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Phenytoin (Phenytoin) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (40)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Phenytoin where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 40   Next >>

Possible Phenytoin side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-27

Patient: female

Reactions: Drug Interaction, Convulsion

Drug(s) suspected as cause:
(Enzyme Inhibitors)
    Dosage: 960 (unit not reported), twice a day
    Indication: Malignant Melanoma

Phenytoin
    Indication: Nervous System Disorder



Possible Phenytoin side effects in female

Reported by a pharmacist from United Kingdom on 2012-07-26

Patient: female

Reactions: Drug Interaction, Convulsion

Drug(s) suspected as cause:
Phenytoin
    Indication: Nervous System Disorder

Zelboraf
    Indication: Malignant Melanoma



Possible Phenytoin side effects in female

Reported by a pharmacist from United Kingdom on 2012-07-24

Patient: female

Reactions: Drug Interaction, Condition Aggravated, Convulsion

Drug(s) suspected as cause:
Phenytoin

Other drugs received by patient possibly interacting with the suspect drug:
Zelboraf
    Dosage: 960 unk, 2x/day
    Indication: Malignant Melanoma



Possible Phenytoin side effects in female

Reported by a pharmacist from United Kingdom on 2012-07-23

Patient: female

Reactions: Condition Aggravated, Drug Interaction, Convulsion

Drug(s) suspected as cause:
Phenytoin

Other drugs received by patient possibly interacting with the suspect drug:
Vemurafenib
    Dosage: 960 unk, 2x/day
    Indication: Malignant Melanoma



Possible Phenytoin side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-28

Patient: female, weighing 63.6 kg (139.8 pounds)

Reactions: Abdominal Pain, Weight Decreased, Urinary Incontinence, Blood Count Abnormal, Headache, Loss of Consciousness, Palpitations, Feeling Hot, Ingrowing Nail, Gallbladder Disorder, Nervousness, Anaemia, Hypoaesthesia, Gastric Disorder, Convulsion, Insomnia, Cholecystectomy, Platelet Count Decreased, Drug Ineffective, Blood Triglycerides Increased, Drug Interaction, Micturition Frequency Decreased, Fall, Dizziness, Arterial Occlusive Disease, Kidney Infection, TOE Operation, Blood Pressure Increased, Lung Neoplasm, Arteriogram Coronary Abnormal, Cystitis, Full Blood Count Decreased, Haemoglobin Decreased, Burning Sensation, Carbuncle, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amlodipine Besylate
    Administration route: Oral
    Start date: 1997-01-01

Amlodipine Besylate
    Administration route: Oral
    Start date: 2010-01-01

Amlodipine Besylate
    Administration route: Oral
    Start date: 2010-07-19
    End date: 2010-07-21

Amlodipine Besylate
    Administration route: Oral

Amlodipine Besylate
    Administration route: Oral
    Start date: 2010-07-22

Amlodipine Besylate
    Administration route: Oral
    Indication: Hypertension
    Start date: 1994-01-01

Atacand
    Dosage: 32mg daily
    Administration route: Oral
    Indication: Renal Disorder
    Start date: 1995-01-01

Atacand
    Administration route: Oral
    Start date: 2011-09-01

Atacand

Avapro
    Indication: Hypertension

Bactrim
    Indication: Product Used FOR Unknown Indication

Benicar
    Dosage: film-coated
    Administration route: Oral
    Indication: Hypertension
    Start date: 2007-01-01

Cardizem
    Dosage: extended release
    Indication: Product Used FOR Unknown Indication

Ciprofloxacin Hydrochloride
    Indication: Product Used FOR Unknown Indication

Depakote
    Indication: Convulsion
    Start date: 1995-01-01
    End date: 2004-01-01

Furosemide
    Indication: Product Used FOR Unknown Indication

Furosemide

Hydrochlorothiazide
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-03-07

Levaquin
    Indication: Product Used FOR Unknown Indication

Lidocaine
    Indication: Ingrowing Nail
    Start date: 2010-05-13
    End date: 2010-05-13

Lidocaine
    Indication: Anaesthesia

Lisinopril
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Losartan Potassium
    Indication: Product Used FOR Unknown Indication

