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Rituxan (Rituximab) - Febrile Neutropenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Febrile Neutropenia (15)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Rituxan (Rituximab) where reactions include febrile neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Rituxan side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-15

Patient: male, weighing 91.7 kg (201.7 pounds)

Reactions: Pneumonia, Anaemia, Pancytopenia, Febrile Neutropenia, Respiratory Failure, Muscle Abscess, Thrombocytopenia, Cardiac Arrest

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Rituxan
    Dosage: 150 milligram
    Start date: 2012-05-14

Vidaza
    Dosage: 150 milligram
    Start date: 2012-05-14

Rituxan
    Start date: 2012-06-22

Vidaza
    Dosage: 150 milligram
    Start date: 2012-07-19
    End date: 2012-07-20

Rituxan
    Start date: 2012-07-19
    End date: 2012-07-20

Rituxan
    Dosage: 17.8571 milligram
    Start date: 2012-08-04

Other drugs received by patient: Procrit; Fluticasone Propionate; Folic Acid; Hydrocortisone-Pramoxine; Metoprolol Tartrate; Rosuvastatin; Meropenem; Vancomycin; Dextrose; Acetaminophen; Calcium + Vitamin D; Ciprofloxacin-Dexamethasone Otic; Diphenhydramine Hydrochloride; Filgrastim; Multi-Vitamins; Phenylephrine Hydrochloride; Acetaminophen; Naproxen; Whole Blood; Prednisone TAB; Vitamin B-12; Acetaminophen; Benazepril Hydrochloride; Augmentin '500'; Amlodipine; Omeprazole; Sodium Chloride



Possible Rituxan side effects in 68 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-13

Patient: 68 year old male, weighing 93.4 kg (205.6 pounds)

Reactions: Dyspnoea, Musculoskeletal Pain, Pancytopenia, Febrile Neutropenia, Cough

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vidaza

Vidaza
    Dosage: 150 milligram
    Start date: 2012-05-14

Rituxan
    Dosage: 750 milligram
    Start date: 2012-06-22

Rituxan



Possible Rituxan side effects in 46 year old male

Reported by a physician from United States on 2012-07-12

Patient: 46 year old male

Reactions: Febrile Neutropenia, Deep Vein Thrombosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rituxan
    Dosage: 698 mg, unk
    Start date: 2012-05-02

Mesna
    Dosage: 1116 mg, unk
    Indication: non-Hodgkin's Lymphoma

Cyclophosphamide
    Dosage: 446 mg, unk

Doxorubicin HCL
    Dosage: 56.5 mg, unk
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17
    End date: 2012-02-22

Pegfilgrastim
    Dosage: 6 mg, unk
    Indication: non-Hodgkin's Lymphoma

Cyclophosphamide
    Dosage: 630 mg, q12h
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17
    End date: 2012-02-22

Vincristine Sulfate
    Dosage: 2 mg, unk
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17

Doxorubicin HCL
    Dosage: 37 mg, unk

Dexamethasone
    Dosage: 40 mg, unk
    Administration route: Oral
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17

Rituxan
    Dosage: 787.5 mg, unk
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-02-17
    End date: 2012-02-22

Other drugs received by patient: MS Contin; Valtrex; Omeprazole; Ciprofloxacin; Morphine Sulfate; Enoxaparin / 01708202 /; Compazine; Fluconazole; Metoprolol Tartrate



Possible Rituxan side effects in 62 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-21

Patient: 62 year old male, weighing 120.3 kg (264.7 pounds)

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bendamustine Hydrochloride
    Dosage: 160-200mg
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-03-09

Rituxan
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-03-09



Possible Rituxan side effects in 54 year old female

Reported by a physician from Taiwan, Province of China on 2012-05-14

Patient: 54 year old female, weighing 58.4 kg (128.5 pounds)

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cytosar-U
    Dosage: 3000 mg, 1x/day
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-03-07

Vepesid
    Dosage: 65 mg, 1x/day
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-03-03

Solu-Medrol
    Dosage: 500 mg, 1x/day
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-03-03

Rituxan
    Dosage: 577.5 mg, cyclic, day 1 of each 28 day cycle
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-01-05
    End date: 2012-02-02

Inotuzumab Ozogamicin
    Dosage: 2.77 mg, cyclic, day 2 of each 28 day cycle
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-01-06
    End date: 2012-02-03

Abiplatin
    Dosage: 40 mg, 1x/day
    Indication: non-Hodgkin's Lymphoma
    Start date: 2012-03-03

