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Pentasa (Mesalamine) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (9)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Pentasa (Mesalamine) where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Pentasa side effects in 60 year old female

Reported by a physician from United States on 2012-04-11

Patient: 60 year old female, weighing 95.0 kg (209.0 pounds)

Reactions: Agitation, Hypersensitivity, Dyspnoea, Pain in Extremity, Drug Interaction, Erythema, Aggression, Irritability, Affective Disorder, Weight Increased, Ecchymosis, DRY Mouth, Oedema Peripheral

Drug(s) suspected as cause:
Elavil
    Administration route: Oral
    Indication: Muscle Spasms

Elavil
    Administration route: Oral

Lyrica
    Administration route: Oral
    Start date: 2005-01-01
    End date: 2010-07-01

Lyrica
    Administration route: Oral
    Indication: Neuralgia
    Start date: 2010-07-01

Medrol
    Administration route: Oral
    Start date: 2010-11-01
    End date: 2012-02-12

Medrol
    Administration route: Oral
    Start date: 2012-02-13

Medrol
    Administration route: Oral
    Indication: Inflammatory Pain
    Start date: 2010-01-01
    End date: 2010-11-01

Pentasa
    Administration route: Oral

Pentasa
    Administration route: Oral
    Indication: Crohn's Disease

Singulair
    Administration route: Oral
    Indication: Asthma

Other drugs received by patient: Taxol; Oxycodone; Prozac; Omeprazole



Possible Pentasa side effects in female

Reported by a physician from United States on 2012-04-06

Patient: female, weighing 94.3 kg (207.5 pounds)

Reactions: Agitation, Dyspnoea, Hypersensitivity, Pain in Extremity, Drug Interaction, Erythema, Aggression, Irritability, Weight Increased, Face Oedema, Oedema Peripheral, Ecchymosis, DRY Mouth, Drug Administration Error, Feeling Abnormal

Drug(s) suspected as cause:
Amitriptyline Hydrochloride
    Dosage: 25 mg, daily
    Indication: Muscle Spasms

Lyrica
    Dosage: 450 mg in a day
    Administration route: Oral
    Indication: Neuralgia
    Start date: 2005-01-01

Pentasa
    Dosage: 750 mg, 3x/day
    Administration route: Oral
    Indication: Crohn's Disease

Pentasa
    Dosage: 750 mg, 2x/day
    Administration route: Oral

Other drugs received by patient possibly interacting with the suspect drug:
Lyrica
    Dosage: 100 mg, 2x/day
    Administration route: Oral
    Start date: 2010-01-01

Medrol
    Dosage: 4 mg, 2x/day
    Administration route: Oral
    Indication: Arthropathy
    Start date: 2011-11-01
    End date: 2012-02-12

Medrol
    Dosage: 4 mg daily
    Administration route: Oral
    Indication: Inflammatory Pain
    Start date: 2009-01-01
    End date: 2011-01-01

Singulair
    Dosage: unk
    Indication: Asthma

Other drugs received by patient: Omeprazole; Taxol; Prozac; Oxycodone



Possible Pentasa side effects in 16 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-03-28

Patient: 16 year old male, weighing 47.0 kg (103.4 pounds)

Reactions: Drug Interaction, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cotrim
    Indication: Infection Prophylaxis
    Start date: 2011-08-17
    End date: 2011-09-12

Imuran
    Administration route: Oral
    Indication: Colitis Ulcerative
    End date: 2011-10-13

Pentasa
    Administration route: Oral
    End date: 2011-10-13

Pepcid RPD
    Administration route: Oral
    End date: 2011-10-13

Prograf
    Administration route: Oral
    Start date: 2011-08-26
    End date: 2011-08-28

Prograf
    Administration route: Oral
    Indication: Colitis Ulcerative
    Start date: 2011-09-05
    End date: 2011-09-12

Prograf
    Administration route: Oral
    Start date: 2011-09-02
    End date: 2011-09-04

Prograf
    Administration route: Oral
    Start date: 2011-08-29
    End date: 2011-09-01

Prograf
    Administration route: Oral
    Start date: 2011-08-17
    End date: 2011-08-25

Other drugs received by patient: Prednisolone



Possible Pentasa side effects in 16 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-03-23

Patient: 16 year old male, weighing 47.0 kg (103.4 pounds)

