasone Otic; Diphenhydramine Hydrochloride; Filgrastim; Multi-Vitamins; Phenylephrine Hydrochloride; Acetaminophen; Naproxen; Whole Blood; Prednisone TAB; Vitamin B-12; Acetaminophen; Benazepril Hydrochloride; Augmentin '500'; Amlodipine; Omeprazole; Sodium Chloride
Possible Rituxan side effects in 68 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-13
Patient: 68 year old male, weighing 93.4 kg (205.6 pounds)
Reactions: Dyspnoea, Musculoskeletal Pain, Pancytopenia, Febrile Neutropenia, Cough
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Vidaza
Vidaza
Dosage: 150 milligram
Start date: 2012-05-14
Rituxan
Dosage: 750 milligram
Start date: 2012-06-22
Rituxan
Possible Rituxan side effects in 46 year old male
Reported by a physician from United States on 2012-07-12
Patient: 46 year old male
Reactions: Febrile Neutropenia, Deep Vein Thrombosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rituxan
Dosage: 698 mg, unk
Start date: 2012-05-02
Mesna
Dosage: 1116 mg, unk
Indication: non-Hodgkin's Lymphoma
Cyclophosphamide
Dosage: 446 mg, unk
Doxorubicin HCL
Dosage: 56.5 mg, unk
Indication: non-Hodgkin's Lymphoma
Start date: 2012-02-17
End date: 2012-02-22
Pegfilgrastim
Dosage: 6 mg, unk
Indication: non-Hodgkin's Lymphoma
Cyclophosphamide
Dosage: 630 mg, q12h
Indication: non-Hodgkin's Lymphoma
Start date: 2012-02-17
End date: 2012-02-22
Vincristine Sulfate
Dosage: 2 mg, unk
Indication: non-Hodgkin's Lymphoma
Start date: 2012-02-17
Doxorubicin HCL
Dosage: 37 mg, unk
Dexamethasone
Dosage: 40 mg, unk
Administration route: Oral
Indication: non-Hodgkin's Lymphoma
Start date: 2012-02-17
Rituxan
Dosage: 787.5 mg, unk
Indication: non-Hodgkin's Lymphoma
Start date: 2012-02-17
End date: 2012-02-22
Other drugs received by patient: MS Contin; Valtrex; Omeprazole; Ciprofloxacin; Morphine Sulfate; Enoxaparin / 01708202 /; Compazine; Fluconazole; Metoprolol Tartrate
Possible Rituxan side effects in 62 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-21
Patient: 62 year old male, weighing 120.3 kg (264.7 pounds)
Reactions: Febrile Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Bendamustine Hydrochloride
Dosage: 160-200mg
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-03-09
Rituxan
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-03-09
Possible Rituxan side effects in 54 year old female
Reported by a physician from Taiwan, Province of China on 2012-05-14
Patient: 54 year old female, weighing 58.4 kg (128.5 pounds)
Reactions: Febrile Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cytosar-U
Dosage: 3000 mg, 1x/day
Indication: non-Hodgkin's Lymphoma
Start date: 2012-03-07
Vepesid
Dosage: 65 mg, 1x/day
Indication: non-Hodgkin's Lymphoma
Start date: 2012-03-03
Solu-Medrol
Dosage: 500 mg, 1x/day
Indication: non-Hodgkin's Lymphoma
Start date: 2012-03-03
Rituxan
Dosage: 577.5 mg, cyclic, day 1 of each 28 day cycle
Indication: non-Hodgkin's Lymphoma
Start date: 2012-01-05
End date: 2012-02-02
Inotuzumab Ozogamicin
Dosage: 2.77 mg, cyclic, day 2 of each 28 day cycle
Indication: non-Hodgkin's Lymphoma
Start date: 2012-01-06
End date: 2012-02-03
Abiplatin
Dosage: 40 mg, 1x/day
Indication: non-Hodgkin's Lymphoma
Start date: 2012-03-03
Other drugs received by patient: Aloxi; Ultracet; Senokot; Norvasc; Chlorhexidine; Vitamin B6
Possible Rituxan side effects in 61 year old male
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-05-11
Patient: 61 year old male, weighing 124.0 kg (272.8 pounds)
Reactions: Pneumonia Primary Atypical, Febrile Neutropenia, Septic Shock, Respiratory Syncytial Virus Infection