Macrobid
    Indication: Product Used FOR Unknown Indication

Nebivolol Hydrochloride
    Indication: Product Used FOR Unknown Indication

Nopalea (Plant Alkaloids and Other Natural Products)
    Indication: Arthralgia
    Start date: 2010-01-01

Nopalea (Plant Alkaloids and Other Natural Products)
    Indication: Blood Triglycerides Increased

Phenytoin
    Indication: Convulsion
    Start date: 1995-01-01

Reglan
    Indication: Product Used FOR Unknown Indication

Toprol-XL
    Indication: Flushing

Toprol-XL
    Dosage: 25mg daily
    Administration route: Oral
    Indication: Heart Rate Abnormal

Valsartan
    Indication: Product Used FOR Unknown Indication

Xanax
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Levothyroxine Sodium; Clonidine; Metoprolol Succinate; Clonidine



Possible Phenytoin side effects in 21 year old male

Reported by a health professional (non-physician/pharmacist) from India on 2012-06-25

Patient: 21 year old male

Reactions: Cerebellar Ataxia, Drug Interaction, Toxicity To Various Agents, Speech Disorder, Intention Tremor, Nystagmus, Hypotonia, Vision Blurred, Gait Disturbance, Coordination Abnormal

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Methaqualone (Methaqualone)
    Dosage: 250 mg;bid

Phenytoin
    Dosage: 300 mg;qd;po
    Administration route: Oral
    Indication: Epilepsy



Possible Phenytoin side effects in 21 year old male

Reported by a physician from India on 2012-06-22

Patient: 21 year old male

Reactions: Ataxia, Drug Interaction, Toxicity To Various Agents, Cerebellar Atrophy, Grand MAL Convulsion, Dysarthria, Anticonvulsant Drug Level Above Therapeutic, Intention Tremor, Nystagmus, Hypotonia, Vision Blurred, Gait Disturbance, Coordination Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methaqualone TAB
    Dosage: 250 mg;bid;

Phenytoin
    Dosage: 300 mg;qd; 300 mg;qd;
    Indication: Epilepsy

Phenytoin
    Dosage: 300 mg;qd; 300 mg;qd;
    Indication: Epilepsy



Possible Phenytoin side effects in 53 year old male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-06-21

Patient: 53 year old male

Reactions: Electrocardiogram ST Segment Depression, Anaesthetic Complication, Coronary Artery Disease, Drug Interaction, Toxicity To Various Agents, Electrocardiogram QRS Complex Abnormal, Electrocardiogram ST Segment Elevation, Haemodynamic Instability

Drug(s) suspected as cause:
Phenytoin
    Dosage: unk
    Indication: Status Epilepticus

Valproate Sodium
    Dosage: unk, intravenous
    Indication: Status Epilepticus

Other drugs received by patient: Inotropic Agents



Possible Phenytoin side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-19

Patient: female, weighing 63.6 kg (139.8 pounds)

Reactions: Abdominal Pain, Weight Decreased, Urinary Incontinence, Blood Count Abnormal, Headache, Loss of Consciousness, Palpitations, Feeling Hot, Ingrowing Nail, Gallbladder Disorder, Nervousness, Anaemia, Hypoaesthesia, Gastric Disorder, Convulsion, Insomnia, Platelet Count Decreased, Cholecystectomy, Drug Ineffective, Blood Triglycerides Increased, Drug Interaction, Micturition Frequency Decreased, Fall, Dizziness, Arterial Occlusive Disease, TOE Operation, Kidney Infection, Blood Pressure Increased, Lung Neoplasm, Arteriogram Coronary Abnormal, Cystitis, Full Blood Count Decreased, Burning Sensation, Haemoglobin Decreased, Carbuncle, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amlodipine Besylate
    Administration route: Oral
    Start date: 2010-01-01

Amlodipine Besylate
    Administration route: Oral
    Indication: Hypertension
    Start date: 1994-01-01

Amlodipine Besylate
    Dosage: film coated
    Administration route: Oral
    Start date: 2010-07-22