Reactions: Pancytopenia, Drug Interaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cotrim
    Indication: Infection Prophylaxis
    Start date: 2011-08-17
    End date: 2011-09-12

Imuran
    Administration route: Oral
    Indication: Colitis Ulcerative
    End date: 2011-10-13

Pentasa
    Administration route: Oral
    End date: 2011-10-13

Pepcid RPD
    Administration route: Oral
    End date: 2011-10-13

Prograf
    Administration route: Oral
    Indication: Colitis Ulcerative
    Start date: 2011-09-05
    End date: 2011-09-12

Prograf
    Administration route: Oral
    Start date: 2011-08-29
    End date: 2011-09-01

Prograf
    Administration route: Oral
    Start date: 2011-08-26
    End date: 2011-08-28

Prograf
    Administration route: Oral
    Start date: 2011-09-02
    End date: 2011-09-04

Prograf
    Administration route: Oral
    Start date: 2011-08-17
    End date: 2011-08-25

Other drugs received by patient: Prednisolone



Possible Pentasa side effects in 16 year old male

Reported by a physician from Japan on 2012-03-19

Patient: 16 year old male, weighing 47.0 kg (103.4 pounds)

Reactions: Drug Interaction, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cotrim
    Dosage: 1 df, bid
    Administration route: Oral
    Indication: Infection Prophylaxis
    Start date: 2011-08-17
    End date: 2011-09-12

Famotidine
    Dosage: 20 mg, bid
    Administration route: Oral
    End date: 2011-10-13

Pentasa
    Dosage: 1000 mg, tid
    Administration route: Oral
    Indication: Colitis Ulcerative
    End date: 2011-10-13

Other drugs received by patient possibly interacting with the suspect drug:
Imuran
    Dosage: 50 mg, tid
    Administration route: Oral
    Indication: Colitis Ulcerative
    End date: 2011-10-13

Prograf
    Dosage: 8 mg, unknown/d
    Administration route: Oral
    Start date: 2011-08-26
    End date: 2011-08-28

Prograf
    Dosage: 6 mg, unknown/d
    Administration route: Oral
    Start date: 2011-09-02
    End date: 2011-09-04

Prograf
    Dosage: 7 mg, unknown/d
    Administration route: Oral
    Indication: Colitis Ulcerative
    Start date: 2011-09-05
    End date: 2011-09-12

Prograf
    Dosage: 7 mg, unknown/d
    Administration route: Oral
    Start date: 2011-08-29
    End date: 2011-09-01

Prograf
    Dosage: 2.5 mg, bid
    Administration route: Oral
    Start date: 2011-08-17
    End date: 2011-08-25

Other drugs received by patient: Prednisolone



Possible Pentasa side effects in 60 year old female

Reported by a physician from United States on 2012-03-16

Patient: 60 year old female, weighing 95.0 kg (209.0 pounds)

Reactions: Agitation, Dyspnoea, Hypersensitivity, Pain in Extremity, Drug Interaction, Erythema, Aggression, Affective Disorder, Irritability, Weight Increased, DRY Mouth, Ecchymosis, Oedema Peripheral

Drug(s) suspected as cause:
Elavil
    Administration route: Oral
    Indication: Muscle Spasms

Elavil
    Administration route: Oral

Lyrica
    Administration route: Oral
    Start date: 2005-01-01
    End date: 2010-07-01

Lyrica
    Administration route: Oral
    Indication: Neuralgia
    Start date: 2010-07-01

Medrol
    Administration route: Oral
    Start date: 2010-11-01
    End date: 2012-02-12

Medrol
    Administration route: Oral
    Start date: 2012-02-13

Medrol
    Administration route: Oral
    Indication: Inflammatory Pain
    Start date: 2010-01-01
    End date: 2010-11-01

Pentasa
    Administration route: Oral
    Indication: Crohn's Disease

Pentasa
    Administration route: Oral

Singulair
    Administration route: Oral
    Indication: Asthma

Other drugs received by patient: Prozac; Oxycodone; Omeprazole; Taxol



Possible Pentasa side effects in female

Reported by a consumer/non-health professional from United States on 2012-03-12

Patient: female, weighing 94.3 kg (207.5 pounds)

Reactions: Swelling Face, Hypersensitivity, Dyspnoea, Pain, Drug Interaction, Erythema, Treatment Noncompliance, Weight Increased, Off Label Use, Mood Altered, Ecchymosis, DRY Mouth, Oedema Peripheral, Emotional Disorder

Drug(s) suspected as cause:
Amitriptyline HCL
    Dosage: 25 mg, 1x/day:qd
    Indication: Muscle Spasms

Amitriptyline HCL
    Dosage: 10 mg, 1x/day:qd

Lyrica
    Dosage: 450 mg, unknown
    Administration route: Oral
    Indication: Neuralgia
    Start date: 2005-01-01

Lyrica
    Dosage: 100 mg, 2x/day:bid
    Administration route: Oral

Medrol
    Dosage: 4 mg, 2x/day:bid
    Administration route: Oral
    Indication: Arthralgia
    Start date: 2011-11-01

Medrol
    Dosage: 4 mg, 1x/day:qd
    Administration route: Oral
    Start date: 2012-02-13

Medrol
    Dosage: 4 mg, 1x/day:qd
    Administration route: Oral
    End date: 2011-11-01

Medrol
    Dosage: 4 mg, unknown
    Administration route: Oral
    Indication: Inflammatory Pain

Pentasa
    Dosage: 750 mg (three 250 mg capsules), 2x/day:bid
    Administration route: Oral
    Indication: Crohn's Disease

Singulair
    Dosage: unk, unknown
    Indication: Asthma

Other drugs received by patient: Omeprazole; Oxycodone HCL; Taxol; Oxycodone HCL; Prozac



Possible Pentasa side effects in female

Reported by a physician from United States on 2012-02-22

Patient: female, weighing 94.3 kg (207.5 pounds)

Reactions: Agitation, Hypersensitivity, Dyspnoea, Pain in Extremity, Drug Interaction, Erythema, Aggression, Weight Increased, Irritability, Face Oedema, Ecchymosis, Oedema Peripheral, DRY Mouth, Drug Administration Error, Feeling Abnormal

Drug(s) suspected as cause:
Amitriptyline HCL
    Dosage: 25 mg, daily
    Indication: Muscle Spasms

Pentasa
    Dosage: 750 mg, 3x/day
    Administration route: Oral
    Indication: Crohn's Disease

Pentasa
    Dosage: 750 mg, 2x/day
    Administration route: Oral

Other drugs received by patient possibly interacting with the suspect drug:
Lyrica
    Dosage: 100 mg, 2x/day
    Administration route: Oral
    Start date: 2010-01-01

Lyrica
    Dosage: 450 mg in a day
    Administration route: Oral
    Indication: Neuralgia
    Start date: 2005-01-01

Medrol
    Dosage: 4 mg, 2x/day
    Administration route: Oral
    Indication: Arthropathy
    Start date: 2011-11-01
    End date: 2012-02-12

Medrol
    Dosage: 4 mg daily
    Administration route: Oral
    Indication: Inflammatory Pain
    Start date: 2009-01-01
    End date: 2011-01-01

Singulair
    Dosage: unk
    Indication: Asthma

Other drugs received by patient: Oxycodone; Omeprazole; Taxol; Prozac



Possible Pentasa side effects in female

Reported by a physician from United States on 2012-02-21

Patient: female, weighing 94.3 kg (207.5 pounds)

Reactions: Agitation, Dyspnoea, Hypersensitivity, Pain in Extremity, Drug Interaction, Erythema, Aggression, Irritability, Weight Increased, Face Oedema, Oedema Peripheral, DRY Mouth, Ecchymosis, Drug Administration Error, Feeling Abnormal

Drug(s) suspected as cause:
Lyrica
    Dosage: 450 mg in a day
    Administration route: Oral
    Indication: Neuralgia
    Start date: 2005-01-01

Pentasa
    Dosage: 750 mg, 3x/day
    Administration route: Oral
    Indication: Crohn's Disease

Other drugs received by patient possibly interacting with the suspect drug:
Amitriptyline HCL
    Dosage: 25 mg, daily
    Indication: Muscle Spasms

Lyrica
    Dosage: 100 mg, 2x/day
    Start date: 2010-01-01

Medrol
    Dosage: 4 mg, 2x/day
    Indication: Arthropathy
    Start date: 2011-11-01
    End date: 2012-02-13

Medrol
    Dosage: 4 mg daily
    Administration route: Oral
    Indication: Inflammatory Pain
    Start date: 2009-01-01

Singulair
    Dosage: unk
    Indication: Asthma

Other drugs received by patient: Prozac; Omeprazole; Oxycodone; Taxol

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