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Bendamustine Hydrochloride
Dosage: 127 milligram
Indication: Chronic Lymphocytic Leukaemia
Start date: 2012-03-15
End date: 2012-03-15
Revlimid
Dosage: 25 milligram
Administration route: Oral
Indication: Chronic Lymphocytic Leukaemia
Start date: 2012-03-15
End date: 2012-04-11
Rituxan
Dosage: 953.9 milligram
Indication: Chronic Lymphocytic Leukaemia
Start date: 2012-03-14
End date: 2012-03-14
Other drugs received by patient: Hydrochlorothiazide; Tamsulosin HCL; Gabapentin; Rifabutin; Ethambutol Hydrochloride; Amphotericin B; Indapamid; Candesartan Cilexetil; Tiotropium; Fluticasone Propionate / Salmeterol; Pantoprazole; Amlodipine Besylate; Torsemide; Acetylsalicylic Acid SRT; Metoprolol Tartrate; Tilidin Plus; Rifabutin; Metformin HCL; Clarithromycin; Digitoxin TAB
Possible Rituxan side effects in male
Reported by a physician from Romania on 2012-05-10
Patient: male, weighing 55.0 kg (121.0 pounds)
Reactions: Sepsis, Febrile Neutropenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Rituxan
Indication: Mantle Cell Lymphoma
Start date: 2011-12-28
End date: 2012-04-24
Fludarabine Phosphate
Indication: Mantle Cell Lymphoma
Other drugs received by patient: Acidum Ursodeoxycholicum; Vitamin B6; Arginin; Acyclovir; Silibinin; Acid Folic; Cotrim; Allopurinol
Possible Rituxan side effects in 55 year old male
Reported by a physician from United States on 2012-04-24
Patient: 55 year old male, weighing 92.0 kg (202.4 pounds)
Reactions: White Blood Cell Count Decreased, Febrile Neutropenia, Toxicity To Various Agents, Perirectal Abscess, Rash Macular, Haemoglobin Decreased, Stem Cell Transplant, Haematocrit Decreased, Catheter Site Erythema, Diarrhoea, Hypophagia, Catheter Site Related Reaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Zevalin
Dosage: 4.6 mci, single, intravenous (not otherwise specified)
Indication: Multiple Myeloma
Start date: 2011-05-03
End date: 2011-05-03
Cefepime
Dosage: 2 g, tid, intravenous (not otherwise specified)
Indication: Pyrexia
Start date: 2011-06-03
End date: 2011-06-06
Rituxan
Dosage: 200 mg, single
Indication: Multiple Myeloma
Start date: 2011-05-12
End date: 2011-05-12
Meropenem
Dosage: 1 g, qd, intravenous (not otherwise specified)
Indication: Pyrexia
Start date: 2011-06-06
End date: 2011-06-18
Metronidazole
Dosage: 500 mg, tid, oral
Administration route: Oral
Indication: Prophylaxis
Start date: 2011-06-04
End date: 2011-06-05
Other drugs received by patient: (Famvir / 01226201 / ); Ativan; Allopurinol; Colchicine; Neurontin; Dilaudid; Seroquel; Aspirin; Fentanyl Citrate; Atenolol
Possible Rituxan side effects in
Reported by a consumer/non-health professional from United States on 2012-04-24
Patient:
Reactions: White Blood Cell Count Decreased, Diarrhoea, Hypophagia, Febrile Neutropenia, Perirectal Abscess, Rash Macular
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Metronidazole
Dosage: unk, unknown
Zevalin
Dosage: 4.6 mci, single
Start date: 2011-05-03
End date: 2011-05-03
Metronidazole
Dosage: 500 mg, tid
Administration route: Oral
Indication: Pyrexia
Start date: 2011-06-04
End date: 2011-06-05
Zevalin
Dosage: 31.6 mci, single
Indication: Multiple Myeloma
Start date: 2011-05-12
End date: 2011-05-12
Meropenem
Dosage: 1 g, qd
Indication: Pyrexia
Start date: 2011-06-06
End date: 2011-06-18
Rituxan
Dosage: 200 mg, single
Indication: Multiple Myeloma
Start date: 2011-05-03
End date: 2011-05-03
Rituxan
Dosage: 200 mg, single
Start date: 2011-05-12
