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Index of reports
> Cases with Neutropenia (92)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Paclitaxel where reactions include neutropenia. The selected reports were submitted to the FDA during the sample period of about a year. Reports 1 - 30 of 92 Next >>
Possible Paclitaxel side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24
Patient: female
Reactions: Pneumocystis Jiroveci Pneumonia, Maternal Exposure During Pregnancy, Neutropenia, Premature Labour
Drug(s) suspected as cause:
Adriamycin PFS
Indication: Breast Cancer Stage II
Paclitaxel
Indication: Breast Cancer Stage II
Cytoxan
Indication: Breast Cancer Stage II
Possible Paclitaxel side effects in
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-20
Patient:
Reactions: Abdominal Pain, Vomiting, Hypersensitivity, Nausea, Skin Toxicity, Mucosal Inflammation, Fatigue, Diarrhoea, Hepatotoxicity, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Lapatinib
Dosage: arm b
Administration route: Oral
Indication: Breast Cancer
Cyclophosphamide
Indication: Breast Cancer
Lapatinib
Dosage: arm c
Administration route: Oral
Herceptin
Dosage: loading dose
Indication: Breast Cancer
Herceptin
Dosage: maintenance dose
Fluorouracil
Indication: Breast Cancer
Paclitaxel
Indication: Breast Cancer
Epirubicin
Indication: Breast Cancer
Possible Paclitaxel side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-09
Patient: female
Reactions: Vomiting, Febrile Neutropenia, Toxicity To Various Agents, Peripheral Sensory Neuropathy, Haematotoxicity, Diarrhoea, Neutropenia, Thrombocytopenia
Drug(s) suspected as cause:
Paclitaxel
Dosage: on day 2
Indication: Endometrial Cancer
Cisplatin
Dosage: on day 1
Indication: Endometrial Cancer
Doxorubicin Hydrochloride
Dosage: on day 1
Indication: Endometrial Cancer
Other drugs received by patient: Growth Hormone
Possible Paclitaxel side effects in 77 year old male
Reported by a physician from United States on 2012-08-08
Patient: 77 year old male, weighing 66.6 kg (146.5 pounds)
Reactions: Pneumonia, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Avastin
Dosage: date of last dos prior to sae: 13/feb/2012,
Indication: Neoplasm
GDC-0980 (Pi3k / Mtor Inhibitor)
Dosage: last dose: 25 mg, date of last dose prior to sae 5/apr/2012
Administration route: Oral
Indication: Neoplasm
Carboplatin
Dosage: last dose: 648 mg, date of last dos prior to sae:13/feb/2012, last dose: 03/apr/2012
Indication: Neoplasm
Paclitaxel
Dosage: last dose: 360 mg, date of last dose prior to sae: 13/feb/2012, last dose: 05/apr/2012
Indication: Neoplasm
Other drugs received by patient: Ondansetron; Naproxen (Aleve); Zantac; Milk OF Magnesia TAB; Acyclovir; Restoril; Imodium; Ondansetron; Plavix; Dicyclomine
Possible Paclitaxel side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31
Patient: female
Reactions: Hypophosphataemia, Fatigue, Tinnitus, Clostridium Difficile Colitis, Neutropenia, Thrombocytopenia, Klebsiella Bacteraemia
Drug(s) suspected as cause:
Carboplatin
Dosage: auc 7 reconstituted with one liter normal saline (day 1;repeated every 21 days),intraperitoneal
Indication: Ovarian Cancer
Carboplatin
Dosage: auc 7 reconstituted with one liter normal saline (day 1;repeated every 21 days),intraperitoneal
Indication: Malignant Peritoneal Neoplasm
Carboplatin
Dosage: auc 7 reconstituted with one liter normal saline (day 1;repeated every 21 days),intraperitoneal
Indication: Fallopian Tube Cancer
Paclitaxel
Dosage: 60 mg/m2 reconstituted with one liter normal saline (day 8; repeated every 21 days),intraperitoneal
Indication: Ovarian Cancer
Paclitaxel
Dosage: 60 mg/m2 reconstituted with one liter normal saline (day 8; repeated every 21 days),intraperitoneal
Indication: Fallopian Tube Cancer
Paclitaxel
Dosage: 175 mg/m2 (day 1;repeated every 21 days),intravenous
Indication: Fallopian Tube Cancer
Paclitaxel
Dosage: 175 mg/m2 (day 1;repeated every 21 days),intravenous
Indication: Ovarian Cancer
Possible Paclitaxel side effects in male
Reported by a physician from United States on 2012-07-23
Patient: male, weighing 84.0 kg (184.8 pounds)
Reactions: White Blood Cell Count Decreased, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: 760 mg
End date: 2011-02-10
Carboplatin
Dosage: 1293 mg
End date: 2011-02-10
Other drugs received by patient: ...