Amlodipine Besylate
    Dosage: film coated
    Administration route: Oral

Amlodipine Besylate
    Dosage: film coated
    Administration route: Oral
    Start date: 2010-07-19
    End date: 2010-07-21

Amlodipine Besylate
    Administration route: Oral
    Start date: 1997-01-01

Atacand
    Administration route: Oral
    Indication: Renal Disorder
    Start date: 2011-09-01

Atacand
    Dosage: daily
    Administration route: Oral
    Indication: Hypertension
    Start date: 1995-01-01
    End date: 2011-03-01

Avapro
    Indication: Hypertension

Bactrim
    Indication: Product Used FOR Unknown Indication

Benicar
    Dosage: film-coated
    Administration route: Oral
    Indication: Hypertension
    Start date: 2007-01-01

Cardizem
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Ciprofloxacin Hydrochloride
    Indication: Product Used FOR Unknown Indication

Depakote
    Indication: Convulsion
    Start date: 1995-01-01
    End date: 2004-01-01

Furosemide

Furosemide
    Indication: Product Used FOR Unknown Indication

Hydrochlorothiazide
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-03-07

Levaquin
    Indication: Product Used FOR Unknown Indication

Lidocaine
    Indication: Ingrowing Nail
    Start date: 2010-05-13
    End date: 2010-05-13

Lidocaine
    Indication: Anaesthesia

Lisinopril
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Losartan Potassium
    Indication: Product Used FOR Unknown Indication

Macrobid
    Indication: Product Used FOR Unknown Indication

Nebivolol Hydrochloride
    Indication: Product Used FOR Unknown Indication

Nopalea (Plant Alkaloids and Other Natural Products)
    Indication: Arthralgia
    Start date: 2010-01-01

Nopalea (Plant Alkaloids and Other Natural Products)
    Indication: Blood Triglycerides Increased

Phenytoin
    Indication: Convulsion

Reglan
    Indication: Product Used FOR Unknown Indication

Toprol-XL
    Indication: Flushing

Toprol-XL
    Administration route: Oral
    Indication: Heart Rate Abnormal

Valsartan
    Indication: Product Used FOR Unknown Indication

Xanax
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Metoprolol Succinate; Clonidine; Clonidine; Levothyroxine Sodium



Possible Phenytoin side effects in 53 year old male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-06-14

Patient: 53 year old male

Reactions: Electrocardiogram ST Segment Depression, Coronary Artery Disease, Drug Interaction, Toxicity To Various Agents, Electrocardiogram ST Segment Elevation, Haemodynamic Instability

Drug(s) suspected as cause:
Phenytoin
    Indication: Status Epilepticus

Valproate Sodium
    Dosage: intravenous (otherwise not specified)
    Indication: Status Epilepticus

Other drugs received by patient: Inotropic Agents



Possible Phenytoin side effects in 53 year old male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-05-29

Patient: 53 year old male

Reactions: Electrocardiogram Abnormal, Drug Interaction, Toxicity To Various Agents

Drug(s) suspected as cause:
Phenytoin

Other drugs received by patient possibly interacting with the suspect drug:
Valproic Acid
    Indication: Status Epilepticus



Possible Phenytoin side effects in 21 year old male

Reported by a health professional (non-physician/pharmacist) from India on 2012-04-24

Patient: 21 year old male

Reactions: Vestibular Disorder, Drug Interaction, Toxicity To Various Agents, Cerebellar Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Phenytoin

Other drugs received by patient possibly interacting with the suspect drug:
Mandrax



Possible Phenytoin side effects in male

Reported by a physician from United States on 2012-04-02

Patient: male, weighing 2.4 kg (5.3 pounds)

Reactions: Metabolic Acidosis, Ventricular Arrhythmia, Drug Interaction, Atrioventricular Block, Toxicity To Various Agents, Sinus Bradycardia, Long QT Syndrome Congenital

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amiodarone HCL
    Dosage: 1 mg/kg; 3 mg;11 times; 1 mg/kg;3 times;
    Indication: Torsade DE Pointes

