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Purinethol (Mercaptopurine) - Cholestasis - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Cholestasis (3)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Purinethol (Mercaptopurine) where reactions include cholestasis. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Purinethol side effects in 42 year old male

Reported by a consumer/non-health professional from Germany on 2012-02-15

Patient: 42 year old male, weighing 87.0 kg (191.4 pounds)

Reactions: Hyperbilirubinaemia, Cholestasis

Drug(s) suspected as cause:
Vincristine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-12-26

Dasatinib
    Dosage: interrupted:12jan12 to 17jan12.
    Indication: Acute Lymphocytic Leukaemia

Cyclophosphamide
    Dosage: also taken on 25jan12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-01

Purinethol
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-07
    End date: 2012-01-09

Pegaspargase
    Dosage: 1df= 4000u
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-12-26

Methotrexate
    Dosage: also on 10jan12,18jan12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-03



Possible Purinethol side effects in 42 year old male

Reported by a consumer/non-health professional from Germany on 2012-02-14

Patient: 42 year old male, weighing 87.0 kg (191.4 pounds)

Reactions: Hyperbilirubinaemia, Cholestasis

Drug(s) suspected as cause:
Vincristine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-12-26

Cyclophosphamide
    Dosage: also taken on 25jan12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-01

Purinethol
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-07
    End date: 2012-01-09

Dasatinib
    Dosage: interrupted:12jan12 to 17jan12.
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: also on 10jan12,18jan12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-03

Pegaspargase
    Dosage: 1df= 4000u
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-12-26



Possible Purinethol side effects in 42 year old male

Reported by a consumer/non-health professional from Germany on 2012-01-20

Patient: 42 year old male, weighing 87.0 kg (191.4 pounds)

Reactions: Hyperbilirubinaemia, Cholestasis

Drug(s) suspected as cause:
Vincristine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-12-26

Cyclophosphamide
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-01

Purinethol
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-07
    End date: 2012-01-09

Methotrexate
    Dosage: also on 10-jan-2012
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-03

Pegaspargase
    Dosage: 1df= 4000u
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2011-12-26

Dasatinib
    Dosage: interrupted:12jan2012.
    Indication: Acute Lymphocytic Leukaemia

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