Possible Paclitaxel side effects in male
Reported by a physician from United States on 2012-07-23
Patient: male, weighing 84.1 kg (185.0 pounds)
Reactions: White Blood Cell Count Decreased, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Carboplatin
Dosage: 1294 mg
End date: 2010-12-30
Paclitaxel
Dosage: 760 mg
End date: 2010-12-30
Possible Paclitaxel side effects in
Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-07-19
Patient:
Reactions: Stomatitis, Alanine Aminotransferase Increased, Febrile Neutropenia, Fatigue, Aspartate Aminotransferase Increased, Neutropenia, Thrombocytopenia, Leukopenia, Decreased Appetite
Drug(s) suspected as cause:
Gemcitabine Hydrochloride
Dosage: on days 1 and 8 every 21 days
Indication: Breast Cancer
Herceptin
Dosage: within 2 weeks after curative surgery until 52 weeks of therapy was completed
Paclitaxel
Dosage: over 1 h on days 1 and 8 every 21 days
Indication: Breast Cancer
Herceptin
Dosage: over 90 min on day 1
Indication: Breast Cancer
Herceptin
Dosage: over 30 min weekly
Possible Paclitaxel side effects in female
Reported by a individual with unspecified qualification from United States on 2012-07-18
Patient: female, weighing 60.0 kg (132.0 pounds)
Reactions: Urinary Tract Infection, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: 810.25 mg
Cisplatin
Dosage: 231.5 mg
Other drugs received by patient: Insuline; Paroxetine HCL
Possible Paclitaxel side effects in
Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-07-18
Patient:
Reactions: Stomatitis, Alanine Aminotransferase Increased, Febrile Neutropenia, Fatigue, Aspartate Aminotransferase Increased, Neutropenia, Thrombocytopenia, Decreased Appetite, Leukopenia
Drug(s) suspected as cause:
Paclitaxel
Indication: Breast Cancer
Paclitaxel
Dosage: dosages were modified to one step lower than the previous level after withholding treatment
Gemcitabine Hydrochloride
Indication: Breast Cancer
Herceptin
Dosage: over 90 min on day 1, followed by 2 mg/kg over 30 min weekly, for a total of 18 doses
Indication: Breast Cancer
Herceptin
Dosage: after curative surgery until 52 weeks of therapy was completed.
