Remicade (Infliximab) - Death - Suspected Cause - Side Effect Reports

Possible Remicade side effects in male

Reported by a consumer/non-health professional from Canada on 2012-08-27

Patient: male, weighing 99.8 kg (219.5 pounds)

Reactions: Death, Gastrointestinal Haemorrhage, Drug Ineffective

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade

Possible Remicade side effects in

Reported by a physician from United Kingdom on 2012-08-23

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Remicade

Possible Remicade side effects in male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-23

Patient: male, weighing 62.0 kg (136.4 pounds)

Reactions: Death, Gastrointestinal Infection, Lung Neoplasm Malignant, Cystitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade

Other drugs received by patient: Lorazepam; Flovent; Solu-Cortef; Spiriva; Symbicort

Possible Remicade side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-21

Patient: male, weighing 69.0 kg (151.8 pounds)

Reactions: Hepatosplenic T-Cell Lymphoma

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Colitis Ulcerative
    Start date: 2007-06-15

Humira
    Start date: 2007-06-15

Humira
    Start date: 2006-11-01

Humira
    Indication: Irritable Bowel Syndrome
    Start date: 2006-11-01

Purinethol
    Dosage: also reported with start date of 01-oct-1999
    Start date: 1999-06-02

Purinethol
    Dosage: also reported with start date of 01-oct-1999
    Start date: 1999-06-02

Purinethol
    Indication: Inflammatory Bowel Disease
    End date: 2007-04-01

Purinethol
    Indication: Colitis Ulcerative
    End date: 2007-04-01

Remicade
    Dosage: 19 infusions administered between 10-jul-2002 and 7-mar-2006
    Indication: Inflammatory Bowel Disease
    Start date: 2002-07-10
    End date: 2006-03-07

Remicade
    Dosage: 19 infusions administered between 10-jul-2002 and 7-mar-2006
    Indication: Colitis Ulcerative
    Start date: 2002-07-10
    End date: 2006-03-07

Remicade
    Dosage: 19 infusions administered between 10-jul-2002 and 7-mar-2006
    Indication: Crohn's Disease
    Start date: 2002-07-10
    End date: 2006-03-07

Other drugs received by patient: Prednisone TAB; Asacol; Prednisone TAB; Asacol

Possible Remicade side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male, weighing 92.1 kg (202.6 pounds)

Reactions: T-Cell Lymphoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Mercaptopurine
    Start date: 1999-04-01

Mercaptopurine
    Indication: Crohn's Disease
    Start date: 1999-05-01
    End date: 2002-05-12

Mesalamine
    Indication: Crohn's Disease

Remicade

Remicade
    Indication: Crohn's Disease
    Start date: 1999-04-17
    End date: 1999-04-17

Other drugs received by patient: Prednisone TAB

Possible Remicade side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-21

Patient: male, weighing 44.3 kg (97.5 pounds)

Reactions: Hepatosplenic T-Cell Lymphoma

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Remicade
    Start date: 2000-12-01

Remicade
    Indication: Crohn's Disease
    Start date: 2002-04-01

Remicade
    Start date: 2005-10-03

Remicade
    Start date: 2003-02-05

Other drugs received by patient: Imuran; Ciprofloxacin HCL; Mercaptopurine; Pentasa

Possible Remicade side effects in male

Reported by a pharmacist from United States on 2012-08-21

Patient: male, weighing 81.7 kg (179.6 pounds)

Reactions: Neuropathy Peripheral, Lung Neoplasm, Hepatosplenic T-Cell Lymphoma, Nervous System Disorder, Muscle Rupture, Postoperative Abscess

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Start date: 2002-01-01

Mercaptopurine
    Indication: Crohn's Disease
    Start date: 2002-10-01

Mercaptopurine
    Dosage: decreased to 50 mg/day after 6-tg levels were found to be elevated
    Start date: 2004-01-01
    End date: 2006-08-01

Prednisone TAB
    Indication: Crohn's Disease
    Start date: 2003-08-01

Remicade
    Dosage: in 2006, the patient received 3 doses; 24 total doses over total treatment period
    Indication: Crohn's Disease
    Start date: 2002-10-01
    End date: 2006-08-01