Lidocaine
    Dosage: 1 mg/kg; 10 ug/kg; 40 ug/kg; 1 mg/kg;2 times; 50 ug/kg; 1 mg/kg; iv
    Indication: Ventricular Tachycardia

Phenytoin
    Dosage: 8 mg/kg; 5 mg/kg;
    Indication: Ventricular Tachycardia

Other drugs received by patient: Potassium; Dopamine HCL; Vecuronium Bromide; Fentanyl Citrate; Magnesium; Calcium Gluconate; 5% Albumin; Esmolol HCL; Milrinone; Isoproterenol HCL



Possible Phenytoin side effects in 36 year old female

Reported by a individual with unspecified qualification on 2012-03-30

Patient: 36 year old female

Reactions: Neurotoxicity, Diplopia, Balance Disorder, Drug Interaction, Anticonvulsant Drug Level Decreased, Convulsion

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lacosamide
    Dosage: unknown, 100 mg, 1 in 1 d, unknown, unknown
    Indication: Epilepsy

Oxcarbazepine
    Dosage: unknown, 1200 milligram, 1 in 1 d, unknown, 300 milligram, 1 in d, unknown
    Indication: Epilepsy

Phenytoin
    Dosage: unknown
    Indication: Epilepsy

Topiramate
    Dosage: oral use
    Administration route: Oral
    Indication: Epilepsy



Possible Phenytoin side effects in 59 year old male

Reported by a individual with unspecified qualification from Japan on 2012-03-28

Patient: 59 year old male

Reactions: Drug Level Increased, Nausea, Condition Aggravated, Drug Interaction, Toxicity To Various Agents, Treatment Noncompliance, Convulsion, Dyslalia, Anxiety, Insomnia, Hypophagia, Dizziness, Gastrooesophageal Reflux Disease

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lansoprazole
    Dosage: 15 mg (15 mg, 1 in 1 d)
    Administration route: Oral
    Indication: Gastrooesophageal Reflux Disease
    Start date: 2011-09-02
    End date: 2012-02-09

Phenytoin
    Dosage: 300 mg (100 mg, 3 in 1 d) 200 mg (200 mg, 1 d), 225 mg (225 mg, 1 d)
    Administration route: Oral
    Indication: Epilepsy
    Start date: 1994-01-01
    End date: 2012-02-02

Phenytoin
    Dosage: 300 mg (100 mg, 3 in 1 d) 200 mg (200 mg, 1 d), 225 mg (225 mg, 1 d)
    Administration route: Oral
    Indication: Epilepsy
    Start date: 2012-02-03
    End date: 2012-02-17

Phenytoin
    Dosage: 300 mg (100 mg, 3 in 1 d) 200 mg (200 mg, 1 d), 225 mg (225 mg, 1 d)
    Administration route: Oral
    Indication: Epilepsy
    Start date: 2012-02-18



Possible Phenytoin side effects in 44 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-03-26

Patient: 44 year old female, weighing 63.5 kg (139.7 pounds)

Reactions: Vomiting, Diarrhoea, Nausea, Dehydration, Drug Interaction, Rash

Drug(s) suspected as cause:
Phenytoin

Other drugs received by patient possibly interacting with the suspect drug:
Zonegran
    Dosage: unknown
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-07-07
    End date: 2010-01-01

Zonegran
    Dosage: 100mg in am, 150mg in pm
    Administration route: Oral
    Start date: 2010-01-01
    End date: 2010-09-28

Other drugs received by patient: Pregabalin



Possible Phenytoin side effects in 44 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-03-22

Patient: 44 year old female, weighing 63.5 kg (139.7 pounds)

Reactions: Vomiting, Diarrhoea, Nausea, Dehydration, Drug Interaction, Rash

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Phenytoin

Other drugs received by patient possibly interacting with the suspect drug:
Zonegran
    Dosage: 100mg in am, 150mg in pm
    Administration route: Oral
    Start date: 2010-01-01
    End date: 2010-09-28

Zonegran
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-07-07
    End date: 2010-01-01

Other drugs received by patient: Pregabalin



Possible Phenytoin side effects in 64 year old female

Reported by a individual with unspecified qualification from Canada on 2012-03-08