Other drugs received by patient: Aloxi; Ultracet; Senokot; Norvasc; Chlorhexidine; Vitamin B6



Possible Rituxan side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-05-11

Patient: 61 year old male, weighing 124.0 kg (272.8 pounds)

Reactions: Pneumonia Primary Atypical, Febrile Neutropenia, Septic Shock, Respiratory Syncytial Virus Infection

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Bendamustine Hydrochloride
    Dosage: 127 milligram
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-03-15
    End date: 2012-03-15

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-03-15
    End date: 2012-04-11

Rituxan
    Dosage: 953.9 milligram
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2012-03-14
    End date: 2012-03-14

Other drugs received by patient: Hydrochlorothiazide; Tamsulosin HCL; Gabapentin; Rifabutin; Ethambutol Hydrochloride; Amphotericin B; Indapamid; Candesartan Cilexetil; Tiotropium; Fluticasone Propionate / Salmeterol; Pantoprazole; Amlodipine Besylate; Torsemide; Acetylsalicylic Acid SRT; Metoprolol Tartrate; Tilidin Plus; Rifabutin; Metformin HCL; Clarithromycin; Digitoxin TAB



Possible Rituxan side effects in male

Reported by a physician from Romania on 2012-05-10

Patient: male, weighing 55.0 kg (121.0 pounds)

Reactions: Sepsis, Febrile Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Rituxan
    Indication: Mantle Cell Lymphoma
    Start date: 2011-12-28
    End date: 2012-04-24

Fludarabine Phosphate
    Indication: Mantle Cell Lymphoma

Other drugs received by patient: Acidum Ursodeoxycholicum; Vitamin B6; Arginin; Acyclovir; Silibinin; Acid Folic; Cotrim; Allopurinol



Possible Rituxan side effects in

Reported by a consumer/non-health professional from United States on 2012-04-24

Patient:

Reactions: White Blood Cell Count Decreased, Diarrhoea, Hypophagia, Febrile Neutropenia, Perirectal Abscess, Rash Macular

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Metronidazole
    Dosage: unk, unknown

Zevalin
    Dosage: 4.6 mci, single
    Start date: 2011-05-03
    End date: 2011-05-03

Metronidazole
    Dosage: 500 mg, tid
    Administration route: Oral
    Indication: Pyrexia
    Start date: 2011-06-04
    End date: 2011-06-05

Zevalin
    Dosage: 31.6 mci, single
    Indication: Multiple Myeloma
    Start date: 2011-05-12
    End date: 2011-05-12

Meropenem
    Dosage: 1 g, qd
    Indication: Pyrexia
    Start date: 2011-06-06
    End date: 2011-06-18

Rituxan
    Dosage: 200 mg, single
    Indication: Multiple Myeloma
    Start date: 2011-05-03
    End date: 2011-05-03

Rituxan
    Dosage: 200 mg, single
    Start date: 2011-05-12
    End date: 2011-05-12

Cefepime
    Dosage: 2 g, tid
    Indication: Pyrexia
    Start date: 2011-06-03
    End date: 2011-06-06

Other drugs received by patient: Atenolol; Neupogen; Fentanyl; Allopurinol; Colchicine; Aspirin; Famvir / 01226201 /; Seroquel; Dilaudid; Vancomycin; Neurontin; Vancomycin; Aztreonam; Ciprofloxacin; Ativan



Possible Rituxan side effects in 55 year old male

Reported by a physician from United States on 2012-04-24

Patient: 55 year old male, weighing 92.0 kg (202.4 pounds)

Reactions: White Blood Cell Count Decreased, Febrile Neutropenia, Toxicity To Various Agents, Perirectal Abscess, Rash Macular, Haemoglobin Decreased, Stem Cell Transplant, Haematocrit Decreased, Catheter Site Erythema, Diarrhoea, Hypophagia, Catheter Site Related Reaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zevalin
    Dosage: 4.6 mci, single, intravenous (not otherwise specified)
    Indication: Multiple Myeloma
    Start date: 2011-05-03
    End date: 2011-05-03

Cefepime
    Dosage: 2 g, tid, intravenous (not otherwise specified)
    Indication: Pyrexia
    Start date: 2011-06-03
    End date: 2011-06-06

Rituxan
    Dosage: 200 mg, single
    Indication: Multiple Myeloma
    Start date: 2011-05-12
    End date: 2011-05-12

Meropenem
    Dosage: 1 g, qd, intravenous (not otherwise specified)
    Indication: Pyrexia
    Start date: 2011-06-06
    End date: 2011-06-18