Other drugs received by patient: Nexium; Folic Acid; Singulair; Asacol; Calcium; Nystatin; Balsalazide Disodium

Possible Remicade side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male

Reactions: Hepatosplenic T-Cell Lymphoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Remicade
    Dosage: 5mg/kg
    Start date: 2003-03-19
    End date: 2003-03-19

Remicade
    Indication: Crohn's Disease
    Start date: 2003-04-14
    End date: 2003-04-14

Remicade
    Start date: 2003-05-28
    End date: 2003-05-28

Other drugs received by patient: Azathioprine Sodium

Possible Remicade side effects in 52 year old male

Reported by a physician from United States on 2012-08-21

Patient: 52 year old male

Reactions: Myelofibrosis, Polyp, Drug Ineffective, Hepatosplenic T-Cell Lymphoma, Neutropenic Sepsis, Myelodysplastic Syndrome, Myeloproliferative Disorder, Anaphylactoid Reaction, Polycythaemia Vera, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Azathioprine Sodium
    Indication: Crohn's Disease
    Start date: 1989-01-01

Chop NOS
    Indication: Chemotherapy

Corticosteroid Unspecified
    Indication: Crohn's Disease

Dice (Dexamethasone,ifosfamide,cisplatin, Etoposide)
    Indication: Chemotherapy

Humira
    Indication: Crohn's Disease
    Start date: 2005-01-01

Prednisolone
    Indication: Crohn's Disease

Remicade
    Dosage: 3 total infusions
    Indication: Crohn's Disease
    Start date: 2000-01-01

Remicade
    Dosage: 1 infusion
    Start date: 2005-01-01
    End date: 2005-01-01

Tysabri
    Dosage: interval from 1st dose to the event was 7 months; 3 total doses received
    Indication: Crohn's Disease
    Start date: 2008-05-30
    End date: 2008-07-30

Other drugs received by patient: Nortriptyline; Prednisone TAB; Methadone Hydrochloride

Possible Remicade side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male, weighing 81.2 kg (178.6 pounds)

Reactions: Mechanical Ventilation, Renal Failure, Hepatosplenic T-Cell Lymphoma, Sinus Disorder, Pneumothorax

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Administration route: Oral

Mercaptopurine
    Administration route: Oral
    Indication: Crohn's Disease

Mercaptopurine
    Administration route: Oral
    Start date: 2005-02-01

Remicade
    Dosage: started in oct or nov-2005
    Indication: Crohn's Disease
    Start date: 2005-10-01

Remicade
    Dosage: once every 6 to 7 weeks
    End date: 2007-11-20

Other drugs received by patient: Steroids NOS; Allopurinol; Ambien; Wellbutrin; Doxycycline HCL; Protonix; Bentyl; Claritin; Mesalamine; Zoloft

Possible Remicade side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-21

Patient: male, weighing 63.5 kg (139.7 pounds)

Reactions: Night Sweats, Cellulitis, Hepatosplenic T-Cell Lymphoma, Pyrexia, Thirst, Laryngitis, Leukocytoclastic Vasculitis, Epstein-Barr Virus Infection, Fatigue, Sinus Headache, Bacterial Infection, Vision Blurred, Pharyngitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Indication: Crohn's Disease
    Start date: 1999-11-01
    End date: 2001-02-01

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1998-05-01

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1997-12-01

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1997-07-01

Remicade
    Start date: 2000-06-16

Remicade
    Start date: 2000-02-03

Remicade
    Start date: 2003-01-06

Remicade
    Start date: 2002-11-15

Remicade
    Start date: 2002-09-27

Remicade
    Start date: 1999-12-03

Remicade
    Start date: 1999-09-01

Remicade
    Start date: 2002-06-21

Remicade
    Indication: Crohn's Disease
    Start date: 2000-08-17

Remicade
    Start date: 2000-11-05

Remicade
    Start date: 2002-08-09

Remicade
    Start date: 2002-02-22

Remicade
    Start date: 2002-02-11

Other drugs received by patient: Prilosec; Azathioprine Sodium; Imuran; Prednisone TAB; Corticosteroids; Fosamax

Possible Remicade side effects in 15 year old male

Reported by a physician from United States on 2012-08-21

Patient: 15 year old male, weighing 38.3 kg (84.3 pounds)