End date: 2011-05-12
Cefepime
Dosage: 2 g, tid
Indication: Pyrexia
Start date: 2011-06-03
End date: 2011-06-06
Other drugs received by patient: Atenolol; Neupogen; Fentanyl; Allopurinol; Colchicine; Aspirin; Famvir / 01226201 /; Seroquel; Dilaudid; Vancomycin; Neurontin; Vancomycin; Aztreonam; Ciprofloxacin; Ativan
Possible Rituxan side effects in male
Reported by a consumer/non-health professional from United States on 2012-04-19
Patient: male, weighing 92.0 kg (202.4 pounds)
Reactions: Injection Site Erythema, Diarrhoea, Hypophagia, Febrile Neutropenia, Injection Site Warmth, Perirectal Abscess, Rash Macular
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Metronidazole
Dosage: 500 mg, tid
Administration route: Oral
Indication: Prophylaxis
Start date: 2011-06-04
End date: 2011-06-05
Meropenem
Dosage: 1 g, qd
Indication: Pyrexia
Start date: 2011-06-06
End date: 2011-06-18
Rituxan
Dosage: 200 mg, once/single
Indication: Multiple Myeloma
Start date: 2011-05-12
End date: 2011-05-12
Cefepime
Dosage: 2 g, tid
Indication: Pyrexia
Start date: 2011-06-03
End date: 2011-06-06
Zevalin
Dosage: 31.6 mci, once/single
Indication: Multiple Myeloma
Start date: 2011-05-12
End date: 2011-05-12
Zevalin
Dosage: 4.6 mci, once/single
Start date: 2011-05-03
End date: 2011-05-03
Rituxan
Dosage: 200 mg, once/single
Start date: 2011-05-03
End date: 2011-05-03
Other drugs received by patient: Seroquel; Colchicine; Neurontin; Neupogen; Famvir; Vancomycin; Micafungin; Aspirin; Melphalan Hydrochloride; Dilaudid; Fentanyl; Atenolol; Vancomycin; Allopurinol; Ativan
Possible Rituxan side effects in male
Reported by a physician from Italy on 2012-02-27
Patient: male
Reactions: Hyperpyrexia, Febrile Neutropenia, Rash
Drug(s) suspected as cause:
Fludarabine Phosphate
Indication: Chronic Lymphocytic Leukaemia
End date: 2011-12-30
Cyclophosphamide
Indication: Chronic Lymphocytic Leukaemia
End date: 2011-12-30
Rituxan
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-10-14
End date: 2011-12-29
Other drugs received by patient: Acetaminophen; Methylprednisolone; Zofran; Trimeton; Lyrica; Allopurinol; Omeprazole; Hydrocortisone; Acyclovir
Possible Rituxan side effects in 61 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-01-11
Patient: 61 year old female
Reactions: Agranulocytosis, Febrile Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Noxafil
Dosage: 200 mg;tid;po
Administration route: Oral
Indication: Antifungal Prophylaxis
Start date: 2011-09-22
End date: 2011-12-05
Bactrim
Dosage: 800 mg;tiw;po
Administration route: Oral
Indication: Antibiotic Prophylaxis
Start date: 2011-09-22
End date: 2011-12-05
Rituxan
Dosage: 1000 mg;iv
Indication: Antisynthetase Syndrome
Start date: 2011-11-15
End date: 2011-12-01
Other drugs received by patient: Deroxat; Kayexalate; Folic Acid; Calcium; Aldacton; Previscan; Digoxin; Perdnisone; Acetaminophen; Nexium; Phenoxymethyl Penicillin; Valsartan
Possible Rituxan side effects in female
Reported by a physician from United States on 2011-12-20
Patient: female, weighing 60.3 kg (132.7 pounds)
Reactions: Stomatitis, Neutrophil Count, Oral Infection, Lymphopenia, Febrile Neutropenia, Transaminases Increased, Lymphocyte Count, Aspartate Aminotransferase Increased, Hypocalcaemia, Thrombocytopenia, Candidiasis, Leukopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Rituxan
Dosage: 820 mg
Start date: 2009-10-12
Leucovorin Calcium
Indication: Burkitt's Lymphoma Stage IV
Rituxan
Start date: 2009-11-30
Cyclophosphamide
Dosage: 328mg
Start date: 2009-10-14