Patient: 64 year old female

Reactions: Colon Cancer Metastatic, Ataxia, Hyperreflexia, Drug Interaction, Anticonvulsant Drug Level Decreased, Toxicity To Various Agents, Somnolence, Balance Disorder, Dizziness, Gait Disturbance

Drug(s) suspected as cause:
Fluorouracil
    Indication: Colon Cancer

Phenytoin
    Indication: Epilepsy

Other drugs received by patient: Calcium Carbonate; Venlafaxine; Etidronate Disodium; Irinotecan HCL; Docusate Sodium; Leucovorin Calcium; Cetuximab



Possible Phenytoin side effects in 21 year old male

Reported by a health professional (non-physician/pharmacist) from India on 2012-03-05

Patient: 21 year old male

Reactions: Anticonvulsant Drug Level Increased, Drug Interaction, Cerebellar Syndrome

Drug(s) suspected as cause:
Phenytoin

Other drugs received by patient possibly interacting with the suspect drug:
Mandrax
    Dosage: 250 mg, 2x/day



Possible Phenytoin side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-03-01

Patient: 65 year old female

Reactions: Dysphagia, Aphasia, Drug Interaction, Encephalopathy, Muscle Spasticity, Somnolence, Incontinence, Apraxia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Phenytoin

Other drugs received by patient possibly interacting with the suspect drug:
Phenytoin
    Dosage: 200mg daily (at bedtime)

Phenytoin
    Dosage: 450 mg daily

Septra DS
    Dosage: sulfamethoxazole 800mg/trimethoprim 160mg twice daily for four 7-day courses
    Indication: Urinary Tract Infection



Possible Phenytoin side effects in male

Reported by a physician from United States on 2012-02-24

Patient: male, weighing 2.4 kg (5.3 pounds)

Reactions: Neurotoxicity, Nasopharyngitis, Drug Interaction, Toxicity To Various Agents, Cardiac Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Amiodarone HCL
    Dosage: 1;3mg/dose, intravenous bolus
    Indication: Ventricular Arrhythmia

Esmolol HCL
    Dosage: 66;30;200;250;500 mcg/kg/min, intravenous drip
    Indication: Ventricular Arrhythmia

Fentanyl Citrate
    Dosage: 5 ug/kg, microgram/kilogram,
    Indication: Anaesthesia

Fentanyl Citrate
    Dosage: 5 ug/kg, microgram/kilogram,
    Indication: Arrhythmia

Lidocaine HCL
    Dosage: 1;40;50 mg/kg milligram(s)/kilogram, intravenous bolus
    Indication: Ventricular Arrhythmia

Magnesium Sulfate
    Dosage: i25 mg/kg per dose, ntravenous bolus
    Indication: Ventricular Arrhythmia

Phenytoin
    Dosage: 8;5mg/kg milligram(s)/kilogram, intravenous bolus
    Indication: Ventricular Arrhythmia

Other drugs received by patient: Potassium Chloride; Sodium Hydrogen Carbonate; Albumin (Human); Clcium Gluconate; Vecuronium Bromide; Isoproterenol Hydrochloride; Milrinone



Possible Phenytoin side effects in 64 year old female

Reported by a physician from Canada on 2012-01-17

Patient: 64 year old female

Reactions: Drug Interaction, Hyperreflexia, Ataxia, Toxicity To Various Agents, Somnolence, Anticonvulsant Drug Level Below Therapeutic, Anticonvulsant Drug Level Above Therapeutic, Balance Disorder, Dizziness, Gait Disturbance

Drug(s) suspected as cause:
Fluorouracil
    Indication: Chemotherapy

Phenytoin
    Dosage: 200 mg; tid; po
    Administration route: Oral
    Indication: Epilepsy

Other drugs received by patient: Venlafaxine HCL Extended-Release; Irinotecan HCL; Etidronate and Calcium Carbonate; Leucovorin Calcium; Docusate Sodium



Possible Phenytoin side effects in 64 year old female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-01-10