Reactions: Respiratory Failure, Hepatosplenic T-Cell Lymphoma, Disseminated Intravascular Coagulation, Lactic Acidosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade

Remicade

Remicade

Remicade

Remicade
    End date: 2005-06-15

Remicade
    Dosage: patient received 13 treatments.
    Start date: 2004-02-11

Remicade

Remicade

Remicade

Remicade
    Dosage: patient received 13 treatments.
    Indication: Crohn's Disease
    Start date: 2004-02-01

Remicade

Remicade

Remicade

Other drugs received by patient: Prednisone TAB; Human Growth Hormone; Imuran; Imuran; Imuran; Calcium + Vitamin D; Imuran; Imuran; Feosol; Asacol; Mercaptopurine; 5-Aminosalicylic Acid; Imuran; Imuran; Forvia; Zantac

Possible Remicade side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female

Reactions: B-Cell Lymphoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Remicade

Other drugs received by patient: Mercaptopurine

Possible Remicade side effects in male

Reported by a physician from Australia on 2012-08-21

Patient: male, weighing 120.0 kg (264.0 pounds)

Reactions: Hepatosplenic T-Cell Lymphoma, Staphylococcal Sepsis

Adverse event resulted in: death, life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Azathioprine Sodium
    Dosage: 2-2.5 mg/kg
    Start date: 1993-01-01
    End date: 1994-01-01

Azathioprine Sodium
    Indication: Crohn's Disease
    Start date: 1999-08-01
    End date: 2006-01-01

Prednisolone
    Dosage: varying doses
    Indication: Crohn's Disease
    Start date: 1993-01-01

Remicade
    Dosage: 3 infusions
    Indication: Crohn's Disease
    Start date: 1999-11-01
    End date: 2000-01-01

Possible Remicade side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male

Reactions: Drug Ineffective, Hepatosplenic T-Cell Lymphoma, Anaemia, Sepsis, Thrombocytopenia, Leukopenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Azathioprine Sodium
    Administration route: Oral
    Indication: Crohn's Disease
    Start date: 1996-01-01
    End date: 2004-05-01

Azathioprine Sodium
    Dosage: variable and lower doses
    Administration route: Oral
    Start date: 2004-01-01
    End date: 2007-04-01

Humira
    Indication: Crohn's Disease
    Start date: 2007-01-01
    End date: 2007-11-01

Humira
    Start date: 2005-05-04
    End date: 2005-11-10

Remicade
    Indication: Crohn's Disease
    Start date: 2004-04-15
    End date: 2004-06-10

Possible Remicade side effects in male

Reported by a pharmacist from United States on 2012-08-21

Patient: male, weighing 74.0 kg (162.8 pounds)

Reactions: Hepatosplenic T-Cell Lymphoma, Pancytopenia, Pyrexia, Convulsion, Mucosal Inflammation, Tumour Lysis Syndrome, Small Intestinal Ulcer Haemorrhage, Haemorrhagic Diathesis, Neutropenia

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Imuran
    Administration route: Oral
    Indication: Crohn's Disease
    Start date: 1997-03-25
    End date: 1997-12-01

Imuran
    Administration route: Oral
    Start date: 1999-06-14
    End date: 2002-05-22

Imuran
    Administration route: Oral
    Start date: 1997-12-01
    End date: 1999-06-13

Imuran
    Administration route: Oral
    Start date: 2001-10-25

Remicade
    Start date: 2001-12-10

Remicade
    Start date: 2001-10-24
    End date: 2001-10-24

Remicade
    Start date: 2002-05-22
    End date: 2002-05-22

Remicade
    Start date: 2001-11-08

Remicade
    Indication: Crohn's Disease
    Start date: 2002-02-25
    End date: 2002-02-25

Other drugs received by patient: Prednisone TAB; Prednisone TAB; Probiotica; Mercaptopurine; Multi-Vitamin; Iron; Budesonide; Calcium; Entocort EC; Vitamin E; Entocort EC; Macrobid

Possible Remicade side effects in male

Reported by a physician from United Kingdom on 2012-08-21

Patient: male

Reactions: Pelvic Pain, Pyrexia, Anal Fistula, C-Reactive Protein Increased, Splenomegaly, Rectal Abscess, Lethargy, Hepatosplenic T-Cell Lymphoma, Crohn's Disease, Sepsis, Platelet Count Decreased, Diabetic Ketoacidosis, Neutropenia, Rectal Discharge, Leukopenia, Influenza Like Illness