End date: 2009-10-17
Vincristine
Methotrexate
Dosage: 4918mg
Indication: Burkitt's Lymphoma Stage IV
Start date: 2009-10-22
Methotrexate
Start date: 2009-08-26
Ifosfamide
Indication: Burkitt's Lymphoma Stage IV
End date: 2009-11-30
Ifosfamide
Ifosfamide
Ifosfamide
Start date: 2009-08-14
Etoposide
End date: 2009-11-30
Filgrastim
Filgrastim
Rituxan
Dosage: 825 mg
Indication: Burkitt's Lymphoma Stage IV
Start date: 2009-08-14
Cytarabine
Leucovorin Calcium
Start date: 2009-08-14
Filgrastim
Indication: Burkitt's Lymphoma Stage IV
End date: 2009-11-30
Doxorubicin HCL
Dosage: 66 mg
Indication: Burkitt's Lymphoma Stage IV
Start date: 2009-08-14
Etoposide
Indication: Burkitt's Lymphoma Stage IV
Doxorubicin HCL
End date: 2009-11-30
Rituxan
Dosage: 825 mg
Start date: 2009-08-24
Cyclophosphamide
Dosage: 1312mg
Indication: Burkitt's Lymphoma Stage IV
Start date: 2009-10-13
Methotrexate
End date: 2009-11-30
Etoposide
Doxorubicin HCL
Cyclophosphamide
Start date: 2009-08-16
End date: 2009-08-19
Vincristine
Dosage: 2mg
Indication: Burkitt's Lymphoma Stage IV
Start date: 2009-10-13
Vincristine
Dosage: 2mg
Start date: 2009-08-14
Vincristine
End date: 2009-11-30
Cytarabine
Indication: Burkitt's Lymphoma Stage IV
End date: 2009-11-30
Cytarabine
Etoposide
Start date: 2009-08-14
Filgrastim
Start date: 2009-08-14
Doxorubicin HCL
Dosage: 49mg, cycle 3
Start date: 2009-10-13
Rituxan
Dosage: 820 mg
Start date: 2009-10-20
Cyclophosphamide
Dosage: 1320mg
Start date: 2009-08-14
Cyclophosphamide
End date: 2009-11-30
Cytarabine
Start date: 2009-08-15
Leucovorin Calcium
Methotrexate
Dosage: 500 mg
Start date: 2009-08-14
Leucovorin Calcium
End date: 2009-11-30
Other drugs received by patient: Benadryl; Sodium Chloride; Colace; Colace; Nystatin; Dextrose; Acetaminophen; Piperacillin; Lisinopril; Tazobactam; Allopurinol; Acyclovir; Fluconazole; Sodium Bicarbonate; Vancomycin Hychloride; Dapsone
Possible Rituxan side effects in 58 year old female
Reported by a consumer/non-health professional from United States on 2011-11-23
Patient: 58 year old female
Reactions: Tumour Lysis Syndrome, Urinary Tract Infection, Pancytopenia, Febrile Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cytoxan
Dosage: d1-3. q28d
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-07-26
End date: 2011-07-26
Fludarabine Phosphate
Dosage: d1-3.q28d
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-07-26
End date: 2011-07-26
Rituxan
Dosage: d1 q28d
Indication: Chronic Lymphocytic Leukaemia
Start date: 2011-07-26
End date: 2011-07-26
Possible Rituxan side effects in female
Reported by a physician from Japan on 2011-10-10
Patient: female, weighing 49.0 kg (107.8 pounds)
Reactions: Viral Haemorrhagic Cystitis, C-Reactive Protein Increased, Diarrhoea, RED Blood Cells Urine Positive, Cytomegalovirus Viraemia, Febrile Neutropenia, Blood Immunoglobulin G Decreased, Hypokalaemia
Drug(s) suspected as cause:
Alkeran
Dosage: 130mgm2 per day
Indication: Stem Cell Transplant
Start date: 2010-10-14
End date: 2010-10-14
Etoposide
Dosage: 500mgm2 per day
Indication: Stem Cell Transplant
Start date: 2010-10-11
End date: 2010-10-13
Cyclophosphamide
Dosage: 60mgk per day
Indication: Stem Cell Transplant
Start date: 2010-10-11
End date: 2010-10-12
Rituxan
Dosage: 375mgm2 per day
Indication: Stem Cell Transplant
Start date: 2010-10-10
End date: 2010-10-10
Other drugs received by patient: Bactrim; Emend; BIO Three; Urso 250; Bactrim; Fluconazole; Emend; Famotidine; Mucosta; Ciprofloxacin HCL
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