Patient: 64 year old female

Reactions: Anticonvulsant Drug Level Above Therapeutic, Balance Disorder, Abasia, Hyperreflexia, Drug Interaction, Dizziness, Ataxia, Toxicity To Various Agents, Somnolence

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 7 cycles
    Indication: Colorectal Cancer Metastatic

Irinotecan HCL
    Dosage: 7 cycles
    Indication: Colorectal Cancer Metastatic

Leucovorin Sodium
    Dosage: 7 cycles
    Indication: Colorectal Cancer Metastatic

Phenytoin
    Dosage: 200 mg;tid
    Indication: Epilepsy
    Start date: 1994-01-01

Other drugs received by patient: Venlafaxine; Etidronate Disodium; Docusate Sodium; Calcium Carbonate



Possible Phenytoin side effects in female

Reported by a consumer/non-health professional from Canada on 2012-01-03

Patient: female, weighing 49.9 kg (109.8 pounds)

Reactions: Weight Decreased, Increased Appetite, Personality Disorder, Nystagmus, Tracheitis, Nervousness, Crying, Lyme Disease, Abnormal Sleep-Related Event, Dysphagia, Pain in Extremity, Ataxia, Toxicity To Various Agents, Hypoaesthesia, Paraesthesia, Areflexia, Hyporeflexia, Central Nervous System Lesion, Dyskinesia, Drug Interaction, Somnolence, Fall, Drop Attacks, Speech Disorder, Fatigue, Anticonvulsant Drug Level Increased, Depression, Sinusitis, Cervix Carcinoma, Drug Effect Increased, Nausea, Cholecystitis Acute, Anticonvulsant Drug Level Decreased, Muscular Weakness, Mental Impairment, Dysarthria, Vibratory Sense Increased, Gait Disturbance, Bronchitis, Blood Pressure Decreased, Feeling Abnormal, Bradyphrenia, Asthenia

Drug(s) suspected as cause:
Bactrim

Carboplatin
    Indication: Cervix Carcinoma
    Start date: 2011-08-01

Clarithromycin

Minocycline HCL

Phenobarbital TAB
    Start date: 1974-11-01
    End date: 2011-10-27

Phenytoin
    Dosage: 78.5714 milligram;
    Administration route: Oral
    Indication: Post-Traumatic Epilepsy
    Start date: 1989-01-01
    End date: 2011-10-27

Phenytoin
    Dosage: 214.2857 milligram; 300 mg, 5 times a week at bedtime
    Administration route: Oral
    Indication: Convulsion
    Start date: 1974-11-01
    End date: 1989-01-01

Other drugs received by patient: Levothyroxine Sodium; Amoxicillin



Possible Phenytoin side effects in female

Reported by a consumer/non-health professional from Canada on 2011-12-29

Patient: female

Reactions: Weight Decreased, Increased Appetite, Personality Disorder, Nystagmus, Tracheitis, Lyme Disease, Crying, Nervousness, Abnormal Sleep-Related Event, Dysphagia, Pain in Extremity, Toxicity To Various Agents, Hypoaesthesia, Paraesthesia, Areflexia, Hyporeflexia, Dyskinesia, Central Nervous System Lesion, Drug Interaction, Somnolence, Fall, Drop Attacks, Speech Disorder, Fatigue, Anticonvulsant Drug Level Increased, Depression, Sinusitis, Cervix Carcinoma, Drug Effect Increased, Cholecystitis Acute, Nausea, Muscular Weakness, Anticonvulsant Drug Level Decreased, Dysarthria, Mental Impairment, Vibratory Sense Increased, Bronchitis, Gait Disturbance, Asthenia, Bradyphrenia, Blood Pressure Decreased, Feeling Abnormal

Drug(s) suspected as cause:
Bactrim

Carboplatin
    Indication: Cervix Carcinoma

Clarithromycin

Minocycline HCL

Phenobarbital TAB
    Start date: 1974-11-01
    End date: 2011-10-27

Phenytoin
    Dosage: 214.2857 milligram; 300 mg, 5 times a week at bedtime
    Administration route: Oral
    Indication: Convulsion
    Start date: 1974-11-01
    End date: 1989-01-01

Phenytoin
    Dosage: 78.5714 milligram;
    Administration route: Oral
    Indication: Post-Traumatic Epilepsy
    Start date: 1989-01-01
    End date: 2011-10-27

Other drugs received by patient: Levothyroxine Sodium; Amoxicillin



Possible Phenytoin side effects in 3 year old female

Reported by a health professional (non-physician/pharmacist) from India on 2011-12-23

Patient: 3 year old female, weighing 10.5 kg (23.1 pounds)

Reactions: Chorea, Drug Interaction, Encephalitis Viral

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Clobazam (NO Pref. Name)
    Dosage: 0.75 mg/kg;qd;po
    Administration route: Oral
    Indication: Convulsion

Phenobarbital TAB
    Dosage: 6 ml;q12h;po
    Administration route: Oral
    Indication: Convulsion

Phenytoin
    Dosage: 4 ml;q12h;po
    Administration route: Oral
    Indication: Convulsion

Other drugs received by patient: Methylprednisolone Acetate; Acyclovir



Possible Phenytoin side effects in 3 year old female

Reported by a health professional (non-physician/pharmacist) from India on 2011-12-21

Patient: 3 year old female, weighing 10.5 kg (23.1 pounds)

Reactions: Haemoglobin Decreased, C-Reactive Protein Increased, Chorea, Drug Interaction, Calcium Ionised Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Acyclovir
    Dosage: 40 mg/kg;qd;

Clobazam (Clobazam)
    Dosage: 0.75 mg/kg;qd;
    Indication: Convulsion

Lorazepam
    Dosage: 0.04 mg/kg;
    Indication: Convulsion

Methylprednisolone
    Dosage: 2 mg/kg;qd;
    Indication: Evidence Based Treatment

Phenobarbital TAB
    Dosage: 5 mg/kg;qd;
    Indication: Convulsion

Phenytoin
    Dosage: 5 mg/kg;qd;iv
    Indication: Convulsion



Possible Phenytoin side effects in 64 year old female

Reported by a health professional (non-physician/pharmacist) from Canada on 2011-12-21

Patient: 64 year old female

Reactions: Anticonvulsant Drug Level Increased, Ataxia, Hyperreflexia, Drug Interaction, Dizziness, Toxicity To Various Agents, Somnolence

Drug(s) suspected as cause:
Phenytoin

Other drugs received by patient possibly interacting with the suspect drug:
Fluorouracil
    Dosage: unk
    Indication: Chemotherapy

Irinotecan HCL
    Dosage: unk

Leucovorin Calcium
    Dosage: unk

Other drugs received by patient: Etidronate Disodium; Calcium Carbonate; Docusate Sodium; Venlafaxine



Possible Phenytoin side effects in 64 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-21

Patient: 64 year old female

Reactions: Blood Alkaline Phosphatase Increased, Grand MAL Convulsion, Drug Level Increased, Hypoalbuminaemia, Drug Interaction, Toxicity To Various Agents, Cholecystitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ceftazidime Hydrate (NO Pref. Name)
    Dosage: 1200 mg
    Indication: Cholecystitis

Clindamycin
    Dosage: 2000 mg
    Indication: Cholecystitis

Pazufloxacin Mesylate (NO Pref. Name)
    Dosage: 1000 mg
    Indication: Cholecystitis

Phenytoin
    Dosage: 250 mg, qd, po
    Administration route: Oral
    Indication: Epilepsy

Valproate Sodium
    Dosage: 400 mg, qd, po
    Administration route: Oral
    Indication: Epilepsy



Possible Phenytoin side effects in 26 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-14

Patient: 26 year old female

Reactions: Hepatic Encephalopathy, Intentional Overdose, Completed Suicide, Acute Hepatic Failure, Brain Oedema, Drug Interaction, Intracranial Pressure Increased

Adverse event resulted in: death

Drug(s) suspected as cause:
Acetaminophen
    Dosage: unk, unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Phenytoin
    Dosage: unk, unk
    Indication: Complex Partial Seizures

Topamax
    Dosage: unk, unk
    Indication: Complex Partial Seizures



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