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Azathioprine Sodium
    Dosage: 2.5 mg/kg
    Indication: Crohn's Disease

Azathioprine Sodium
    Start date: 2002-01-01
    End date: 2006-09-01

Azathioprine Sodium
    Start date: 2001-06-01

Mercaptopurine
    Indication: Crohn's Disease

Prednisolone
    Indication: Product Used FOR Unknown Indication

Remicade
    Indication: Crohn's Disease
    End date: 2005-09-29

Remicade
    Dosage: stopped in february - march (3rd infusion)
    End date: 2006-02-01

Other drugs received by patient: Metronidazole; Vitamin B-12

Possible Remicade side effects in male

Reported by a pharmacist from United States on 2012-08-21

Patient: male

Reactions: Aqueductal Stenosis, Antiphospholipid Syndrome, Graft Versus Host Disease, Hepatosplenic T-Cell Lymphoma, Nuclear Magnetic Resonance Imaging Brain Abnormal, Pulmonary Embolism, Hydrocephalus, Hypertension

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Imuran
    Indication: Colitis
    Start date: 2002-11-15

Imuran
    Start date: 2001-12-01
    End date: 2002-11-14

Lovenox
    Indication: Product Used FOR Unknown Indication

Remicade
    Dosage: single infusion
    Indication: Colitis Ulcerative
    Start date: 2001-12-22
    End date: 2001-12-22

Other drugs received by patient: Asacol; Heparin; Heparin; Steroids

Possible Remicade side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male

Reactions: Multi-Organ Failure, Hepatosplenic T-Cell Lymphoma, Staphylococcal Abscess

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Indication: Crohn's Disease

Remicade
    Dosage: date also reported as 5-may-2005
    Start date: 2005-04-01

Remicade
    Dosage: second dose
    Indication: Crohn's Disease
    Start date: 2005-03-21

Remicade
    Start date: 2000-01-01

Other drugs received by patient: Prednisone TAB; Mesalamine

Possible Remicade side effects in 23 year old male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-21

Patient: 23 year old male

Reactions: Epstein-Barr Virus Infection, Histiocytosis Haematophagic, Hepatosplenic T-Cell Lymphoma, Septic Shock

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade

Other drugs received by patient: Mercaptopurine; Azathioprine Sodium

Possible Remicade side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female, weighing 53.0 kg (116.6 pounds)

Reactions: Hepatosplenic T-Cell Lymphoma, Neutropenic Sepsis

Adverse event resulted in: death

Drug(s) suspected as cause:
Mercaptopurine

Mercaptopurine
    Indication: Crohn's Disease

Mesalamine
    Indication: Crohn's Disease

Remicade
    Dosage: summer 2003
    Indication: Crohn's Disease
    Start date: 2001-01-15
    End date: 2003-08-15

Other drugs received by patient: Metronidazole; Hydrocortisone; Prednisone TAB

Possible Remicade side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male, weighing 115.7 kg (254.5 pounds)

Reactions: Gastrointestinal Haemorrhage, Cholecystitis Acute, T-Cell Lymphoma, Disseminated Intravascular Coagulation, Pancytopenia, Atrial Fibrillation, Multi-Organ Failure, Sepsis, Acute Respiratory Distress Syndrome

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Indication: T-Cell Lymphoma
    Start date: 2006-09-10

Cyclophosphamide
    Indication: T-Cell Lymphoma
    Start date: 2006-01-01

Prednisone TAB
    Indication: T-Cell Lymphoma
    Start date: 2006-01-01

Remicade
    Dosage: 3 dose induction followed by maint. q 8 weeks, 300 mg on 29-jun-2006, total 27 infusions
    Indication: Rheumatoid Arthritis
    Start date: 2001-10-01
    End date: 2006-06-29

Vincristine
    Indication: T-Cell Lymphoma
    Start date: 2006-09-10

Other drugs received by patient: Azulfadine; Lisinopril

Possible Remicade side effects in female

Reported by a physician from Denmark on 2012-08-21

Patient: female, weighing 55.0 kg (121.0 pounds)