Gemcitabine Hydrochloride
Dosage: dosages were modified to one step lower than the previous level after withholding treatment
Possible Paclitaxel side effects in male
Reported by a physician from Japan on 2012-07-12
Patient: male, weighing 57.0 kg (125.4 pounds)
Reactions: Pneumonia, Nasopharyngitis, Rash, Eczema, Pruritus Generalised, Colonic Polyp, Interstitial Lung Disease, Insomnia, Bone Marrow Failure, Neutropenia, Neutrophil Count Decreased, Hypertension
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Start date: 2012-03-15
End date: 2012-03-15
Carboplatin
Start date: 2012-03-15
End date: 2012-03-15
Paclitaxel
Indication: Lung Adenocarcinoma Metastatic
Start date: 2012-03-15
End date: 2012-04-12
Sulbacilline
Indication: Interstitial Lung Disease
Start date: 2012-05-02
End date: 2012-05-09
Avastin
Start date: 2012-02-01
End date: 2012-02-01
Carboplatin
Indication: Lung Adenocarcinoma Metastatic
Start date: 2012-02-01
End date: 2012-02-01
Avastin
Indication: Lung Adenocarcinoma Metastatic
Start date: 2011-12-28
End date: 2011-12-28
Other drugs received by patient: Loxoprofen; Famotidine; Dexamethasone Sodium Phosphate; Restamin; Granisetron; Diclofenac Sodium; Sennoside; Vitamedin; Rebamipide; Zofran
Possible Paclitaxel side effects in male
Reported by a physician from United States on 2012-07-10
Patient: male, weighing 84.1 kg (185.0 pounds)
Reactions: White Blood Cell Count Decreased, Neutropenia
Drug(s) suspected as cause:
Erbitux
Dosage: 2880 mg
End date: 2011-02-24
Carboplatin
Dosage: 1292 mg
End date: 2011-02-10
Paclitaxel
Dosage: 760 mg
End date: 2011-02-10
Possible Paclitaxel side effects in female
Reported by a individual with unspecified qualification from United States on 2012-07-09
Patient: female, weighing 136.5 kg (300.3 pounds)
Reactions: Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: 350 mg
Carboplatin
Dosage: 872 mg
Possible Paclitaxel side effects in 40 year old male
Reported by a consumer/non-health professional from Italy on 2012-06-27
Patient: 40 year old male
Reactions: Malaise, Alopecia, Neutropenia, Hypertransaminasaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Indication: Thymoma
Start date: 2011-06-24
End date: 2011-07-17
Cyclophosphamide
Indication: Thymoma
Start date: 2011-06-24
End date: 2011-07-17
Epirubicin Hydrochloride
Indication: Thymoma
Start date: 2011-06-24
End date: 2011-07-17
Possible Paclitaxel side effects in
Reported by a individual with unspecified qualification from France on 2012-06-26
Patient:
Reactions: Pulmonary Haemorrhage, Neuropathy Peripheral, Intestinal Perforation, Neutropenia, Onycholysis, Hypertension, Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Paclitaxel
Dosage: on days 1, 8, 15
Indication: non-Small Cell Lung Cancer Metastatic
Avastin
Dosage: on day 1
Indication: non-Small Cell Lung Cancer Metastatic
Possible Paclitaxel side effects in female
Reported by a consumer/non-health professional from United States on 2012-06-26
Patient: female, weighing 61.6 kg (135.5 pounds)
Reactions: Cellulitis, Neutropenia, Thrombocytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Gemcitabine Hydrochloride
Dosage: 1000 mg/m2, unk
Indication: Pancreatic Carcinoma Metastatic
Start date: 2012-03-29
Paclitaxel
Dosage: 100 mg/m2, unk
Start date: 2012-05-24
Paclitaxel
Dosage: 125 mg/m2, unk
Indication: Pancreatic Carcinoma Metastatic
Start date: 2012-03-29
Other drugs received by patient: Omeprazole; Lactulose; Lyrica; Enoxaparin Sodium; Enoxaparin Sodium; Plantaben; Lorazepam; Morphine Sulfate; Acetaminophen; Paroxetine HCL; Primperan TAB
Possible Paclitaxel side effects in
Reported by a physician from United States on 2012-06-18
Patient:
Reactions: Transitional Cell Carcinoma, Anaemia, Neutropenia, Thrombocytopenia
Adverse event resulted in: death
Drug(s) suspected as cause:
Pegfilgrastim
Indication: Transitional Cell Carcinoma
Doxorubicin HCL
Paclitaxel
Indication: Transitional Cell Carcinoma
Gemcitabine
Indication: Transitional Cell Carcinoma
Doxorubicin HCL
Indication: Transitional Cell Carcinoma
Possible Paclitaxel side effects in
Reported by a health professional (non-physician/pharmacist) from Portugal on 2012-06-08
Patient:
Reactions: Haemoptysis, Anaemia, Renal Failure, Embolism, Thrombocytosis, Neutropenia, Hypertension, Thrombocytopenia, Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Indication: non-Small Cell Lung Cancer
Gemcitabine Hydrochloride
Indication: non-Small Cell Lung Cancer
Pemetrexed Disodium
Indication: non-Small Cell Lung Cancer
Paclitaxel
Indication: non-Small Cell Lung Cancer
Possible Paclitaxel side effects in female
Reported by a individual with unspecified qualification from United States on 2012-06-05
Patient: female
Reactions: Vomiting, Wound Dehiscence, Nausea, Pain, Hyperglycaemia, Proteinuria, Ejection Fraction Decreased, Neutropenia, Hypertension, Blood Creatinine Increased, Thrombocytopenia, Infection
Drug(s) suspected as cause:
Herceptin
Dosage: for 23 weeks
Avastin
Dosage: for 23 weeks
Indication: Breast Cancer
Herceptin
Dosage: loading dose
Indication: Breast Cancer
Herceptin
Dosage: total 54 weeks
Paclitaxel
Dosage: days 1, 8 and 15
Indication: Breast Cancer
Avastin
Dosage: total 54 weeks
Carboplatin
Dosage: auc=6 for 6 cycles
Indication: Breast Cancer
Possible Paclitaxel side effects in female
Reported by a physician from France on 2012-06-04
Patient: female
Reactions: Pyrexia, Neutropenia, Radiation Mucositis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Indication: Breast Cancer
Start date: 2012-02-24
End date: 2012-02-24
Avastin
Indication: Breast Cancer
Start date: 2012-02-24
End date: 2012-02-24
Possible Paclitaxel side effects in female
Reported by a individual with unspecified qualification from United States on 2012-05-30
Patient: female, weighing 136.5 kg (300.3 pounds)
Reactions: Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: 350 mg
Carboplatin
Dosage: 872 mg
Possible Paclitaxel side effects in
Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-05-30
Patient:
Reactions: Stomatitis, Alanine Aminotransferase Increased, Febrile Neutropenia, Fatigue, Aspartate Aminotransferase Increased, Neutropenia, Thrombocytopenia, Leukopenia, Decreased Appetite
Drug(s) suspected as cause:
Paclitaxel
Dosage: dosages were modified to one step lower than the previous level after withholding treatment
Gemcitabine Hydrochloride
Indication: Breast Cancer
Herceptin
Dosage: over 90 min on day 1, followed by 2 mg/kg over 30 min weekly, for a total of 18 doses
Indication: Breast Cancer
Herceptin
Dosage: after curative surgery until 52 weeks of therapy was completed.
Paclitaxel
Indication: Breast Cancer
Gemcitabine Hydrochloride
Dosage: dosages were modified to one step lower than the previous level after withholding treatment
Possible Paclitaxel side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-29
Patient: female
Reactions: Thrombosis, Agitation, Headache, Peripheral Sensory Neuropathy, Malaise, Granulocytopenia, Stomatitis, Hyperglycaemia, Anaemia, Intestinal Obstruction, Neutropenia, Bone Pain, Pain, Gastrointestinal Inflammation, Constipation, Hypokalaemia, Fatigue, Depression, Thrombocytopenia, Decreased Appetite, Lethargy, Pharyngitis, Vomiting, Dyspnoea, Nausea, Lymphopenia, Febrile Neutropenia, Palmar-Plantar Erythrodysaesthesia Syndrome, Hyponatraemia, Anxiety, Syncope, Embolism, Diarrhoea, Leukopenia, Infection
Drug(s) suspected as cause:
Granulocyte Colony Stimulating Factor
Indication: Palliative Care
Cyclophosphamide
Administration route: Oral
Doxorubicin HCL
Dosage: 60 mg/m2 for standard arm and 24 mg/m2 for continuous arm
Indication: Breast Cancer
Cyclophosphamide
Indication: Breast Cancer
Paclitaxel
Indication: Breast Cancer
Possible Paclitaxel side effects in
Reported by a individual with unspecified qualification from United States on 2012-05-28
Patient:
Reactions: Pain, Mental Status Changes, Pulmonary Embolism, Constipation, Neuropathy Peripheral, Fatigue, Dyspepsia, Oral Candidiasis, Oedema, Decreased Appetite, Hypovolaemia, Blood Alkaline Phosphatase Increased, Vomiting, Dysphagia, Nausea, Febrile Neutropenia, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Brachial Plexopathy, Anxiety, Mucosal Inflammation, Insomnia, Aspartate Aminotransferase Increased, Dehydration, Neutropenia
Drug(s) suspected as cause:
Paclitaxel
Dosage: on days 1-8
Indication: Breast Cancer Metastatic
Xeloda
Dosage: on days 1-15
Administration route: Oral
Indication: Breast Cancer Metastatic
Possible Paclitaxel side effects in 77 year old male
Reported by a physician from United States on 2012-05-25
Patient: 77 year old male, weighing 66.6 kg (146.5 pounds)
Reactions: Pneumonia, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Carboplatin
Dosage: last dose: 648 mg, date of last dos prior to sae: 05/apr/2012
Indication: Neoplasm
Start date: 2012-02-13
Acyclovir
Indication: Rash
Avastin
Dosage: date of last dos prior to sae: 13/feb/2012
Indication: Neoplasm
GDC-0980 (Pi3k / Mtor Inhibitor)
Dosage: last dose: 25 mg, date of last dos prior to sae: 13 feb 2012
Administration route: Oral
Indication: Neoplasm
Start date: 2012-02-13
Paclitaxel
Dosage: last dose: 360 mg, date of last dos prior to sae: 05/apr/2012
Indication: Neoplasm
Start date: 2012-02-13
Possible Paclitaxel side effects in 59 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-09
Patient: 59 year old male, weighing 44.0 kg (96.8 pounds)
Reactions: Bronchopneumonia, Mouth Ulceration, Anaemia, Neutropenia, Odynophagia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Other drugs received by patient: Megace; Magnesium Oxide
Possible Paclitaxel side effects in 66 year old male
Reported by a consumer/non-health professional from United States on 2012-05-07
Patient: 66 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Abdominal Pain, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Possible Paclitaxel side effects in female
Reported by a individual with unspecified qualification from United States on 2012-05-03
Patient: female
Reactions: Chest Pain, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Indication: Breast Cancer
Cyclophosphamide
Indication: Breast Cancer
Pegfilgrastim
Indication: Breast Cancer
Bevacizumab
Indication: Breast Cancer
Doxorubicin HCL
Indication: Breast Cancer
Bevacizumab
Possible Paclitaxel side effects in 61 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-30
Patient: 61 year old female, weighing 59.4 kg (130.7 pounds)
Reactions: Blood Alkaline Phosphatase Increased, Vomiting, Nausea, Chills, Blood Albumin Decreased, Pyrexia, Neutropenia, Blood Sodium Decreased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Carboplatin
Dosage: auc5/175mg/m2
Indication: Neoplasm Malignant
Start date: 2012-04-09
End date: 2012-04-09
Ridaforolimus
Dosage: 10 mg po
Administration route: Oral
Indication: Neoplasm Malignant
Start date: 2012-04-16
End date: 2012-04-20
Ridaforolimus
Dosage: 10 mg po
Administration route: Oral
Indication: Neoplasm Malignant
Start date: 2012-04-09
End date: 2012-04-13
Possible Paclitaxel side effects in
Reported by a physician from Hungary on 2012-04-19
Patient:
Reactions: Mucosal Inflammation, Diarrhoea, Dehydration, Anaemia, Neutropenia, Thrombocytopenia, Herpes Zoster
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Lapatinib
Administration route: Oral
Indication: Breast Cancer
Paclitaxel
Indication: Breast Cancer
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