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Pyrazinamide (Pyrazinamide) - Drug Rash With Eosinophilia and Systemic Symptoms - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Rash With Eosinophilia and Systemic Symptoms (10)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Pyrazinamide where reactions include drug rash with eosinophilia and systemic symptoms. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Pyrazinamide side effects in 23 year old male

Reported by a health professional (non-physician/pharmacist) from Thailand on 2012-08-01

Patient: 23 year old male

Reactions: Drug Rash With Eosinophilia and Systemic Symptoms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Isoniazid
    Dosage: unk
    Indication: Pulmonary Tuberculosis

Ethambutol Hydrochloride
    Dosage: unk
    Indication: Pulmonary Tuberculosis

Rifampicin
    Dosage: unk
    Indication: Pulmonary Tuberculosis

Pyrazinamide
    Dosage: unk
    Indication: Pulmonary Tuberculosis



Possible Pyrazinamide side effects in 56 year old male

Reported by a health professional (non-physician/pharmacist) from Thailand on 2012-08-01

Patient: 56 year old male

Reactions: Drug Rash With Eosinophilia and Systemic Symptoms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Pyrazinamide
    Dosage: unk
    Indication: Pulmonary Tuberculosis

Rifampicin
    Dosage: unk
    Indication: Pulmonary Tuberculosis

Isoniazid
    Dosage: unk
    Indication: Pulmonary Tuberculosis

Ethambutol Hydrochloride
    Dosage: unk
    Indication: Pulmonary Tuberculosis



Possible Pyrazinamide side effects in 23 year old male

Reported by a health professional (non-physician/pharmacist) from Thailand on 2012-07-12

Patient: 23 year old male

Reactions: Lymphopenia, Pyrexia, Drug Rash With Eosinophilia and Systemic Symptoms, Rash Maculo-Papular, Hepatitis, Eosinophilia

Drug(s) suspected as cause:
Rifampicin

Ethambutol Hydrochloride

Pyrazinamide

Isoniazid



Possible Pyrazinamide side effects in 56 year old male

Reported by a health professional (non-physician/pharmacist) from Thailand on 2012-07-12

Patient: 56 year old male

Reactions: Lymphopenia, Pyrexia, Drug Rash With Eosinophilia and Systemic Symptoms, Hepatitis, Rash Maculo-Papular, Eosinophilia, Pneumonitis

Drug(s) suspected as cause:
Ethambutol Hydrochloride

Isoniazid

Pyrazinamide

Rifampicin



Possible Pyrazinamide side effects in 56 year old male

Reported by a health professional (non-physician/pharmacist) from Thailand on 2012-05-10

Patient: 56 year old male

Reactions: Lymphopenia, Pyrexia, Drug Rash With Eosinophilia and Systemic Symptoms, Hepatitis, Rash Maculo-Papular, Pneumonitis, Eosinophilia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Isoniazid
    Indication: Pulmonary Tuberculosis

Ethambutol Hydrochloride
    Indication: Pulmonary Tuberculosis

Pyrazinamide
    Indication: Pulmonary Tuberculosis

Rifampicin
    Indication: Pulmonary Tuberculosis



Possible Pyrazinamide side effects in 23 year old male

Reported by a health professional (non-physician/pharmacist) from Thailand on 2012-05-10

Patient: 23 year old male

Reactions: Lymphopenia, Pyrexia, Rash Maculo-Papular, Hepatitis, Drug Rash With Eosinophilia and Systemic Symptoms, Eosinophilia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Rifampicin
    Indication: Pulmonary Tuberculosis

Pyrazinamide
    Indication: Pulmonary Tuberculosis

Isoniazid
    Indication: Pulmonary Tuberculosis

Ethambutol Hydrochloride
    Indication: Pulmonary Tuberculosis



Possible Pyrazinamide side effects in 63 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-04-30

Patient: 63 year old male

Reactions: Hepatic Function Abnormal, Pyrexia, Drug Rash With Eosinophilia and Systemic Symptoms, Erythema

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rifampicin
    Administration route: Oral
    Start date: 2011-03-31

Isoniazid
    Administration route: Oral
    Indication: Tuberculous Pleurisy
    Start date: 2011-03-31

Ethambutol Hydrochloride
    Administration route: Oral
    Indication: Tuberculous Pleurisy
    Start date: 2011-03-31

Pyrazinamide
    Indication: Tuberculous Pleurisy
    Start date: 2011-03-31



Possible Pyrazinamide side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-12

Patient: 52 year old male

Reactions: Lymphadenopathy, Pyrexia, Drug Rash With Eosinophilia and Systemic Symptoms, Erythema, Liver Disorder, Eosinophilia, Lymphocyte Morphology Abnormal, Leukocytosis

Drug(s) suspected as cause:
Pyrazinamide
    Indication: Tuberculous Pleurisy

Ethambutol Hydrochloride
    Indication: Tuberculous Pleurisy

Isoniazid
    Indication: Tuberculous Pleurisy

Rifampicin
    Indication: Tuberculous Pleurisy



Possible Pyrazinamide side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-06

Patient: 52 year old male

Reactions: Lymphadenopathy, Pyrexia, Erythema, Drug Rash With Eosinophilia and Systemic Symptoms, Eosinophilia, Liver Disorder, Lymphocyte Morphology Abnormal, Leukocytosis

Drug(s) suspected as cause:
Rifampicin
    Indication: Tuberculous Pleurisy

Pyrazinamide
    Indication: Tuberculous Pleurisy

Isoniazid
    Indication: Tuberculous Pleurisy

Ethambutol Hydrochloride
    Indication: Tuberculous Pleurisy



Possible Pyrazinamide side effects in 61 year old female

Reported by a physician from Korea, Republic of on 2011-11-03

Patient: 61 year old female, weighing 43.0 kg (94.6 pounds)

Reactions: Hepatotoxicity, Drug Rash With Eosinophilia and Systemic Symptoms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Levofloxacin
    Indication: Tuberculosis
    Start date: 2011-01-20
    End date: 2011-03-22

Isoniazid
    Start date: 2011-01-20

Cycloserine
    Start date: 2011-04-11
    End date: 2011-04-12

Levofloxacin
    Start date: 2011-04-11
    End date: 2011-04-12

Rifampin
    Indication: Tuberculosis
    Start date: 2011-01-20
    End date: 2011-03-22

Isoniazid
    Indication: Tuberculosis
    Start date: 2011-04-28

Isoniazid
    Start date: 2011-04-18
    End date: 2011-04-19

Cycloserine
    Indication: Tuberculosis
    Start date: 2011-05-13

Streptomycin
    Indication: Tuberculosis
    Start date: 2011-04-11
    End date: 2011-04-12

Pyridoxine HCL
    Indication: Tuberculosis
    Start date: 2011-03-29

Ethambutol Hydrochloride
    Start date: 2011-01-20
    End date: 2011-03-22

Streptomycin
    Start date: 2011-01-20
    End date: 2011-03-22

Streptomycin
    Start date: 2011-05-09
    End date: 2011-05-09

Ethambutol Hydrochloride
    Indication: Tuberculosis
    Start date: 2011-04-11
    End date: 2011-04-12

Pyrazinamide
    Indication: Tuberculosis
    Start date: 2011-01-20

Amikacin
    Indication: Tuberculosis

Other drugs received by patient: Concor; Prothionamide; Omeprazole

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