Metronidazole
    Dosage: 500 mg, tid, oral
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2011-06-04
    End date: 2011-06-05

Other drugs received by patient: (Famvir / 01226201 / ); Ativan; Allopurinol; Colchicine; Neurontin; Dilaudid; Seroquel; Aspirin; Fentanyl Citrate; Atenolol



Possible Rituxan side effects in male

Reported by a consumer/non-health professional from United States on 2012-04-19

Patient: male, weighing 92.0 kg (202.4 pounds)

Reactions: Injection Site Erythema, Diarrhoea, Hypophagia, Febrile Neutropenia, Injection Site Warmth, Perirectal Abscess, Rash Macular

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Metronidazole
    Dosage: 500 mg, tid
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2011-06-04
    End date: 2011-06-05

Meropenem
    Dosage: 1 g, qd
    Indication: Pyrexia
    Start date: 2011-06-06
    End date: 2011-06-18

Rituxan
    Dosage: 200 mg, once/single
    Indication: Multiple Myeloma
    Start date: 2011-05-12
    End date: 2011-05-12

Cefepime
    Dosage: 2 g, tid
    Indication: Pyrexia
    Start date: 2011-06-03
    End date: 2011-06-06

Zevalin
    Dosage: 31.6 mci, once/single
    Indication: Multiple Myeloma
    Start date: 2011-05-12
    End date: 2011-05-12

Zevalin
    Dosage: 4.6 mci, once/single
    Start date: 2011-05-03
    End date: 2011-05-03

Rituxan
    Dosage: 200 mg, once/single
    Start date: 2011-05-03
    End date: 2011-05-03

Other drugs received by patient: Seroquel; Colchicine; Neurontin; Neupogen; Famvir; Vancomycin; Micafungin; Aspirin; Melphalan Hydrochloride; Dilaudid; Fentanyl; Atenolol; Vancomycin; Allopurinol; Ativan



Possible Rituxan side effects in male

Reported by a physician from Italy on 2012-02-27

Patient: male

Reactions: Hyperpyrexia, Febrile Neutropenia, Rash

Drug(s) suspected as cause:
Fludarabine Phosphate
    Indication: Chronic Lymphocytic Leukaemia
    End date: 2011-12-30

Cyclophosphamide
    Indication: Chronic Lymphocytic Leukaemia
    End date: 2011-12-30

Rituxan
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-10-14
    End date: 2011-12-29

Other drugs received by patient: Acetaminophen; Methylprednisolone; Zofran; Trimeton; Lyrica; Allopurinol; Omeprazole; Hydrocortisone; Acyclovir



Possible Rituxan side effects in 61 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-11

Patient: 61 year old female

Reactions: Agranulocytosis, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Noxafil
    Dosage: 200 mg;tid;po
    Administration route: Oral
    Indication: Antifungal Prophylaxis
    Start date: 2011-09-22
    End date: 2011-12-05

Bactrim
    Dosage: 800 mg;tiw;po
    Administration route: Oral
    Indication: Antibiotic Prophylaxis
    Start date: 2011-09-22
    End date: 2011-12-05

Rituxan
    Dosage: 1000 mg;iv
    Indication: Antisynthetase Syndrome
    Start date: 2011-11-15
    End date: 2011-12-01

Other drugs received by patient: Deroxat; Kayexalate; Folic Acid; Calcium; Aldacton; Previscan; Digoxin; Perdnisone; Acetaminophen; Nexium; Phenoxymethyl Penicillin; Valsartan



Possible Rituxan side effects in female

Reported by a physician from United States on 2011-12-20

Patient: female, weighing 60.3 kg (132.7 pounds)

Reactions: Stomatitis, Neutrophil Count, Oral Infection, Lymphopenia, Febrile Neutropenia, Transaminases Increased, Lymphocyte Count, Aspartate Aminotransferase Increased, Hypocalcaemia, Thrombocytopenia, Candidiasis, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rituxan
    Dosage: 820 mg
    Start date: 2009-10-12

Leucovorin Calcium
    Indication: Burkitt's Lymphoma Stage IV

Rituxan
    Start date: 2009-11-30

Cyclophosphamide
    Dosage: 328mg
    Start date: 2009-10-14
    End date: 2009-10-17

Vincristine

Methotrexate
    Dosage: 4918mg
    Indication: Burkitt's Lymphoma Stage IV
    Start date: 2009-10-22

Methotrexate
    Start date: 2009-08-26

Ifosfamide
    Indication: Burkitt's Lymphoma Stage IV
    End date: 2009-11-30

Ifosfamide

Ifosfamide

Ifosfamide
    Start date: 2009-08-14

Etoposide
    End date: 2009-11-30

Filgrastim

Filgrastim

Rituxan
    Dosage: 825 mg
    Indication: Burkitt's Lymphoma Stage IV
    Start date: 2009-08-14

Cytarabine

Leucovorin Calcium
    Start date: 2009-08-14

Filgrastim
    Indication: Burkitt's Lymphoma Stage IV
    End date: 2009-11-30

Doxorubicin HCL
    Dosage: 66 mg
    Indication: Burkitt's Lymphoma Stage IV
    Start date: 2009-08-14

Etoposide
    Indication: Burkitt's Lymphoma Stage IV

Doxorubicin HCL
    End date: 2009-11-30

Rituxan
    Dosage: 825 mg
    Start date: 2009-08-24

Cyclophosphamide
    Dosage: 1312mg
    Indication: Burkitt's Lymphoma Stage IV
    Start date: 2009-10-13

Methotrexate
    End date: 2009-11-30

Etoposide

Doxorubicin HCL

Cyclophosphamide
    Start date: 2009-08-16
    End date: 2009-08-19

Vincristine
    Dosage: 2mg
    Indication: Burkitt's Lymphoma Stage IV
    Start date: 2009-10-13

Vincristine
    Dosage: 2mg
    Start date: 2009-08-14

Vincristine
    End date: 2009-11-30

Cytarabine
    Indication: Burkitt's Lymphoma Stage IV
    End date: 2009-11-30

Cytarabine

Etoposide
    Start date: 2009-08-14

Filgrastim
    Start date: 2009-08-14

Doxorubicin HCL
    Dosage: 49mg, cycle 3
    Start date: 2009-10-13

Rituxan
    Dosage: 820 mg
    Start date: 2009-10-20

Cyclophosphamide
    Dosage: 1320mg
    Start date: 2009-08-14

Cyclophosphamide
    End date: 2009-11-30

Cytarabine
    Start date: 2009-08-15

Leucovorin Calcium

Methotrexate
    Dosage: 500 mg
    Start date: 2009-08-14

Leucovorin Calcium
    End date: 2009-11-30

Other drugs received by patient: Benadryl; Sodium Chloride; Colace; Colace; Nystatin; Dextrose; Acetaminophen; Piperacillin; Lisinopril; Tazobactam; Allopurinol; Acyclovir; Fluconazole; Sodium Bicarbonate; Vancomycin Hychloride; Dapsone



Possible Rituxan side effects in 58 year old female

Reported by a consumer/non-health professional from United States on 2011-11-23

Patient: 58 year old female

Reactions: Tumour Lysis Syndrome, Urinary Tract Infection, Pancytopenia, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cytoxan
    Dosage: d1-3. q28d
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-07-26
    End date: 2011-07-26

Fludarabine Phosphate
    Dosage: d1-3.q28d
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-07-26
    End date: 2011-07-26

Rituxan
    Dosage: d1 q28d
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-07-26
    End date: 2011-07-26



Possible Rituxan side effects in female

Reported by a physician from Japan on 2011-10-10

Patient: female, weighing 49.0 kg (107.8 pounds)

Reactions: Viral Haemorrhagic Cystitis, C-Reactive Protein Increased, Diarrhoea, RED Blood Cells Urine Positive, Cytomegalovirus Viraemia, Febrile Neutropenia, Blood Immunoglobulin G Decreased, Hypokalaemia

Drug(s) suspected as cause:
Alkeran
    Dosage: 130mgm2 per day
    Indication: Stem Cell Transplant
    Start date: 2010-10-14
    End date: 2010-10-14

Etoposide
    Dosage: 500mgm2 per day
    Indication: Stem Cell Transplant
    Start date: 2010-10-11
    End date: 2010-10-13

Cyclophosphamide
    Dosage: 60mgk per day
    Indication: Stem Cell Transplant
    Start date: 2010-10-11
    End date: 2010-10-12

Rituxan
    Dosage: 375mgm2 per day
    Indication: Stem Cell Transplant
    Start date: 2010-10-10
    End date: 2010-10-10

Other drugs received by patient: Bactrim; Emend; BIO Three; Urso 250; Bactrim; Fluconazole; Emend; Famotidine; Mucosta; Ciprofloxacin HCL

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