Reactions: Intestinal T-Cell Lymphoma

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade
    Dosage: total of 9 infusions received
    Indication: Crohn's Disease
    Start date: 2007-01-01

Remicade
    Dosage: total of 3 infusions received
    Start date: 2008-11-28
    End date: 2009-01-08

Other drugs received by patient: Vibeden; Calcium with Vitamin D; Prednisolone; Pantoprazole Sodium; Pinex

Possible Remicade side effects in male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-21

Patient: male

Reactions: Hepatosplenic T-Cell Lymphoma

Adverse event resulted in: death

Drug(s) suspected as cause:
Remicade

Other drugs received by patient: Pulse Steroids; Asacol; Azathioprine Sodium

Possible Remicade side effects in 46 year old male

Reported by a physician from United Kingdom on 2012-08-20

Patient: 46 year old male

Reactions: Bronchopneumonia, Septic Shock, Leukopenia, Immunosuppression

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade
    Dosage: 4-5 infusions
    Indication: Crohn's Disease

Remicade
    Dosage: 4th infusion
    Start date: 2011-01-11

Zometa
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-01-17

Other drugs received by patient: TPN; Prednisolone; Azathioprine Sodium

Possible Remicade side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20

Patient: female, weighing 59.9 kg (131.7 pounds)

Reactions: Hypovolaemic Shock, Urinary Tract Infection, Coagulopathy, Hypotension, Hepatic Enzyme Increased, Renal Failure, Sepsis Syndrome, Neuropathy Peripheral, Electrolyte Imbalance, Thrombocytopenia, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade
    Start date: 2012-03-28

Remicade
    Start date: 2012-04-26

Remicade
    Dosage: 4 vials
    Indication: Crohn's Disease
    Start date: 2012-03-14

Other drugs received by patient: Neurontin; Atarax; Protonix; Prednisone TAB; Morphine Sulfate; Prednisone TAB; Tylenol; Multivitamin; MS Contin; Rocaltrol; Vitamin D; Folic Acid; MAG-TAB; Bicarbonate; Norvasc; Celexa; Zofran; Coumadin

Possible Remicade side effects in male

Reported by a physician from United States on 2012-08-20

Patient: male

Reactions: Meningitis Listeria

Adverse event resulted in: death

Drug(s) suspected as cause:
Remicade
    Indication: Rheumatoid Arthritis

Remicade
    Start date: 2012-07-16

Other drugs received by patient: Methotrexate

Possible Remicade side effects in female

Reported by a physician from Japan on 2012-08-20

Patient: female, weighing 47.7 kg (104.9 pounds)

Reactions: Cardio-Respiratory Arrest, Metabolic Acidosis, Hepatic Function Abnormal, Arthralgia, Disseminated Intravascular Coagulation, Platelet Count Decreased, Pyrexia, Device Related Infection, Septic Shock

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Prednisolone
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Remicade
    Indication: Rheumatoid Arthritis
    Start date: 2011-12-06

Remicade
    Start date: 2010-09-03

Remicade
    Dosage: 20th dose
    Start date: 2012-06-01

Remicade
    Start date: 2009-08-21

Other drugs received by patient: Folic Acid; Edirol; Lansoprazole; Cefazolin Sodium; Warfarin Sodium

Possible Remicade side effects in male

Reported by a physician from United States on 2012-08-17

Patient: male, weighing 109.3 kg (240.5 pounds)

Reactions: Pneumonia, Hepatosplenic T-Cell Lymphoma

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Imuran
    Administration route: Oral
    Start date: 2004-03-11
    End date: 2004-07-29

Imuran
    Administration route: Oral
    Indication: Crohn's Disease
    Start date: 2004-07-29
    End date: 2011-05-25

Remicade
    Indication: Crohn's Disease
    Start date: 2006-11-22

Remicade

Remicade
    End date: 2011-09-09

Other drugs received by patient: Imodium A-D; Imodium A-D; Prednisone TAB; Sulfamethoxazole and Trimethoprim; Folic Acid; Nplate; Multi-Vitamins

Possible Remicade side effects in 73 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-17

Patient: 73 year old male

Reactions: Multi-Organ Failure, Disseminated Tuberculosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade