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Piperacillin and Tazobactam (Piperacillin / Tazobactam) - Life Threatening Events - Suspected Cause - Side Effect Reports

 
 



Index of reports > Life Threatening Events (66)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Piperacillin and Tazobactam (Piperacillin / Tazobactam) life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 66   Next >>

Possible Piperacillin and Tazobactam side effects in 71 year old male

Reported by a pharmacist from United States on 2012-08-21

Patient: 71 year old male

Reactions: Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Piperacillin and Tazobactam
    Indication: Urinary Tract Infection
    Start date: 2012-07-13
    End date: 2012-07-19

Piperacillin and Tazobactam
    Indication: Sepsis
    Start date: 2012-07-13
    End date: 2012-07-19



Possible Piperacillin and Tazobactam side effects in 48 year old female

Reported by a physician from United Kingdom on 2012-08-17

Patient: 48 year old female, weighing 98.0 kg (215.6 pounds)

Reactions: Type IV Hypersensitivity Reaction, Petechiae, Withdrawal Syndrome, Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Piperacillin and Tazobactam

Other drugs received by patient: Dalteparin Sodium; Folic Acid; Ferrous Sulfate TAB; Acetaminophen; Cyclizine; Codeine Sulfate



Possible Piperacillin and Tazobactam side effects in 70 year old male

Reported by a physician from China on 2012-08-16

Patient: 70 year old male

Reactions: Atrioventricular Block Complete

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam
    Indication: Infection Prophylaxis

Piperacillin and Tazobactam
    Dosage: unk
    Indication: Diabetic Foot Infection
    Start date: 2012-04-12
    End date: 2012-04-16

Other drugs received by patient: Phosphatidyl Choline; Tinidazole; Diammonium Glycyrrhizinate; Alprostadil; Amlodipine; Valsartan; Insulin Glargine; Ginkgo Biloba; Acetylsalicylic Acid; Insulin Aspart



Possible Piperacillin and Tazobactam side effects in male

Reported by a pharmacist from United States on 2012-08-14

Patient: male, weighing 60.8 kg (133.8 pounds)

Reactions: Tubulointerstitial Nephritis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam



Possible Piperacillin and Tazobactam side effects in 65 year old male

Reported by a pharmacist from United States on 2012-08-09

Patient: 65 year old male, weighing 83.6 kg (183.9 pounds)

Reactions: Anaphylactic Reaction

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Piperacillin and Tazobactam
    Dosage: 3.75 gm once iv
    Start date: 2011-10-28
    End date: 2011-10-28

Cefazolin
    Dosage: 2 gm once iv
    Start date: 2011-10-28
    End date: 2011-10-28



Possible Piperacillin and Tazobactam side effects in 58 year old male

Reported by a pharmacist from United States on 2012-08-09

Patient: 58 year old male, weighing 95.5 kg (210.1 pounds)

Reactions: Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Piperacillin and Tazobactam
    Dosage: 3.375 gm qid iv
    Start date: 2011-08-30
    End date: 2011-09-07

Vancomycin
    Dosage: 1500 mg bid iv
    Start date: 2011-08-30
    End date: 2011-09-04



Possible Piperacillin and Tazobactam side effects in 29 year old male

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-02

Patient: 29 year old male

Reactions: Hyperoxaluria, Renal Tubular Necrosis, Crystal Nephropathy, Renal Failure Acute

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Trimethoprim + Sulfamethoxazole

Voriconazole

Moxifloxacin

Ganciclovir

Amikacin

Piperacillin and Tazobactam

Vancomycin

Other drugs received by patient: Mycophenolate Mofetil; Creon [amylase,lipase,pancreatin,protease]; Basiliximab; Methylprednisolone; Tacrolimus; Corticosteroids; Insulin



Possible Piperacillin and Tazobactam side effects in 79 year old male

Reported by a pharmacist from United States on 2012-07-30

Patient: 79 year old male, weighing 79.1 kg (174.0 pounds)

Reactions: Cardio-Respiratory Arrest, Anaphylactic Reaction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam
    Dosage: 3.375 gm qid iv
    Start date: 2012-05-10
    End date: 2012-05-10

Vancomycin
    Dosage: 1 gm every day iv
    Indication: Cellulitis
    Start date: 2012-05-10
    End date: 2012-05-10



Possible Piperacillin and Tazobactam side effects in 60 year old male

Reported by a pharmacist from United States on 2012-07-30

Patient: 60 year old male, weighing 138.6 kg (304.9 pounds)

Reactions: Dyspnoea, Hypotension, Tachycardia, Anaphylactic Reaction, Chills, Respiratory Depression

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Vancomycin
    Dosage: 2500mg other iv
    Indication: Upper Respiratory Tract Infection
    Start date: 2012-06-16
    End date: 2012-06-16

Piperacillin and Tazobactam
    Dosage: 2.25gm other iv
    Indication: Pneumonia
    Start date: 2012-06-16
    End date: 2012-06-18



Possible Piperacillin and Tazobactam side effects in 48 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-30

Patient: 48 year old female, weighing 98.0 kg (215.6 pounds)

Reactions: Petechiae, Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Piperacillin and Tazobactam

Other drugs received by patient: Folic Acid; Cyclizine (Cyclizine); Codein (Codeine Phosphate); Dalteparin Sodium; Ferrous Sulfate TAB; Acetaminophen



Possible Piperacillin and Tazobactam side effects in 82 year old male

Reported by a physician from France on 2012-07-20

Patient: 82 year old male

Reactions: Lymphocyte Count Increased, Hyperthermia, Neutropenia, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Acetaminophen
    Dosage: 1 dosage form; iv
    Start date: 2012-06-05
    End date: 2012-06-18

Piperacillin and Tazobactam
    Start date: 2012-06-05
    End date: 2012-06-18

Augmentin '125'
    Start date: 2012-06-14
    End date: 2012-06-18

Other drugs received by patient: Aspirin; Esomeprazole; Molsidomine; Nitroglycerin; Lovenox; Irbesartan; Atorvastatin; Sectral



Possible Piperacillin and Tazobactam side effects in 82 year old male

Reported by a physician from France on 2012-07-13

Patient: 82 year old male

Reactions: Hyperthermia, Neutropenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Acetaminophen
    Dosage: 1 dosage form;iv
    Start date: 2012-06-05
    End date: 2012-06-18

Piperacillin and Tazobactam
    Start date: 2012-06-05
    End date: 2012-06-18

Augmentin
    Start date: 2012-06-14
    End date: 2012-06-18

Other drugs received by patient: Lovenox; Molsidomine; Atorvastatin; Aspirin; Irbesartan; Esomeprazole; Nitroglycerin



Possible Piperacillin and Tazobactam side effects in 62 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-06

Patient: 62 year old male

Reactions: LIP Swelling, Electrocardiogram ST Segment Depression, Hypotension, Myocardial Strain, Swollen Tongue, Hypertension, Paraesthesia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam

Other drugs received by patient: Bisoprolol Fumarate; Atorvastatin; Dalteparin Sodium; Acetaminophen; Ramipril; CO-Amoxiclav (Spektramox / 02043401 / ); Omeprazole; Aspirin; Prasugrel (Prasugrel); Codeine Phosphate (Codeine Phosphate)



Possible Piperacillin and Tazobactam side effects in 70 year old male

Reported by a physician from China on 2012-07-05

Patient: 70 year old male

Reactions: Atrioventricular Block Complete

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam
    Indication: Infection Prophylaxis

Piperacillin and Tazobactam
    Indication: Diabetic Foot Infection

Other drugs received by patient: Amlodipine; Acetylsalicylic Acid; Phosphatidyl Choline; Insulin Aspart; Insulin Glargine; Ginkgo Biloba; Tinidazole; Diammonium Glycyrrhizinate; Alprostadil; Valsartan



Possible Piperacillin and Tazobactam side effects in 76 year old male

Reported by a pharmacist from United States on 2012-06-13

Patient: 76 year old male

Reactions: Renal Injury, Dialysis, Renal Failure Acute

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam



Possible Piperacillin and Tazobactam side effects in 64 year old male

Reported by a pharmacist from United States on 2012-06-08

Patient: 64 year old male, weighing 87.9 kg (193.4 pounds)

Reactions: Peritoneal Fluid Analysis Abnormal, Tongue Blistering, Toxic Epidermal Necrolysis, Orthostatic Hypotension, Condition Aggravated, Haemorrhagic Anaemia, Alcoholic Liver Disease, Chronic Obstructive Pulmonary Disease, Haemorrhoidal Haemorrhage, Diverticulum, Large Intestinal Ulcer Haemorrhage, Diarrhoea, Leukocytosis, Blister, Stevens-Johnson Syndrome

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Vancomycin
    Dosage: 750 mg bid iv
    Indication: Peritoneal Fluid Analysis Abnormal
    Start date: 2012-05-18
    End date: 2012-05-20

Piperacillin and Tazobactam
    Dosage: 3.75 mg qid iv
    Indication: Peritoneal Fluid Analysis Abnormal
    Start date: 2012-05-18
    End date: 2012-05-20



Possible Piperacillin and Tazobactam side effects in 70 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-29

Patient: 70 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Potentiating Drug Interaction, Tachycardia, Pain, Pyrexia, C-Reactive Protein Increased, Liver Function Test Abnormal, Blister, Stevens-Johnson Syndrome, Renal Failure Acute, White Blood Cell Count Decreased, Pancytopenia, Haemoglobin Decreased, Mucosal Inflammation, Mucosal Ulceration, Sepsis, Rash Erythematous, Platelet Count Decreased, Inflammation

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Ciprofloxacin HCL
    Dosage: 1 df, bid, indication: infected hip prosthesis
    Administration route: Oral
    Indication: Infection
    Start date: 2011-03-29
    End date: 2012-04-05

Methotrexate
    Dosage: 20 mg, 1/week
    Administration route: Oral
    Indication: Psoriatic Arthropathy
    End date: 2012-04-07

Piperacillin and Tazobactam
    Dosage: 4.5 g, bid, indication: infected hip prosthesis
    Indication: Infection
    Start date: 2012-04-05

Other drugs received by patient: Allopurinol; Teicoplanin; Rifampicin; Gentamicin; Ciprofloxacin



Possible Piperacillin and Tazobactam side effects in 70 year old female

Reported by a physician on 2012-05-25

Patient: 70 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Hepatic Function Abnormal, Tachycardia, Pancytopenia, Drug Interaction, General Physical Health Deterioration, Haemodialysis, Arthritis Bacterial, Stevens-Johnson Syndrome, Renal Failure Acute

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Methotrexate
    Dosage: 20 mg, 1 in 1 wk, oral
    Administration route: Oral
    Indication: Psoriatic Arthropathy
    End date: 2012-04-07

Ciprofloxacin
    Dosage: 2 dosage forms (1 dosage forms, 2 in 1 d), oral
    Administration route: Oral
    Indication: Infection
    Start date: 2011-03-29
    End date: 2012-04-05

Piperacillin and Tazobactam
    Dosage: 9 gm (4.5 gm, 2 in 1 d), intravenous
    Indication: Infection
    Start date: 2012-04-05

Other drugs received by patient: Rifampicin; Ciprofloxacin (Ciprogloxacin); Gentamicin (Gentamincin); Allopurinol; Teicoplanin (Teicoplanin)



Possible Piperacillin and Tazobactam side effects in 70 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-18

Patient: 70 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: White Blood Cell Count Decreased, Pain, Tachycardia, Pancytopenia, Pyrexia, Haemoglobin Decreased, Sepsis, Liver Function Test Abnormal, Renal Failure Acute, Stevens-Johnson Syndrome, Inflammation

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Methotrexate
    Dosage: 20 mg, 1 in 1 wk, oral
    Administration route: Oral
    Indication: Psoriatic Arthropathy
    End date: 2012-04-07

Piperacillin and Tazobactam
    Dosage: 4.5 mg, 2 in 1 d, intravenous (not otherwise specified)
    Indication: Infection
    Start date: 2012-04-05

Ciprofloxacin
    Dosage: 1 dosage forms, 2 in 1 d, oral, 2 gm
    Administration route: Oral
    Indication: Infection
    Start date: 2011-03-29
    End date: 2012-04-05

Ciprofloxacin
    Dosage: 1 dosage forms, 2 in 1 d, oral, 2 gm
    Administration route: Oral
    Indication: Infection
    Start date: 2009-06-01

Ciprofloxacin
    Dosage: 1 dosage forms, 2 in 1 d, oral, 2 gm
    Administration route: Oral
    Indication: Infection

Other drugs received by patient: Gentamicin; Rifampicin; Allopurinol; Teicoplanin (Teicoplanin)



Possible Piperacillin and Tazobactam side effects in 70 year old female

Reported by a physician from United Kingdom on 2012-05-17

Patient: 70 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Tachycardia, Potentiating Drug Interaction, Pain, Pyrexia, C-Reactive Protein Increased, Liver Function Test Abnormal, Stevens-Johnson Syndrome, Blister, Renal Failure Acute, White Blood Cell Count Decreased, Pancytopenia, Haemoglobin Decreased, Mucosal Inflammation, Mucosal Ulceration, Rash Erythematous, Sepsis, Platelet Count Decreased, Inflammation

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam

Other drugs received by patient possibly interacting with the suspect drug:
Ciprofloxacin HCL
    Administration route: Oral
    Indication: Infection
    Start date: 2011-03-29
    End date: 2012-04-05

Methotrexate Sodium
    Dosage: 20 mg, weekly
    Administration route: Oral
    Indication: Psoriatic Arthropathy
    End date: 2012-04-07

Other drugs received by patient: Gentamicin; Rifampicin; Ciprofloxacin; Allopurinol; Teicoplanin



Possible Piperacillin and Tazobactam side effects in 70 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-17

Patient: 70 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Potentiating Drug Interaction, Tachycardia, Pain, Pyrexia, C-Reactive Protein Increased, Liver Function Test Abnormal, Stevens-Johnson Syndrome, Renal Failure Acute, Blister, White Blood Cell Count Decreased, Pancytopenia, Haemoglobin Decreased, Mucosal Ulceration, Rash Erythematous, Sepsis, Platelet Count Decreased, Inflammation

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam

Other drugs received by patient possibly interacting with the suspect drug:
Methotrexate
    Dosage: 20 mg, ow
    Administration route: Oral
    Indication: Psoriatic Arthropathy
    End date: 2012-04-07

Ciprofloxacin HCL
    Dosage: 1 df, bid
    Administration route: Oral
    Indication: Infection
    Start date: 2012-03-29
    End date: 2012-04-05

Other drugs received by patient: Ciprofloxacin; Gentamicin; Allopurinol; Teicoplanin; Rifampicin



Possible Piperacillin and Tazobactam side effects in 70 year old male

Reported by a physician from China on 2012-05-15

Patient: 70 year old male

Reactions: Atrioventricular Block Complete

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam
    Indication: Diabetic Foot Infection

Piperacillin and Tazobactam
    Indication: Infection Prophylaxis

Other drugs received by patient: Ginkgo Biloba; Acetylsalicylic Acid; Amlodipine; Insulin Glargine; Alprostadil; Insulin Aspart; Valsartan; Tinidazole; Diammonium Glycyrrhizinate; Phosphatidyl Choline



Possible Piperacillin and Tazobactam side effects in 94 year old male

Reported by a health professional (non-physician/pharmacist) on 2012-04-25

Patient: 94 year old male

Reactions: Platelet Count Decreased, Neutropenia, Leukopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Piperacillin and Tazobactam
    Dosage: 13.5 gm (4.5 gm, 1 in 8 hr), intravenous
    Indication: Lower Respiratory Tract Infection
    Start date: 2012-03-20
    End date: 2012-03-26

Piperacillin and Tazobactam
    Dosage: 13.5 gm (4.5 gm, 1 in 8 hr), intravenous
    Indication: Sepsis
    Start date: 2012-03-20
    End date: 2012-03-26

Other drugs received by patient: Clarithromycin; Lactulose; Enoxaparin Sodium; Phenytoin; Benzylpenicillin (Benzylpenicillin); Hydrocortone; Ipratropium (Iprotropium); Fludrocortisone Acetate; Gentamicin; Omeprazole; Acetaminophen; Phosphate Sandoz (Phosphate Sandoz); Albuterol Sulfate; Calcchew D3 (Lekovit CA); Furosemide; Lansoprazole; Loperamide



Possible Piperacillin and Tazobactam side effects in 94 year old male

Reported by a pharmacist from United Kingdom on 2012-04-17

Patient: 94 year old male

Reactions: Platelet Count Decreased, Neutropenia, Leukopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Piperacillin and Tazobactam

Other drugs received by patient: Calcium Carbonate; Furosemide; Paracetamol; Benzylpenicillin; Clarithromycin; Gentamicin; Phosphate-Sandoz; Hydrocortisone; Lansoprazole; Ipratropium; Salbutamol; Omeprazole; Lactulose; Phenytoin; Fludrocortisone; Loperamide; Enoxaparin



Possible Piperacillin and Tazobactam side effects in 62 year old male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-04-16

Patient: 62 year old male

Reactions: Hypercholesterolaemia, Dyslipidaemia, Anaphylactic Reaction, Kounis Syndrome

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam

Other drugs received by patient: Theophylline; Methylprednisolone; Furosemide



Possible Piperacillin and Tazobactam side effects in 79 year old male

Reported by a pharmacist from United States on 2012-04-10

Patient: 79 year old male, weighing 66.0 kg (145.2 pounds)

Reactions: Vomiting, Nausea, Neutropenia, Leukopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Metronidazole
    Dosage: 500 mg tid po
    Administration route: Oral
    Indication: Urosepsis
    Start date: 2011-11-29
    End date: 2011-12-05

Piperacillin and Tazobactam
    Dosage: 4.5 gm qid iv
    Indication: Urosepsis
    Start date: 2011-11-22
    End date: 2011-12-05



Possible Piperacillin and Tazobactam side effects in 70 year old male

Reported by a pharmacist from United States on 2012-04-10

Patient: 70 year old male, weighing 67.3 kg (148.1 pounds)

Reactions: Thrombocytopenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Piperacillin and Tazobactam



Possible Piperacillin and Tazobactam side effects in 62 year old male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-04-06

Patient: 62 year old male

Reactions: Kounis Syndrome

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam

Other drugs received by patient: Methylprednisolone Hemisuccinate; Theophylline; Furosemide



Possible Piperacillin and Tazobactam side effects in 88 year old female

Reported by a physician from Italy on 2012-04-02

Patient: 88 year old female

Reactions: Blood Sodium Increased

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Piperacillin and Tazobactam



Possible Piperacillin and Tazobactam side effects in female

Reported by a pharmacist from Netherlands on 2012-03-28

Patient: female, weighing 47.0 kg (103.4 pounds)

Reactions: Haemolytic Anaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Azithromycin
    Indication: Antibiotic Prophylaxis
    Start date: 2010-11-01

Azithromycin
    Start date: 2012-01-31
    End date: 2012-02-08

Piperacillin and Tazobactam
    Dosage: 4 dosage forms; 4000mg/500mg
    Indication: Infective Pulmonary Exacerbation of Cystic Fibrosis
    Start date: 2012-01-31
    End date: 2012-02-07

Other drugs received by patient: Novorapid Flexpen Injvlst 100e / ML Wwsp 3ML; Calcichew Kauwtablet 500mg; Foradil Aerosol; Pantoprazol PCH Tablet Msr40mg; Ferro-Gradumet MGA 105mg FE; Alprazolam CF Tablet 0,5mg; Prednisolon PCH Tablet 5MG; Codeine Tablet 20mg; Seroxat Tablet Filmomhuld; Lantus Solostar INJ 100e / ML Wwsp 3ML; Azactam Injectiepoeder Flac 1000mg; Creon Forte Capsule MGA (Pancreatine 300mg); Ursochol Tablet 450mg; Nexium IV Injectiepoeder Flacon 40mg; Actonel Wekelijks Tablet Filmomhuld 35mg



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